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Index of Cleared Science Reviews for Cypermethrin (Pc Code 109702)

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Undated. DER. 8 Page(s).
Miachel Rexrode. Ecological Effects Branch.
70-1-Special Test: Acute Toxicity Test with a Freshwater Invertebrates
(Chiromus riparius and Hyalella azteca) MRID 440744-01.
Document (PDF) (639 KB PDF).

October 22, 1976. Review. 4 Page(s).
R. W. Felthousen. Efficacy & Ecological Effects Branch.
Submission of data requirements.
Document (PDF) (154 KB PDF).

April 03, 1980. Review. 4 Page(s).
Carol Matti Natella. Ecological Effects Branch.
The acute oral toxicity (LD50) of PP383 to the mallard duck.
Document (PDF) (98 KB PDF).

April 09, 1980. Review. 5 Page(s).
Carol Natella. Ecological Effects Branch.
Fish acute 96-hour LC50 (Rainbow Trout) Acc. 241598.
Document (PDF) (209 KB PDF).

April 11, 1980. Review. 5 Page(s).
Carol Natella. Ecological Effects Branch.
Fish acute 96-hour LC50 (Bluegill) Acc. 241598.
Document (PDF) (200 KB PDF).

May 08, 1980. Review. 3 Page(s).
John Harris. Environmental Fate Branch.
Reg. No. 10182-EUP-19. Cymbush Insecticide. Experimental Use of New Chemical on Cotton.
However, the PM Requests a Total Assessment under Section 3 (c) (5).
Document (PDF) (108 KB PDF).

February 24, 1981. Review. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
Continuous flow 96-hr LC50; Bluegill Sunfish.
Document (PDF) (196 KB PDF).

February 26, 1981. Review. 5 Page(s).
Clayton Bushong. Ecological Effects Branch.
Proposed extension and expansion of EUP on cotton.
Document (PDF) (247 KB PDF).

April 14, 1981. Data Eval. Rec. 1 Page(s).
Thomas Johnston. Ecological Effects Branch.
48-hr EC50 and LC50; Pacific oyster larvae Acc. 070562.
Document (PDF) (45 KB PDF).

May 04, 1981. Review. 42 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 10182-EUP-19. Cymbush. Request for Extension of EUP.
Document (PDF) (2345 KB PDF).

May 21, 1981. Memorandum. 17 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 279-EUP-IA. Multicrop Use of FMC 45806 2.5 EC (Ammo)
Insecticide Containing Cypermethrin. Revised Submission.
Pages 8-17 removed, draft label Tox Review 004824.
Document (PDF) (770 KB PDF).

October 28, 1981. Memorandum. 32 Page(s).
John Doherty. Toxicology Branch.
EPA No. 10182-EUP-19 and PP 1G2461 and FAP 1H5287, Experimental Use Permit
and Temporary Tolerances for Synthetic Pyrethrin Cypermethrin on Cottonseed,
Cottonseed Hulls and Cottonseed Oil. Pages 27-32 removed, draft label.
Tox Review 004825.
Document (PDF) (2508 KB PDF).

February 09, 1982. Memorandum. 6 Page(s).
Andrew Rathman. Chemistry Branch.
Cypermethrin on cotton. Evaluation of amendment dated 9/9/81 including revised
Sections B and F. Pages 5-6 not included - Confidential Statement of Formula.
Document (PDF) (272 KB PDF).

February 17, 1982. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
Cypermethrin. Spray drift protocol.
Document (PDF) (75 KB PDF).

April 01, 1982. Data Eval. Rec. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr static acute LC50 test; Rainbow Trout Acc. 070562. MRID 00089037.
Document (PDF) (136 KB PDF).

April 05, 1982. Data Eval. Rec. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr static acute LC50 test; Bluegill sunfish Acc. 070562. MRID 00089038.
Document (PDF) (134 KB PDF).

April 07, 1982. Data Eval. Rec. 2 Page(s).
Thomas Johnston. Ecological Effects Branch.
Embryo-larvae flow through; Fathead minnow Acc. 070562. MRID 00089039.
Document (PDF) (86 KB PDF).

April 08, 1982. Data Eval. Rec. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
1, 2, 4, 9, 20, and 24-hr EC50 and LC50, freshwater aquatic invertebrates.
Acc. 070562.
Document (PDF) (143 KB PDF).

April 09, 1982. Data Eval. Rec. 7 Page(s).
Thomas Johnston. Ecological Effects Branch.
Static acute 48-hr EC50s; Daphnia magna. Acc. 070562.
Document (PDF) (307 KB PDF).

April 12, 1982. Data Eval. Rec. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr flow-through toxicity test; crayfish Acc. 070562.
Document (PDF) (130 KB PDF).

April 12, 1982. Data Eval. Rec. 7 Page(s).
Thomas Johnston. Ecological Effects Branch.
Acute toxicity in flow-through system (96-hr EC50 and LC50);
Freshwater shrimp and mayfly larvae. Acc. 070562.
Document (PDF) (320 KB PDF).

April 13, 1982. Data Eval. Rec. 2 Page(s).
Thomas Johnston. Ecological Effects Branch.
48-hr static acute EC50; Daphnia magna Acc. 070562.
Document (PDF) (81 KB PDF).

April 13, 1982. Data Eval. Rec. 2 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr acute LC50 under flow-through conditions; Fiddler crabs.
Acc. 070562. MRID 00089045.
Document (PDF) (70 KB PDF).

April 14, 1982. Data Eval. Rec. 3 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr acute flow-through LC50 and EC50; Mayfly Acc. 070562.
Document (PDF) (102 KB PDF).

April 14, 1982. Data Eval. Rec. 4 Page(s).
Thomas Johnston. Ecological Effects Branch.
96-hr shell deposition EC50; Eastern oyster Acc. 070562. MRID 00089049.
Document (PDF) (441 KB PDF).

April 27, 1982. Review. 13 Page(s).
Thomas Johnston. Ecological Effects Branch.
Proposed full registration of cotton use.
Document (PDF) (676 KB PDF).

April 29, 1982. Review. 91 Page(s).
Willa Garner. Environmental Fate Branch.
File Nos. 10182-AL, 10182-AU. Cymbush. Registration of New Insecticide
Chemical for Use on Cotton.
Document (PDF) (4541 KB PDF).

May 14, 1982. Review. 7 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 10182-AL. Cymbush. Rotational Crop Studies Acc. 247111.
Document (PDF) (252 KB PDF).

October 08, 1982. Memorandum. 12 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 10182-EUP-GE, FAP 2H5362. Request for EUP and for Establishing
a Food Additive Tolerance of 0.05 ppm in/on (All) Foods, Resulting From
Application of Cypermethrin... Pages 6-10 removed, draft label.
Pages 11-12 removed, CSF. Tox review 00221.
Document (PDF) (650 KB PDF).

December 22, 1982. Memorandum. 33 Page(s).
John Doherty. Toxicology Branch.
PP 2F2623 and FAP 2H5334. Request for a Tolerance for Cypermethrin on Cottonseed,
and in Meat and Milk. EPA Registrations 10182-AL and 10182-AU for Cymbush 2E
(Preparation GFU-070) and Cymbush 3E... Tox review 002391.
Inert info on page 4 not included.
Document (PDF) (4511 KB PDF).

May 04, 1983. Review. 5 Page(s).
Richard Moraski. Exposure Assessment Branch.
File No. 279-GNET. Ammo 2.5 EC. Review New Uses - Use on Tomatoes and Lettuce.
Document (PDF) (170 KB PDF).

May 19, 1983. Memorandum. 3 Page(s).
David Coppage. Ecological Effects Branch.
1. Ammo 2.5 EC (Cypermethrin), Proposed full registration for lettuce use. 2. Ammo
2.5 EC (Cypermethrin), Proposed full registration of Tomato use.
Document (PDF) (124 KB PDF).

June 07, 1983. Memorandum. 2 Page(s).
John Doherty. Toxicology Branch.
EPA Registration No. 10182-EUP-19. Nitrosamine Contamination of Pesticide Products
Containing Cypermethrin. Manufacturing process info on pages 1 and 2 is not included.
TXR No. 007707.
Document (PDF) (125 KB PDF).

September 16, 1983. Memorandum. 28 Page(s).
John Doherty. Toxicology Branch.
PP #2F2623 and FAP #2H5334 Concerning Cypermethrin on Cotton and Related Tolerances.
Tox review 003249.
Document (PDF) (4119 KB PDF).

September 27, 1983. Review. 4 Page(s).
Richard Moraski. Exposure Assessment Branch.
File No. 10182-TR. Demon WP. Review Label and Proposed Use for Control of
Cockroaches in, on and around Buildings. Page 4 is not included - draft label.
Document (PDF) (136 KB PDF).

November 30, 1983. Memorandum. 5 Page(s).
John Doherty. Toxicology Branch.
EPA Registration No. 10182-TR. Registrant's Response to Toxicology Branch's
Questions Concerning Gross Pathology Reports and Clinical Responses for an
Acute Oral LD50 Study with the Product Demon... Pages 3-5 removed, draft label.
Tox review 003399.
Document (PDF) (187 KB PDF).

February 06, 1984. Review. 5 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 10182-AL. Cymbush 2EC. Review Data on File to Support Use on Pecans.
Pages 4-5 removed, draft label.
Document (PDF) (158 KB PDF).

February 14, 1984. Review. 6 Page(s).
Wayne Faatz. Ecological Effects Branch.
Proposed registration of pecans use.
Document (PDF) (322 KB PDF).

February 21, 1984. Memorandum. 7 Page(s).
John Doherty. Toxicology Branch.
PP #2F2623 and FAP #2H5334. Toxicology Branch Update on the Mouse
Oncogenicity Study and Dog Chronic Feeding Study, Cypermethrin.
Tox review 003647.
Document (PDF) (755 KB PDF).

March 01, 1984. Review. 17 Page(s).
John Doherty. Toxicology Branch.
Cypermethrin: Assessment of Chronic and Oncogenic Effects. A Summary.
Document (PDF) (1404 KB PDF).

March 02, 1984. Memorandum. 6 Page(s).
Wayne Faatz. Ecological Effects Branch.
File No. 10182-AL, 10182-AU, 10182-IN. Cymbush 3E, Cymbush 2E, Cymbush OL
Registrant response concerning aquatic field study.
Document (PDF) (398 KB PDF).

March 02, 1984. Review. 9 Page(s).
Robert Hitch. Exposure Assessment Branch.
Exposure assessment for cotton field applicators in response to a request
by the Toxicology Branch.
Document (PDF) (556 KB PDF).

March 27, 1984. Memorandum. 6 Page(s).
Edwin Budd. Toxicology Branch.
PP #2F2623. Cypermethrin in/on Cottonseed, Meat and Milk. Risk Assessment.
Tox review 004466.
Document (PDF) (537 KB PDF).

April 02, 1984. Review. 6 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Registration of new use on cabbage.
Document (PDF) (253 KB PDF).

April 18, 1984. Review. 6 Page(s).
Clayton Bushong. Ecological Effects Branch.
Proposed registration of cabbage use.
Document (PDF) (288 KB PDF).

April 26, 1984. Review. 6 Page(s).
Clayton Bushong. Ecological Effects Branch.
Registrant's rebuttal to previous EEB review of aquatic field study.
Document (PDF) (425 KB PDF).

May 02, 1984. Memorandum. 12 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 279-GNET: Change in Formulation. Review of Acute Toxicity Studies
to Support Labeling. Inert ingredient information on pages 1 and 5 not included.
Pages 7-12 removed, draft label. Tox review 003798.
Document (PDF) (571 KB PDF).

May 17, 1984. Review. 2 Page(s).
Robert Hitch. Exposure Assessment Branch.
ICI Americas Inc... responded to an unfavorable Toxicology Branch Risk Assessment
(27 March 1984)...
Document (PDF) (78 KB PDF).

June 19, 1984. Review. 10 Page(s).
Carolyn K. Offutt. Enviromental Processes & Guidelines.
Estimated enviromental concentration review of Cypermethrin Reg./File No. 10182-AL.
EEC Aquatic Exposure for Ecological Effects Branch.
Document (PDF) (508 KB PDF).

July 06, 1984. Memorandum. 5 Page(s).
John Whalan. Toxicology Branch.
Registration of Ammo 2.5 Oil for Use on Cotton. Active Ingredient is Cypermethrin;
Accession No. 252997; EPA File No. 279-GNUU. Inert ingredient information on pages 2,
5 not included. Tox Review 003867.
Document (PDF) (610 KB PDF).

July 09, 1984. Memorandum. 4 Page(s).
Clayton Bushong. Ecological Effects Branch.
Submission of aquatic field effects protocol for Cypermethrin.
Document (PDF) (212 KB PDF).

July 18, 1984. Review. 2 Page(s).
Carolyn K. Offutt. Enviromental Processes & Guidelines.
Estimated environmental concentration review of Cypermethrin. EEC for use on pecans.
Document (PDF) (56 KB PDF).

July 20, 1984. Review. 13 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Cypermethrin. EPA Reg. No. 10182-80 and -68. FMC Corp.
Request Waiver from Field Dissipation Study of Soil Degradation Products.
Pages 9-13 removed, registrant data.
Document (PDF) (440 KB PDF).

August 17, 1984. Review. 2 Page(s).
Joe Reinert. Exposure Assessment Branch.
Cypermethrin. Submission of modified label.
Document (PDF) (77 KB PDF).

August 22, 1984. Review. 2 Page(s).
Joe Reinert. Exposure Assessment Branch.
Cypermethrin. Label Modification.
Document (PDF) (85 KB PDF).

September 13, 1984. Review. 5 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg./File No : 10182-TR ICI Exposure Assessment.
Document (PDF) (177 KB PDF).

October 12, 1984. Memorandum. 3 Page(s).
Karen Hamernik. Toxicology Branch.
Request for applicator exposure information for the propose use of Cypermethrin on pecans.
Page 2 not included.- Draft Label.
Document (PDF) (137 KB PDF).

October 23, 1984. Review. 7 Page(s).
Samuel Creeger. Environmental Assessment Branch.
EPA Reg. No. 279-3027. Cypermethrin. FMC Corporation. Review Field Dissipation Studies.
Document (PDF) (277 KB PDF).

November 30, 1984. Review. 5 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg./File No: 279-3046 ICI Americas, Inc. Appicator Exposure Monitoring Field Study.
Document (PDF) (257 KB PDF).

February 11, 1985. Review. 2 Page(s).
Joe Reinert. Exposure Assessment Branch.
Cypermethrin. Exposure Data.
Document (PDF) (64 KB PDF).

May 16, 1985. Review. 14 Page(s).
Joe Reinert. Exposure Assessment Branch.
Review of exposure assessment submitted by ICI- Americas and calculation of exposure assessment.
Document (PDF) (792 KB PDF).

June 06, 1985. Review. 16 Page(s).
Joe Reinert. Exposure Assessment Branch.
Reg./File No.: 10182-TR Applicator and Resident Exposure Analysis.
Document (PDF) (641 KB PDF).

June 17, 1985. Review. 16 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg./File No: 10182-TR ICI Americas Applicator and Resident Exposure Assessment.
Document (PDF) (695 KB PDF).

July 22, 1985. Review. 8 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg./File No: 10182-64 ICI Americas Review of letter submitted by ICI Americas.
Document (PDF) (447 KB PDF).

August 26, 1985. Review. 8 Page(s).
Joseph C. Reinert. Special Review Section.
EAB review of Cypermethrin, ICI Americas, Review of letter submitted by ICI Americas.
Document (PDF) (458 KB PDF).

December 04, 1985. Review. 12 Page(s).
Emil Regelman. Exposure Assessment Branch.
EPA Reg. No. 10182-65. Cypermethrin. FMC Corporation. Review/Evaluation
Field Dissipation Study: New Uses, Registration for Cabbage and Lettuce.
Document (PDF) (358 KB PDF).

February 28, 1986. Review. 11 Page(s).
Allen Vaughan. Environmental Effects Branch.
Cypermethrin. Honey bee acute contact and oral LD50.
Document (PDF) (699 KB PDF).

March 04, 1986. Memorandum. 5 Page(s).
Thomas Armitage. Ecological Effects Branch.
Submission of Cypermethrin Data/Information in response to data call-in notice.
Document (PDF) (262 KB PDF).

April 03, 1986. Review. 2 Page(s).
Joseph C. Reinert. Special Review Section.
EAB review of Cypermethrin. Proposed change in packaging.
Document (PDF) (52 KB PDF).

May 19, 1986. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
PP #2F2623: Cypermethrin. Registrant's Request to Toxicology Branch to
Reconsider the NOEL for the Dog 1-Year Dosing Study Set at 1.0 mg/kg/day
Based on Increased Incidences of Liquid Stools. Tox review 005159.
Document (PDF) (429 KB PDF).

June 18, 1986. Memorandum. 3 Page(s).
Allen Vaughan. Ecological Effects Branch.
Review of protocol for toxicity testing on honey bees.
Document (PDF) (148 KB PDF).

July 11, 1986. Review. 4 Page(s).
Michael Slimak. Ecological Effects Branch.
Submission of aquatic laboratory studies protocols for review relative
to DCI notices of October 25, 1985.
Document (PDF) (179 KB PDF).

January 16, 1987. Memorandum. 15 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 279-3026 and 279-3027 Cypermethrin: Update on the presence of
hydrogen cyanide in the headspace of the products AMMO Technical Insecticide
and AMMO 2.5 EC Insecticide.
Document (PDF) (762 KB PDF).

February 17, 1987. Memorandum. 4 Page(s).
Ann Stavola. Ecological Effects Branch.
Response by ICI Americas, Inc. to Ecological Effects Branch comments on July 3,
1986 regarding protocols for fish life cycle study and mysid acute and chronic
toxicity studies with Permethrin and Cypermethrin.
Document (PDF) (186 KB PDF).

April 16, 1987. Memorandum. 5 Page(s).
Michael Slimak. Ecological Effects Branch.
Registrant request for concurrence on Aquatic Testing Phone Discussion of 2-25-87.
Document (PDF) (216 KB PDF).

June 11, 1987. Memorandum. 16 Page(s).
Bernice Fisher. Toxicology Branch.
Cypermethrin, Mouse Study Females Qualitative Risk Assessment - Reevaluation
with Historical Controls. Pages 7-16 removed, registrant data. Tox review 006511.
Document (PDF) (447 KB PDF).

June 12, 1987. Review. 8 Page(s).
Michael Firestone. Exposure Assessment Branch.
Inhalation Exposure for Cypermethrin.
Document (PDF) (241 KB PDF).

June 19, 1987. Memorandum. 9 Page(s).
Reto Engler. Toxicology Branch.
Second Peer Review on Cypermethrin. TXR No. 007707.
Document (PDF) (713 KB PDF).

January 13, 1988. Review. 9 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. File # 279-3026/3027 FMC Corporation Review of Air Monitoring Data.
Document (PDF) (517 KB PDF).

February 17, 1988. Memorandum. 11 Page(s).
John Quest. Toxicology Branch.
Peer Review of Cypermethrin. TXR No. 007707.
Document (PDF) (762 KB PDF).

February 19, 1988. Review. 19 Page(s).
Ann Stavola. Ecological Effects Branch.
Proposed registration for use on bulb onion and garlic.
Pages 8-16 not included-Draft Label.
Document (PDF) (484 KB PDF).

February 26, 1988. Review. 1 Page(s).
John Jordan. Exposure Assessment Branch.
Meeting with FMC (2/3/88) to consider the registration of improved
isomers to replace the present product.
Document (PDF) (58 KB PDF).

March 14, 1988. DER. 3 Pages.
Allen Vaughan. Ecological Effects Branch.
Honey bee - toxicity of residues on foliage. Species Tested: Apis mellifera.
EPA Acc. No. 402740-01. EPA Reg. Nos. 10182-64, -65, -80.
Document (PDF) (129 KB PDF).

March 15, 1988. Review. 6 Page(s).
Allen Vaughan. Ecological Effects Branch.
Submission of honey bee data (residual toxicity study) for review.
Document (PDF) (248 KB PDF).

March 24, 1988. Review. 7 Page(s).
Michael Firestone. Special Review Section.
Reg. No. 10182-107, 10182-108. Exposure Assessment. Revised exposure assessment
for residents of homes treated with cypermethrin for subterranean termite control.
Document (PDF) (259 KB PDF).

March 28, 1988. Memorandum. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
10182-65, 10182-64, 10182-80 Progress report on fish full-life cycle study.
Document (PDF) (97 KB PDF).

March 28, 1988. Memorandum. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
10182-65, 10182-64, 10182-80 Submission of progress report on fish full-life cycle study.
Document (PDF) (97 KB PDF).

March 28, 1988. Review. 2 Page(s).
Ann Stavola. Ecological Effects Branch.
10182-65, 10182-64, 10182-80 Submission of preliminary fish full-life cycle study
results in response to DCI notice of 10-25-85. Acc. 401021-01.
Document (PDF) (101 KB PDF).

April 14, 1988. Memorandum. 2 Page(s).
Thomas Dixon. Exposure Assessment Branch.
Possibility of registering Cypermethrin-Minus by bridging the Cypermethrin
Environmental Fate Data.
Document (PDF) (83 KB PDF).

April 22, 1988. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. Nos. 10182-64, -65, -68, -80. Cymbush. Evaluation of Protocol.
Document (PDF) (135 KB PDF).

August 16, 1988. Review. 4 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. # 279-3026, -3027. Evaluation of data requirements for product with
improved isomer spectrum (Cypermethrin-minus).
Document (PDF) (191 KB PDF).

February 16, 1989. Memorandum. 5 Page(s).
James Akerman. Ecological Effects Branch.
EEB's review of the Cypermethrin fish full life cycle study conducted by ICI
Americas, Inc. in response to the data call-in notice of October 25, 1985.
(EPA Accession No. 406417-01).
Document (PDF) (322 KB PDF).

March 22, 1989. Memorandum. 2 Page(s).
Michael Firestone. Non-Dietary Exposure Branch.
Expedited Review of Cypermethrin Contamination of Bifenthrin -
Human Non-Dietary Exposure Concerns.
Document (PDF) (81 KB PDF).

May 17, 1989. Memorandum. 7 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg. No./File Symbol 279-GNIR Cynoff 2 EC Insecticide.
MRID 406809-02 thru 06. Tox Review 009109.
Document (PDF) (480 KB PDF).

June 13, 1989. Review. 124 Page(s).
James Akerman. Ecological Effects Branch.
Submission by FMC Corp. and ICI Americas, Inc. of Modifications
for the Cypermethrin Mesocosm Protocol.
Document (PDF) (6686 KB PDF).

July 26, 1989. Memorandum. 5 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg no./File Symbol 279-GNIR; Cynoff 2 EC Insecticide.
MRID 411152-01; acute inhalation. Tox Review 009107.
Document (PDF) (265 KB PDF).

September 19, 1989. Efficacy Review. 1 Page(s).
Vern McFarland. Insecticide Rodenticide Branch.
File No. 279-GNIE. Cynoff FT Termiticide. Provide Revised Labeling Reflecting Use
of 0.3% to 0.6% Active Ingredient in All Applications, Based on Additional Efficacy
Data Registrant Received.
Document (PDF) (86 KB PDF).

November 14, 1989. Review. 1 Page(s).
Vern McFarland. Insecticide Rodenticide Branch.
Efficacy Review, Reg No. 279-3070, 2070-3085. Provide amended labeling for the
purpose of clarifying the directions for use and addition of pests claimed indoors
and outdoors, including fire ants.
Document (PDF) (78 KB PDF).

January 10, 1990. Review. 4 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Reg. No. 10182-105. Demon EC Insecticide. Amendment to Add Use for Treatment
of Preconstruction Lumber and Logs.
Document (PDF) (174 KB PDF).

January 30, 1990. Review. 7 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Evaluate reistrant reguest for waiver of data requirements for Cypermethrin-Minus.
Document (PDF) (209 KB PDF).

February 02, 1990. Review. 193 Page(s).
John Doherty. Insecticide Rodenticide Branch.
Ad Hoc Peer Review of Cypermethrin-Minus. Pages 56-85, 94-104 not included - Registration Data.
Information on pages 122-123 deleted - Manufacturing process information.
Document (PDF) (49212 KB PDF).

April 06, 1990. Review. 5 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Cypermethrin. Application for E.U.P.
Document (PDF) (178 KB PDF).

July 09, 1990. Memorandum. 6 Page(s).
Olga Odiott. Registration Support Branch.
EPA Reg. No./File Symbol 10182-RUN Cypermethrin 70% Technical.
Pages 4-6 removed, draft label. MRID 413036-01; acute inhalation.
Tox Review 009013.
Document (PDF) (183 KB PDF).

November 26, 1990. Memorandum. 9 Page(s).
Sheila Moats. Registration Support Branch.
EPA Reg. No. /File Symbol 279-GRNO Cynoff R 50 WP MRID 416290-02 thru 07;
acute studies. Tox review 008632.
Document (PDF) (529 KB PDF).

November 30, 1990. Data Eval. Rec. 3 Page(s).
Ann Stavola. Ecological Effects Branch.
Continuous flow 96-hr LC50; Bluegill sunfish MRID 00065812.
Document (PDF) (129 KB PDF).

November 30, 1990. Data Eval. Rec. 3 Page(s).
Ann Stavola. Ecological Effects Branch.
Continuous flow 96-hr LC50; Rainbow trout. MRID 00062792.
Document (PDF) (125 KB PDF).

December 19, 1990. Data Eval. Rec. 3 Page(s).
Ann Stavola. Ecological Effects Branch.
Continuous flow 96-hr LC50; Rainbow trout. MRID 00065813.
Document (PDF) (121 KB PDF).

January 04, 1991. Data Eval. Rec. 4 Page(s).
Ann Stavola. Ecological Effects Branch.
Acute flow-through toxicity test. Pink shrimp. Acc. 070562. MRID 00089043.
Document (PDF) (198 KB PDF).

January 08, 1991. Data Eval. Rec. 3 Page(s).
Ann Stavola. Ecological Effects Branch.
96-hr flow-through acute toxicity test. Sheepshead minnows. Acc. 070561.
MRID 00090075.
Document (PDF) (145 KB PDF).

January 09, 1991. Review. 7 Page(s).
Ann Stavola. Ecological Effects Branch.
The effect of dietary inclusion of cypermethrin on reproduction in the bobwhite quail.
MRID 00090074.
Document (PDF) (245 KB PDF).

January 10, 1991. Data Eval. Rec. 7 Page(s).
Ann Stavola. Ecological Effects Branch.
Estuarine invertebrate acute toxicity Mysidopsis bahia. MRID 92027-021.
Document (PDF) (332 KB PDF).

January 10, 1991. DER. 11 Pages.
Ann Stavola. Ecological Effects Branch.
AMENDMENT TO DER BY T. JOHNSTON, 4/13/82. Daphnia 21-day chronic toxicity
Daphnia magna (first instar). MRID 92027-025, and MRID 00089047.
Document (PDF) (509 KB PDF).

January 10, 1991. Review. 3 Page(s).
Charles Lewis. Ecological Effects Branch.
The subacute dietary toxicity (LC50) of cypermethrin (PP383) to the mallard duck.
MRID 92027-004, 00090071.
Document (PDF) (119 KB PDF).

January 10, 1991. Review. 3 Page(s).
Charles Lewis. Ecological Effects Branch.
The subacute dietary toxicity (LC50) of Cypermethrin to the bobwhite quail.
MRID 92027-003, 00090072.
Document (PDF) (121 KB PDF).

March 07, 1991. Review. 13 Page(s).
Bruce F. Kitchens. Environmental Chemistry Review Section 3.
Review of phase 4 package for the list B chemical Cypermethrin, Case No. 2130.
Document (PDF) (739 KB PDF).

September 30, 1991. Memorandum. 9 Page(s).
Ian Blackwell. Registration Support Branch.
EPA Reg. No./File Symbol 279-GREN Cynoff 2.5 EW Insecticide; 279-GRRI Prevail
4.0 Termiticide. Acute studies. Inert ingredient on page 2 not included.
MRID 418176-01, 417865-02 thru 06. Tox review 009135.
Document (PDF) (421 KB PDF).

December 02, 1991. Memorandum. 14 Page(s).
William Greear. Toxicology Branch.
Cypermethrin-S: Experimental Use Permit for the Use of FMC 56701 1.5 EC/EW
Insecticide on Cotton, Lettuce and Beans - FINAL REPORT (EPA ID No. 279-EUP-REA)
MRID 41776102. Tox review 008865 (excerpt).
Document (PDF) (639 KB PDF).

December 02, 1991. Memorandum. 26 Page(s).
William Greear. Toxicology Branch.
Cypermethrin-S: Experimental use permit for the use of FMC 56701 1.5 EC/EW
insecticide on cotton, lettuce and beans- Final Report (EPA ID No. 279-EUP-REA).
Tox review 008865.
Document (PDF) (1187 KB PDF).

December 10, 1991. Review. 3 Page(s).
Akiva Abramovitch. Environmental Fate & Ground Water Branch.
Petition for Emergency Exemption use on sugarbeets by California.
Document (PDF) (133 KB PDF).

February 13, 1992. Data Eval. Rep.. 14 Page(s).
John Doherty. Toxicology Branch.
Study Type: 83-4. Multi generation reproduction study - rats
MRID NO.: 419682-04 Tox review (excerpt) 009347.
Document (PDF) (854 KB PDF).

March 06, 1992. Memorandum. 10 Page(s).
John Doherty. Toxicology Branch.
EPA Id No.: 279-GREU and 000279-3027. Cypermethrin-S (FMC 56701): Application
for registration of the technical product and 1.5 EC Insecticide and 1.5 EW
Insecticide for registration on cotton, lettuce and pecans. Require- (continued).
Document (PDF) (552 KB PDF).
Attachment(s) Following:

March 06, 1992. Memorandum.
John Doherty. Toxicology Branch.
(cont.) ment for special neurotoxicity testing for cymermethrin and cypermethrin-S.
MRID 41968204. Tox review 009347 (excerpt).

*End of Attachments*

April 06, 1992. Memorandum. 63 Page(s).
Doug Urban. Ecological Effects Branch.
Data review for Cypermethrin minus (129064) and Cypermethrin. Pages 9-10, 16-17,
24-29, 37-38, 46-51, 58-61 removed, registration data. MRID 41968208 thru 41968213.
Document (PDF) (2804 KB PDF).

June 08, 1992. Review. 93 Page(s).
Akiva Abramovitch. Environmental Chemistry Review/EFGWB.
EFGWB review of Cypermethrin. Review of photodegredation in water and on soil,
and mobility studies. Pages 14-27, 33-46, 50-64, 71-89 removed, registration data.
MRID 42129002, 42141501, 42129001, 42129003.
Document (PDF) (2056 KB PDF).

July 01, 1992. Summary. 5 Page(s).
Toxicology Branch..
Free Standing Toxicology Summary: Cypermethrin. Tox Chem No. 271DD.
Document (PDF) (255 KB PDF).

August 02, 1992. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
EPA ID# 109702-000279. Cypermethrin: Response to Submission of Historical
Control Data for the Dermal Sensitization (Series 81-6) Study. Tox Chem No: 271DD.
Document (PDF) (181 KB PDF).

September 23, 1992. Memorandum. 1 Page(s).
Doug Urban. Ecological Effects Branch.
Response to comments submitted by FMC Corp. for Cypermethrin minus (129064)
and Cypermethrin (109702).
Document (PDF) (57 KB PDF).

October 05, 1992. Memorandum. 6 Page(s).
Doug Urban. Ecological Effects Branch.
Review study which is revised report of MRID 419682-12 on cypermethrin (109702).
Document (PDF) (1498 KB PDF).

October 07, 1992. Memorandum. 4 Page(s).
Ian Blackwell. Registration Support Branch.
EPA File symbol/ EPA Reg. No.: 279-GRRI/ Prevail 4.0 Termiticide.
MRID 417865-03, acute inhalation. Tox review 009920.
Document (PDF) (170 KB PDF).

October 09, 1992. Review. 8 Page(s).
Ann Stavola. Ecological Effects Branch.
The acute oral toxicity (LD50) of Cypermethrin to the Mallard duck.
Pages 7-8 removed, Registration Data. MRID 90070.
Document (PDF) (371 KB PDF).

November 12, 1992. Review. 10 Page(s).
Henry Craven. Ecological Effects Branch.
Determination of the acute toxicity of formulation GFU 070 to Rainbow Trout
(Salmo gairdneri). Pages 7-9 removed, Registration Data. MRID 88947.
Document (PDF) (429 KB PDF).

November 12, 1992. Review. 14 Page(s).
Henry Craven. Ecological Effects Branch.
Determination of the acute toxicity of formulation GFU to Bluegill
(Lepomis macrochirus). Pages 7-14 removed, Registration Data. MRID 88948.
Document (PDF) (428 KB PDF).

November 12, 1992. Review. 9 Page(s).
Henry Craven. Ecological Effects Branch.
Freshwater Invertebrate Static Acute Toxicity Test: Daphnia magna.
Pages 6-7 removed, Registration Data. MRID 152739.
Document (PDF) (361 KB PDF).

February 02, 1993. Report. 102 Page(s).
Tom Bailey. Ecological Effects Branch.
Cypermethrin. Aquatic Mesocosm Study. Palmieri, M., et al. An Evaluation of the
Impact of Cypermethrin Exposure on Managed Aquatic Ecosystems. FMC Study No. A89-2847.
Document (PDF) (5879 KB PDF).

February 02, 1993. Review. 5 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
MRID No. 421482-01, vols 1-5. Review of Cypermethrin Mesocosm Study on Cotton,
Pecans and Lettuce.
Document (PDF) (403 KB PDF).

April 19, 1993. Memorandum. 4 Page(s).
John Doherty. Toxicology Branch.
EPA Id#: 000270-ELG and 00270-ELN. Farnam Crash! Wip on Insecticide/Repellent
and Farnam Crash! Fly spray concentrate. Review of a domestic animal safety
study with horses. MRID 436579-01. Tox review 010166.
Document (PDF) (277 KB PDF).

June 10, 1993. Memorandum. 10 Page(s).
John Doherty. Toxicology Branch.
EPA Id. No.: 000279-03124. S-Cypermethrin (Fury): Review of a in vivo chromosomal
aberrations study in rat bone marrow. Pages 8-10 removed, registration data.
MRID 427586-01. Tox review 010323.
Document (PDF) (391 KB PDF).

November 10, 1993. Review. 214 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Review of 161-1,2,3; 161-1,2; 163-1, & 164-1 studies for reregistration.
Also, proposed new use on tomatoes.
Pages 18-44, 52-63, 69-89, 95-111, 118-135, 139-155, 162-182, 191-208 removed, RD.
MRID 42620501, 42129001, 02, 03, 42156601, 02, 42395701, 42549601.
Document (PDF) (4486 KB PDF).

January 24, 1994. Review. 20 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Review study conducted with cypermethrin and zetacypermethrin.
Pages 10-20 removed, Registration Data. 424446-01.
Document (PDF) (504 KB PDF).

April 19, 1994. Review. 5 Page(s).
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Protocol for conducting VFS pyrethroid runoff studies.
Document (PDF) (323 KB PDF).

May 23, 1994. Memorandum. 4 Page(s).
G. F. Kramer. Chemistry Branch I.
ID# 039039-00004. Registration of Python Insecticide Cattle Ear Tag (Cyprmethrin,
Piperonyl butoxide). MRID#s 425511-08 & -09. Barcode D185396. Case 015542. CBTS# 11035.
Document (PDF) (207 KB PDF).

December 29, 1994. DER. 12 Pages.
Renee Lamb. Ecological Effects Branch.
Early life stage toxicity test with the mysid (Mysidopsis bahia). MRID No. 427253-01.
Document (PDF) (845 KB PDF).

January 10, 1995. Review. 15 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
FMC Corporation study review- mysid life cycle. MRID No. 427253-01.
Document (PDF) (875 KB PDF).

January 25, 1995. Review. 1 Page(s).
Ronald Parker. Environmental Fate & Ground Water Branch.
To complete refined aquatic exposure assessments through computer modelling for
Lambdacyhalothrin, Cyfluthrin, Cypermethrin, Esfenvalerate, Tralomethrin, Bifenthrin,
and Permethrin, through review of aquatic mesocosm studies through review of pond studies.
Document (PDF) (69 KB PDF).

March 04, 1996. Review. 63 Page(s).
Akiva Abramovitch. Environmental Fate & Ground Water Branch.
Review of 165-4 study for registration, status of data requirements,
and New Use Registration requests for tomatoes and Brassica crops.
Pages 16-55 removed, Registration Data. 42868201.
Document (PDF) (1823 KB PDF).

July 02, 1996. Memorandum. 8 Page(s).
Virginia Dobozy. Occupational & Residential Exposure Branch.
Cypermethrin - Review of Pesticide Poisoning Incident Data.
Document (PDF) (507 KB PDF).

September 18, 1996. Memorandum. 142 Page(s).
John Doherty. Toxicology Branch.
EPA Id No.: 109702-019182. Cypermethrin: Review of the rat metabolism studies
with C14 label in the aryl or cyclopropyl positions. Executive Summaries and updated
DERs for 10 older toxicity studies. Tox review 012057. (continued).
Document (PDF) (5779 KB PDF).
Attachment(s) Following:

September 18, 1996. Memorandum.
John Doherty. Toxicology Branch.
Tox review 012057 (continued). Pages 16-17, 26, 31-35, 39-40, 45-47, 54-61, 75-
77, 81-85, 90-94, 101-109, 114-119, 128-142 removed, registrant data.
MRID 41551104, 41551103, 00056802, 92027034, 00112929, 00090035, 00112909,
42068503, 92027037 (continued).

September 18, 1996. Memorandum.
John Doherty. Toxicology Branch.
Tox review 012057 (continued) MRID 00112911, 92027038, 00056804, 92027039,
92027061, 00056805, 00112912, 42068504, 92027040, 00090040, 00112910.

*End of Attachments*

September 18, 1996. Memorandum. 30 Page(s).
John Doherty. Toxicology Branch I.
EPA Id No.: 109702. Cypermethrin: Review of a series 82-4 subchronic inhalation
toxicity study in rats and a series 83-3 developmental toxicity study in rabbits.
Pages 17-18 removed, registrant data. Tox review 012056.
MRID 43507101, 43776301, 43776302.
Document (PDF) (1823 KB PDF).

October 15, 1996. Memorandum. 28 Page(s).
Laura Morris. Occupational & Residential Exposure Br.
Occupational and residential Exposure Assessment and Recommendations
for the Reregistration Eligibility Decision Document for Cypermethrin.
Document (PDF) (1880 KB PDF).

October 29, 1996. Memorandum. 9 Page(s).
George Ghali. Health Effects Division.
RfD/Peer Review Report of Cypermethrin.
Document (PDF) (542 KB PDF).

January 15, 1997. Memorandum. 14 Page(s).
Brian Steinwand. Science Analysis Branch.
Dietary Exposure Analysis for Cypermethrin in Support of the Reregistration
Eligibility Decision. Attached: DRES.
Document (PDF) (702 KB PDF).

March 06, 1997. DER. 24 Page(s).
Miachel Rexrode. Ecological Effects Branch.
70-1 - Special Test: Acute Sediment Toxicity Test with a Freshwater Invertebrate
(Chironomus tentans). MRID 440744-02.
Document (PDF) (1127 KB PDF).

March 06, 1997. DER. 33 Page(s).
Miachel Rexrode. Ecological Effects Branch.
70-1 - Acute Sediment Toxicity Test with a Freshwater Invertebrate (Hyalella aztec)
MRID 440744-06.
Document (PDF) (1420 KB PDF).

November 14, 1997. Memorandum. 13 Page(s).
Jess Rowland. Science Analysis Branch.
SYNTHETIC PYRETHROIDS - REVISED Report of the Hazard Identification Assessment Review Committee.
Document (PDF) (814 KB PDF).

November 14, 1997. Memorandum. 170 Page(s).
P. Hurley et. al. RAB2/HED.
Risk Assessment for Extension of Tolerances for Synthetic Pyrethroids.
Document (PDF) (7583 KB PDF).
Attachment(s) Following:

October 18, 1997. Memorandum.
Jess Rowland. Science Analysis Branch, HED.
Synthetic Pyrethroids - Report of the Hazard Identification
Assessment Review Committee (Attachment 1, page 3).

November 12, 1997. Memorandum.
Karl Baetcke.
Clarefication of Data Requirements for Pyrethroids and
Documentation of Decision Logic Applied to Determination
of Appropriate Uncertainty Factors for Infants and Children.
(Attachment 1, Appendix A, page 17).

September 12, 1997. Note.
David Brassard. Biological Analysis Branch, BEAD.
Review of Pyrethroid Working Group Percent Crop Treated
Estimates (Attachment 3, page 29).

October 8, 1997. Note.
David Brassard. Biological Analysis Branch, BEAD.
Review of Pyrethroid Working Group Percent Crop Treated
Estimates (page 35).

Undated. Memorandum.
Robert Matzner. Environmental Fate and Effects Division.
Preliminary Estimates of Synthetic Pyrethroid Drinking Water
Concentrations (Attachment 4, page 38).

Undated.
Non-Dietary Exposure and Risk Assessments for the Synthetic
Pyrethroids (Attachment 5, page 41).

Undated.
Bifenthrin. Toxicology and Residue Chemistry Details
(Attachment 6).

Undated.
Cyfluthrin. Toxicology and Residue Chemistry Details
(Attachment 7, page 106).

Undated.
Cyhalothrin. Toxicology and Residue Chemistry Details
(Attachment 8, page 128).

July 28, 1997. Review.
Jess Rowland. HED.
Toxicology Endpoint Selection Document; lambda-Cyhalothrin.

Undated.
Cypermethrin. Toxicology and Residue Chemistry Details
(Attachment 9, page 151).

*End of Attachments*

March 10, 2003. DER. 21 Pages.
Miachel Rexrode. Ecological Effects Branch.
AQUATIC INVERTEBRATE LIFE CYCLE TEST GUIDELINE 72-4 (B). [14C]b-Cypemethrin
-Chronic Toxicity to Mysids (Mysidopsis bahia) Under Flow-Through Conditions.
MRID No.: 445460-35. DP Barcode: D246502.
Document (PDF) (1358 KB PDF).

February 22, 2011. DER. 39 Pages.
Keith Sappington. OPP/EFED/ERBV.
MIDGE 60-DAY TOXICITY STUDY. Cypermethrin Life-Cycle Toxicity Test
with Midge (Chironomus tentans) During a 60-Day Sediment Exposure.
MRID No.: 46725701. DP Barcode: D325932.
Document (PDF) (297 KB PDF).

February 24, 2011. DER. 27 Pages.
Justin Housenger. OPP/EFED/ERB 5.
28-DAY WHOLE SEDIMENT Leptocheirus plumulosus TOXICITY TEST.
Cypermethrin Toxicity to Estuarine Amphipods (Leptocheirus plumulosus)
During a 28-Day Sediment Exposure. DP Barcode: D319265. MRID No.: 465915-03.
Document (PDF) (182 KB PDF).

February 24, 2011. DER. 36 Pages.
Amanda Solliday. OPP/EFED/ERB 5.
MIDGE 10-DAY TOXICITY STUDY. Cypermethrin - Toxicity to Midge
(Chironomus tentans) During a 10-Day Sediment Exposure.
MRID No.: 465915-04. DP Barcode: D319265.
Document (PDF) (245 KB PDF).

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