PPDC 21st Century Toxicology/New Integrated Testing Strategies Workgroup Archive

2011
2010
2009
2008

To read the summary of each meeting, follow the link provided on the meeting date. For more information contact Rebecca von dem Hagen (vondem-hagen.rebecca@epa.gov).

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2011 Meeting Minutes

November 2, 2011 - The key discussion topics included a debrief of the October 11, 2011 Stakeholder Workshop, a discussion on recommendations to move forward, and ideas for other 1-day FACAs.

October 11, 2011 - Stakeholder Workshop on “Diagnostic Tools and Biomarkers in Pesticide Medical Management, Exposure Surveillance, and Epidemiologic Research.”

September 15, 2011 (PDF) (1 pg, 28K) - The key discussion topics included the introduction of a new workgroup member and preparation for the October 11, 2011 Stakeholder Workshop.

July 20, 2011 (PDF) (1 pg, 25.93K) - The key discussion topics included the October 11, 2011 Stakeholder Workshop and the creation of a subcommittee to develop outreach options for the Workgroup.

May 12, 2011 (PDF) (1 pg, 34.93K) - The key discussion topics included the introduction of two new members, the SAP Consultation in May 2011, and the October 11, 2011 Stakeholder Workshop.

March 23, 2011 (PDF) (2 pp, 33.57K) - The discussion topics included the December 13, 2010 Stakeholder Workshop, the upcoming April 2011 PPDC Meeting, the SAP Consultation in May 2011, and the October 2011 Stakeholder Workshop on “Diagnostic Tools and Biomarkers in Pesticide Medical Management, Exposure Surveillance, and Epidemiologic Research.”

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2010

December 13, 2010 - Workshop on 21st Century Science and Integrated Testing and Assessment Strategies: Transitioning Research to Regulatory Practice.

Agenda (PDF) (2 pp, 40.50K)
Webcast Instructions (PDF) (2 pp, 31.01K)
Workshop Summary (PDF) (5 pp, 68.83K)
Transitioning Research to Regulatory Practice (PDF) (1 pg, 202K)
A Strategic Vision for a 21st Century Testing & Assessment Paradigm (PDF) (22 pp, 399K)
Communication of Science Policy (PDF) (13 pp, 1.40MB)
Using Searchable Databases and Predictive Systems: MetaPath (PDF) (16 pp, 210K)
Near Term Case Study Integrated Approach to Testing and Assessment to Inform Regulatory Decisions (PDF) (15 pp, 561.48K)
Moving From Data Requirements to Knowledge Requirements to Inform Risk Assessment and Regulatory Decisions (PDF) (16 pp, 764.06K)
Priority Setting: Using new predictive computer models and in vitro tools (PDF) (17 pp, 312.54K)

May 12, 2010 (PDF) (1 pg, 22K) - The key discussion topics included the Draft Proposal for the One-Day Stakeholder Meeting on November 16, 2010, the Draft Proposal for One-Day Stakeholder Meeting on Biomarkers in April 2011, the Metrics Subgroup, the Biomarker Subgroup, and the Stakeholder Issues Subgroup.

Agenda

April 29, 2010 – The key discussion topics included the Draft Proposal for one-day stakeholder meeting agenda and the Draft Proposal for one-day stakeholder meeting agenda on biomonitoring.

Executive Summary (PDF) (1 pg, 18K)

March 3, 2010 (PDF) (1 pg, 14.13K) - The key discussion topics included the circulation of the draft one-day FACA agenda on “21st Century Toxicology and Integrated Testing Strategies” as well as a discussion on the need to promote research on the development of post-market surveillance methods with respect to biomarkers.

Agenda

January 13, 2010 (PDF) (1 pg, 13.12K) - E. Cohen-Hubal EPA/ORD/NCCT gave a presentation entitled “Exposure Science for Chemical Management: Does Exposure Imitate Art?

Agenda
Exposure Science for Chemical Management: Does Exposure Imitate Art? (PDF) (38pp, 1.90MB)

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2009

December 9, 2009 - Key discussion topics included general planning for a one-day stakeholder/FACA meeting in 2010 as well as an agreement to meet every other month in 2010.

Agenda
Executive Summary (PDF) (1 pg, 24.50K)

October 14, 2009 - Continuation of October 13 meeting.

Metrics of Success Subgroup (PDF) (12 pp, 37.25K)
Issues Subgroup (Q&A Format) (PDF) (15 pp, 214.83K)
Biomonitoring Subcommittee Biomarker Seminar (PDF) (12 pp, 420.12K)

October 13, 2009 - Key topics included the Seminar on Biomarkers, One-Day Stakeholder/FACA Meeting, and proposed 2010 Activities.

Agenda
Medical Management of Pesticide Poisoning: Why We Need Diagnostic Tools (PDF) (30 pp, 177.24K) by, James R. Roberts, MD, MPH
Why Do We Need Diagnostic Tests and Biomarkers for Pesticides? (PDF) (27 pp, 486.69K) by, Matthew Keifer MD, MPH
Executive Summary (PDF) (1 pg, 19.35K)

September 9, 2009 - Key topics included updates on the Integrative Testing web pages, Exposure activities, and ToxCas.

Agenda
Executive Summary (PDF) (1 pg, 27.28K)

July 8, 2009 - The key topics included a MetaPath and DER Composer presentation by Dr. Patricia Schmieder and discussion on the Metrics of Success and Stakeholder Issues.

Agenda
Metabolic Simulator presentation (PDF) (22 pp, 749K) by, Dr. Patricia Schmieder
Executive Summary (PDF) (1 pg, 21.71K)

June 10, 2009 - J. Paterson, chair of the Metrics subgroup, reported on its June 8, 2009, meeting. The subgroup will explore two types of metrics: metrics of success and metrics of progress. The group also discussion ideas for the One-Day Stakeholder/FACA meeting.

Agenda
Executive Summary(PDF) (1 pg, 23.27K)

May 20, 2009 - J. Paterson offered some suggestions for metrics of success and stakeholder issues.

April 23, 2009 - Key topics included a presentation on Diagnostic Biomarkers of Effect and Exposure.

March 3, 2009 - Key topics included a presentation on Cancer Bioassay by Dr. Mary Manibusan (OPP Health Effects Division), and a presentation on Enhanced F1 Tiered Testing Approach by Dr. Elizabeth Mendez (OPP Health Effects Division).

February 3, 2009 - Key topic was a presentation on ToxCast™ by Dr. David Dix (National Center for Computational Toxicology).

Agenda
Presentation (PDF) (43 pp, 3.30MB)

January 6, 2009 - Key topic was a presentation on DA QSAR systems by Dr. Edwin Matthews.

Agenda
Presentation (PDF) (60 pp, 277K)

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2008

December 2, 2008 - Key discussion topics included Member ideas for workgroup outputs.

November 13, 2008 - Key topics included finalizing the Work Group charge and and presentation on Update on Research Using in vitro and Computer-based Tools for Screening Potential Estrogenic Activity.