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Index of Cleared Science Reviews for Propazine (Pc Code 080808)

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Undated. DER. 7 Pages.
Lisa Austin. Registration Action Branch 1.
In vivo Mammalian Spermatogonial Chromosome Aberration Test-mouse OPPTS
870.5380 [§84-2]; OECD 483. TXR#: 0052927. DP BARCODE: D310325.
MRID No. 46171701.
Document (PDF) (32 KB PDF).

August 07, 1968. Review. 11 Page(s).
R. D. Coberly. Toxicology Branch.
Chemical Name : 2-Chloro-4,6-bis-(isopropylamino) s-triazine Company: Geigy
Tox review 001376.
Document (PDF) (645 KB PDF).

November 22, 1977. Memorandum. 2 Page(s).
J. D. Doherty. Toxicology Branch.
Triox Liquid Vegetation Killer. Caswell #63, 184, 97, 740.
Document (PDF) (212 KB PDF).

January 10, 1978. Review. 9 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
EUP for Sorghum.
Document (PDF) (543 KB PDF).

January 11, 1979. Review. 12 Page(s).
Larry Turner. Efficacy & Ecological Effects Branch.
Experimental Use Permit - Grain, Sorghum.
Document (PDF) (381 KB PDF).

January 19, 1979. Review. 3 Page(s).
Ronald Ney. Environmental Fate Branch.
EUP on Sorghum Grown for Grain. Total Acreage Is 50 Acres.
This Is a Prepackaged Combination Herbicide.
Document (PDF) (159 KB PDF).

February 21, 1979. Memorandum. 4 Page(s).
John Doherty. Toxicology Branch.
EPA No. 100-EUP-AE. Milocep Herbicide (Metolachlor- Propazine Prepack).
Caswell #188DD and #184. Inert ingredient information on page 1 is not included.
Document (PDF) (312 KB PDF).

March 01, 1979. Memorandum. 1 Page(s).
A. R. Rathman. Residue Chemistry Branch.
PP #8G2019. Metolachlor on Grain Sorghum. Request for Extension of Temporary Tolerances.
Document (PDF) (139 KB PDF).

March 07, 1979. Memorandum. 1 Page(s).
John Doherty. Toxicology Branch.
EPA #100-EUP-AE. Milocep, Clarification of Inert...
Inert ingredient information is not included.
Document (PDF) (139 KB PDF).

June 07, 1979. Review. 5 Page(s).
Ronald Ney. Environmental Fate Branch.
New Product.
Document (PDF) (210 KB PDF).

December 21, 1979. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
6(a)(2) Data on Terbutryn and Propazine.
Document (PDF) (95 KB PDF).

January 04, 1980. Memorandum. 1 Page(s).
Robert Coberly. Toxicology Branch.
ALERT MEMO -- re: Propazine - oncogenicity potential.
Document (PDF) (34 KB PDF).

January 14, 1980. Memorandum. 6 Page(s).
Sherell Sterling. Fungicide Herbicide Branch.
EPA File Symbol: 100-ANU. Milocep.
Document (PDF) (468 KB PDF).

July 16, 1980. Review. 32 Page(s).
Curtis Laird. Ecological Effects Branch.
Incremental Risk Assessment for Proposed Conditional Registration Amendments.
Document (PDF) (1158 KB PDF).

June 16, 1981. Memorandum. 21 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. 100-543, Technical Propazine; 6(a)(2) Data Accession 243350-58
Tox review 000575.
Document (PDF) (1136 KB PDF).

October 07, 1983. Review. 18 Pages.
Martha Bradley. Residue Chemistry Branch.
Update Propazine. Acceptable Name: Propazine. Pesticide Reg. Sec. 180.243. Determination
of 2,4-Diamino-6-Chloro-s-Triazine (G-28273) Residues in Crops and Animal Tissue by Gas Chromatography.
Pages 8-18 removed, confidential statement of formula.
Document (PDF) (188 KB PDF).

October 25, 1984. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Ad Hoc Committee Meeting on Longterm Studies of Propazine.
Document (PDF) (53 KB PDF).

July 12, 1985. Memorandum. 29 Page(s).
William Dykstra. Toxicology Branch.
PP# 2F2618; Propazine in/on sorghum; revised Section B and Section F.
Pages 14-15, 17-29 removed, registrant data. Tox review 004542.
Document (PDF) (611 KB PDF).

June 27, 1986. Review. 3 Page(s).
William Dykstra. Toxicology Branch.
Reference Doses (RfDs) for Oral Exposure Chemical: Propazine.
Document (PDF) (114 KB PDF).

July 11, 1986. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
Propazine; PP# 2F2618; Propazine in/on sorghum; Revised Section F; Historical
Control Data and Additional Data.
Document (PDF) (85 KB PDF).

July 22, 1986. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Propazine; PP# 2F2618; Propazine in/on sorghum; Revised NOEL for 2-year rat study
Tox review 005319.
Document (PDF) (105 KB PDF).

September 12, 1986. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Propazine, Caswell No. 184. NOEL for 2-Year Rat Study Tox review 005508.
Document (PDF) (105 KB PDF).

April 01, 1987. Memorandum. 5 Page(s).
Richard Levy. Toxicology Branch.
Propazine: Qualitative Risk Assessment of Two-Year Chronic Oral Study in Female
Rats (IRDC Report No. 382- 007; April 28, 1980). Caswell # 184.
Document (PDF) (224 KB PDF).

June 12, 1987. Memorandum. 2 Page(s).
C. J. Nelson. Toxicology Branch.
Propazine: Qualitative Risk Assessment of Two-Year Chronic Oral Study in Female
Rats (IRDC Report No. 382- 007; April 28, 1980). Caswell # 184. Tox review 006504.
Document (PDF) (90 KB PDF).

June 17, 1987. Memorandum. 7 Page(s).
Charles Frick. Residue Chemistry Branch.
Addendum to Residue Chemistry Chapter for Propazine Registration Standard:
Tolerance Assessment System Tolerance Reassessment.
Document (PDF) (303 KB PDF).

June 23, 1987. Memorandum. 11 Page(s).
William Dykstra. Toxicology Branch.
Cover Memorandum for Propazine Registration Standard Tox review 005823.
Document (PDF) (598 KB PDF).

January 13, 1988. Review. 9 Pages.
Michael Firestone. Exposure Assessment Branch.
Propazine. Submission Purpose: Exposure Assessment for Policy Group.
Document (PDF) (217 KB PDF).

January 29, 1988. Memorandum. 48 Pages.
William Dykstra. Toxicology Branch.
Propazine Registration Standard - Calculation of Worker Risks Based on EAB
Exposure Assessment for Policy Group. Caswell No.: 184. TXR No.: 006566.
Document (PDF) (1225 KB PDF).

May 31, 1988. Review. 1 Page.
Tyrone Aiken. Product Chemistry Branch.
Chemistry Review by Tyrone Aiken. EPA File Symbol: 45115-10. Product ingredient
source information and inert ingredient information are deleted.
Document (PDF) (82 KB PDF).

August 30, 1988. Memorandum. 7 Page(s).
C. J. Nelson. Toxicology Branch.
PROPAZINE - Updated Qualitative Risk Assessment from a Rat 2-Year Chronic
Oncogenicity Study Tox review 006954.
Document (PDF) (239 KB PDF).

November 16, 1988. Memorandum. 25 Pages.
Esther Rinde. Health Effects Division.
Peer review on Propazine.
Document (PDF) (632 KB PDF).

November 17, 1988. Memorandum. 7 Page(s).
C. J. Nelson. Toxicology Branch.
PROPAZINE - Second Updated Qualitative Risk Assessment from a Rat 2-Year
Chronic Oncogenicity Study Tox review 006946.
Document (PDF) (299 KB PDF).

November 19, 1988. Memorandum. 20 Pages.
William Dykstra. Toxicology Branch I.
Propazine; Evaluation of Mammary Tumors in Female Rats. Tox. Chem. No. 184.
Document (PDF) (428 KB PDF).

January 10, 1989. Memorandum. 17 Page(s).
Esther Rinde. Science Analysis & Coordination Branch.
Peer Review of Propazine - Re-Evaluation (2nd).
Document (PDF) (724 KB PDF).

October 01, 1990. Review. 3 Page(s).
Toxicology Branch.
Reference Dose for Chronic Oral Exposure (RfD) for Propazine.
Document (PDF) (214 KB PDF).

January 07, 1991. Memorandum. 17 Pages.
Joseph A. Cotruvo. Health and Environmental Review Division.
Structure-Activity Relationship (SAR) Analysis of s-Triazine
Pesticides and Related Compounds.
Document (PDF) (580 KB PDF).

January 07, 1991. Memorandum. 5 Pages.
Henry Spencer. Toxicology Branch I.
Conclusions Drawn from Structure-Activity-Relationship (SAR) Analysis of
s-Triazine Pesticides and Related compounds from OTS.
Document (PDF) (190 KB PDF).

February 14, 1991. Memorandum. 4 Pages.
Jerome Blondell. Occupational & Residential Exposure Branch.
Review of midwest cancer epidemiology studies related to triazines.
HED Project No. INTRA-0141.
Document (PDF) (191 KB PDF).

August 09, 1993. Oneliner. 6 Page(s).
Environmental Fate and Ground Water Branch..
Pesticide Environmental Fate One Line Summary Propazine.
Document (PDF) (295 KB PDF).

December 17, 1993. Summary. 2 Pages.
OPP. EPA.
Summary of the Environmental Toxicity of Propazine (12/17/93).
Document (PDF) (257 KB PDF).

January 01, 1994. DER. 15 Pages.
Rodolfo A. Pisigan. ERB-IV.
DATA EVALUATION RECORD. STUDY ID 441848-05. Solution Photolysis of
[14C] Propazine in Artificial Light. Laboratory Project Identification: PTRL
Project No. : 851. Pages 6-15 removed, registrant data.
Document (PDF) (304 KB PDF).

January 01, 1994. DER. 15 Pages.
Rodolfo A. Pisigan. ERB-IV.
DATA EVALUATION RECORD. STUDY ID 441848-06. Soil Surface Photolysis
of [14C] propazine in Artificial Light. Laboratory Project Identification: PTRL
Project No. : 852. Pages 6-15 removed, registrant data.
Document (PDF) (301 KB PDF).

March 24, 1994. Memorandum. 4 Pages.
G. Jeffrey Herndon. Chemistry Branch I.
Propazine (PC Code: 80808, CAS#: 139-40-2). Review of the Proposed Protocols for Conducting
the Following Studies Using 14C-Labeled Propazine: Nature of the Residue in Sorghum, Nature
of the Residue in Lactating Goats,…(DP Barcode# D196214, CBTS# 12729).
Document (PDF) (46 KB PDF).

January 01, 1995. DER. 13 Pages.
Rodolfo A. Pisigan. ERB-IV.
DATA EVALUATION RECORD. MRID 441848-07. Aerobic Soil Metabolism of
[14C] Propazine in Sandy Loam. Laboratory Project Identification: PTRL Project No. 865.
Pages 6-13 removed, registrant data.
Document (PDF) (287 KB PDF).

February 09, 1995. Memorandum. 5 Pages.
William Dykstra. Toxicology Branch I.
Propazine; Request for Waiver of Chronic Dog Feeding Study (Guideline
Requirement 83-1(b); ID #: 285929; Griffin Corporation. Tox.Chem No. : 184. MRID No. : None.
DP Barcode No. : 206649. Submission No. : 471963.
Document (PDF) (173 KB PDF).

April 27, 1995. Memorandum. 2 Pages.
William Dykstra. Toxicology Branch I.
Propazine Technical; Waiver Request of 90-Day Dog Feeding Study with Propazine;
001812-GAG; P.C. Code 080808; Griffin Corporation. Tox.Chem No. : 184.
DP Barcode No. : D213630. Submission No. : S484401. TXR No. 011523.
Document (PDF) (65 KB PDF).

August 22, 1995. Review. 1 Page.
Sami Malak. Registration Support Branch.
PRODUCT CHEMISTRY REVIEW OF MP [ ] EP [ ] TECHNICAL [X] DP BARCODE No. : 218372
REG. /File Symbol No. : 1812-GAG. PRODUCT NAME: 080808 Propazine Technical,
CAS #139-40-2. APPLICANT: 001812 Griffin corporation. RECEIVED: 08/02/95.
Document (PDF) (60 KB PDF).

September 18, 1995. Review. 5 Pages.
Sami Malak. Registration Support Branch.
PRODUCT CHEMISTRY REVIEW OF MP [] EP [X]. DP BARCODE No. : 219082
REG. /File Symbol No. : 1812-GLE. PRODUCT NAME: Milo-Pro 4L, 43% Propazine,
CAS #139-40-2. APPLICANT: 001812 Griffin Corporation RECEIVED: 09/18/95.
Document (PDF) (262 KB PDF).

September 26, 1995. Review. 13 Pages.
Sami Malak. OPP/EPA.
DP BARCODE: D219079 SUBMISSION: S493480 REG/FILE SYMBOL No. :1812-GAG.
COMMON NAME: Propazine CAS Registry No. : 139-40-2. MRID #: 435101-03 to 435101-09 & 435129-01.
Manufacturing process, product impurities & QCP deleted from pages 8-13 deleted.
Document (PDF) (954 KB PDF).

October 23, 1995. DER. 14 Pages.
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Study 3. STUDY ID 436898-04. Soil Adsorption/Desorption [14C] Propazine by the
Batch Equilibrium Method. Project No. 853. Report No. 1653.
Document (PDF) (1085 KB PDF).

October 23, 1995. DER. 17 Pages.
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Study 2. STUDY ID 436898-03. Column Leaching of [14C] Propazine in Four Soil
Types Following Aerobic Aging. Project 855. Report No. 1660.
Document (PDF) (1242 KB PDF).

October 23, 1995. DER. 9 Pages.
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Study 1. STUDY ID 436898-02. Hydrolysis of [14C] Propazine in Aqueous Buffered
Solutions at pH 5, 7 and 9. Project No. 850. Report No. 1640.
Document (PDF) (731 KB PDF).

October 27, 1995. Memorandum. 16 Pages.
Nelson Thurman. Environmental Fate & Ground Water Branch.
Propazine New Chemical Review for Non-Food Greenhouse Uses, Environmental
Fate Data sponsored by Griffin Corporation. Barcode(s): D219081.
MRID Nos. 436898-02, 436898-03, 436898-04, 001537-12.
Document (PDF) (1199 KB PDF).

December 08, 1995. Review. 2 Pages.
Sami Malak. Registration Support Branch.
DP BARCODE: D221337. SUBMISSION: S497633. REG/FILE SYMBOL No. : 1812-GAG.
CHEMICAL NAME: 080808 2-Chloro-4,6-bis(isopropylamino-s-triazine COMMON NAME: Propazine
CAS Registry No. : 139-40-2. DATA SUBMITTER: 001812 Griffin Corporation. MRID #: 438405-01.
Document (PDF) (306 KB PDF).

January 01, 1996. DER. 10 Pages.
Rodolfo A. Pisigan. ERB-IV.
DATA EVALUATION RECORD CHEM 080808 Propazine §164-1. STUDY ID 441848-08.
The Mobility and Degradation of 14C-Propazine Utilizing Field Installed
Lysimeters in a North Carolina Loamy Sand Soil. Pages 5-6, 9 deleted, registration data.
Document (PDF) (731 KB PDF).

January 01, 1996. DER. 32 Pages.
Rodolfo A. Pisigan. OPPTS/OPP/EFED CRS #.
DATA EVALUATION RECORD. STUDY ID 441848-09. Field Soil Dissipation of
Propazine (Milo -Pro TM 4L) on Bare Soil in Texas. Laboratory Project
Identification: CHW Study No. 6641-100. Pages 7-32 removed, registrant data.
Document (PDF) (422 KB PDF).

January 11, 1996. Memorandum. 3 Pages.
Michael S. Metzger. Chemistry Branch I.
Propazine. Response to Meeting (8/2/95). Memorandum of Understanding Submitted by Griffin.
Document (PDF) (125 KB PDF).

March 07, 1996. Memorandum. 35 Pages.
Kathryn Boyle. Risk Characterization & Analysis Branch.
Review of Human Health Assessment of Propazine, PC Code 080808, D22149, D224185.
Document (PDF) (1386 KB PDF).

March 07, 1996. Review. 4 pages.
John Abbotts. Chemistry Branch II.
Propazine (080808), Reregistration Case No. 0230. Conversations with Registrant
Representative. No CBRS No. , No DP Barcode No. , No MRID No.
Document (PDF) (180 KB PDF).

April 12, 1996. DER. 16 Pages.
Marion Copley. Toxicology Branch I.
DATA EVALUATION REPORT Propazine STUDY TYPE: Metabolism Study - Rat (85-1).
Metabolism - Rat OPPTS 870.7485 [§85-1)]. DP Barcode No. D219174.
SUBMISSION CODE: S493480. TOX. CHEM. No. : 184.
Document (PDF) (568 KB PDF).

April 18, 1996. Memorandum. 4 Pages.
Nelson Thurman. Environmental Fate & Ground Water Branch.
Propazine: Comments on Griffin Corporation Response to EPA's Grassely-Allen
Notification, Dated September 27, 1995. DP Barcode: D224521.
Document (PDF) (518 KB PDF).

May 14, 1996. Review. 10 Pages.
John Abbotts. Chemistry Branch II.
Propazine (080808), Reregistration Case No. 0230. Registrant Griffin Corporation.
Dietary and Drinking Water Health Hazard Assessment. CBRS No. 16780, DP Barcode No. D222623
(SRRD); CBRS No. 17099, DP Barcode No. D224749 (RD); No MRID No.
Document (PDF) (434 KB PDF).

May 20, 1996. Memorandum. 3 Pages.
Jim Carleton. OPP/EPA.
Review of handler exposure assessment submitted in response to the Propazine
Grassley-Allen letter. DP Barcode: D222622, D224748.
Document (PDF) (131 KB PDF).

May 28, 1996. Review. 4 Pages.
John Abbotts. Chemistry Branch II.
Propazine (080808), Proposed New Use on Sorghum.
Registrant Griffin Corporation. Residue Chemistry Requirements. CBRS No. 17214,
DP Barcode Nos. D226108 (RD), D226191 (RCAB); No MRID.
Document (PDF) (139 KB PDF).

July 02, 1996. Memorandum. 19 Pages.
Kit Farwell. Toxicology Branch I.
PROPAZINE; Required Studies for Non-food Greenhouse Use by Griffin Corporation.
Barcode No. : D227218. Submission No. : S493480. Tox Chem No. : 184.
Document (PDF) (684 KB PDF).

July 29, 1996. Memorandum. 59 Pages.
Kit Farwell. Toxicology Branch I.
Executive Summary for 1980 Propazine Carcinogenicity study in Mice (MRID 00044335).
DP Barcode: D228305 f.s. PC Code: 080808 Tox Chem No. : 184.
Document (PDF) (1733 KB PDF).

August 06, 1996. Package. 146 Pages.
Health Effects Division..
HIARC Briefing Packages. Executive Summary for 1980 Propazine Carcinogenicity study
in Mice (MRID 00044335). DP Barcode: D228305 f.s. PC Code: 080808. Tox Chem No. : 184.
Document (PDF) (4929 KB PDF).

August 07, 1996. Memorandum. 3 Pages.
Kathryn Boyle. Risk Characterization & Analysis Branch.
Review of Human Health Assessment of Propazine, PC Code 080808, D22149, D224185.
Document (PDF) (138 KB PDF).

August 08, 1996. Memorandum. 14 Pages.
Esther Rinde. Health Effects Division.
Carcinogenicity Peer Review Meeting on Propazine.
Document (PDF) (428 KB PDF).

August 21, 1996. Review. 1 Page.
Shyam Mathur. Registration Support Branch.
PRODUCT CHEMISTRY REVIEW OF MP [] EP [X]. DP BARCODE No. : D226094 REG. /File
Symbol No.: 1812-GAG. PRODUCT NAME: Propazine Technical. COMPANY: Griffin Corporation.
Document (PDF) (517 KB PDF).

August 26, 1996. Memorandum. 3 Pages.
Lori Brunsman. Science Analysis Branch.
REVISED Propazine Qualitative Risk Assessment Based On 1995 Re-Read of
Female Mammary Gland Slides From 1981 Sprague-Dawley Rat Dietary study.
TXR No. 012817. (MRID No. 00414-08).
Document (PDF) (132 KB PDF).

October 07, 1996. Review. 12 Pages.
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Common Name: Propazine. Trade name: Milo-Pro. Company name: Griffin Corporation.
ID #: 080808. Purpose: Should the propazine be included in the triazine special review?.
Action Code: 116. DP Barcode: D224353.
Document (PDF) (1510 KB PDF).

November 15, 1996. Memorandum. 5 Pages.
Norman Cook. Ecological Effects Branch.
Comments RE: Griffin Chemical Co. Response to EPA Grassley-Allen Letter to
Special Review Propazine Herbicide Uses On Sorghum and "Greenhouse" Uses.
DP barcodes: D224520, D224187.
Document (PDF) (362 KB PDF).

January 21, 1997. Memorandum. 46 Pages.
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Review of surface water exposure portions of Griffin Corporation's response
to the propazine Grassley-Allen letter and a supporting study (D224188).
Document (PDF) (4337 KB PDF).

February 28, 1997. Memorandum. 2 Page(s).
Bernice Fisher. Toxicology Branch.
Propazine, Quantitative Risk Assessment - Revised Q1*,
(3/4's Interspecies Scaling Factor), Two-Year Sprague-Dawley Rat Dietary Study.
Document (PDF) (104 KB PDF).

May 07, 1997. Review. 26 Pages.
William B. Greear. Toxicology Branch I.
PROPAZINE - Submission of a 21-Day Dermal Study in Rats and a Developmental
Toxicity Study In Rabbits for Review (EPA ID 001812-GAG). TOX Chern No.: 184.
DP Barcode: D232468, D232469. Submission No. : S514322. TXR No. 012214.
MRID Nos. 44127401, 44153401.
Document (PDF) (869 KB PDF).

May 08, 1997. Memorandum. 16 Page(s).
William Dykstra. Toxicology Branch.
Carcinogenicity Peer Review of Propazine (3rd).
Document (PDF) (890 KB PDF).

August 01, 1997. Memorandum. 30 Pages.
Kit Farwell. Reregistration Branch 1, HED.
Reviews of 6 Acute Studies with Milo-Pro 4L Herbicide (43,9% Propazine).
DP Barcode: D219175. Submission: S493489. Tox Chem No: 184. TXR No. 014091.
MRID Nos. 43474107, 43474108, 43474109, 43474110, 43474111, 43474112.
Document (PDF) (853 KB PDF).

August 01, 1997. Memorandum. 49 Pages.
Kit Farwell. Reregistration Branch 1, HED.
Reviews of Metabolism Study with Technical Propazine and Battery of 6 Acute Studies with
Technical Propazine. DP Barcode: D219174. Submission: S493480. PC Code: 080808. Tox Chem No: 184.
TXR No. 012286. MRID Nos. 43474101 thru 43474106, 43689801.
Document (PDF) (1566 KB PDF).

August 21, 1997. Memorandum. 14 Pages.
George Z. Ghali. Health Effects Division.
Propazine: Hazard Identification Committee Report. CASRN: 139-40-2. PC Code: 080808.
Caswell: 184. TXR No. 012411.
Document (PDF) (479 KB PDF).

October 01, 1997. Memorandum. 3 Pages.
Jack Arthur. Exposure SAC.
Exposure SAC Review of Propazine.
Document (PDF) (88 KB PDF).

October 08, 1997. DER. 5 Pages.
Nicholas E. Federoff. ERB IV.
DATA EVALUATION RECORD ALGAE OR DIATOM EC50 TEST GUIDELINE 122-2 OR 123-2 (TIER I OR II).
Acute toxicity of propazipe to Navicula pelliculosa. DP Barcode: D237791. MRID No. : 442873-10.
Document (PDF) (535 KB PDF).

October 08, 1997. DER. 6 Pages.
Nicholas E. Federoff. ERB IV.
DATA EVALUATION RECORD. EC50 TEST WITH LEMNA GIBBA.
GUIDELINE 122-2 OR 123-2 (TIER I OR II). 14-Day static toxicity of propazine to
Lemna gibba G3. DP Barcode: D237791. MRID No. : 442873-09.
Document (PDF) (566 KB PDF).

October 09, 1997. DER. 5 Pages.
Nicholas E. Federoff. ERB IV.
DATA EVALUATION RECORD ALGAE OR DIATOM EC50 TEST GUIDELINE 122-2 OR 123-2
(TIER I OR II). Acute toxicity of propazine to Selenastrum capricornutum Printz.
DP Barcode: D237791. MRID NO. : 442873-08.
Document (PDF) (526 KB PDF).

October 09, 1997. DER. 5 Pages.
Nicholas E. Federoff. ERB IV.
DATA EVALUATION RECORD. ALGAE OR DIATOM EC50 TEST GUIDELINE 122-2 OR 123-2.
(TIER I OR II). Acute toxicity of propazine to Anabaena flos-aquae.
DP Barcode: D237791. MRID No. : 442873-12.
Document (PDF) (526 KB PDF).

November 14, 1997. Memorandum. 13 Page(s).
Kit Farwell. Reregistration Branch 1, HED.
Executive Summaries for Subchronic Dog Toxicity Study, Chronic/Carcinogenicity
Study in Rats, Developmental Rat and Rabbit Toxicity Studies, and Reproductive
Toxicity Study in Rats with Propazine. Tox review 012391.
MRID 111680,41408,150242,44153401,41409.
Document (PDF) (697 KB PDF).

November 17, 1997. Memorandum. 17 Pages.
Kit Farwell. Reregistration Branch 1, HED.
Propazine. DCI for Chronic 52-Week Toxicity Study in Dogs (83-1b) and Mutagenicity
Study in Germ Cells (842); Additional Data Required for Metabolism Study (MRID 43689801).
DP Barcode: D240126. PC Code: 080808 Submission: N/A. Tox Chem No. : 184.
Document (PDF) (611 KB PDF).

February 27, 1998. Memorandum. 5 Pages.
Rudy A. Pisigan. Environmental Risk Branh IV.
Tier I Estimated Environmental Concentrations for Propazine on Grain Sorghum.
DP Barcode: D242425.
Document (PDF) (613 KB PDF).

April 16, 1998. DER. 23 Pages.
Rodolfo A. Pisigan. ERB-IV.
Study ID 442873-13. Soil Adsorption/Desorption of 2-Hydroxy-[14C]Propazine by the
Batch Equilibrium Method. Project No. 913. Report No. 1817.
Document (PDF) (1447 KB PDF).

April 16, 1998. DER. 30 Pages.
Rodolfo A. Pisigan. ERB-IV.
Study ID 442873-14. Field Soil Dissipation of Propazine (Milo-Pro™ 4L) on Bare Soil
in North Carolina. Laboratory Project identification: CHW Study No. 6641-100A.
Document (PDF) (2230 KB PDF).

April 16, 1998. Memorandum. 12 Pages.
Rudy A. Pisigan. Environmental Risk Branh IV.
Tier II Modeling of Surface Water EECs for Propazine Use on Grain
Sorghum and Comparison of Model Output with Monitoring Data
(PC Code: 080808; DP Barcode: D242425; not EPA registered).
Document (PDF) (1191 KB PDF).

October 07, 1998. DER. 5 Pages.
Nicholas E. Federoff. ERB IV.
Data Evaluation Record ALGAE OR DIATOM EC50 TEST GUIDELINE 122-2 OR 123-2
(TIER I OR II). Acute toxicity of propazine to Skeletonema costatum.
DP Barcode: D237791. MRID No. : 442873-11.
Document (PDF) (532 KB PDF).

October 15, 1998. DER. 6 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 71-1 (A) - AVIAN SINGLE-DOSE LD50 TEST. Acute oral toxicity of
propazine to bobwhite quail (Colinus virginianus). DP Barccde: D237791. MRID No.: 442873-01.
Document (PDF) (509 KB PDF).

October 15, 1998. DER. 6 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 71-2 (A) -- UPLAND GAME BIRD DIETARY LC50 TEST.
Acute dietary toxicity of propazine to bobwhite quail (Colinus virginianus).
DP Barcode: D237791. MRID No. : 442873-02.
Document (PDF) (635 KB PDF).

October 15, 1998. DER. 6 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record Freshwater Fish Early Life-Stage Test Guideline 72-4 (A).
Analytical analysis of propazine during the early life-stage toxicity test with
the sheepshead minnow (Cyprinodon variegatus). MRID No.: 443276-01.
Document (PDF) (606 KB PDF).

October 15, 1998. DER. 7 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 71-2 (B) -- WATERFOWL DIETARY LC50 TEST.
Acute dietary toxicity of propazine to mallard ducks (Anas platyrhynchos).
DP Barcode: D237791. MRID No. : 442873-03.
Document (PDF) (698 KB PDF).

October 15, 1998. DER. 8 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 72-2 -- ACUTE LC50 TEST WITH A FRESHWATER INVERTEBRATE.
Acute toxicity of propazine to Daphnia magna. MRID No. : 442873-05. DP Barcode: D237791.
Document (PDF) (752 KB PDF).

October 15, 1998. DER. 8 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 72-3(B) -- Acute EC50 Test With an Estuarine/Marine Mollusk Shell
Deposition Study. Flow through shell deposition tests with propazine and the eastern oyster.
DP Barcode: D237791. MRID No. : 442873-06.
Document (PDF) (686 KB PDF).

October 15, 1998. DER. 9 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record § 72 -1 (A) -- ACUTE LC50 TEST WITH A WARMWATER FISH.
Acute toxicity of Propazine to bluegill. DP Barcode: D237791. MRID No. : 442873-04.
Document (PDF) (853 KB PDF).

October 15, 1998. DER. 9 Pages.
Ann Stavola. ERB IV.
Data Evaluation Record FRESHWATER FISH EARLY LIFE-STAGE TEST GUIDELINE 72-4 (A).
Early life-stage toxicity of propazine to the fathead minnow (Pimephales promelas)
under flow-through conditions. MRID No. : 442873-07.
Document (PDF) (909 KB PDF).

October 15, 1998. DER. 9 Pages.
Nicholas E. Federoff. ERB IV.
Data Evaluation Record AQUATIC INVERTEBRATE LI FE CYCLE TEST GUIDELINE. 72-4 (B).
MRID No. 44 3276-02. DP Barcode No. D237791.
Document (PDF) (1756 KB PDF).

October 15, 1998. Memorandum. 2 Pages.
Thomas Steeger. Environmental Risk Branch IV.
Ecological effects associated with the use of Propazine (MILO-PRO 4L Herbicide)
on grain sorghum to control weeds. DP Barcode: D237791.
MRID Nos. : 442873-01 thru -12, 443276-01, -02.
Document (PDF) (957 KB PDF).

March 02, 1999. Memorandum. 6 Pages.
Rudy A. Pisigan. Environmental Risk Branh IV.
Tier I Estimated Environmental Concentrations for Propazine (MiloPro 4L)
on Grain Sorghum. DP Barcode: D249788.
Document (PDF) (659 KB PDF).

October 09, 2003. Review. 1 Page.
Shyam Mathur. Technical Review Branch.
PRODUCT CHEMISTRY REVIEW OF TGAI/MP[X] EP [ ]. DP BARCODE No.: D290163
REG. No.: 1812-363. PRODUCT NAME: Propazine Technical. COMPANY: Griffin LLC.
PCC: 080808; Decision No. : 172762 ; FOOD USE [].
Document (PDF) (432 KB PDF).

October 09, 2003. Review. 3 Pages.
Shyam Mathur. Technical Review Branch.
PRODUCT CHEMISTRY REVIEW OF TGAI/MP[X] EP [ ]. DP BARCODE No.: D290163
REG. No.: 1812-363. PRODUCT NAME: Propazine Technical. COMPANY: Griffin LLC.
PCC: 080808; Decision No. : 172762; FOOD USE [].
Inert ingredient info. on pages 2-3 deleted.
Document (PDF) (36 KB PDF).

June 26, 2004. Review. 2 Pages.
Indira Gairola. Technical Review Branch.
DP BARCODE: D298801. EPA REG. No. : 1812-352. PRODUCT NAME: PROPAZINE 4L.
Decision No. 338648. PC Codes 080808. FOOD USE [ ]. COMPANY: GRIFFIN L.L.C.
Document (PDF) (42 KB PDF).

August 25, 2004. Memorandum. 5 Pages.
William Phillips. Biological Analysis Branch.
Atrazine/Propazine Use on Sorghum.
Document (PDF) (279 KB PDF).

January 11, 2005. Memorandum. 4 Pages.
Tim Kiely & Steve Smearman. Biological and Economic Analysis Division.
Projected Percent of Crop Treated Estimates for Propazine on Sorghum.
Document (PDF) (163 KB PDF).

August 22, 2005. Memorandum. 3 Pages.
Monica S. Hawkins. Chemistry and Exposure Branch.
Review of Propazine Incident Reports. DP Barcode D308532, Chemical 080808.
Document (PDF) (138 KB PDF).

August 23, 2005. Review. 2 Pages.
Sami Malak. Technical Review Branch.
PRODUCT CHEMISTRY REVIEW OF: AN End-Use Product [X] DP BARCODE #: D320359
EPA RECEIVED DATE: 11/AUG/2005 REG No. : 19713-553 PRODUCT NAME: Drexel Simazine 90DF
MRID: 466098-01 FOOD USE [X] COMPANY NAME : Drexel Chemical Company. ACTION CODE: 570.
Document (PDF) (30 KB PDF).

August 30, 2005. DER. 14 Pages.
Anita Pease. ERB III.
Data Evaluation Record Acute LC50 Test with an Estuarine/Marine Organism §72-3(C)-Shrimp.
Static Acute Toxicity of Propazine To The Mysid (Mysidopsis bahia).
MRID No. : 441848-01. DP Barcode: D237791.
Document (PDF) (116 KB PDF).

August 30, 2005. Review. 18 Pages.
Thuy L. Nguyen. Environmental Risk Branch III.
Aquatic Exposure Assessment. Drinking Water Assessment for Propazine Use on
Sorghum and Green House Ornamentals. DP Barcode: DP 321142.
Document (PDF) (1361 KB PDF).

August 31, 2005. DER. 38 Pages.
Anita Pease. ERB III.
DATA EVALUATION RECORD AQUATIC INVERTEBRATE LIFE CYCLE
TEST § 72-4(c). Chronic Toxicity of Propazine To The Mysid, Mysidopsis bahia.
MRID No. : 441848-03. DP Barcode: D237791.
Document (PDF) (211 KB PDF).

August 31, 2005. Memorandum. 24 Pages.
Jose J. Morales. Reregistration Branch 3.
Propazine. Acute and Chronic Dietary Exposure Assessment for the Reregistration
Eligibility Decision which includes a New Use on Sorghum. DP Barcode: DP308534.
Document (PDF) (903 KB PDF).

August 31, 2005. Memorandum. 35 Pages.
Steven Weiss. Reregistration Branch 3 HED.
PROPAZINE: Occupational and Residential Exposure Assessments for the
Proposed Sorghum Use and the Existing Greenhouse Uses Updated with New
Toxicity Endpoints. DP Barcode: D308535.
Document (PDF) (2042 KB PDF).

August 31, 2005. Memorandum. 53 Pages.
Jose J. Morales. Reregistration Branch 3.
Propazine. Residue Chemistry Summary for the Tolerance Reassessment Eligibility
Decision Document (TRED) and a Proposal To Reinstate Food/Feed Use on Grain
Sorghum (PP#7F4837). DP Number: D308537.
Document (PDF) (2732 KB PDF).

August 31, 2005. Memorandum. 55 Pages.
Jose Morales et al. Reregistration Branch 3.
Propazine: Preliminary HED Risk Assessment for the Tolerance Reassessment
Eligibility Decision Document (TRED) which includes a New Use on Sorghum.
PC Code: 080808, DP Barcode: D308533.
Document (PDF) (3179 KB PDF).

August 31, 2005. Memorandum. 7 Pages.
Jose J. Morales. Reregistration Branch 3.
Propazine TRED - Report on the FQPA Tolerance Reassessment Progress and Interim Risk
Management Decisions. Product Chemistry Considerations. Case 0230. DP Barcode: D308536.
Document (PDF) (272 KB PDF).

September 21, 2005. Memorandum. 2 Pages.
David Soderberg et al. Reregistration Branch 3.
Propazine: Amendment to HED Human Health Risk Assessment (dated May 31, 2005).
Corrections to Appendix 1.0. PC Code: 080808, Case #: 0230, DP Barcode: 321770.
Document (PDF) (95 KB PDF).

October 11, 2005. Memorandum. 5 Pages.
William Phillips. Biological Analysis Branch.
Atrazine and Propazine Use Rates in Sorghum for Potential Co-occurrence (DP 308550).
Document (PDF) (202 KB PDF).

December 06, 2005. Memorandum. 2 Pages.
Lisa Austin. Registration Action Branch 1.
PROPAZINE - Review of In vivo Mammalian Spermatogonial Chromosome
Aberration Test-mouse (MRID 46171701). TXR#: 0052927. DP Barcode Nos: D310325.
Document (PDF) (17 KB PDF).

December 09, 2005. Memorandum. 196 Pages.
Jose J. Morales. Reregistration Branch 3.
Propazine. Revised Residue Chemistry Summary for the Tolerance Reassessment Eligibility
Decision Document (TRED) and a Proposal To Reinstate Food/Feed Use on Gram Sorghum (PP#7F4837).
DP Barcode No: 323273. MRID No. 44287315-16, 44184810 thru 17.
Document (PDF) (5817 KB PDF).

December 13, 2005. Memorandum. 55 Pages.
Jose Morales & John Liccione & Steve Weiss. Reregistration Branch 3.
Propazine: Revised HED Risk Assessment for the Tolerance Reassessment
Eligibility Decision Document (TRED) which includes a New Use on Grain
Sorghum. PC Code: 080808, DP Barcode: D323271.
Document (PDF) (306 KB PDF).

February 26, 2006. DER. 18 Pages.
Anita Pease. ERB II.
Data Evaluation Report on the Toxicity of Propazine to Sheepshead Minnow,
Early Life Cycle. MRID No. 441848-02. DP Barcode D237791.
Document (PDF) (130 KB PDF).

February 26, 2006. DER. 62 Pages.
John Marton. Cambridge Environmental Inc.
Data Evaluation Report on the Acute Toxicity of Propazine to Terrestrial
Vascular Plants: Vegetative Vigor. MRID No. 441848-04. DP Barcode: D237791.
Document (PDF) (216 KB PDF).

February 26, 2006. DER. 83 Pages.
John Marton. Cambridge Environmental Inc.
Data Evaluation Report on the Acute Toxicity of Propazine to Terrestrial
Vascular Plants: Seedling Emergence. MRID No. 441848-04. DP Barcode: D237791.
Document (PDF) (257 KB PDF).

March 28, 2006. Memorandum. 65 Pages.
Jose Morales et al. Reregistration Branch 3.
Triazine Cumulative Risk Assessment. HED Human Health Risk Assessment In Support of
the Reregistration Eligibility Decisions for Atrazine, Simazine and Propazine.
PC Codes: 080808, 080803, 080807. DP 317976.
Document (PDF) (2715 KB PDF).

November 03, 2006. Eco. Risk Assessment. 134 Pages.
Pamela M. Hurley. Ecological Risk Branch III.
Ecological Risk Assessment Section 3 (New Use on Sorghum)
Propazine (PC Code 080808, CASN 139-40-2).
Document (PDF) (9278 KB PDF).

November 03, 2006. Memorandum. 4 Pages.
Pamela Hurley. Environmental Risk Branch 3.
Transmittal of the Environmental Fate and Effects Division's (EFED) Registration
Science Chapter for the Ecological Risk Assessment of Propazine New Use on Sorghum.
DP Barcodes: D310326, D249944, D249945.
Document (PDF) (358 KB PDF).

December 04, 2006. Memorandum. 12 Pages.
Mark Corbin. Environmental Fate & Ground Water Branch.
Addendum to the Environmental Fate and Effects Division (EFED) Drinking Water
Exposure Assessent for the Addition of Propazine Use on Sorghum to the Triazine
Cumulative Dietary Risk Assessment.
Document (PDF) (838 KB PDF).

December 11, 2006. Memorandum. 12 Pages.
Mark Corbin. Environmental Fate & Ground Water Branch.
Addendum to the Environmental Fate and Effects Division (EFED) Drinking Water
Exposure Assessment for the Addition of Propazine Use on Sorghum to the Triazine
Cumulative Dietary Risk Assessment (DP 334595).
Document (PDF) (734 KB PDF).

March 09, 2007. Memorandum. 4 Pages.
Jihad Alsadek. Science Information and Analysis Branch.
Refined Projected Percent Crop Treated (PPCT) Estimates for Use of Propazine
and Atrazine on Sorghum in Texas, PC Code 080808, DP Barcode 335065.
Document (PDF) (226 KB PDF).

March 13, 2007. Memorandum. 5 Pages.
Mark Corbin. Environmental Fate & Ground Water Branch.
Addendum to the Environmental Fate and Effects Division (EFED) Drinking Water
Exposure Assessment for the Addition of Propazine Use on Texas Sorghum to the
Triazine Cumulative Dietary Risk Assessment (DP 336742 & DP 329876).
Document (PDF) (403 KB PDF).

June 26, 2007. Review. 8 Pages.
Sayed Tadayon. Chemistry Exposure Branch HED.
Triazine Cumulative Risk Assessment for the Proposed Use of Propazine
on Grain Sorghum. DP Barcode 336673.
Document (PDF) (408 KB PDF).

December 01, 2007. DER. 15 Pages.
P. Liccione. Registration Action Branch 3.
DATA EVALUATION RECORD PROPAZINE CHRONIC ORAL TOXICITY: DOG
[OPPTS 870.4100b (§83-1b)] MRID 46654401. TXR#: 0053788. DP BARCODE: D322219.
Document (PDF) (428 KB PDF).

June 16, 2008. Memorandum. 7 Pages.
Pamela Hurley. Environmental Risk Branch 3.
Transmittal of the Environmental Fate and Effects Division's (EFED) Response to Comments
on Data Gaps Identified in the Registration Science Chapter for the Ecological Risk
Assessment of Propazine New Use on Sorghum (DP 310326) dated November 2, 2006.
Document (PDF) (595 KB PDF).

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