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Index of Cleared Science Reviews for Metalaxyl (Pc Code 113501)
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Undated. Memorandum. 2 Page(s).
Dave Coppage. Ecological Effects Branch.
Review of Phytotoxicity Data for Metalaxyl. Acc. No. 257626.
Document(PDF) (61 KB PDF).
Undated. Memorandum. 3 Page(s).
George Tompkins. Environmental Fate & Ground Water Branch.
Environmental Fate Studies to be Included in Data Call In Notice for Metalaxyl (113501).
Document(PDF) (94 KB PDF).
Undated. Memorandum. 5 Page(s).
Estella Waldman. Environmental Fate & Ground Water Branch.
Amendment to Ground Water Assessment of Metalaxyl for Registration Eligibility Document.
Document(PDF) (511 KB PDF).
September 08, 1976. Review. 6 Page(s).
Ecological Effects Branch..
TEST: Avian subacute dietary LC50 Japanese Quail Accession No. 234439
Avian subacute dietary and avian acute oral studies attached.
Document(PDF) (359 KB PDF).
October 06, 1978. Review. 10 Page(s).
Clayton Bushong. Ecological Effects Branch.
100-EUP-1. PP#8G2121. EPA Reg. No 100-601. EUP and Petition to test product
efficacy on Potato late blight.
Document(PDF) (412 KB PDF).
November 08, 1978. Review. 4 Page(s).
W. Woodrow. Toxicology Branch.
EUP proposed for evaluation of Ridomil 2E for black shank control on tobacco. Acute
oral, rats. Acc 234429. Acute dermal, rabbits. Primary eye irritation, rats. Primary skin
irritation,… Teratology, rats. Acc 224428. Inert ingredient info on p. 1 deleted.
Document(PDF) (247 KB PDF).
November 27, 1978. Review. 13 Page(s).
W. Woodrow. Toxicology Branch.
Request for EUP and temporary tolerance for Ridomil 2E used as systemic fungicide
to control potato late blight. EPA Acc. No. 234429, 2344281, 097382. 100-EUP-1.
Inert ingredient info. on page 1 and 3 deleted.
Manufacturing process info. on page 2 deleted.
Document(PDF) (794 KB PDF).
December 01, 1978. Review. 5 Page(s).
Robert F. Carsel. Environmental Fate Branch.
100-EUP-62 Experimental Use permit: control of black shank on tobacco.
Document(PDF) (155 KB PDF).
December 10, 1978. Review. 2 Page(s).
Ecological Effects Branch..
Test: Aquatic Invertebrate LC50 Daphnia magna. Accession No. 236854.
Document(PDF) (72 KB PDF).
December 22, 1978. Review. 2 Page(s).
Ecological Effects Branch..
Test: Fish Acute 96-hr LC50 (warmwater) Bluegill. Accession No. 236854.
Document(PDF) (87 KB PDF).
December 25, 1978. Review. 2 Page(s).
Ecological Effects Branch..
Test: Fish Acute 96-hr LC50 (coldwater) Rainbow trout. Accession No. 236854.
Document(PDF) (60 KB PDF).
February 26, 1979. Review. 39 Page(s).
Gunter Zweig. Environmantal Fate Branch.
Environmental Fate Review of Reg./File No.: 100-ANN to use on non-bearing
citrus (FA.) and ornamentals.
Document(PDF) (1417 KB PDF).
February 26, 1979. Review. 4 Page(s).
Ronald Ney. Environmental Fate Branch.
100-ANR. Ridomil. Registration of Technical Product.
Document(PDF) (148 KB PDF).
February 27, 1979. Review. 6 Page(s).
William Woodrow. Toxicology Branch.
EUP for evaluation of Ridomil-2E for black shank control on tobacco. 100-EUP-63
Inert ingredient information on pages 2 and 3 not included.
Document(PDF) (254 KB PDF).
March 27, 1979. Review. 8 Page(s).
John Tice. Ecological Effects Branch.
100 ANR. PP #8G2121. Ridomil. Registration of Technical Product.
Document(PDF) (373 KB PDF).
March 30, 1979. Review. 5 Page(s).
William Butler. Toxicology Branch.
The Request to register I. Technical CGA-48988 (Ridomil), EPA #100-ANR
for formulation use II. Formulation CGA48988, 5W, EPA #100-ANN.
Document(PDF) (318 KB PDF).
May 07, 1979. Review. 12 Page(s).
Edward B. Brittin. Residue Chemistry Branch, HED.
100-EUP-62; Experimental use permit for Ridomil on Tobacco.
Document(PDF) (906 KB PDF).
June 15, 1979. Review. 13 Page(s).
William Woodrow. Toxicology Branch.
Ridomil-2EG Request for EUP and temporary tolerance at 0.05 ppm on potatoes to control
potato late blight. 100-EUP-1, 8G2121. Inert ingredient info on pages 1-6 is not included.
Document(PDF) (809 KB PDF).
October 24, 1979. Review. 22 Page(s).
Gunter Zweig. Environmantal Fate Branch.
100-ANN non-bearing citrus and ornamental turf. Acc. 238231, 238232.
Document(PDF) (930 KB PDF).
December 06, 1979. Review. 2 Page(s).
Carl Grable. Fungicide-Herbicide Branch.
100-607 conditional registration for use on tobacco to control black shank and blue mold.
Acc. 241240, 241241, 241242.
Document(PDF) (52 KB PDF).
January 21, 1980. Review. 20 Page(s).
Clayton Bushong. Ecological Effects Branch.
100-ANN Full registration of new chemical for certain diseases of ornamentals, turf
and non-bearing citrus. Acc. 234439.
Document(PDF) (838 KB PDF).
February 11, 1980. Review. 4 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. # 100-ANT; Ridomil 2E CASWELL # 375AA (metalaxyl) Interim report of a 4-week
toxicity study of the pyrolysis products of CGA-48988 in cigarette tobacco smoke.
Document(PDF) (232 KB PDF).
March 03, 1980. Review. 1 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. # 100-ANN; 100-ANT; Ridomil and Subdue; 21-Day Subacute Dermal Toxicity Requirement.
Document(PDF) (36 KB PDF).
March 16, 1980. Data Eval. Rec. 6 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: Fish Embryo-larvae Fathead minnow. Accession No. 244183.
Document(PDF) (216 KB PDF).
March 17, 1980. Review. 6 Page(s).
John Leitzke. Ecological Effects Branch.
100-ANT Conditional registration on tobacco.
Document(PDF) (252 KB PDF).
March 19, 1980. Review. 12 Page(s).
Lynn Bradley. Residue Chemistry Branch.
EPA Registration Number 100-607. Ridomil. Request for Conditional Registration
on Tobacco. Manufacturing process information on page 2 not included.
Document(PDF) (502 KB PDF).
April 01, 1980. Review. 7 Page(s).
John McCann. Chemical & Biological Investigations.
Terrestrial and Aquatic Biology Work on "Rid-O-Mil 5% WP".
Document(PDF) (413 KB PDF).
May 06, 1980. Review. 19 Page(s).
Gunter Zweig. Environmantal Fate Branch.
100-ANT Tobacco (rotational crops). Acc. 241243.
Document(PDF) (746 KB PDF).
June 10, 1980. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. # 100-607; Subacute Inhalation Toxicity Pilot Study in Rats with CGA-48988
- Spiked cigarettes. CASWELL # 375AA.
Document(PDF) (140 KB PDF).
November 21, 1980. Review. 3 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 amend "General Information" and "Tobacco Plant Bed Direc- tions for Use"
portions of label.
Document(PDF) (104 KB PDF).
January 12, 1981. Review. 2 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 to add directions for use to control black shank on field planted tobacco
(other than flue-cured tobacco).
Document(PDF) (62 KB PDF).
January 12, 1981. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 review groundwater monitoring data, protocol review, add non-bearing citrus
to label, requests for numerous administrative dicisions.
Document(PDF) (173 KB PDF).
January 29, 1981. Memorandum. 1 Page(s).
Edward Zager. Residue Chemistry Branch.
EPA Reg. No. 100-607. Ridomil 2E Fungicide (Metalaxyl) on crops grown for seed production only.
Document(PDF) (47 KB PDF).
March 11, 1981. Data Eval. Rec. 9 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: Invertebrate Life-cycle Daphnia magna. Accession No. 244183.
Document(PDF) (274 KB PDF).
March 11, 1981. Review. 9 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Conditional registration follow-up - 5th groundwater monitoring study.
Document(PDF) (378 KB PDF).
March 17, 1981. Data Eval. Rec. 8 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: 96-hour fish LC50 Bluegill. Accession No. 244183.
Document(PDF) (321 KB PDF).
Attachment(s) Following:
July 24, 1979. Review.
John A. M.. Ecological Effects Branch.
Biological Report of Analysis Static jar. Test #2416. Daphnia magna.
*End of Attachments*
April 06, 1981. Data Eval. Rec. 4 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: 96-hr LC50 Bluegill. Acc. No. 244183.
Document(PDF) (171 KB PDF).
April 07, 1981. Data Eval. Rec. 4 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: 96-hr fish LC50 Rainbow trout. Acc. No. 244183.
Document(PDF) (153 KB PDF).
April 08, 1981. Review. 11 Page(s).
James Felkel. Ecological Effects Branch.
100-607 Submission of data in response to previous EEB review. Acc. 244183.
Inert ingredient information on pages 2, 3 is not included.
Document(PDF) (559 KB PDF).
April 24, 1981. Review. 5 Page(s).
John Tice. Ecological Effects Branch.
100-607 Proposed conditional registration for use in conifer nurseries.
Document(PDF) (184 KB PDF).
April 28, 1981. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg.# 100-607; Ridomil 2E Fungicide; Request for amended registration
of Ridomil 2E to permit use in conifer nurseries. CASWELL#375AA.
Document(PDF) (75 KB PDF).
April 28, 1981. Review. 4 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 Add: foliar applications in tobacco plant beds for blue mold control
and use on nonbearing citrus to control Phytphthora root and foot rot.
Document(PDF) (231 KB PDF).
May 11, 1981. Review. 3 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 add: 8 vegetable and 3 field crops to control certain Pythium, Phytophtora,
and downy mildew diseases.
Document(PDF) (147 KB PDF).
May 13, 1981. Data Eval. Rec. 3 Page(s).
James Felkel. Ecological Effects Branch.
Test Type: Invertebrate life-cycle (addendum) Daphnia magna. Acc. No. 244782.
Document(PDF) (136 KB PDF).
May 21, 1981. Memorandum. 19 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg.# 100-607; Ridomil 2E; PP#1F2500; 1H5299; Metalaxyl: [N-(2,6-dimethylphenyl) -N-
(methoxyacetyl) alanine methyl est and its metabolites containing the 2,6-dimethlalinine
moiety each expressed as metalaxyl in or on the following...
Tox review 003310.
Document(PDF) (1121 KB PDF).
May 26, 1981. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Review of 6th groundwater monitoring study.
Document(PDF) (122 KB PDF).
May 27, 1981. Review. 1 Page(s).
James Felkel. Ecological Effects Branch.
Registration # 100-607 (Metalaxyl): review of daphnid life-cycle study data.
Document(PDF) (31 KB PDF).
June 19, 1981. Review. 14 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Add use on cottonseed, soybeans, wheat, and certain vegetable crops.
Document(PDF) (647 KB PDF).
June 19, 1981. Review. 5 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Use on conifer nurseries for control of root rot.
Document(PDF) (283 KB PDF).
June 25, 1981. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg.# 100-607; Ridomil 2E, Amended registration; PP#1F2531, Metalaxyl
in/on avocados at 4.0 ppm CASWELL#375AA Acc. 070149.
Document(PDF) (47 KB PDF).
June 26, 1981. Review. 14 Page(s).
John Tice. Ecological Effects Branch.
100-607 Proposed registration of additional uses: broccoli, cabbage, cauliflower,
cotton, cucumbers, lettuce, melons, onions, potatoes, soybeans, spinach, tomatoes,
& wheat. Inert ingredient info pages 6 and 12 is not included.
Document(PDF) (1041 KB PDF).
June 26, 1981. Review. 6 Page(s).
John Tice. Ecological Effects Branch.
100-607 Proposed conditional registration of Avocados Use.
Document(PDF) (291 KB PDF).
July 02, 1981. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Meatalaxyl; EPA Reg. # 100-607; Use on Cottonseed, soybeans, wheat and certain
vegetable crops.
Document(PDF) (44 KB PDF).
July 02, 1981. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Metalaxyl; EPA Reg.# 100-607; Use on conifer nurseries for control of root rot;
CASWELL#375AA.
Document(PDF) (44 KB PDF).
August 12, 1981. Review. 30 Page(s).
Willa Garner. Environmental Fate Branch.
CGA-62826 acid degradate of metalaxyl # 100-607 In ground water when used on [various crops].
Document(PDF) (1043 KB PDF).
August 24, 1981. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Adding new use - avocados.
Document(PDF) (94 KB PDF).
August 31, 1981. Review. 6 Page(s).
John Tice. Ecological Effects Branch.
100-607 Proposed conditional registration of hops use.
Inert ingredient information on page 6 is not included.
Document(PDF) (206 KB PDF).
September 21, 1981. Review. 14 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 groundwater monitoring data.
Document(PDF) (835 KB PDF).
September 21, 1981. Review. 2 Page(s).
Sami Malak. Environmental Fate Branch.
Ciba-Geigy is requesting review of eighth ground water monitoring studies.
Document(PDF) (121 KB PDF).
December 01, 1981. Review. 3 Page(s).
Sami Malak. Environmental Fate Branch.
100-607 9th groundwater monitoring status.
Document(PDF) (159 KB PDF).
April 14, 1982. Review. 2 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 Add: tobacco layby application; prohibition of tobacco foliar applications;
revised resistant strains statement; tank-mixture uses on cucumbers, melons, onions,
potatoes, & tomatoes.
Document(PDF) (99 KB PDF).
April 23, 1982. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
100-607 Review of 10th Groundwater Monitoring Study.
Document(PDF) (169 KB PDF).
April 27, 1982. Memorandum. 6 Page(s).
William Dykstra. Toxicology Branch, Hazard Evaluation Div.
Metalaxyl; Ridomil 2E; EPA Reg. No. 100-607; PP# 1F2500/1H5299; Metalaxyl
in/on various crops, Accession No. 070767-769.
Document(PDF) (289 KB PDF).
May 06, 1982. Memorandum. 9 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 100-AE Ridomil 5G Fungicide Acute Studies.
Accession Number 247083. Pages 5-9 removed, draft label. Tox review 002821.
Document(PDF) (375 KB PDF).
May 14, 1982. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
Metalaxyl; Ridomil 2E; EPA Reg.# 100-607; 100-EUP-TR; PP#1G2532; 1H5314;
Metalaxyl in/on various crops; Recalculation of ADI.
Document(PDF) (80 KB PDF).
June 16, 1982. Review. 1 Page(s).
Henry Jacoby. Fungicide Herbicide Branch.
Conditions of Registration for Ridomil (Metaloxyl) on tobacco.
Document(PDF) (81 KB PDF).
July 26, 1982. Review. 1 Page(s).
T. Aiken. Fungicide Herbicide Branch.
EPA File Symbol 100-601. Corrections to Confidential Statement of Formula.
Manufacturing process information on page 1 is not included.
Document(PDF) (67 KB PDF).
July 29, 1982. Memorandum. 11 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 100-AEO Ridomil MZ58 Fungicide Acute studies... Acc 247494.
Pages 5-11 removed, draft label. Tox review 005431.
Document(PDF) (508 KB PDF).
August 16, 1982. Review. 1 Page(s).
Richard Michell. Fungicide-Herbicide Branch.
100-607 (added uses) Cotton - Seed Rots and Seedling Diseases (Pythium spp.),
in-furrow-treatment.
Document(PDF) (40 KB PDF).
September 08, 1982. Review. 4 Page(s).
Daniel Rieder. Ecological Effects Branch.
100-607 Proposed Conditional Registration of Squash Use.
Document(PDF) (181 KB PDF).
September 17, 1982. Memorandum. 2 Page(s).
Charles Trichilo. Residue Chemistry Branch.
Metalaxyl Registration Standard Product Chemistry Chapter.
Quality control procedure information on page 1 not included.
Document(PDF) (136 KB PDF).
October 07, 1982. Review. 2 Page(s).
James Felkel. Ecological Effects Branch.
100-607 Proposed conditional registration to permit rotation to wheat and soybeans.
Document(PDF) (85 KB PDF).
October 12, 1982. Review. 2 Page(s).
Samuel Creeger. Environmental Fate Branch.
100-607 new use on squash.
Document(PDF) (65 KB PDF).
October 13, 1982. Review. 4 Page(s).
Carol Natella. Ecological Effects Branch.
100-607 Amendment to add pineapple "seed piece dip" for control of heart rot
disease of pineapple caused by Phytophthora.
Document(PDF) (216 KB PDF).
October 18, 1982. Review. 2 Page(s).
Samuel Creeger. Environmental Fate Branch.
100-607 Review data to support use pattern-seed piece dip for pineapple.
Document(PDF) (63 KB PDF).
October 20, 1982. Review. 2 Page(s).
Samuel Creeger. Environmental Assessment Branch.
100-607 amend rotational crop restriction.
Document(PDF) (71 KB PDF).
November 08, 1982. Memorandum. 2 Page(s).
Charles Trichilo. Residue Chemistry Branch.
100-601 New confidential statement of formula for technical metalaxyl.
Inert ingredient information on page 1 is not included.
Document(PDF) (72 KB PDF).
November 18, 1982. Memorandum. 31 Page(s).
Stanley Gross. Toxicology Branch.
Metalaxyl, 100-607/ 2500. Submission of Additional Data:
Mouse oncogenesis, mutagenicity studies and 90 day smoke inhalation study.
Pages 6, 8-12, 14-18 removed, registrant data. Tox review 005778.
Document(PDF) (1995 KB PDF).
January 18, 1983. Review. 8 Page(s).
Ann Stavola. Ecological Effects Branch.
100-607 Proposed conditional Registration of Bearing Citrus Use.
Document(PDF) (390 KB PDF).
January 28, 1983. Review. 2 Page(s).
Emil Regelman. Environmental Fate Branch.
100-607 Amended use-on bearing citrus.
Document(PDF) (62 KB PDF).
April 22, 1983. Memorandum. 7 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
Reg. No 100-607 Acute oral, acute dermal, acute inhalation, eye irritation
and dermal sensitization. Acc 249614. Tox review 005019.
Document(PDF) (495 KB PDF).
April 29, 1983. Review. 6 Page(s).
Roger Gardner. Toxicology Branch.
Metalaxyl Mouse Oncogenicity Study. Registration No. 100- 607, Acc. No. 247660.
MRID 00103354 Tox Chem. No. 375AA.
Document(PDF) (376 KB PDF).
May 06, 1983. Review. 2 Page(s).
Carl Grable. Fungicide-Herbicide Branch.
100-607 Efficacy Review add control of Phytophthora root rot of non-bearing fruit
and nut trees in nurseries and field plantings.
Document(PDF) (64 KB PDF).
July 20, 1983. Memorandum. 7 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 538-RIL Proturf Pytheum Control (acute studies...) Acc 249999.
Pages 4-7 removed, draft label. Tox review 005135.
Document(PDF) (533 KB PDF).
July 22, 1983. Review. 2 Page(s).
Carl Grable. Fungicide-Herbicide Branch.
100-607 to control seedling diseases and pod rot caused by Pythium spp. on peanuts.
Document(PDF) (67 KB PDF).
July 26, 1983. Review. 2 Page(s).
Carl Grable. Fungicide-Herbicide Branch.
Efficacy Review new uses: legume vegetables.
Document(PDF) (67 KB PDF).
August 08, 1983. Memorandum. 5 Page(s).
Bertram Litt. Toxicology Branch.
Metalaxyl; Rat and Mouse Chronic Feeding Studies; Further Assessment of
Oncogenic Potential Including Statistical Analysis and Risk Assessment.
Document(PDF) (282 KB PDF).
September 06, 1983. Review. 6 Page(s).
Richard Lee. Ecological Effects Branch.
100-607 Proposed conditional registration of legume vegetables use.
Document(PDF) (276 KB PDF).
September 09, 1983. Review. 2 Page(s).
Richard Moraski. Exposure Assessment Branch.
100-607 New Use on legume vegetables.
Document(PDF) (66 KB PDF).
September 09, 1983. Review. 2 Page(s).
Richard Moraski. Exposure Assessment Branch.
100-607 New Use on tobacco, cotton, avocados, nonbearing citrus, nonbearing
deciduous fruits and nuts, conifers in nurseries, and certain vegetable crops.
Document(PDF) (71 KB PDF).
September 12, 1983. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. No.: 100-607; Soil Application of Metalaxyl for Cucurbits, Onions,
Lettuce and Spinach.
Document(PDF) (39 KB PDF).
October 20, 1983. Memorandum. 7 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 501-42 Gustafson (acute studies...)
Accession Number 251408. Pages 5-7 removed, draft label. Tox review 005032.
Document(PDF) (316 KB PDF).
November 04, 1983. Review. 5 Page(s).
Curtis Laird. Ecological Effects Branch.
EPA Reg. No.: 100-607. Proposed conditional registration of soil applications
on broccoli, cabbage, and cauliflower.
Document(PDF) (217 KB PDF).
December 08, 1983. Memorandum. 5 Page(s).
Nancy Dodd. Residue Chemistry Branch.
EPA Reg. No. 100-607. Amended Registration for Metalaxyl on Lettuce and Spinach.
(Accession No 251021).
Document(PDF) (299 KB PDF).
January 23, 1984. Memorandum. 7 Page(s).
Nancy Dodd. Residue Chemistry Branch.
EPA Registration No. 100-607 Amended Registration for Metalaxyl on Cucurbits and Onions.
Accessions Nos. 251019 and 251020.
Document(PDF) (470 KB PDF).
February 13, 1984. Memorandum. 3 Page(s).
Bernard Haberman. Carcinogen Assessment Group.
Review of the Metalaxyl Fungicide Mouse Oncogenicity Study.
Document(PDF) (187 KB PDF).
August 01, 1984. Memorandum. 3 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 7501-42 Gustafson Apron-FL Seed Protectant Acute inhalation data,
LD50 acute oral. Page 3 removed, draft label. Tox review 005195.
Document(PDF) (1625 KB PDF).
March 19, 1985. Memorandum. 1 Page(s).
Bernard Haberman. Carcinogen Assessment Group.
Review of Rat Pheochromocytoma Data on Metalaxyl.
Document(PDF) (56 KB PDF).
April 01, 1985. Review. 1 Page(s).
Chad Sandusky. Toxicology Branch.
100-601. Re-reading of histopathology from the mouse chronic oncogenicity study.
Document(PDF) (65 KB PDF).
April 25, 1985. Review. 37 Page(s).
Chad Sandusky. Toxicology Branch.
Review of Repeat Teratology Studies (Rat and Rabbit) on metalaxyl. Acc. No 255939, 255994,
257329-rabbit and 256380, 257329-rat. Pages 12-19, 28-37 removed, registrant data.
Document(PDF) (1006 KB PDF).
June 20, 1985. Review. 3 Page(s).
Michael Slimak. Ecological Effects Branch.
100-601. Submission of data for aquatic macrophytes and algae.
Review of phytotoxicity data for Metalaxyl. Acc. No. 257626.
Document(PDF) (92 KB PDF).
June 27, 1985. Review. 1 Page(s).
Chad Sandusky. Toxicology Branch.
100-601. Review of information, including a 28-day range finding study in rats,
submitted by Ciba-Geigy to support the use of an MTD in the 2-year
chronic/oncogenicity study. Acc. No. 255590.
Document(PDF) (67 KB PDF).
June 27, 1985. Review. 1 Page(s).
Chad Sandusky. Toxicology Branch.
100-607. Review of a 32-day interim report of a 90-day range finding study in mice
to support the MTD in the mouse oncogenicity study. Acc. No. 256795 and 256796.
Document(PDF) (67 KB PDF).
July 26, 1985. Review. 2 Page(s).
Henry Jacoby. Fungicide Herbicide Branch.
Metalaxyl Technical Fungicide EPA Registration No. 100-601 Data Submission of April 10, 1984.
Document(PDF) (191 KB PDF).
November 05, 1985. Memorandum. 45 Page(s).
Linda Kutney. Residue Chemistry Branch.
PP# 3F2818 and 2F2764 (RCB #1368 and #1369). Metalaxyl on and Soybean Byproducts.
Amendment of 7/18/85 for withdrawal of cotton soapstock. (No accession number).
Document(PDF) (1114 KB PDF).
Attachment(s) Following:
April 06, 1983. Memorandum.
K. H. Arne. Residue Chemistry Branch.
PP#2F2764/FAP#2H5369. Rotational crop tolerances for Metalaxyl on
soybeans and wheat. Evaluation of Analytical Method and Residue Data.
June 13, 1983. Memorandum.
K. H. Arne. Residue Chemistry Branch.
PP#2F2764/FAP#2H5369. Rotational crop tolerance for metalaxyl
on soybeans and wheat. Amendment of January 26, 1983.
August 30, 1983. Memorandum.
K. H. Arne. Residue Chemistry Branch.
PP#2F2564. Metalaxyl on soybeans and wheat. Amendment of May 16, 1983.
*End of Attachments*
December 31, 1985. Memorandum. 7 Page(s).
Reto Engler. Toxicology Branch.
Peer Review of Metalaxyl, Tox. Chem. No. 275AA
Pending registration information on page 2 is not included.
Document(PDF) (562 KB PDF).
January 13, 1986. Memorandum. 3 Page(s).
Richard Loranger. Residue Chemistry Branch.
EPA Reg. Nos. 100-626*, -639. Additional data and amended labels for metalaxyl
seed treatments. Accession Number 258986. [RCB# 117, 118] MRID 153158.
Document(PDF) (119 KB PDF).
February 07, 1986. Memorandum. 7 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#6F3330 (RCB #312). Metalaxyl on Asparagus. Evaluation of Analytical
Methods and Residue Data (Accession Numbers 260562 and 260563). MRID 154446.
Document(PDF) (194 KB PDF).
February 14, 1986. Memorandum. 5 Page(s).
William L. Anthony. Residue Chemistry Branch.
EPA Reg.#100-629 Metalaxyl [RIDOMIL®-MZ58]: [RCB #601 [Acc.#259156]
Amended Registration.
Document(PDF) (175 KB PDF).
February 21, 1986. Memorandum. 10 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#6F3337 (RCD#360) - Metalaxyl on Strawberries - Evaluation of Analytical
Methods and Residue Data (Accession Numbers 260658 and 260659). MRID 155237.
Document(PDF) (309 KB PDF).
March 12, 1986. Memorandum. 9 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 100-628 Ridomil 5G Fungicide (acute studies...)
Accession Number 258034. pages 6-9 removed, draft label. Tox review 006207.
Document(PDF) (436 KB PDF).
March 27, 1986. Memorandum. 9 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol: 538-ENG Proturf Fluid Fungicide II (acute studies...)
Accession Number 258183. Pages 6-9 removed, draft label. Tox review 006262.
Document(PDF) (408 KB PDF).
April 04, 1986. Memorandum. 7 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 100-ALI Ridomil/Bravo 81W Fungicide Acute studies.
Accession Number 257976. Tox review 006192. Page 7 removed-draft label.
Document(PDF) (552 KB PDF).
June 12, 1986. Memorandum. 9 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 100- Ridomil PC 11G Granular Fungicide Acute studies.
Accession Number 259739. Tox review 006030.
Document(PDF) (896 KB PDF).
August 20, 1986. Memorandum. 79 Page(s).
Jane Harris. Toxicology Branch.
Review of Mutagenicity Data on Technical Grade Metalaxyl. EPA Reg No 100-601.
Tox Chem 375AA. Accession Numbers 260496, 263117 Tox review 005372.
Document(PDF) (3553 KB PDF).
Attachment(s) Following:
August 12, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Experimental Pathology Lab.
August 12, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Experimental Pathology Laboratories.
Pages 8-11 are not included-registrant data.
August 12, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Institute of Environmental Toxicology, Toxicity Dept.
August 12, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Pharmaceuticals Div., Toxicology/Pathology,
CIBA-GEIGY Limited.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-1 Acute Oral Toxicity. LD50 Hamster. Experimental Pathology Laboratories.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-1. Acute Oral Toxicity. LD50 Mouse. Experimental Pathology Laboratories.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Experimental Pathology Lab.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Experimental Pathology Laboratories.
Page 5 is not included-registrant data.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Hazleton Biotechnologies.
Page 10, 12-15 are not included-registrant data.
August 13, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2. Mutagenicity. Experimental Pathology Lab.
August 19, 1986. Data Eval. Rec.
Jane Harris. Toxicology Branch.
Guideline 84-2 Mutagenicity. Experimental Pathology Lab.
*End of Attachments*
September 03, 1986. Memorandum. 3 Page(s).
Kenneth Dockter. Residue Chemistry Branch.
EPA Reg. No. 100-639. Apron 25W (metalaxyl) label amendment with cover letter dated
3/14/86 to increase use rate on corn seed for export only. No Accession No. RCB #1147.
Document(PDF) (90 KB PDF).
September 05, 1986. Memorandum. 3 Page(s).
Jane Harris. Toxicology Branch.
Review of a range finding study in mice with Technical Grade Metalaxyl.
EPA Reg No 100-601. Tox Chem 375AA. Tox review 005442.
Document(PDF) (445 KB PDF).
Attachment(s) Following:
September 03, 1986. Data Eval. Rec. 6 Page(s).
Jane Harris. Toxicology Branch.
Guideline 82-1. Subchronic Toxicity (Chronic/Oncogenicity Range Finding).
Life Sciences Research Limited. Acc. Nos. 258811 and 258812. MRID 148087
Tox review 005442.
*End of Attachments*
September 08, 1986. Memorandum. 5 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#6F3337 (RCB #988) - Metalaxyl on Strawberries - Evaluation of Amendment
Dated April 11, 1986 (Accession No. 260669). MRID 155237.
Document(PDF) (133 KB PDF).
September 26, 1986. Memorandum. 18 Page(s).
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Cucurbits), Sugar
Beets, and Sugar Beet Tops Evaluation of Analytical Method and Residue Data
(Accession Numbers 262111 and 262112) [RCB Numbers 768 and 7691].
MRID 157478-157480.
Document(PDF) (780 KB PDF).
September 30, 1986. Review. 19 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
EPA Reg. No 100-601. Ridomol. Ground and surface water Monitoring studies were
voluntarily submitted, although not in response to any registration requirement.
Pages 7-19 removed, registrant data.
Document(PDF) (396 KB PDF).
January 12, 1987. Memorandum. 11 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 100-ATN Apron Plus Captan Fungicide Seed Protectant (acute studies)
Accession Number 265182. Pages 7-11 removed, draft label. Tox review 006369.
Document(PDF) (524 KB PDF).
February 18, 1987. Review. 73 Page(s).
Roger Gardner. Toxicology Branch.
Registration No(s). 100-601. Pesticide Petition No(s). 6F3387/6H5499. Chemical(s).
Metalaxyl. Requested action(s) Revised Section F for the above petitions to include
20 ppm on tomato pomace and 1.0 ppm on sugar beet molasses.
Document(PDF) (2316 KB PDF).
Attachment(s) Following:
September 26, 1986. Memorandum.
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Cucurbits), Sugar
Beets, and Sugar Beet Tops Evaluation of Analytical Method and Residue Data
(Accession Numbers 262111 and 262111) [RCB Numbers 768 and 769].
February 11, 1987. Memorandum.
Edwin Tinsworth. Registration Division.
Expedited Review for Ciba-Geigy - Metalaxyl on Sugar Beets and Fruiting vegetables.
February 25, 1987. Memo of Telephone conversation.
Robert Quick. Residue Chemistry Branch.
PP#6F3387. Metalaxyl on fruiting vegatables and sugar beets.
February 27, 1987. Memorandum.
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Curcurbits),
Sugar Beets and Sugar Beet Tops. Evaluation of January 30, 1987, Amendment.
(Assession Numbers 400661-1 and 400661-2) [R-C. B #1916].
March 13, 1987. Memorandum.
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Curcurbits),
Sugar Beets and Sugar Beet Tops. Evaluation of February 26, 1987, Amendment.
(No Assession Number) [RCB #I996 and #2013].
March 23, 1987. Memorandum.
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Curcurbits),
Sugar Beets and Sugar Beet Tops. Evaluation of March 6 and 10, 1987, Amendments.
(No Assession Number) [RCB #2037 and #2039].
*End of Attachments*
February 20, 1987. Memorandum. 3 Page(s).
Nancy Dodd. Residue Chemistry Branch.
Screen for Ciba-Geigy Corporation's PP#7H5532 for Metalaxyl (Ridornil®) on Dried Hops.
Document(PDF) (120 KB PDF).
February 25, 1987. Memorandum. 1 Page(s).
Robert Quick. Residue Chemistry Branch.
Memo of Telephone Conversation on February 25, 1987 between Robert Quick, EPA,
and Karen Stumpf, Ciba Geigy Corp PP#6F3387. Metalaxyl on fruiting vegetables
and sugar beets.
Document(PDF) (32 KB PDF).
February 27, 1987. Memorandum. 7 Page(s).
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Curcurbits),
Sugar Beets and Sugar Beet Tops. Evaluation of January 30, 1987, Amendment.
(Accession Numbers 400661-1 and 400661-2) [RCB #1916].
Document(PDF) (263 KB PDF).
March 23, 1987. Memorandum. 9 Page(s).
Francis Griffith. Residue Chemistry Branch.
PP#6F3387/6H5499 Metalaxyl on Fruiting Vegetables (except Curcurbits),
Sugar Beets and Sugar Beet Tops. Evaluation of March 6 and 10, 1987, Amendments.
(No Assession Number) [RCB #2037 and #2039].
Document(PDF) (371 KB PDF).
April 14, 1987. Memorandum. 3 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration No. 7501-42 Gustafson Apron F1 Seed Treatment Fungicide (acute studies)
Accession Number 266162. Page 3 removed, draft label. Tox review 006263.
Document(PDF) (193 KB PDF).
June 22, 1987. Memorandum. 164 Page(s).
Charles Trichilo. Residue Chemistry Branch.
Metalaxyl Registration Standard. (Excerpts) MRID No. 00148440.
Pages 160-164 deleted, manufacturing process-quality control procedures.
Document(PDF) (6037 KB PDF).
July 09, 1987. Memorandum. 38 Page(s).
Stephen Simko. Exposure Assessment Branch.
Metalaxyl Registration Standard (FRSTR).
Pages 25 and 27-38 removed, registrant data.
Document(PDF) (954 KB PDF).
July 16, 1987. Memorandum. 6 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA Registration No 2935-427 (acute toxicity studies...)
Pages 5-6 removed, draft label. Tox review 006152.
Document(PDF) (513 KB PDF).
July 17, 1987. Memorandum. 4 Page(s).
Kyle Barbehenn. Science Integration Staff.
Metalaxyl Registration Standard.
Document(PDF) (130 KB PDF).
July 28, 1987. Memorandum. 14 Page(s).
Nancy Dodd. Residue Chemistry Branch.
FAP#7H5532 (RCB No. 2196) Metalaxyl (Ridomil®) on Hops - Evaluation
of Analytical Method and Residue Data (Accession No. 401626).
Document(PDF) (498 KB PDF).
Attachment(s) Following:
June 25, 1987.
International Residue Limit Status Sheet.
*End of Attachments*
August 05, 1987. Review. 3 Page(s).
Matthew Lorber. Exposure Assessment Branch.
EPA Reg. No 100-601. Ridomol. Additional requested information
on wells from earlier submitted monitoring studies.
Document(PDF) (136 KB PDF).
August 06, 1987. Memorandum. 6 Page(s).
Nancy Dodd. Residue Chemistry Branch.
FAP#7H5532 (RCB #2196). Metalaxyl (Ridomil) on Hops. Addendum to RCB's
7/28/87 Review. (No Accession #). [7/28/87 review is Acc. 401626].
Document(PDF) (167 KB PDF).
August 26, 1987. Memorandum. 4 Page(s).
Nancy Dodd. Residue Chemistry Branch.
FAP#7H5532 (RCB #2688). Metalaxyl (Ridomil) on Hops. Amendment of 8/10/87.
(No Accession #).
Document(PDF) (132 KB PDF).
October 16, 1987. Memorandum. 9 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 7501-REA Gustafson TSX Apron (acute studies...)
MRID 402726-01 thru -06. Pages 7-9 removed, draft label. Tox review 006413.
Document(PDF) (376 KB PDF).
November 17, 1987. Memorandum. 9 Page(s).
Francis B. Suhre. Residue Chemistry Branch.
EPA Reg. No. 100-658: Ridomil (metalaxyl)/Bravo 81W (chlorothalonil) amendment.
MRID No. 201994; RCB No. 2728.
Document(PDF) (362 KB PDF).
February 04, 1988. Review. 3 Page(s).
Paul Schuda. Exposure Assessment Branch.
EPA Reg. No 100-601. Reported metalaxyl findings in ground water.
Document(PDF) (114 KB PDF).
February 16, 1988. Review. 2 Page(s).
Henry Craven. Ecological Effects Branch.
EPA Reg. No 100-607. Submission of bee data for review.
Document(PDF) (195 KB PDF).
Attachment(s) Following:
February 11, 1988. Data Eval. Rec. 3 Page(s).
Norman Cook. Ecological Effects Branch.
Honey bee acute contact LD50. Wildlife International Ltd. Acc. No. 402767-01.
*End of Attachments*
April 12, 1988. Review. 5 Page(s).
Patrick Holden. Exposure Assessment Branch.
Ciba-Geigy Reported metalaxayl findings in ground water.
Document(PDF) (240 KB PDF).
May 09, 1988. Memorandum. 2 Page(s).
Linda Propst. Residue Chemistry Branch.
EPA Reg. No. 100-664. Revised Label for Ridomil PC llG. No MRID No. RCB No. 3706.
Document(PDF) (64 KB PDF).
May 13, 1988. Memorandum. 113 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
PP#7F3470/FAP#7H5520. Metalaxyl in or on Blueberries, Walnuts, Almonds,
Almond Hulls, Stone Fruits, Dried Apricots, and Prunes. MRID Nos. 40503100, -01.
[164649, 164650, 164651 page 46].
Document(PDF) (3039 KB PDF).
Attachment(s) Following:
March 06, 1987. Memorandum.
Maxie Jo Nelson. Residue Chemistry Branch.
PP#7F3470/FAP#7H5520/EPA Reg. No. 100-607. Metalaxyl in or on Blueberries,
Walnuts, Almonds, Almond Hulls, Stone Fruits, Dried Apricots and Prunes.
Evaluation of Analytical Method and Residue Data. [Accession 265762 thru 265765]
[MRID 164649,164650,164651].
July 30, 1987. Review.
Therese Dougherty. Exposure Assessment Branch.
Reg./File 7F3470, 7H5520 and 100-607. Request amendment of label to
add blueberries, stone fruits, walnuts, and almonds (I.D. #100-607).
August 26, 1987. Memorandum.
Maxie Jo Nelson. Residue Chemistry Branch.
PP#7F3470/FAP#7H5520/EPA Reg. No. 100-607. Metalaxyl in or on Prunes.
Blueberries, Walnuts, Almonds, Almond Hulls, Stone Fruits, Dried Apricots
and Review of Amendment of July 15, 1987.
May 18, 1988. Memorandum.
Susan Stanton. Residue Chemistry Branch.
PP#7F347&/7H5520. Tolerance Request For Residues of Metalaxyl in or on
Blueberries, Walnuts, Almonds, stone Fruits, Dried Apricots, and Prunes:
TAS Dietary Exposure Assessment.
September 21, 1989. Memorandum.
Rita Briggs. Science and Coordination Branch HED.
Dietary Exposure Analysis for the Proposed Use of Metalaxyl in or on
Blueberries, Walnuts, Almonds, Almond Hulls, Stone Fruits, Dried Apricots,
and Prunes, PP#7F3470 and FAP#7H5520.
*End of Attachments*
May 13, 1988. Memorandum. 6 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
PP# 7F3470/FAP# 7H5520. Metalaxyl in or on Blueberries, Walnuts, Almonds,
Almond Hulls, Stone Fruits, Dried Apricots, and Prunes. MRID 405031-00, -01.
Document(PDF) (278 KB PDF).
May 25, 1988. Memorandum. 2 Page(s).
Linda Propst. Residue Chemistry Branch.
EPA Reg. No. 100-628. Ridomil 5G (metalaxyl). Amended registration request to
add use on tomatoes. No MRID No. RCB No. 3741.
Document(PDF) (83 KB PDF).
May 31, 1988. Review. 2 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Reg. No. 100-607 New use on blueberries, stone fruits, walnuts and almonds.
Document(PDF) (66 KB PDF).
June 17, 1988. Memorandum. 1 Page(s).
Catherine Eiden. Exposure Assessment Branch.
Metalaxyl registration on Blueberries, Stone Fruits, and Walnuts and Almonds.
Document(PDF) (53 KB PDF).
August 17, 1988. Review. 2 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Reg. No. 100-607, 628, 629 Review new label.
Document(PDF) (68 KB PDF).
November 17, 1988. Memorandum. 2 Page(s).
Stephanie Willett. Dietary Exposure Branch.
FAP#7H5532. Metalaxyl (Ridomil) on Hops. Revised Section B and F.
DEB No. 4630. No MRID Number.
Document(PDF) (68 KB PDF).
November 22, 1988. Memorandum. 2 Page(s).
William Anthony. Dietary Exposure Branch.
EPA Reg. #100-639. [RCB #4219] [MRID: None} possible use of excess corn seed
treated with metalaxyl for use as feed for beef and dairy cattle.
Document(PDF) (71 KB PDF).
February 09, 1989. Memorandum. 3 Page(s).
Linda Propst. Dietary Exposure Branch.
EPA Reg. No. 100-628. Ridomil 5G (metalaxyl). Amended registration request to add
use on head lettuce. MRID No. 40775801. DEB No. 4808.
Document(PDF) (106 KB PDF).
February 14, 1989. Memorandum. 3 Page(s).
Linda Propst. Dietary Exposure Branch.
EPA Reg. No. 100 628. Ridomil 5G (metalaxyl). Amended registration request to add
use on spinach. MRID No. 407902-01. DEB NO. 4809.
Document(PDF) (88 KB PDF).
April 11, 1989. Memorandum. 7 Page(s).
Stephanie Willett. Dietary Exposure Branch.
PP# 9F3712. Metalaxyl on Green Hops. Petition to Revise Tolerance.
MRID# 409094-01. DEB Nos. 4811, 4812, 4813.
Document(PDF) (230 KB PDF).
May 03, 1989. Review. 5 Page(s).
Patrick Holden. Environmental Fate & Ground Water Branch.
Review proposed protocol for small-scale retrospective ground-water monitoring study.
Document(PDF) (534 KB PDF).
May 10, 1989. Memorandum. 11 Page(s).
Martin Kovacs. Dietary Exposure Branch.
PF#6F3337 - Metalaxyl on Strawberries - Evaluation of Amendment Dated November 4, 1988
(MRID Nos. 40880400 and 40880401) (DEB Nos. 4814, 4815, and 4816).
Document(PDF) (346 KB PDF).
May 24, 1989. Review. 11 Page(s).
Patrick Holden. Environmental Fate & Ground Water Branch.
Metalaxyl. Review Proposed Protocol for Small-Scale Retrospective Ground Water
Monitoring Study.
Document(PDF) (622 KB PDF).
August 03, 1989. Memorandum. 12 Page(s).
Joel Garbus. Dietary Exposure Branch.
PP#8F3698: Metalaxyl: Tolerances for Metalaxyl for the Crop Grouping Root
and Tuber Vegetables. Evaluation of Residue Data and Analytical Methodology.
MRID Nos. 40838301 to 40838303; DEB Nos. 4788 to 4791.
Document(PDF) (447 KB PDF).
August 08, 1989. Memorandum. 8 Page(s).
Joel Garbus. Dietary Exposure Branch.
PP's# 8F3695/8H5569: Metalaxyl Tolerances for Alfalfa and for Barley as Rotational
Crop. Evaluation of Residue Data and Analytical Methodology. MRID No. 408329-01.
DEB Nos.4792, 4793, and 4794.
Document(PDF) (282 KB PDF).
September 07, 1989. Review. 9 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg. No 100-628 Review data submitted in response to Registration standard.
(photodegradation in water) Pages 7-9 removed-registrant data. MRID 41156001.
Document(PDF) (299 KB PDF).
September 29, 1989. Review. 4 Page(s).
Clyde Houseknecht. Ecological Effects Branch.
Reg. No 100-601, 607 PP# 8F3695, 8H5569 Proposed registration of use on alfalfa.
Document(PDF) (215 KB PDF).
October 12, 1989. Review. 5 Page(s).
Clyde Houseknecht. Ecological Effects Branch.
Reg. No 100-601, 607, 629 PP# 9F3698 Proposed registration of use on root and tuber
crops (Ridomil 2E) and Carrots (Ridomil MZ58).
Document(PDF) (264 KB PDF).
October 23, 1989. Memorandum. 4 Page(s).
Joel Garbus. Dietary Exposure Branch.
PP#9F3698: [Formerly PP#8F3698]: Metalaxyl: Tolerances for the Crop Grouping:
Root and Tuber Vegetables. Amendment of September 15, 1989. Revised Sections B
and F for PP#8F3698. No MRID No. DEB No. 5836.
Document(PDF) (140 KB PDF).
October 30, 1989. Review. 12 Page(s).
Thomas Dixon. Environmental Fate & Ground Water Branch.
Reg. No 100-607 Review of groundwater monitoring study (potable water supplies).
Document(PDF) (492 KB PDF).
November 02, 1989. Memorandum. 2 Page(s).
Debra Edwards. Dietary Exposure Branch.
PP#6F3337 - Metalaxyl on Strawberries. Amendment of 9/27/89.
Document(PDF) (51 KB PDF).
December 04, 1989. Memorandum. 4 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg. No./File Symbol 2935-ULI Wilbur-Ellis Apron TL MRID 405714-02.
(acute inhalation study). Tox review 008908. Page 4 removed, draft product label data.
Document(PDF) (189 KB PDF).
December 05, 1989. Memorandum. 2 Page(s).
Francis Suhre. Dietary Exposure Branch.
Metalaxyl. EPA Reg. No. 100-607 (Ridomil 2E Fungicide). EPA Reg. No. 100-628
(Ridomil 5G Fungicide). A rotational crop residue study protocol entitled,
"Ridomil Double Cropping Program." No MRIDs.
Document(PDF) (60 KB PDF).
December 11, 1989. Memorandum. 31 Page(s).
Gary Otakie. Dietary Exposure Branch.
PP #6F3362/FAP #6H5493 - Metalaxyl and Mancozeb on Grapes (DEB Nos. 5557 and 5558).
Evaluation of Amendment Dated June 23, 1989 (MRID No. 411501-01).
Pages 22-30 removed, registrant data.
Document(PDF) (1572 KB PDF).
February 14, 1990. Memorandum. 33 Page(s).
Joel Garbus. Dietary Exposure Branch.
PP#8F3698: Metalaxyl: Tolerances for the Crop Grouping: Root and Tuber Vegetables.
Amendment of December 7, 1989. Revised Section B. No MRID No. DEB No. 6176.
Document(PDF) (793 KB PDF).
Attachment(s) Following:
July 31, 1989.
INTERNATIONAL RESIDUE LIMIT STATUS. Chemical Metalaxyl.
August 03, 1989. Memorandum.
Joel Garbus. Dietary Exposure Branch.
PP#8F3698: Metalaxyl: Tolerances for Metalaxyl for the Crop Grouping Root
and Tuber Vegetables. Evaluation of Residue Data and Analytical Methodology.
MRID Nos. 408383-01 to 408383-03: DEB Nos.4788 to 4791.
September 15, 1989.
Ciba-Geigy Corporation..
VOLUME 1 OF 1. TECHNICAL METALAXYL. EPA REG. NO. 100-601.
PESTICIDE PETITION 9F3698. REQUEST FOR TOLERANCES IN THE ROOT AND
TUBER VEGETABLE CROP GROUPING. CONTENTS: REVISED SECTIONS B AND F.
October 23, 1989. Memorandum.
Joel Garbus. Dietary Exposure Branch.
PP#9F3698: [Formerly PP#8F3698]: Metalaxyl: Tolerances for the Crop
Grouping: Root and Tuber Vegetables. Amendment of September 15, 1989.
Revised Sections B and F for PP#8F3698. No MRID No. DEB No.5836.
December 07, 1989.
Ciba-Geigy Corporation.
VOLUME 1 OF 1. TECHNICAL METALAXYL. EPA REG. NO. 100-601.
PESTICIDE PETITION 8F3698. REQUEST FOR TOLERANCES IN THE ROOT
AND TUBER VEGETABLE CROP GROUPING. CONTENTS: REVISED SECTION B.
*End of Attachments*
March 05, 1990. Memorandum. 6 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg. No./File Symbol 100-601 Metalaxyl Technical Acute eye irritation.
MRID 00084108. Tox review 009279.
Document(PDF) (345 KB PDF).
March 06, 1990. Review. 5 Page(s).
Allen Vaughan. Ecological Effects Branch.
Reg. No 100-601, 100-607 PP# 9F3712 Proposed label amendment expanding use
on hops to include foliar applications.
Document(PDF) (252 KB PDF).
March 13, 1990. Memorandum. 4 Page(s).
Joel Garbus. Dietary Exposure Branch.
PP # 8F3695/8H5569: Metalaxyl: Tolerances for Alfalfa and for Barley as Rotational
Crop. Amendment of September 1, 1989. Revised Sections B and F. No MRID No.
DEB Nos.6347 and 6348.
Document(PDF) (102 KB PDF).
March 28, 1990. Review. 3 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg./File 100-628. Review correspondence related to progress report on multicropping
with metalaxyl.
Document(PDF) (322 KB PDF).
April 25, 1990. Letter. 2 Page(s).
Francis D. Griffith. Dietary Exposure Branch.
Multiresidue Method (MRM) test information for updating a future addition of PAM-I,
Appendix 1. MRID No. 410552-03.
Document(PDF) (127 KB PDF).
April 30, 1990. Memorandum. 13 Page(s).
Francis D. Griffith. Dietary Exposure Branch.
PP#8F3617/8H5554 - Metalaxyl on Sugar Beet Tops and Roots, Legume Vegetables
(Dry and Succulent) Crop Group: Legume vegetables Foliage Crop Group; … Animal
Feeds Crop Group. Evaluation of the September 21, 1989 Amendment.
MRID Nos. 412501-01, 410552-03.
Document(PDF) (475 KB PDF).
May 14, 1990. Review. 126 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
New use on alfalfa, root and tuber vegetable crop groupings, and carrots...
MRID 40985401, 40985402, 40985403, 40985404.
Commercial/financial info on pages 4, 11 not included.
Pages 21-37, 45-61, 68-90, 97-119, 123-126 removed, registrant data.
Document(PDF) (2899 KB PDF).
May 24, 1990. Letter. 1 Page(s).
Michael Flood. Dietary Exposure Branch.
Your letter of April 30, EPA recently established a food additive tolerance for
metalaxyl in/on dried apricots. The registrant, Ciba-Geigy Corporation, requested
this tolerance in PP#7F3470/FAP#7H5520.
Document(PDF) (29 KB PDF).
July 05, 1990. Memorandum. 67 Page(s).
Rita Briggs. Science Analysis & Coordination Branch.
Dietary Exposure Analysis for the Proposed Use of Metalaxyl on Sugar Beet Tops
and Roots, PP#8F3617/8H5554.
Document(PDF) (2328 KB PDF).
Attachment(s) Following:
November 28, 1988. Memorandum.
Francis Griffith. Dietary Exposure Branch.
(continued) Evaluation of Analytical Methods and Residue Data
(MRID No. 405348-00 through -03 and 405693-01 through -03) [DEB Nos. 3908 through 3912].
November 28, 1988. Memorandum.
Francis Griffith. Dietary Exposure Branch.
PP#8F3617/8H5554 - Metalaxyl on Sugar Beet Tops and Roots; Legume Vegetables
(Dry and Succulent) Crop Groups; Legume Vegetables Foliage Crop Group; Grass
Forage, Fodder, and Hay Crop Group; and Nongrass Animal Feeds Crop Group.
April 14, 1989. Letter.
Karen Stumpf. Ciba-Geigy.
Letter to Susan Lewis, EPA. Metalaxyl registration Standard.
EPA Policy Regarding the Expansion of Metalaxyl Labels During
the Course of Reregistration.
April 25, 1990. Letter.
Francis Griffith. Dietary Exposure Branch.
Letter to Leon Sawyer, FDA. Enclosed is the Multiresidue Method
(MRM) test information for... PAM-I.
April 30, 1990. Memorandum.
Francis Griffith. Dietary Exposure Branch.
(continued) Evaluation of the Septembr 21, 1989 Amendment.
(MRID Nos. 412501-01 and 410552-03) [DEB Nos. 5934, 5935, and 6545)
[HED Nos. 0-0044 and 1010].
April 30, 1990. Memorandum.
Francis Griffith. Dietary Exposure Branch.
PP#8F3617/8H5554 - Metalaxyl on Sugar Beet Tops and Roots, Legume Vegetables
(Dry and Succulent) Crop Group; Legume Vegetables Foliage Crop Group; Grass
Forage, Fodder, and Hay Crop Group; and Non-grass Animal Feeds Crop Group.
*End of Attachments*
July 24, 1990. Memorandum. 2 Page(s).
Richard Loranger. Dietary Exposure Branch.
Summary of telephone calls from Ciba Geigy: (1) Metolachlor on small grains,
(2) Metalaxyl-new formulation.
Document(PDF) (126 KB PDF).
January 02, 1991. Review. 3 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No 100-607 Review to amend the registration on hops.
Document(PDF) (117 KB PDF).
January 15, 1991. Memorandum. 15 Page(s).
R. B. Perfetti. Chemistry Branch II.
Ciba-Geigy Corp.: Response to the Metalaxyl Reregistration Standard:
Storage Stability and Sample Histories and Multiresidue Protocol Data
(MRID# 41449001, 41055203 and 40534803).
Document(PDF) (530 KB PDF).
January 28, 1991. Memorandum. 3 Page(s).
Donald Stubbs. Registration Support Branch.
An Expidite Product Chemistry Review Section on Metalaxyl Technical.
EPA Reg. No.: 100-601.
Document(PDF) (116 KB PDF).
February 19, 1991. Memorandum. 2 Page(s).
Kenneth Dockter. Chemistry Branch II.
EPA Reg. No. 100-628. Ridomil 5G [metalaxyl] add use on spinach.
Additional residue studies submitted 9/19/90 in response to DEB 2/14/89 review.
MRID 416362-01; D156892. CBRS 7165.
Document(PDF) (65 KB PDF).
February 19, 1991. Review. 24 Page(s).
James Akerman. Ecological Effects Branch.
Reviews of estuarine/marine studies Acc. No. 4128810-01, 02, 03, 04.
Pages 7, 17 and 23 removed, registrant data.
Document(PDF) (1209 KB PDF).
February 22, 1991. Memorandum. 10 Page(s).
Gary Otakie. Chemistry Branch.
Petition Review for Establishment of Tolerances. Evaluation of Analytical
Methods and Residue Data. PP#1E3926. MRID 41688901.
Document(PDF) (301 KB PDF).
March 13, 1991. Memorandum. 72 Page(s).
Edward Zager. Chemistry Branch.
Metalaxyl Product Chemistry and Residue Chemistry Reregistration Standard
Updates. Pages 14-23 removed, manufacturing process, quality control and inert
ingredient information. MRID 41055201, 41055202.
Document(PDF) (2478 KB PDF).
March 25, 1991. Review. 3 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No 100-601, -607 Metalaxyl Technical/ Ridomil 2E Fungicide.
Document(PDF) (151 KB PDF).
April 08, 1991. Memorandum. 2 Page(s).
Gary Otakie. Chemistry Branch.
PP#1E3926 - Metalaxyl of Ginseng - Amendment of March 21, 1991 (DEB No. 7787).
Document(PDF) (51 KB PDF).
April 15, 1991. Memorandum. 2 Page(s).
Kenneth Dockter. Chemistry Branch.
EPA Reg. No. 100-639. Apron 25W Fungicide [metalaxyl] over-tolerance residues
in sorghum seed treatment study. No MRID; D162911. CBRS 7841.
Document(PDF) (50 KB PDF).
May 10, 1991. Memorandum. 2 Page(s).
Nguyen Thoa. Toxicology Branch I.
Metalaxyl N-(2,6,-dimethylphenyl)-N-(methoxacetyl)- alanine, methyl ester:
Company Response (acute inhalation in rats). Tox review 008364.
Document(PDF) (238 KB PDF).
May 13, 1991. Memorandum. 2 Page(s).
Christina Swartz. Chemistry Branch.
Metalaxyl/IN900001. Resubmission for Section 24 (c) registration of Ridomil 5G
on cucurbits. DEB No. 7788. Barcode No. D162783. MRID Nos. 40790201 and 41636201.
Document(PDF) (75 KB PDF).
May 16, 1991. Memorandum. 6 Page(s).
James Akerman. Ecological Effects Branch.
List A DCI Review Package for Metalaxyl (Sh. #113501).
Document(PDF) (190 KB PDF).
June 17, 1991. Memorandum. 2 Page(s).
George Tompkins. Environmental Fate & Ground Water Branch.
Environmental Fate Studies to be Included in the Data Call In Notice for Metalaxyl (113501).
Document(PDF) (98 KB PDF).
June 21, 1991. Memorandum. 15 Page(s).
Shanaz Bacchus. Chemistry Branch I.
PP#0F3893 (EPA Reg. Nos. 100-607, 100-608): Metalaxyl Technical: (Ridomil 2E).
Tolerance In/On Leafy Vegetables (Excluding Brassica Vegetables, Excluding
Spinach). Analysis of Residue Data and Analytical Method...
MRIDs: 415878-00, 415878-01. DP # 156811.
Document(PDF) (539 KB PDF).
August 26, 1991. Memorandum. 12 Page(s).
Douglas Urban. Ecological Effects Branch.
Request to Upgrade Three Acute Toxicity Tests for Estuarine and Marine
Organisms for Metalaxyl (Chemical No. 113501).
Document(PDF) (586 KB PDF).
September 09, 1991. Review. 14 Page(s).
Gary F. Otakie. P.E. Chemistry Branch I, Health Effects Div.
PP# 8F3362/FAP# 6H5493 - Metalaxyl on Grapes (CB-1 Nos. 7646 and 7647)
-Evaluation of Amendment Dated January 25, 1991 MRID Nos. 41664503 thru 41664506).
Document(PDF) (726 KB PDF).
October 31, 1991. Memorandum. 9 Page(s).
Jose J. Morales. Chemistry Branch I.
PP#1E4024. Metalaxyl on cranberries. Evaluation of residue data and analytical
methodology. MRID # 419964-01. CBTS # 8582. DP Barcode D168812. HED # 1-2396.
Document(PDF) (302 KB PDF).
December 12, 1991. Memorandum. 5 Page(s).
Kenneth Dockter. Chemistry Branch.
Id# 100-TEN. Ridomil/Copper 70W Fungicide [metalaxyl/copper hydroxide] "Me Too".
For Foliar Use on Carrots, Cucurbits, Peppers, Potatoes, Radishes, Spinach, and
Tomatoes. Accession Nos. 251021 and 262112 [mrid 157478, 157480], and
MRID 417183-01; D169183.
Document(PDF) (232 KB PDF).
December 18, 1991. Memorandum. 7 Page(s).
Robert Lascola. Chemistry Branch.
PP#F3893: Metalaxyl (Ridomil 2E, 5G) in/on Leafy Vegetables
(Excluding Brassica, Excluding Spinach). Amendment of 9/9/91 CBTS# 8898.
MRID# 420211-01. DP Barcode# D171050.
Document(PDF) (338 KB PDF).
January 22, 1992. Memorandum. 2 Page(s).
John Abbotts. Chemistry Branch II.
Meeting with Ciba-Geigy on Proposed Amendment to Feed Seed Treated with Metalaxyl.
No MRID No.
Document(PDF) (83 KB PDF).
January 22, 1992. Memorandum. 3 Page(s).
William Smith. Chemistry Branch.
Metalaxyl Reregistration: Ciba-Geigy Corporation Request for Concurrence with
Storage Stability Protocol. CBRS No. 8723. No MRIDs. DP Barcode D169714.
Document(PDF) (83 KB PDF).
January 24, 1992. Review. 4 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review of the detections of metalaxyl and simazine in ground water in Washington
405 Adverse 6(a)(2).
Document(PDF) (560 KB PDF).
February 27, 1992. Memorandum. 2 Page(s).
Roger Gardner. Toxicology Branch I.
Metalaxyl Technical (EPA Reg. No. 100-601): New CSF and Label.
Manufacturing process information on pages 1-2 is not included.
Document(PDF) (99 KB PDF).
March 04, 1992. Memorandum. 15 Page(s).
Lucy Markarian. Registration Support Branch.
EPA File Symbol/EPA Reg. No.: 100-TGL Acute toxicity studies.
MRID 420520-03 thru -09. Tox review 010104.
Document(PDF) (899 KB PDF).
March 06, 1992. Memorandum. 27 Page(s).
W. T. Chin. Chemistry Branch Tolerance Support.
ID #000100-00607 and #000100-00628: Amended Registration of Metalaxyl
in/on Ginseng (MRID #416889-00, #416889-01, CBTS #9054 and #9058).
Document(PDF) (816 KB PDF).
Attachment(s) Following:
February 22, 1991. Memorandum.
Gary Otakie. Chemistry Branch I.
Petition Review for Establishment of Tolerance(s).
Evaluation of Analytical Method( s) and Residue Data.
February 28, 1991. Letter.
This is in reference to the subject petition proposing establishment of a tolerance
for residues of the fungicide metalaxyl in or on the raw agricultural commodity
ginseng root (fresh) at 3.0 ppm.
April 08, 1991. Memorandum.
Gary Otakie. Chemistry Branch I.
PP#1E3926 - Metalaxyl on Ginseng - Amendment of March 21, 1991 (DEB-NO. 7787).
*End of Attachments*
March 06, 1992. Memorandum. 4 Page(s).
W. T. Chin. Chemistry Branch Tolerance Support.
ID #000100-00607 and #000100-00628: Amended Registration of Metalaxyl
in/on Ginseng (MRID #416889-00, #416889-01, CBTS #9054 and #9058).
Document(PDF) (133 KB PDF).
March 16, 1992. Memorandum. 2 Page(s).
Susan Lewis. Fungicide Herbicide Branch.
Metalaxyl Technical New CSF and Label EPA File Symbol 100-601 Your Submission
Dated January 9, 1991. Manufacturing process information on page 1 is not included.
Document(PDF) (80 KB PDF).
April 15, 1992. Review. 5 Page(s).
Richard Felthousen. Ecological Effects Branch.
Purpose of Submission The Massachusetts Department of Food and Agriculture
(MDFA) has submitted a request for a Section 18 Specific Exemption.
Document(PDF) (261 KB PDF).
April 15, 1992. Review. 5 Page(s).
Richard Felthousen. Ecological Effects Branch.
Purpose of Submission The State of New Jersey Department of Environmental Protection
and Energy (NJDEPE) has submitted a request for a Section 18 Specific Exemption.
Document(PDF) (249 KB PDF).
April 16, 1992. Memorandum. 29 Page(s).
John Abbotts. Chemistry Branch II.
Metalaxyl. Ciba-Geigy Response to the Reregistration Standard: Product Chemistry
Data , Storage Interval Data, & Corn Fodder Data. MRID Nos. 41912901 -02 & -03.
Pages 16-20 deleted, MP-QCP.
Document(PDF) (829 KB PDF).
May 12, 1992. Memorandum. 2 Page(s).
Robert Lascola. Chemistry Branch I.
PP#0F3893. Metalaxyl (Ridormil 2E, 5G) in/on Leafy Vegetables
(Excluding Brassica, Excluding Spinach). Amendment of 3/17/92.
CBTS# 9710. No MRID#. DP Barcode# D176810.
Document(PDF) (68 KB PDF).
May 27, 1992. Review. 3 Page(s).
Douglas Urban. Ecological Effects Branch.
Texas Dept. of Agriculture Proposed Sec. 18 for use on roses.
Document(PDF) (190 KB PDF).
June 01, 1992. Memorandum. 17 Page(s).
Leung Cheng. Chemistry Branch II, Health Effects Div.
Metlaxyl. Ciba-Geigy Response to Guidance Document (FRSTR) Dated 9/88.
MRID# 418703-01 through -07. CBRS# 8043. DP Barcode: D164655.
Document(PDF) (1222 KB PDF).
June 04, 1992. Memorandum. 3 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Requirement for Retrospective Ground-Water Monitoring Studies for Metalaxyl.
Document(PDF) (207 KB PDF).
June 08, 1992. Memorandum. 10 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Report Possible Adverse Pesticide Residue Data Ciba-Geigy.
Document(PDF) (655 KB PDF).
June 19, 1992. Memorandum. 2 Page(s).
Jose J. Morales. Chemistry Branch I.
PP#1F3993. Metalaxyl. Tolerance petition for residues in cereal grains,
soybeans, potatoes, peanuts, cottonseed, sunflower seed, and hops.
Evaluation of residue data and analytical methodology. DP Barcode D169779,
MRID Nos. 418703-01,02,03,04,05,06,07,08.
Document(PDF) (58 KB PDF).
June 22, 1992. Memorandum. 8 Page(s).
R. B. Perfetti. Chemistry Branch.
Ciba-Geigy Corp.: Response to the Metalazxyl Reregistration Standard:
Residue and Processing Data (MRID # 42233501, CBRS # 9596, Barcode D175852.).
Document(PDF) (307 KB PDF).
June 24, 1992. Memorandum. 8 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review 6(a)(2) Adverse Pesticide Residue Data Ciba-Geigy.
Document(PDF) (377 KB PDF).
July 17, 1992. Memorandum. 2 Page(s).
Jose J. Morales. Chemistry Branch I.
PP#1E4024. Metalaxyl on cranberries. Amendment to review of 10/31/91.
DB Barcode No. D175506. HED# 2-1679. CBTS# 9537. MRID # none.
Document(PDF) (68 KB PDF).
September 23, 1992. Memorandum. 2 Page(s).
Richard Mahler. Environmental Fate & Ground Water Branch.
CIBA-GEIGY is Requesting a Data Waiver for the Field Accumulation in
Rotational Crops (165-2) Study for Metalaxyl.
Document(PDF) (78 KB PDF).
September 30, 1992. Review. 2 Page(s).
Douglas Urban. Ecological Effects Branch.
CIBA-GEIGY CORP. Amend grain crops to cereal crops.
Document(PDF) (78 KB PDF).
September 30, 1992. Review. 8 Page(s).
Dana Lateulere. Environmental Fate & Ground Water Branch.
CIBA-GEIGY Add use on ginseng.
Document(PDF) (311 KB PDF).
October 02, 1992. Review. 6 Page(s).
Dana Lateulere. Ecological Effects Branch.
CIBA-GEIGY CORP. Add use on brassica (cole) leafy vegetable crops to label.
Document(PDF) (287 KB PDF).
November 24, 1992. Memorandum. 4 Page(s).
Leung Cheng. Chemistry Branch.
Metalaxyl. Label Amendments for Peanuts. CBRS # 10743 & 10744.
DP Barcode: D183657 & D183659.
Document(PDF) (184 KB PDF).
January 15, 1993. Memorandum. 12 Page(s).
Mary Peters. Chemistry Branch I-Tolerance Support.
PP# 2F04072: 1. Metalaxyl (Ridomil® 2E Fungicide, EPA Reg. No. 100-607) in or on
members of the Brassica (cole) leafy vegetables crop grouping; evaluation of request
for amended registration, analytical method and residue data of mustard greens.
Document(PDF) (479 KB PDF).
Attachment(s) Following:
August 27, 1992.
International Residue Limit Status Sheet.
*End of Attachments*
March 15, 1993. Review. 22 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Regulatory options for metalaxyl and waiver of requiremnet for retrospective
ground-water monitoring studies.
Document(PDF) (1334 KB PDF).
March 16, 1993. Memorandum. 2 Page(s).
John Abbotts. Chemistry Branch II.
Meeting with Ciba-Geigy, 3/10/93, on Proposed Amendment to Feed Seed Treated
with Metalaxyl.
Document(PDF) (74 KB PDF).
March 22, 1993. memorandum. 3 Page(s).
Richard Mahler. Environmental Fate & Ground Water Branch.
Section 18 Emergency Use of Pace Fungicide for the Control of Peronospora sparsa
(downy mildew on roses). DP Barcode: D177213.
Document(PDF) (224 KB PDF).
April 14, 1993. Memorandum. 27 Page(s).
Nguyen Thoa. Chemical Coordination Branch.
Metabolism study with Metalaxyl (GL 85-1) MRID 416645-01.
Pages 18-27 removed, registrant data. Tox review 010164.
Document(PDF) (1074 KB PDF).
May 05, 1993. Memorandum. 6 Page(s).
Francis D. Griffith. Chemistry Branch I.
LA-920004 METALAXYL( RIDOMIL®)- SPECIAL LOCAL NEED [24 (c)]
REGISTRATION AND AMENDED USE REGISTRATION FOR EPA REGISTRATION
NUMBER 100-607 (RIDOMIL® 2E FUNGICIDE) ON WATER SEEDED RICE...
(MRID# 42259805) {DP Barcode#s D189772 and D189764}.
Document(PDF) (273 KB PDF).
May 11, 1993. Data Eval Rec. 38 Page(s).
Richard J. Mahler. Environmental Fate & Ground Water Branch.
Study 7. MRID 422598-04. Aquatic dissipation study for water seeded rice...
Pages 6-38 removed, registrant data.
Document(PDF) (371 KB PDF).
May 11, 1993. Data Eval Rec. 42 Page(s).
Richard J. Mahler. Environmental Fate & Ground Water Branch.
Study 6. MRID 422598-03. Aquatic dissipation of metalaxyl (Ridomil 2E)...
Pages 5-42 removed, registrant data.
Document(PDF) (322 KB PDF).
May 11, 1993. Review. 7 Page(s).
Richard Mahler. Environmental Fate & Ground Water Branch.
Study 4. Terrestrial Field Dissipation. 164-1. Pages 7-43 removed, registrant data.
MRID 41809301.
Document(PDF) (825 KB PDF).
May 13, 1993. Review. 371 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Review questions related to field dissipation studies, rotational restriction,
tolerances, amendments, aerobic and anaerobic aquatic and field dissipation studies.
Pages 30-50, 56-71, 79-146, 153-189, 199-239, 245-281, 288-318, 324-367 removed-registrant.
Document(PDF) (1084 KB PDF).
Attachment(s) Following:
May 13, 1993. Review.
Paul Mastradone. Environmental Fate & Ground Water Branch.
(continued) MRIDs 42259801, 42259802, 41765001, 41809301,
41765002, 42259803, 42259804, 42196501.
*End of Attachments*
June 28, 1993. Review. 23 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
ID# 92WI0004 Section 18 Exemption - determine if exemption would cause
ground-water concerns.
Document(PDF) (1225 KB PDF).
July 22, 1993. Memorandum. 15 Page(s).
John Abbotts. Chemistry Branch II.
Metalaxyl, Reregistration. Registrant Ciba-Geigy Submission on Magnitude of the
Residue in Peanuts and Processed Commodities of Rice, Sunflower, and Pineapple
(MRID Nos. 42498701, 42498702). CBRS No. 11238. DP Barcode No. D187081.
Document(PDF) (363 KB PDF).
Attachment(s) Following:
April 22, 1993. Review.
Acurex Environmental Corporation.
METALAXYL. (Chemical Code 113501). (CERS No. 11238; DP Barcode D187081).
TASK 3. Registrant's Response to Residue Chemistry Data Requirements.
*End of Attachments*
August 09, 1993. Oneliner. 6 Page(s).
Environmental Fate and Ground Water Branch.
Pesticide Environmental Fate One Line Summary Metalaxyl.
Document(PDF) (322 KB PDF).
August 17, 1993. Memorandum. 16 Page(s).
Maria Isabel Rodriguez. Chemistry Branch I.
ID # PP2F4105: Metalaxyl (Ridomil 2E) in or on Non-grass Animal Feeds (as Clover).
Evaluation of Analytical and Residue Data. CBTS # 9625. HED # 2-1840. EPA Reg. #100607.
DP Baroode # D175974. MRID # 422268-01.
Document(PDF) (476 KB PDF).
September 10, 1993. Memorandum. 19 Page(s).
Susan V. Hummel. Chemistry Branch II.
Metalaxyl (113501) Ruminant and Poultry Metabolism: HED Metabolism Committee
Meeting Held September 8, 1993.
Document(PDF) (473 KB PDF).
September 15, 1993. Memorandum. 26 Page(s).
Susan V. Hummel. Chemistry Branch II.
Metalaxyl (113501) Additiod Ruminant and Poultry Metabolism Data Poultry
Feeding Study [MRID Nos. 42115801 to -10; CB No. 9102; DP Barcode D172350].
Document(PDF) (907 KB PDF).
Attachment(s) Following:
September 15, 1993. Review.
Acurex Environmental Corporation.
METALAXYL. (Chemical Code 113501). (CBRS No. 9102; DP Barcode D172350).
TASK 3. Registrant's Response to Residue Chemistry Data Requirements.
*End of Attachments*
September 22, 1993. Memorandum. 10 Page(s).
Mary Peters. Chemistry Branch I-Tolerance Support.
PP# 2F04063, Metalaxyl in or on the grass forage, fodder, and hay crop grouping.
Evaluation of analytical method and residue data (Ridornil® 2E Fungicide, EPA Reg
No. 100-607). CBTS# 9338, HED# 2-1271, DP Barcode D173024, MRID# 421345-00, -01.
Document(PDF) (459 KB PDF).
September 30, 1993. Memorandum. 2 Page(s).
David Miller. Reregistration Support Section II.
PP#1F3993. EPA Reg. No. 100-601. September 30, 1992. Letter to OPP
from Ciba-Geigy re:proposed METALAXYL tolerances. CBRS #: 10833.
DP Barcode #: D183914. MRID #: None.
Document(PDF) (54 KB PDF).
September 30, 1993. Memorandum. 33 Page(s).
David Miller. Reregistration Support Section II.
PP#1F3993. EPA Reg. NO. 100-601. September 30, 1992 Letter to OPP
from Ciba-Geigy re:proposed METALAXYL tolerances. CBRS #: 10833.
DP Barcode #: D183914. MRID #: None.
Document(PDF) (1095 KB PDF).
Attachment(s) Following:
Ciba-Geigy Corporation.
VOLUME 1 OF 1 OF SUBMISSION. TECHNICAL METALAXYL.
EPA REG. NO. 100-601. PESTICIDE PETITION 1F3993. CONTENTS -REVISED SECTION F.
June 01, 1992. Memorandum.
Leung Cheng. Chemistry Branch II.
Metalaxyl. Ciba-Geigy Response to Guidance Document (FRSTR) Dated 9/88.
MRID # 418703-01 through -07. CBRS # 8043. DP Barcode: D164655.
June 19, 1992. Memorandum.
Jose J. Morales. Chemistry Branch I.
PP#1F3993. Metalaxyl. Tolerance petition for residues in cereal grains,
soybeans, potatoes, peanuts, cottonseed, sunflower seed, and hops...
CBTS # 9011. HED # 2-0630. DP Barcode D169779.
MRID #'s 418703-01, -02, -03, -04, -05, -06, -07, -08.
September 30, 1992. Letter.
Karen Stumpf. Ciba-Geigy.
Technical Metalaxyl - EPA Reg. No. 100-601. Ridomil 2E fungicide -
EPA Reg. No. 100-607. Ridomil MZ 58 Fungicide - EPA Reg. No. 100-629.
Pesticide Petition 1F3993 Cereal grains. Submission of revised section F.
*End of Attachments*
November 01, 1993. Memorandum. 4 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Estuarine TEP Testing for Metalaxyl, D180647 and D179489.
[cover with review summary; reviews not included] Mysid shrimp; Eastern oyster.
MRIDs 42337501, 42378101.
Document(PDF) (409 KB PDF).
November 02, 1993. Review. 29 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Review Oyster Deposition Study, data gaps? Review Acute Mysid with TEP.
Pages 10-11, 26-27 removed, registrant data MRID 42378101, 42337501.
Document(PDF) (1263 KB PDF).
February 17, 1994. Memorandum. 9 Page(s).
Susan Hummel. Chemistry Branch II.
Metalaxyl (113501). Storage Stability Data Interim Report. MRID No. 42919401.
Document(PDF) (548 KB PDF).
February 17, 1994. Review. 8 Page(s).
Susan V. Hummel. Chemistry Branch II.
Metalaxyl (113501) Storage Stability Data Interim Report MRID 42919401.
Document(PDF) (564 KB PDF).
February 21, 1994. Review. 22 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Prepare EFGWB Science Chapter for Metalaxyl RED. DP Barcode: D197035.
Document(PDF) (1190 KB PDF).
April 19, 1994. Memorandum. 17 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Ecological Effects Branch Chapter for Metalaxyl (Shaughnessy # 113501)
for Registration Eligibility Document (D197034).
Document(PDF) (880 KB PDF).
April 20, 1994. Memorandum. 6 Page(s).
George Z. Ghali. Quality Assurance Peer Review.
RfD/Peer Review Report of Metalaxyl.
Document(PDF) (309 KB PDF).
June 16, 1994. Memorandum. 105 Page(s).
Susan Hummel. Chemistry Branch.
Metalaxyl (113501) -Case No. 0081. Product and Residue Chemistry Chapters for the
Reregistration Eligibility Document (RED). CB No. 12906. DP Barcode: D197037.
Document(PDF) (2995 KB PDF).
July 08, 1994. Memorandum. 25 Page(s).
Betsy Grim. Environmental Fate & Effects Branch.
Transmittal of EFED List A Summary Report for Metalaxyl. (Chemical 113501) Case# 0081.
Document(PDF) (3012 KB PDF).
July 18, 1994. Memorandum. 42 Page(s).
Flora Chow. Chemical Coordination Branch.
The HED Chapter of the Reregistration Eligibility Decision Document (RED)
for Metalaxyl, Case# 0081. Tox review 011142.
Document(PDF) (1354 KB PDF).
August 12, 1994. Memorandum. 1 Page(s).
G. F. Kramer. Chemistry Branch I.
Concurrence with comment on draft of Federal Register Notice on the tolerance
for metalaxyl leafy vegetables (excluding Brassica and spinach). CBTS# 14181.
Document(PDF) (34 KB PDF).
August 12, 1994. Memorandum. 45 Page(s).
G. F. Kramer. Chemistry Branch I, Tolerance Support.
Concurrence with comment on draft of Federal Register Notice on the tolerance
for metalaxyl leafy vegetables (excluding Brassica and spinach). CBTS# 14181.
Pages 7-10 deleted, CSF.
Document(PDF) (1282 KB PDF).
Attachment(s) Following:
June 21, 1991. Memorandum.
Shanaz Bacchus. Chemistry Branch I.
PP#OF3893 (EPA Reg. Nos. 100-607, 100-608): Metalaxyl Technical: (Ridomil®2E).
Tolerance In/On Leafy Vegetables (Excluding Brassica Vegetables, Excluding Spinach).
Analysis of Residue Data and Analytical Method.
MRID#s: 415878-00, -01, DP Barcode 156811.
December 18, 1991. Memorandum.
Robert Lascola. Chemistry Branch I-Tolerance Support.
PP#0F3893: Metalaxyl (Ridormil 2E, 5G) in/on Leafy Vegetables
(Excluding Brassica, Excluding Spinach). Amendment of 9/9/91. CBTS# 8898.
MRID# 420211-01. DP Barcode# D171050.
May 12, 1992. Memorandum.
Robert Lascola. Chemistry Branch I-Tolerance Support.
PP#0F3893. Metalaxyl (Ridormil 2E, 5G) in/on Leafy Vegetables (Excluding
Brassica, Excluding Spinach). Amendment of 3/17/92. CBTS# 9710. No MRID#.
DP Barcode# D176810.
*End of Attachments*
August 15, 1994. Memorandum. 4 Page(s).
Susan Hummel. Chemistry Branch.
Metalaxyl (113501) - Reregistration Case No. 0081. Ciba Geigy letter of July 21, 1994.
CB No. 14124, DP Barcode: D206106.
Document(PDF) (178 KB PDF).
October 03, 1994. Memorandum. 7 Page(s).
Krystyna Locke. Toxicology Branch.
Metalaxyl - Review of Additional Data to Upgrade the Core-Classification
of a Rat Metabolism Study. DP Barcode D206107. MRID 43317301 - to upgrade
MRID 41664501. Tox review 011289.
Document(PDF) (181 KB PDF).
October 17, 1994. Memorandum. 35 Page(s).
Susan V. Hummel. Chemistry Branch II.
Metalaxyl (113501) - Reregistration Case No. 0081.
Addendum to RED Residue Chemistry Chapter, Rotational Crop Studies
(GLN 165-1 and 165-2); Supporting Storage Stability Data.
MRID Nos. [42196501], 42196502, 42196503, 41870308, 43317302.
Document(PDF) (2008 KB PDF).
March 21, 1995. Memorandum. 80 Page(s).
Maria Isabel Rodriguez. Chemistry Branch I-Tolerance Support.
PP2F04105: Metalaxyl in or on Non-grass Animal Feeds (as Clover).
Amendment Dated February 7, 1994.
CBTS #15086; DP Barcode # D211743; No MRID #.
Document(PDF) (1983 KB PDF).
Attachment(s) Following:
August 17, 1993. Memorandum.
Maria Isabel Rodriguez. Chemistry Branch I-Tolerance Support.
ID # PP2F4105: metalaxyl (RidomiL 2E) in or on Non-grass Animal Feeds (as Clover).
Evaluation of Analytical and Residue Data. CBTS #9625. EPA Reg. #100607.
DP Barcode # D175974. MRID # 422268-01.
February 04, 1994. Letter.
Gregory R. Watson. Ciba-Geigy Corporation.
METALAXYL TECHNICAL (EPA REG. NO. 100-601) AND RIDOMIL® 2E
EPA REG. NO. 100-607); PP NO. 2F4105 NON-GRASS ANIMAL FEEDS
CROP GROUPING: SUBMISSION OF REVISED SECTION B AND F,
SUPPLEMENTAL LABELING.
*End of Attachments*
May 02, 1995. Memorandum. 9 Page(s).
Roger Gardner. Toxicology Branch.
Metalaxyl. Toxicology Chapter for the RED. Tox review 011142.
Document(PDF) (482 KB PDF).
May 16, 1995. Memorandum. 4 Page(s).
Maxie Jo Nelson. Chemistry Branch.
PP#2F04063. Metalaxyl (113501) in/on Grass Forage, Fodder, and Hay Crop Group (#17).
Letter of 6/13/94 Amending Petition. DP 208076; CBTS 14525; MRID 43271001.
Document(PDF) (93 KB PDF).
May 16, 1995. Memorandum. 4 Page(s).
Maxie Jo Nelson. Chemistry Branch.
PP#2F04072. Metalaxyl (113501) in/on the Brassica Leafy Vegetables Group (#5).
Letter of 5/2/94 Amending Petition. DP 208058; CBTS 14524; MRID 43218501.
Document(PDF) (89 KB PDF).
July 13, 1995. Memorandum. 11 Page(s).
Hank Appleton. Versar, Inc. for EPA/OPP.
Applicator Exposure/Worker Exposure While Treating Seed. MRID 43080049.
Document(PDF) (333 KB PDF).
December 01, 1995. . 4 Page(s).
Environmental Fate and Effects Division..
Ground Water Classification by Regulation. Metalaxyl.
Document(PDF) (795 KB PDF).
April 24, 1996. Memorandum. 23 Page(s).
Linda Kutney. Chemistry Branch-Tolerance Support.
Mefenoxam: Replacement of Metalaxyl Technical with Mefenoxam Technical;
Review of Bridging Data, D223261. CBTS No. 16909. PRIORITY 6.
MRID 438003-00,-01,-22 and -23. 438898-01,-02,-03,-21
438969-01,-02,-03,-04,-05. TOX 375AA. Pages 21-23 deleted, MP.
Document(PDF) (760 KB PDF).
June 04, 1996. Memorandum. 6 Page(s).
Linda Kutney. Chemistry Branch.
Mefenoxam: Replacement of Metalaxyl Technical with Mefenoxam Technical;
Review of Bridging Data on Oranges, D225972. CBTS No. 17192. MRID 439619-01.
ID #:000100-TOR PRAT CASE #: 039771.
Document(PDF) (191 KB PDF).
June 13, 1996. Memorandum. 89 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Review of Avian Reproduction Studies with Metalaxyl.
MRID 43624601 thru 43624603.
Document(PDF) (5559 KB PDF).
December 12, 1996. Memorandum. 13 Page(s).
Daniel Rieder. Ecological Effects Branch.
Review information to upgrade Avian Reproduction Studies.
MRID 441100-01, 43624601, 43624602.
Document(PDF) (764 KB PDF).
April 14, 1999. DER. 38 Page(s).
Max Feken. Golder Associates Inc. for EFED.
71-4 -- Avian Reproduction Test (Mallard) MRID 44761701.
Document(PDF) (2266 KB PDF).
November 03, 1999. Memorandum. 40 Page(s).
Brian Montague. Environmental Fate & Effects Division.
Review of Avian Reproduction Studies with Bobwhite quail (MRID 44755001) and
Mallard duck (MRID 44761701) exposed to Metalaxyl. Barcodes: D253399 and
D254022 [see cleared metalaxyl review of 4/14/99 re MRID 44761701).
Document(PDF) (2414 KB PDF).
April 03, 2000. Memorandum. 14 Page(s).
Robert Zendzian. Science Evaluation Branch.
CGA 329351 (Metalaxyl) Dermal absorption studies in vivo and in vitro.
DP Barcode# D264340. MRID # none. Tox review No. 014126.
Document(PDF) (374 KB PDF).
March 13, 2001. Memorandum. 31 Page(s).
Nancy Dodd. Registration Action Branch.
ID# 113501. Metalaxyl/Mefenoxam Storage Stability in Plants.
MRID Nos. 44316101 & 44850301.
Document(PDF) (1410 KB PDF).
March 13, 2001. Memorandum. 31 Page(s).
Nancy Dodd. Registration Action Branch HED.
Metalaxyl/Mefenoxam Storage Stability in Plants. MRIDs 44316101 and 44850301.
Document(PDF) (1452 KB PDF).
March 13, 2001. Memorandum. 32 Page(s).
Nancy Dodd. Registration Action Branch 3.
SUBJECT: ID#113501. Metalaxyl/Mefenoxam Storage Stability in Plants.
DP Barcode D257302. MRID No. 44316101 and 44850301.
Document(PDF) (909 KB PDF).
June 11, 2001. Memorandum. 21 Page(s).
Nancy Dodd. Registration Action Branch HED.
Metalaxyl/Mefenoxam Storage Stability in Livestock Commodities.
MRIDs 44316102 and 44617001.
Document(PDF) (935 KB PDF).
September 13, 2001. Memorandum. 14 Page(s).
Nancy Dodd. Registration Action Branch 3.
Metalaxy/Mefenoxam Analytical Method Recovery Data in Livestock Commodities.
DP Barcode D275477. MRID No. 44208101.
Document(PDF) (371 KB PDF).
September 13, 2001. Memorandum. 16 Page(s).
Nancy Dodd. Registration Action Branch 3.
Metalaxyl/Mefenoxam Analytical Method Recovery Data in Plants.
DP Barcode D276001. MRID No. 44208107.
Document(PDF) (406 KB PDF).
February 09, 2002. Memorandum. 39 Page(s).
Sayed Tadayon. Chemistry Exposure Branch HED.
Worker exposure to Apron® flowable while treating seed commercially.
DP Barcode No. D280679. EPA MRID No. 43080049.
Document(PDF) (2313 KB PDF).
Attachment(s) Following:
January 04, 2002. Review.
STUDY TYPE: Mixerloperator, Bagger, and Bag Sewer Passive Dosimetly Study
Using Whole Body Dosimetry and Personal Air Sampling. TEST MATERIAL:
Apron® is a systemic fungicide produced by Ciba-Geigy Corp….
*End of Attachments*
June 26, 2008. Review. 14 Pages.
Shyam Mathur. Technical Review Branch/RD.
FEE.PRODUCT CHEMISTRY REVIEW OF MP [] EP [X] DP BARCODE No.: D351187, 347125
File Symbol No.: 264-RNTE PRODUCT NAME: Proceed MD Fungicide. Decision No. 386008.
Product ingredient souce info. on p. 1, CSF info. on p. 9-14 deleted.
MRID No. 472770-01.
Document(PDF) (332 KB PDF).
August 05, 2008. Review. 4 Pages.
Shyam Mathur. Technical Review Branch/RD.
FEE.PRODUCT CHEMISTRY REVIEW OF MP [] EP [X] DP BARCODE No.: D355153
File Symbol No.: 264-RNTE (a) PRODUCT NAME: Proceed MD Fungicide...
FOOD USE [X] Decision No. 386008; inert ingredient & souce info. on p. 1,
inert on p. 3, CSF info. on p. 4 are deleted.
Document(PDF) (96 KB PDF).
December 22, 2010. DER. 39 Pages.
Thomas Steeger. Environmental Risk Branch IV.
HONEY BEE - FIELD TESTING FOR POLLINATORS. §141-5 (OPPTS 850. 3040).
DP Barcode: D336888. MRID No. 469078-01 (with 469078-02).
Document(PDF) (965 KB PDF).