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Index of Cleared Science Reviews Alachlor (PC Code 090501)
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Undated. Memorandum. 1 Page.
Jeanne Briskin. National Pesticide Survey.
Results of Monsanto survey of 5 pesticides in drinking water wells.
Document (PDF) (271 KB PDF).
Undated. Memorandum. 12 Page(s).
Padma Datta. Exposure Assessment Branch.
Review of Six Documents Regarding Monitoring of Pesticides in Northwestern
Ohio Rivers.
Document (PDF) (693 KB PDF).
Undated. Memorandum. 3 Page(s).
Stuart Cohen. Exposure Assessment Branch.
Des Moines, Iowa - Trip Report.
Document (PDF) (424 KB PDF).
Undated. Memorandum. 6 Page(s).
Mary Frankenberry. Environmental Fate & Effects Division.
Review of Alachlor Ground Water Survey Design.
Document (PDF) (424 KB PDF).
September 07, 1978. Memorandum. 9 Page(s).
Larry Anderson. Toxicology Branch.
Addition of Data to the Files for Caswell #295, 63, 740, 634, 11, 284A, 435.
Document (PDF) (418 KB PDF).
September 26, 1978. Memorandum. 21 Page(s).
Larry Anderson. Toxicology Branch.
Lasso Technical, Lasso EC, Lasso II and Lasso + Atrazine 15G Addition of Data to
Files Tox review 000049.
Document (PDF) (1202 KB PDF).
March 09, 1979. Memorandum. 13 Page(s).
Larry Anderson. Toxicology Branch.
Tolerances Requested for Residues of Lasso... in or on Sugarcane and Sugarcane
Forage and Fodder. PP 9F2144. Product impurity information on page 2 is not
included. Inert ingredient info on pages 12 and 13 not included. Tox review 000047.
Document (PDF) (1092 KB PDF).
May 30, 1979. Memorandum. 1 Page(s).
K. Zee. CBIB.
Analysis of Alachlor in the Presence of Metolachlor.
Document (PDF) (34 KB PDF).
September 07, 1979. Memorandum. 3 Page(s).
M. A. Gross. Toxicology Branch.
Validation Report on IBT Study No. 622-01185 - Three-Genera- tion Reproduction
Study on Lasso Technical in Albino Rats. Tox review 000050.
Document (PDF) (123 KB PDF).
October 22, 1979. Memorandum. 4 Page(s).
John Doherty. Toxicology Branch.
EPA File No. 876-25, Banvel and Tank Mixes with Various Other Herbicides.
Caswell Nos. 295, 315, 11, 434A, 188DD.
Document (PDF) (159 KB PDF).
February 23, 1981. Memorandum. 13 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 524-GUR. MON-8001. Caswell Nos. 11, 661A.
Document (PDF) (695 KB PDF).
March 24, 1981. Memorandum. 2 Page(s).
Roland Gessert. Toxicology Branch.
Teratology Study in Rats with Alachlor. Conducted by International Research &
Development Corporation for Monsanto Agricultural Products Company.
Tox review 000399. Tox review 001021 (duplicates).
Document (PDF) (193 KB PDF).
April 28, 1981. Memorandum. 2 Page(s).
Roland Gessert. Toxicology Branch.
Teratology Study in Rats with Alachlor. Conducted by International Research
& Development Corporation for Monsanto Agricultural Products Company.
Document (PDF) (94 KB PDF).
June 23, 1981. Memorandum. 11 Page(s).
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, -314, -285, -296, Lasso (Alachlor), Accession No. 244369.
Document (PDF) (626 KB PDF).
August 06, 1981. Review. 2 Page(s).
Elizabeth Zucker. Ecological Effects Branch.
Submission of Avian Acute Oral LD50 Study with Bobwhite Quail.
Document (PDF) (89 KB PDF).
January 07, 1982. Memorandum. 9 Page(s).
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Lasso (Alachlor), Three-Generation Rat Reproduction,
Caswell #11, Accession #070177.
Document (PDF) (513 KB PDF).
April 22, 1982. Review. 8 Page(s).
Willa Garner. Environmental Fate Branch.
Catfish Study.
Document (PDF) (247 KB PDF).
May 25, 1982. Review. 41 Page(s).
Willa Garner. Environmental Fate Branch.
Exposure Studies. Confidential business information deleted from pages 2,
3, 7-10, 15, 20, 21, 40, 41.
Document (PDF) (1491 KB PDF).
June 11, 1982. Memorandum. 2 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor Risk Assessment.
Document (PDF) (68 KB PDF).
June 16, 1982. Memorandum. 18 Page(s).
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor. Review of Monsanto 18-Month Oncogenic Study in
Mice... Acc. Nos. 070168 and 070169. Inert Ingredient Information on page 2
is not included. Tox review 001990.
Document (PDF) (1149 KB PDF).
June 16, 1982. Memorandum. 21 Page(s).
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor, Review of Monsanto Chronic Feeding/Oncogenicity
Study of Alachlor in Rats... Acc. Nos. 070586, -87, -88, -89 and -90.
Inert Ingredient information on page 2 is not included. Tox review 001991.
Document (PDF) (1439 KB PDF).
June 25, 1982. Memorandum. 19 Page(s).
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor. Review of Monsanto Six-Month Subchronic Feeding
Study in Dogs. Acc. Nos. 246292, 246293 and 247376. Tox review 002483.
Document (PDF) (1028 KB PDF).
July 20, 1982. Memorandum. 28 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), a Herbicide. EPA Reg. #524-316, -285, -296, and -314. Proposed
Tolerances... Confidential business information deleted from pages 4, 9-11, 14, 16, 17.
Document (PDF) (1950 KB PDF).
August 05, 1982. Memorandum. 2 Page(s).
Linda Propst. Residue Chemistry Branch.
EPA Reg. No. 524-316. Alachlor Residues on Various Raw Agricultural
Commodities.
Document (PDF) (81 KB PDF).
August 16, 1982. Memorandum. 8 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor Teratology Study in Rabbits... A Response to Monsanto's Comments
Concerning the 6/23/81 Review of this Study.
Document (PDF) (456 KB PDF).
August 17, 1982. Memorandum. 3 Page(s).
David Ritter. Toxicology Branch.
Proposal to Exempt an Inert Ingredient from the Requirement of a Tolerance. Pending
registration information on page 1 and manufacturing process information on page 3 are
not included.
Document (PDF) (130 KB PDF).
September 09, 1982. Memorandum. 12 Page(s).
John Onley. Residue Chemistry Branch.
PP #2F2681. Lasso ME on Various Crops. Evaluation of Analytical Methods and
Residue Data. Inert ingredient information on page 2 and manufacturing process
information on page 4 are not included.
Document (PDF) (867 KB PDF).
September 21, 1982. Memorandum. 2 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor; EPA Reg. #524-316. A Request to Terminate Lifetime Rat Feeding Study
at Two Years.
Document (PDF) (52 KB PDF).
September 21, 1982. Memorandum. 5 Page(s).
Amal Mahfouz. Toxicology Branch.
Lasso; Alachlor, EPA Reg. #524-316. Response to Monsanto's Letter of 8/13/82.
Document (PDF) (254 KB PDF).
November 12, 1982. DER. 18 Page(s).
J. MacPherson. Environmental Fate Branch.
Case GS 0063; Alachlor; Study 3; Metabolism - Aerobic Soil. MRID No. 00023014.
Document (PDF) (758 KB PDF).
November 23, 1982. Review. 6 Page(s).
E. Regelman. Environmental Fate Branch.
Response to Exposure Assessment.
Document (PDF) (195 KB PDF).
January 12, 1983. Memorandum. 9 Page(s).
John Onley. Residue Chemistry Branch.
PP #2F2681. Lasso ME (Encapsulating Alachlor) on Various Crops. Amendment of
10/27/82. Inert ingredient information on page 1 and pending registration information on
pages 5, 7, and 9 are not included.
Document (PDF) (633 KB PDF).
January 27, 1983. Report. 13 Page(s).
Environmental Fate and Effects Division.
Alachlor; Task 2: Environmental Fate & Exposure Assessment; Initial Draft Report.
Document (PDF) (865 KB PDF).
February 09, 1983. Memorandum. 4 Page(s).
John Onley. Residue Chemistry Branch.
PP #2F2681. Present Status on the Proposed Use of Lasso ME (Encapsulating
Alachlor) on Various Crops. Pending registration information on pages 3-4
is not included.
Document (PDF) (255 KB PDF).
March 01, 1983. Final Report. 12 Page(s).
Dynamac Corporation.
Alachlor - Task 2: Environmental Fate and Exposure Assessment.
Document (PDF) (533 KB PDF).
March 11, 1983. Data Eval. Rec.. 3 Page(s).
John Strange. Dynamac Corp. for Toxicology Branch.
3. Data Evaluation Record Mutagenicity Screening of Pesticides in the Microbial
System. Mutation Research 40:19-30 Accession 248053. MRID 000GS-05.
Document (PDF) (118 KB PDF).
March 11, 1983. Data Eval. Rec.. 4 Page(s).
John Strange. Dynamac Corp. for Toxicology Branch.
4. Data Evaluation Record The Ames Mutagen Assay Tested Against Herbicides and
Herbicide Combinations. Soil Science 131(1):44-47. Accession 248053.
Document (PDF) (152 KB PDF).
March 23, 1983. Memorandum. 6 Page(s).
Orville Paynter. Toxicology Branch.
Alachlor; EPA Reg. #524-316. Additional Information on Chronic Rat, Chronic
Mouse, and Monkey Absorption Studies. Accession Nos.: 247922 and 247937;
CASWELL # 11.
Document (PDF) (352 KB PDF).
March 24, 1983. Data Eval. Rec. 4 Page(s).
Curtis Laird. Ecological Effects Branch.
Alachlor. Final Report: Acute Oral LD50 - Bobwhite Quail.
Document (PDF) (140 KB PDF).
May 02, 1983. Memorandum. 2 Page(s).
John Onley. Residue Chemistry Branch.
PP #2F2681. Lasso ME (Encapsulating Alachlor) on Various Crops. Amendment of
February 1, 1983. Pending registration information on page 1 is not included.
Document (PDF) (91 KB PDF).
June 23, 1983. Memorandum. 30 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor (Technical); EPA Reg. # 524-316 and Lasso EC (45% a.i.) EPA Reg.
#524-314. Review of Acute Inhalation and Mutagenicity Studies... Confidential
business information on page 5 not included. Acc. 248053, MRID 000GS-05.
Document (PDF) (1279 KB PDF).
June 27, 1983. Memorandum. 16 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. #524-316. Review of a 21-Day Dermal Toxicity with Rabbits.
Document (PDF) (730 KB PDF).
February 29, 1984. Memorandum. 23 Page(s).
Amal Mahfouz. Toxicology Branch.
Lasso (Alachlor), EPA Reg. # 524-316; Review of the Rat Metabolism Study;
Accession Nos. 251543, 251544.
Document (PDF) (1087 KB PDF).
March 13, 1984. Memorandum. 2 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor, Reg. No. 524-316. Upgrading the Classification of Two Acute Inhalation
Studies. Tox Review No. 003671.
Document (PDF) (67 KB PDF).
April 04, 1984. Review. 69 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Alachlor Exposure Assessment. Confidential business information is deleted from
pages 48-54, and 58.
Document (PDF) (2475 KB PDF).
April 10, 1984. Memorandum. 3 Page(s).
Nancy Dodd. Residue Chemistry Branch.
EPA Registration # 524-316, Alachlor.
Document (PDF) (169 KB PDF).
April 13, 1984. Memorandum. 6 Page(s).
Padma Datta. Exposure Assessment Branch.
Review of Hydrogeology, Water Quality & Land Management in the Big Spring
Basin, Clayton County, Iowa.
Document (PDF) (333 KB PDF).
April 17, 1984. Memorandum. 28 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. # 524-316. Review of a New Chronic Feeding/Oncogenicity
Study in Rats by Monsanto. Accession Nos. 252496, 252497, 252498. Confidential
business information is deleted from pages 3, 4, and 21. Tox review 003753.
Document (PDF) (3203 KB PDF).
April 20, 1984. Memorandum. 1 Page(s).
Amal Mahfouz. Toxicology Branch.
Clarification Concerning the Identification of the Ongoing New Chronic Feeding
Study in Rats.
Document (PDF) (54 KB PDF).
April 20, 1984. Memorandum. 1 Page(s).
Amal Mahfouz. Toxicology Branch.
Review of Summary Letter by Monsanto.
Document (PDF) (71 KB PDF).
April 25, 1984. Memorandum. 4 Page(s).
Bertram Litt. Toxicology Branch.
Alachlor, EPA Reg. No. 524-316. Quantitative Risk Assessment Based on
Feeding/Oncogenicity Study in Rats, Accession Nos. 252496, 252497, 252498.
Document (PDF) (217 KB PDF).
June 29, 1984. Memorandum. 5 Page(s).
Nancy Dodd. Residue Chemistry Branch.
EPA Registration No. 524-316. Feeding of Radiolabeled Alachlor Metabolites to
Laying Hens. Accession No. 252792.
Document (PDF) (233 KB PDF).
July 03, 1984. Memorandum. 5 Page(s).
Nancy Dodd. Residue Chemistry Branch.
EPA Registration No. 524-316. Feeding of Radiolabeled Alachlor Metabolites to
Lactating Goats. Accession No. 252793.
Document (PDF) (254 KB PDF).
August 14, 1984. Memorandum. 2 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 524-316 Alachlor. Submitted Dermal Sensitization Study.
Accession No. 252772.
Document (PDF) (71 KB PDF).
August 29, 1984. Memorandum. 16 Page(s).
Stephen Dapson. Toxicology Branch.
Review of Teratology Study in Rabbits with Alachlor Registration No. 524-316,
Accession No. 252570.
Document (PDF) (777 KB PDF).
October 12, 1984. Memorandum. 8 Page(s).
Irving Mauer. Toxicology Branch.
Alachlor RPAR: Mutagenicity Studies, EPA Reg Nos. 524-285, 524-296, 524-314,
524-316.
Document (PDF) (453 KB PDF).
November 02, 1984. Memorandum. 37 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Review of Additional Studies: A Special
Chronic Study in Rats and Two New Mutagenicity Studies. Confidential business
information is deleted from pages 4, and 30.
Document (PDF) (1828 KB PDF).
November 13, 1984. Memorandum. 4 Page(s).
William Burnam. Health Effects Division.
Alachlor (Lasso), EPA Reg. #524-316, EPL's Re-Evaluation of Nasal Cavity
Lesions in a 2-year chronic study in rats # ML-80-186 (8002184), by Monsanto.
Tox review 004091.
Document (PDF) (187 KB PDF).
November 19, 1984. Memorandum. 4 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316, EPL's Re-Evaluation of Nasal Cavity
Lesions in a 2-Year Chronic Study in Rats.
Document (PDF) (188 KB PDF).
November 30, 1984. Memorandum. 15 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Protocol - Percutaneous Absorption
in Monkeys.
Document (PDF) (660 KB PDF).
December 19, 1984. Review. 1 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Alachlor Exposure Assessment Study - Protocol Review.
Document (PDF) (134 KB PDF).
Attachment(s) Following:
December 18, 1984. Memorandum. 2 Page(s).
Curt Lunchick. Exposure Assessment Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Protocol - Lasso Herbicide
Application Exposure Study Biological Monitoring 1984 Field and Sample Protocol.
*End of Attachments*
February 07, 1985. Memorandum. 5 Page(s).
Michele Loftus. Residue Chemistry Branch.
Special Review of Alachlor. Analytical Methodology for Milk and Meat Tissues.
Accession No. 255600.
Document (PDF) (319 KB PDF).
February 26, 1985. Memorandum. 1 Page(s).
David Severn. Exposure Assessment Branch.
Monsanto's Monitoring Protocol for Alachlor.
Document (PDF) (150 KB PDF).
Attachment(s) Following:
Undated. Letter. 2 Page(s).
David Severn. Exposure Assessment Branch.
Re: Public Water Supplies.
*End of Attachments*
March 01, 1985. Memorandum. 7 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of STORET data of alachlor in surface water.
Document (PDF) (293 KB PDF).
July 16, 1985. Memorandum. 2 Page(s).
Susan Hummel. Chemistry & Exposure Branch.
Alachlor Response to Registration Standard. EPA Reg. Nos. 524-285, 524-296, 524-
314, 524-329, 524-341, 524-344 (Accession No. 257288; RCB Nos. 1014, 1015,
1016, 1017). Quality control procedure information on page 2 is not included.
Document (PDF) (122 KB PDF).
July 18, 1985. Final Report. 7 Page(s).
Dynamac Corporation.
Alachlor Addendum - Task 2: Environmental Fate and Exposure Assessment.
Document (PDF) (294 KB PDF).
July 30, 1985. Review. 7 Page(s).
Amal Mahfouz. Toxicology Branch.
STUDY/ACTION TYPE: Metabolism: Identification of Metabolites in [Monkey] Urine.
Pages 7-13 removed, registrant data. MRID 152211. Accession 257283 and 258993.
Tox review 004723.
Document (PDF) (303 KB PDF).
September 19, 1985. Memorandum. 46 Page(s).
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. No. 524-316. Evaluation of Newly Submitted Studies: A One
Year Feeding Study in Dogs, Accession # 255953; and a CHO/HGPRT Mammalian
Cell Forward Mutation Study, Accessions # 255952. TXR 004660. Pp. 19-25, 36-45
removed, registrant data.
Document (PDF) (1662 KB PDF).
September 20, 1985. Memorandum. 4 Page(s).
Stuart Cohen. Exposure Assessment Branch.
Company response to EPA letter on ground-water monitoring.
Document (PDF) (159 KB PDF).
September 25, 1985. Memorandum. 2 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Meeting with Monsanto on Surface & Ground Water Monitoring Protocols for Alachlor.
Document (PDF) (72 KB PDF).
October 03, 1985. Memorandum. 4 Page(s).
Stuart Cohen. Exposure Assessment Branch.
Ground Water Monitoring Protocol.
Document (PDF) (169 KB PDF).
October 25, 1985. Memorandum. 1 Page(s).
Michele Loftus. Residue Chemistry Branch.
Alachlor Special Review. Request for Information from BUD.
Document (PDF) (53 KB PDF).
December 04, 1985. Memorandum. 5 Page(s).
Joseph Reinert. Exposure Assessment Branch.
PD 1, rebuttal.
Document (PDF) (356 KB PDF).
December 06, 1985. Memorandum. 5 Page(s).
Paul Lapsley. Special Review Branch.
Technical guidance for Alachlor Water Monitoring Studies.
Document (PDF) (272 KB PDF).
January 23, 1986. Memorandum. 14 Page(s).
Michele Loftus. Residue Chemistry Branch.
524-316. Alachlor Special Review. Response to the Alachlor Registration Standard.
Cattle Feeding Study, Poultry Feeding Study, and Swine Feeding Study.
Acc. Nos. 256625, 257273, and 257272.
Document (PDF) (696 KB PDF).
January 23, 1986. Memorandum. 4 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of rebuttal comments from Monsanto in support of No-Till practices
& the use of alachlor.
Document (PDF) (222 KB PDF).
January 29, 1986. Memorandum. 4 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Reg./File No.: 644(30000/44), 565(30000/44). Comments on alachlor PD #1.
Document (PDF) (177 KB PDF).
January 29, 1986. Memorandum. 5 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Reg./File No.: 391(30000/44). Comments on alachlor PD #1.
Document (PDF) (330 KB PDF).
March 20, 1986. Memorandum. 7 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of Surface Water.
Document (PDF) (375 KB PDF).
March 20, 1986. Memorandum. 7 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of Surface Water.
Document (PDF) (412 KB PDF).
March 20, 1986. Memorandum. 7 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of Surface Water.
Document (PDF) (386 KB PDF).
March 28, 1986. Memorandum. 6 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of Surface Water.
Document (PDF) (284 KB PDF).
March 29, 1986. Memorandum. 5 Page(s).
Theodore Farber. Toxicology Branch.
Addenda to Two Chronic Feeding Studies in Rats and Mice with Alachlor.
Accession No. 256735. Tox review 005005.
Document (PDF) (232 KB PDF).
May 23, 1986. Memorandum. 6 Page(s).
Michele Loftus. Residue Chemistry Branch.
524-316 - Alachlor Special Review and Response to the Alachlor Registration
Standard. Analytical Methodology for Meat, Milk, and Eggs.
Document (PDF) (282 KB PDF).
June 26, 1986. Memorandum. 17 Page(s).
Esther Rinde. Toxicology Branch.
Peer Review of Alachlor. Inert ingredient information on pages 4, 5, 9 is not included.
Document (PDF) (925 KB PDF).
August 14, 1986. Memorandum. 1 Page(s).
Susan Hummel. Residue Chemistry Branch.
090501 - Alachlor - PD 2/3 Concurrence.
Document (PDF) (47 KB PDF).
September 02, 1986. Letter. 5 Page(s).
Richard Kelley. Hazard Evaluation Division.
Enclosing data from Iowa on Alachlor.
Document (PDF) (120 KB PDF).
December 24, 1986. Memorandum. 8 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Processing/Cooking Studies
(Accession No. 264946; RCB No. 1443).
Document (PDF) (493 KB PDF).
January 09, 1987. Memorandum. 10 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Ground Water Contamination of Alachlor in NY state. Personal Privacy information
removed from pages 5-10.
Document (PDF) (249 KB PDF).
January 09, 1987. Memorandum. 3 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Ground Watetr Monitoring Protocol.
Document (PDF) (86 KB PDF).
January 30, 1987. Memorandum. 58 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard Residue Data on Corn, Milo,
Peanuts, and Corn Processing Study. Monsanto Report Numbers...
(Accession Nos. 262999, 263002, 263022, 264946; RCB Nos. 1367, 1368, 1369, 1444).
Document (PDF) (3200 KB PDF).
February 17, 1987. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Special Review and Monsanto Response to
Registration Standard.
Document (PDF) (170 KB PDF).
February 27, 1987. Memorandum. 6 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 524-EUP-AI. Partner WDG. Pages 5-6 removed, draft label.
Tox review 006241.
Document (PDF) (206 KB PDF).
March 20, 1987. Memorandum. 10 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of amendments to well water protocol.
Document (PDF) (496 KB PDF).
April 17, 1987. Memorandum. 7 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of ground water monitoring study. Registration Data information
removed from pages 5-7.
Document (PDF) (228 KB PDF).
June 02, 1987. Memorandum. 26 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor Response to Registration Standard Method Trial Request for 2 Alachlor
Metabolites on Peanuts and Peanut Hay. Page 25 is not included -
commercial/financial information.
Document (PDF) (1108 KB PDF).
June 12, 1987. Memorandum. 2 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Request for Updated Market Share Data
(No MRID Number; No RCB Number).
Document (PDF) (65 KB PDF).
June 12, 1987. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Answers to Questions from 4/10/87 Meeting between David
Giamporcaro (SRB) and Monsanto Representatives
(No MRID Number; RCB No. 2287).
Document (PDF) (151 KB PDF).
June 12, 1987. Memorandum. 4 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of Monsanto's May 9, 1985, letter in reply to EPA's questions on alachlor
surface water monitoring program.
Document (PDF) (161 KB PDF).
June 15, 1987. Memorandum. 38 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Response to Registration Standard. EPA Reg. 524-316. Residue
Data on Dry Beans, Succulent Beans, Cottonseed, Sunflower Seeds, and Peanut
Processing...(MRID Nos. 400399-01, 400403-01, 400401-01, 400404-01;
RCB Nos. 1828 through 1833).
Document (PDF) (2399 KB PDF).
June 26, 1987. Memorandum. 312 Page(s).
Judith Hauswirth. Toxicology Branch.
Peer Review of Alachlor - Reconsideration of Classification Tox review 007699. Inert
ingredient information on pages 11, 12, 16, 31, 32, 36, 63, 64, 68, 108, 119, 189, 121,
124, 138,160,161,178,189,215,228 is not included. (deletion notes continued below).
Document (PDF) (12614 KB PDF).
Attachment(s) Following:
June 23, 1987. Memorandum. 312 Page(s).
Judith Hauswirth. Toxicology Branch.
Pending registration action info. on pages 20,21,22,40,41,42
72,73,74,117,118,128 is not included. Registrant data on pages 25-26,45-46,
77-78,129-136,183,200-202,209,218-219,221- 222,263-267,287-304 is not included.
Commercial/financial information on pages 184-185 is not included.
*End of Attachments*
June 26, 1987. Memorandum. 5 Page(s).
Judith Hauswirth. Toxicology Branch.
Peer Review of Alachlor - Reconsideration of Classification.
Document (PDF) (316 KB PDF).
July 02, 1987. Memorandum. 11 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of Monsanto Responses to June 18, 1986 Data Call-In (DCI) Notice for Use
& Exposure Data for Alachlor, Machine- Readable Data for Surface Water Protocol
& Analytical Methods. Commercial/Financial information removed from pages 8-11.
Document (PDF) (394 KB PDF).
July 02, 1987. Memorandum. 3 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of 1985 Alachlor Monitoring Protocol (Surface Water).
Document (PDF) (144 KB PDF).
July 02, 1987. Memorandum. 5 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of 1985 Alachlor Monitoring Data (Surface Water).
Document (PDF) (234 KB PDF).
July 02, 1987. Memorandum. 9 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of Rebuttal Comments for Technical Support Documents Surface Water
& Ground Water.
Document (PDF) (522 KB PDF).
July 02, 1987. Review. 19 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
EAB Review of Alachlor & Alternatives: Atrazine, Cyanazine, Linuron, Metribuzin,
Metolachlor, Simazine, Trifluralin, Butylate (Ground Water Monitoring Only). Review
of 1985 Surface and Ground Water Screening Results for Selected Herbicides for PD4.
Document (PDF) (1065 KB PDF).
July 20, 1987. Memorandum. 29 Page(s).
Judith Hauswirth. Toxicology Branch.
Alachlor Metabolism Study in Monkeys submitted by Monsanto Company November
10, 1986 Accession Number 400009-01 Pages 18-29 removed, registrant data.
Tox review 006013.
Document (PDF) (869 KB PDF).
August 18, 1987. Memorandum. 23 Page(s).
Stephen Saunders. Residue Chemistry Branch.
Dietary Exposure Analysis for Alachlor.
Document (PDF) (1599 KB PDF).
August 18, 1987. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor Residue Estimates for Use in the Tolerance Assessment System.
Document (PDF) (119 KB PDF).
August 20, 1987. Memorandum. 8 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Response to EPA Letter of 3/27/87, Regarding Special Review
Data Call-In Notice of June 9, 1986. Validation Data for Previously Submitted
Residue Data on Dry Beans...
(MRID No. 401897-01; RCB Nos. 2518, 2519, 2590, and 2591).
Document (PDF) (450 KB PDF).
August 21, 1987. Memorandum. 3 Pages.
Linda Kutney/Mary Hood. Exposure Assessment Branch.
Population of Community Water Systems with High Alachlor Concentrations.
Accession #402659-01. Pages 2-3 removed, registrant data.
Document (PDF) (279 KB PDF).
August 21, 1987. Memorandum. 5 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of Comments Received on July 20, 1987 Concerning the Office of Drinking
Water's 3/31/87 Health Advisory for Alachlor.
Document (PDF) (283 KB PDF).
August 25, 1987. Memorandum. 4 Page(s).
Matthew Lorber. Exposure Assessment Branch.
Review of well monitoring survey protocol amendments.
Document (PDF) (188 KB PDF).
August 25, 1987. Memorandum. 6 Page(s).
Matthew Lorber. Exposure Assessment Branch.
Review of well monitoring survey protocol amendments.
Document (PDF) (287 KB PDF).
September 03, 1987. Memorandum. 2 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - RCB Concerns Regarding OPPE Recommendation to Cancel
Alachlor Uses on Dry Beans (No MRID Number; No RCB Number).
Document (PDF) (105 KB PDF).
October 06, 1987. Review. 17 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
EAB Review of Alachlor. Submission of Final 1986 Surface Water Monitoring
Results for Alachlor, Atrazine, Cyanazine, Metolachlor, and Simazine.
Page 17 is not included - registration data.
Document (PDF) (841 KB PDF).
November 03, 1987. Memorandum. 68 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard Deficiencies.
EPA Reg. No. 524-316. Monsanto Letter of 5/29/87. Residue Data on Cottonseed,
Sunflower Seeds, Sorghum,...(MRID #s 402409-01, 402718-01, -02, 402753-01;
RCB #s 2597, 2596, 2609-2611).
Document (PDF) (4170 KB PDF).
November 09, 1987. Memorandum. 2 Page(s).
OPP. EPA.
Memorandum on Alachlor Q*.
Document (PDF) (56 KB PDF).
December 10, 1987. Memorandum. 12 Page(s).
Susan Hummel. Chemistry & Exposure Branch.
Alachlor (090501). Response to Registration Standard Deficiencies. Response to
Special Review DCI of 6/9/86. EPA Reg. No. 524-316. Monsanto Report Numbers:
MSL-6799 [MRID 403146-01]... MSL-6750 [MRID No. 403303-01]... MSL-6832
[MRID No. 403412-01].
Document (PDF) (703 KB PDF).
April 01, 1988. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Evaluation of Alachlor Method Validation. Two Alachlor Metabolites in Peanuts and
Peanut Hay.
Document (PDF) (299 KB PDF).
April 03, 1988. Note. 2 Page(s).
Charles Trichilo. Residue Chemistry Branch.
Note to Anne Barton re: 409 Tolerances for Alachlor.
Document (PDF) (75 KB PDF).
June 14, 1988. Memorandum. 2 Page(s).
Edward Zager. Residue Chemistry Branch.
Canadian Maximum Residue Limits for Alachlor.
Document (PDF) (70 KB PDF).
July 19, 1988. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard Deficiencies. Request for
Registration of Lasso Micro-Tech on Corn. EPA Reg. Nos. 524-316, 524-344.
Monsanto Letter of 2/19/88. Monsanto Submission of 12/11/87...
(No MRID No.; RCB Nos. 3461, 3462).
Document (PDF) (241 KB PDF).
July 21, 1988. Memorandum. 5 Page(s).
Susan Hummel. Residue Chemistry Branch.
Monsanto Submission of Proposed Regulatory Enforcement Method in Response to
Alachlor Registration Standard Method Validation Request for 2 Alachlor Metabolites
on Corn Grain and Fodder, Peanuts and Peanut Hay
(MRID No. 405580-01; No RCB Number).
Document (PDF) (229 KB PDF).
August 08, 1988. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Monsanto Submission of Proposed Regulatory Enforcement Method in Response to
Alachlor Registration Standard (MRID No. 405580-01; RCB No. 4112).
Document (PDF) (191 KB PDF).
September 30, 1988. Memorandum. 32 Page(s).
Stephen Dapson. Toxicology Branch.
Review of a Teratology Study in Rabbits with Alachlor. EPA MRID# 405794-01 and
405794-02, HED Project No. 8-1024, Caswell# 11. Tox review 006886.
Page 14-32 deleted-registrant data.
Document (PDF) (825 KB PDF).
December 01, 1988. Memorandum. 9 Page(s).
W. T. Chin. Dietary Exposure Branch.
PP #8F3671: Alachlor (Lasso) in or on Sorghum Forage. Evaluation of Analytical
Methods and Residue Data. (No Acc. or MRID Numbers, Record #229364; DEB #4299).
Quality control procedure information on page 3 is not included.
Document (PDF) (515 KB PDF).
June 12, 1989. Memorandum. 2 Page(s).
W. T. Chin. Dietary Exposure Branch.
PP #9F3738: Request for an Exemption from the Requirement of a Tolerance for the
Encapsulating Polymer in Lasso Micro-Tech Herbicide. (No MRID Number, DEB #5253).
Document (PDF) (96 KB PDF).
June 19, 1989. Memorandum. 4 Page(s).
W. T. Chin. Dietary Exposure Branch.
PP #8F3671/#9H5576: Alachlor in/on Sorghum Forage. Amendment of 2/10/89.
(PP #9H5576 and MRID #40511201) (DEB #5251 and #5252).
Document (PDF) (264 KB PDF).
March 04, 1992. Memorandum. 7 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review 6(a)(2) ground water monitoring data.
Document (PDF) (793 KB PDF).
March 04, 1992. Review. 7 Pages.
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Product Name: Lasso. Company Name: Monsanto Agricultural Company. Purpose:
Review 6(a)2 ground monitoring data. DP Barcode: D174028. MRID No. 41400001.
Document (PDF) (871 KB PDF).
January 12, 1993. Review. 7 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review 6(a)(2) Adverse Data Submission.
Document (PDF) (646 KB PDF).
February 19, 1993. Memorandum. 5 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Special Review Data (870); Product Specific Data (Reregistration-655);
(Generic Data Reregistration-660).
Document (PDF) (648 KB PDF).
April 28, 1993. Memorandum. 10 Page(s).
Stephen Dapson. Toxicology Branch.
ALACHLOR: Review of 6(a) (2) data - acute oral toxicity with MON5775 (81-1).
EPA MRID No.: 427015-00 and -01. Pages 8-10 removed, registration data.
Tox review 010195.
Document (PDF) (352 KB PDF).
May 18, 1993. Memorandum. 17 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review/Respond to 6(a)(2) action - Suffolk Co., New York.
Pages 10-11 removed, personal privacy.
Document (PDF) (794 KB PDF).
June 01, 1993. Memorandum. 32 Page(s).
Christine Olinger. Chemistry Branch.
Reregistration of Alachlor: Animal Metabolism Data; Chemical No. 90501; Branch
No. 11162; DP Barcode No. D186613; MRID Nos: 42594901 through 42594904.
Document (PDF) (1486 KB PDF).
September 01, 1993. Review. 5 Page(s).
Toxicology Branch.
Reference Dose for Chronic Oral Exposure (RfD) for alachlor.
Document (PDF) (424 KB PDF).
January 31, 1994. Memorandum. 6 Page(s).
George Ghali. Health Effects Division.
RfD/Peer Review Report of Alachlor.
Document (PDF) (329 KB PDF).
March 21, 1994. Memorandum. 3 Page(s).
Marcia Van Gemert. Toxicology Branch.
Toxicology Endpoint Selection Document for Alachlor.
Document (PDF) (148 KB PDF).
May 31, 1994. DER. 31 Page(s).
Jose Melendez. Environmental Fate & Ground Water Branch.
Alachlor Study 2; 00 Active Ingredient & 09 Microencapsulated (MCap).
MRID No. 00101531. Pages 12-31 removed, registrant data.
Document (PDF) (858 KB PDF).
May 31, 1994. DER. 8 Page(s).
Jose Melendez. Environmental Fate & Ground Water Branch.
Alachlor; Emlsifiable Concentrate (EC); Section 164. MRID Nos. 42528001,
-02, -03 & -04.
Document (PDF) (724 KB PDF).
July 21, 1994. Memorandum. 50 Page(s).
Stephen Dapson. Toxicology Branch.
MON 5775 (metabolite of ALACHLOR): Review of 91 day drinking water study in
rats. EPA MRID No: 428637-00 and -01. Pages 24-50 removed, registration data.
Tox review 011136.
Document (PDF) (1427 KB PDF).
August 01, 1994. Memorandum. 26 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
EEB's chapters for the Alachlor (SN 090501) RED. "We have revised our chapters
for the Reregistration Eligibility Document for Alachlor to incorporate your
suggestions.".
Document (PDF) (1199 KB PDF).
Attachment(s) Following:
June 10, 1994. Memorandum.
Anthony Maciorowski. Ecological Effects Branch.
Alachlor (SN 090501) avian dietary studies. 71-2(a) Bobwhite Quail Dietary
Toxicity, MRID 43087101. 71-2(b) Mallard Dietary Toxicity, MRID 43087001.
*End of Attachments*
January 17, 1995. Memorandum. 9 Page(s).
Stephen Dapson. Toxicology Branch.
MON 5775 (metabolite of ALACHLOR): Review of additional data for 91 day drinking
water study in rats, comments of State of Wisconsin letter and comments on minutes
of meeting with registrant. MRID No: none Tox review 011389.
Document (PDF) (698 KB PDF).
September 11, 1995. Memorandum. 6 Page(s).
Elizabeth Behl. Environmental Fate & Ground Water Branch.
Review of ground water monitoring data in rural Tennessee wells.
MRID No. 436088-01.
Document (PDF) (440 KB PDF).
March 07, 1996. Memorandum. 2 Page(s).
Kerry Dearfield. Office of Science Policy.
Comments on Third Carcinogenicity Peer Review of Alachlor.
Document (PDF) (162 KB PDF).
March 08, 1996. DER. 19 Page(s).
Brian Montague. Ecological Effects Branch.
Freshwater Fish Early Life-Stage Test. [Rainbow trout.] Guideline 72-4(a).
Page 19 removed, registrant data. MRID 43862601.
Document (PDF) (709 KB PDF).
March 14, 1996. Memorandum. 72 Page(s).
Stephen Dapson. Toxicology Branch II.
Carcinogenicity Peer Review of Alachlor - Third. Inert ingredient info pages 9, 11, and
42 is not included. Pending registration information on pages 21, 22, 23, 26 and 59 is
not included.
Document (PDF) (5046 KB PDF).
March 21, 1996. Data Eval. Rec.. 4 Page(s).
Brian Montague. Ecological Effects Branch.
Chemical: Alachlor sulfonic acid Acute Toxicity of Mon 5775 to Rainbow Trout
MRID No.: 43774704.
Document (PDF) (346 KB PDF).
March 21, 1996. Data Eval. Rec.. 4 Page(s).
Brian Montague. Ecological Effects Branch.
Chemical: MON 5775 Acute Toxicity of MON 5775 to Daphnia magna
MRID No.: 437747-03.
Document (PDF) (342 KB PDF).
March 21, 1996. DER. 22 Page(s).
Brian Montague. Ecological Effects Branch.
Aquatic Invertebrate Life Cycle Test. [Daphnia.] Guideline 72-4(b). MRID 43774707.
Document (PDF) (849 KB PDF).
April 03, 1996. Memorandum. 79 Page(s).
Stephen Dapson. Toxicology Branch II.
MON 5775 (ESA metabolite of Alachlor): Review of rat teratology study, mutagenicity
study and metabolism studies (special metabolism and cell proliferation) with MON
5775 and a comparison of the ESA metabolite... Pp. 75-79 removed, registrant data.
Document (PDF) (4391 KB PDF).
Attachment(s) Following:
April 03, 1996. Memorandum.
Stephen Dapson. Toxicology Branch II.
Pages 51-52, 75-79 removed, registrant data. MRIDs 43889401, -02, -04, 43908101.
Tox review 011861.
*End of Attachments*
May 24, 1996. Memorandum. 6 Page(s).
David Jones. Environmental Fate & Ground Water Branch.
Alachlor exposure assessment from acetochlor surface water monitoring study.
Document (PDF) (366 KB PDF).
July 01, 1996. Memorandum. 240 Page(s).
Jose Melendez. Environmental Fate & Ground Water Branch.
Alachlor Revised RED, EFGWB Science Chapter. Pages 142-240 removed,
registration data.
Document (PDF) (12723 KB PDF).
June 27, 1997. Memorandum. 14 Page(s).
Stephen Dapson. Toxicology Branch.
Carcinogenicity Peer Review of Alachlor (4th).
Document (PDF) (12723 KB PDF).
November 20, 1997. DER. 20 Page(s).
Jose Melendez. Environmental Risk Branch.
Alachlor; Terrestrial Field Dissipation; 164-1. Registration Data information removed
from pages 10-20. MRID No. 437747-01.
Document (PDF) (784 KB PDF).
March 04, 1998. DER. 25 Page(s).
Jose Melendez. Environmental Risk Branch.
Mobility-Adsorption/Desorption; Study 1. Registration Data information removed from
pages 5-25. MRID No. 444053-01.
Document (PDF) (247 KB PDF).
May 18, 1998. Memorandum. 116 Page(s).
Kathryn Boyle. Reregistration Branch 1.
Alachlor, The Partially Revised HED Chapter of the Reregistration Eligibility
Decision Document (RED), Case 0063, Chemical 090501. This document supersedes
the previous HED chapters signed March 5, 1995 and August 15, 1997.
Document (PDF) (4766 KB PDF).
May 28, 1998. Memorandum. 77 Page(s).
Sid Abel. Environmental Risk Branch.
EFED Revised RED Chapter for Alachlor (PC Code No. 090501).
Document (PDF) (6056 KB PDF).
February 11, 2000. DER. 27 Page(s).
Max Feken. Golder Associates Inc. for EEB.
71-4 -- Avian Reproduction Test. [Northern Bobwhite.] MRID 44951502.
Document (PDF) (1471 KB PDF).
February 11, 2000. DER. 28 Page(s).
Max Feken. Golder Associates Inc. for EEB.
71-4 -- Avian Reproduction Test. [Mallard.] MRID 44951501.
Document (PDF) (1568 KB PDF).