Advancing the Next Generation (NexGen) of Risk Assessment
Conferences and Workshops
Recent Workshops
[Jan 2012] Systems Biology-Informed Risk Assessment Workshop 
[Dec 2011] Emerging Technologies for Measuring Individual Exposomes (Washington, DC) 
[Sep 2011] Applying 21st Century Toxicology to Green Chemical and Material Design (Washington, DC) 
[Feb 2011] Advancing the Next Generation (NexGen) of Risk Assessment
Public Dialogue Conference
The U.S. Environmental Protection Agency (EPA) is embarking on an exploration of the new science and methods that are ripe for incorporation into currently emerging and future risk assessments. The landscape of risk assessment is changing with new advances in molecular systems biology, the advent of several recent and important reports from the National Research Council, and volumes of new test data emerging from the Tox21 and European REACH programs.This program "Advancing the Next Generation of Risk Assessment (NexGen)" is a collaborative effort among EPA, National Institutes of Environmental Health Sciences/National Toxicology Program, National Human Genome Research Institute, Centers for Disease Control/Agency for Toxic Substance Disease Registry, and the State of Californias Environmental Protection Agency. So on February 15 and 16, 2011, EPA held a conference in Washington, DC, to engage the public in the early stages of the NexGen program, share information, and receive feedback. NexGen is a component of EPAs Safer Products, Sustainable World Initiative.
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Summary Report of Advancing the Next Generation of Risk Assessment Public Dialogue Conference (draft) - Public Dialogue Conference Summary (32 pp, 899 K, About PDF )
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Agenda & Recordings of Presentations:
- Welcome and Introduction - Ms. Becki Clark
- Vision for Safer Chemicals, Sustainable World - Dr. Paul Anastas:
Video -
This video includes both the Welcome and Introduction as well as Vision for Safer Chemicals content.
- Vision for Safer Chemicals, Sustainable World - Dr. Paul Anastas:
Video -
- Linking Research to Risk Assessment, Dr. Linda Birnbaum: Video | Presentation (43 pp, 11.26 MB, About PDF )
- The Next Generation of Risk Assessment (NexGen) Program: Overview and Invitation to Engage - Dr. Ila Cote: Video | Presentation (24 pp, 658 K, About PDF )
- The Next Generation of Risk Assessment (NexGen): A Proposed Framework Dr. Daniel Krewski: Video | Presentation (39 pp, 6.09 MB, About PDF )
- Example Approaches to Understanding Human Health Risks Associated with Environmental Exposures to Chemicals
- Ozone - Dr. Robert Devlin: Video | Presentation (29 pp, 6.87 MB, About PDF )
- Benzene - Dr. Martyn Smith: Video | Presentation (25 pp, 5.67 MB, About PDF )
- Human Health Risk Assessment Approaches for Chemicals with Limited Data - Dr. David Dix: Video | Presentation (28 pp, 4.73 MB, About PDF )
- Question and Answer Session with Speaker Panel: Video
- Common Themes Heard - Dr Doug Crawford-Brown: Video | Presentation (9 pp, 172 K, About PDF )
- Welcome and Introduction - Ms. Becki Clark
Past Workshops
- A BLUEPRINT of Haematopoietic Epigenomes (2010)
- Advancing the Next Generation (NexGen) if Risk Assessment: The Prototypes Workshop ( 2010) ( 34 pp, 542 K, About PDF )
- NTP Workshop: Role of Environmental Chemicals in the Development of Diabetes and Obesity (2011)
- Presentation at the Society for Risk Analysis Annual Meeting (2010)
(208 pp, 3.75MB, About PDF )
The Next Generation of Risk Assessment. Cote I, Barone S, Dix D, Judson R, Edwards S, Devlin R, Avery J, Preuss P US Environmental Protection Agency
- Standing Committee on Use of Emerging Science for Environmental Health Decisions
- More info: http://dels-old.nas.edu/envirohealth/ - Toxicity Pathway-Based Risk Assessment: Preparing for Paradigm Change: A Symposium Summary (2010)
- Use of In Utero and Post-Natal Indicators to Predict Health Outcomes Later in Life (October 2010) [Workshop Presentations | Suggested Reading ]
- Stem Cell Models for Environmental Health (June 2010)
- Computational Toxicology: From Data to Analyses to Applications (September 2009)
- Science and Decisions: Advancing Risk Assessment (December 2008)
- Toxicity Testing in the 21st Century: A Vision and a Strategy (June 2007)