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Index of Cleared Science Reviews for Imazapyr and Imazapyr salts (Pc Code 128821)
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February 10, 1984. Review. 2 Page(s).
Bhushan Mandava. Reg. Support & Emergency Response Branch.
Product Chemistry Review on New Chemicals. Registration: 241-ETG.
Accession No.: 251500, 251501.
Document (PDF) (150 KB PDF).
February 17, 1984. Review. 4 Page(s).
Russel Farringer. Ecological Effects Branch.
File or Reg. No.: 241-ETG.
Proposed full registration of new product on noncropland areas.
Document (PDF) (264 KB PDF).
March 15, 1984. Review. 18 Page(s).
Samuel Creeger. Exposure Assessment Branch.
EPA Reg. No. 241-ETG. New chemical for use on non-cropland.
Document (PDF) (973 KB PDF).
March 21, 1984. Review. 4 Page(s).
Samuel Creeger. Exposure Assessment Branch.
EPA Reg. No. 241-EUP-RNR. Experimental use permit for non-cropland.
Document (PDF) (182 KB PDF).
June 18, 1984. Memorandum. 10 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg No. 241-ETG; Arsenal; New herbicide for non- cropland.
Accn. Nos. 251502, -503 & -504. Tox review No. 006997.
Document (PDF) (529 KB PDF).
June 18, 1984. Memorandum. 10 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg# 241-ETG. Arsenal; New herbicide for non- cropland. Caswell #: 003F
Accession #: 251502, 251503, 251504 Tox review 006997.
Document (PDF) (511 KB PDF).
June 18, 1984. Memorandum. 9 Page(s).
William Dykstra. Toxicology Branch.
241-EUP-RNR; Arsenal; New herbicide for non- cropland. Caswell #: 003F;
Accession #: 252004 (Addendum). Tox review 006998.
Document (PDF) (381 KB PDF).
November 21, 1984. Review. 3 Page(s).
Samuel Creeger. Environmental Assessment Branch.
Reg./file No.: 241-273. Review letter on waiver request (EUP on noncropland areas).
Document (PDF) (164 KB PDF).
November 27, 1984. Review. 3 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg./file No.: 241-EUP-RRU. Review forest dissipation study protocol.
Document (PDF) (149 KB PDF).
January 16, 1985. Review. 23 Page(s).
Raymond Matheny. Ecological Effects Branch.
File or Reg. No 241-EUP-RRU
Arsenal Herbicide Proposed EUP s for use in forestry applications.
Document (PDF) (747 KB PDF).
February 01, 1985. Review. 5 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg./File No.: 241-EUP-RRU. EUP for use on forests.
Document (PDF) (218 KB PDF).
May 01, 1985. Review. 4 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg./File No.: 241-273.
Registration for use on noncropland as a herbicide, resubmission.
Document (PDF) (153 KB PDF).
March 31, 1986. DER. 3 Pages.
Ann Stavola. Ecological Effects Branch.
Aquatic invertebrate acute toxicity test Daphnia magna. Static Acute
toxicity Report No. 32183. Acute Toxicity of AC 252,925 to Daphnia magna.
EPA Accession No. 258898. MRID No. 00147117.
Document (PDF) (75 KB PDF).
March 31, 1986. DER. 3 Pages.
Ann Stavola. Ecological Effects Branch.
Fish acute toxicity test Bluegill sunfish (Lepomis macrochius). Static Acute Toxicity
Report No. 32182. Acute Toxicity of AC 252,925 to Bluegill Sunfish (Lepomis macrochirus).
EPA Accession No. 258898. MRID No. 00147116.
Document (PDF) (79 KB PDF).
April 09, 1986. Review. 18 Page(s).
Curtis Laird. Ecological Effects Branch.
Reg. No 241-273. Submission of data to support full registration of use on noncropland areas.
Acc. 258898.
Document (PDF) (332 KB PDF).
October 03, 1986. Review. 13 Page(s).
Dynamac Corporation..
Arsenal Final Report Task 1: Review and Evaluation of Individual Studies
Task 2: Environmental Fate and Exposure Assessment.
Document (PDF) (598 KB PDF).
October 07, 1986. Review. 4 Page(s).
Emil Regelman. Exposure Assessment Branch.
EPA Reg. No. 241-273.
Submission of field dissipation and fish accumulation studies to fill data gaps.
Document (PDF) (160 KB PDF).
February 03, 1987. Memorandum. 5 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 241-EOI. Arsenal Herbicide Railroad Applicators Concentrate
Acute oral, acute dermal... Acc. 265948.
Document (PDF) (280 KB PDF).
February 19, 1987. Memorandum. 3 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 241-EOO. Arsenal Herbicide Applicator's Concentrate Dermal
sensitization, acute inhalation. MRID 400037-07, 08.
Document (PDF) (122 KB PDF).
April 21, 1987. Memorandum. 2 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA File Symbol 241-EOI. Arsenal Herbicide Railroad Applicators Concentrate.
Document (PDF) (36 KB PDF).
June 01, 1987. Review. 26 Page(s).
Charles Lewis. Ecological Effects Branch.
File or Reg. No. 241-EOO. Proposed Registration of Forestry Use.
Data Accession No(s).: 40003710, 40003711.
Document (PDF) (1203 KB PDF).
June 17, 1987. Review. 9 Page(s).
Therese Dougherty. Exposure Assessment Branch.
File or Reg. No. 241-EOO. Registration for Forestry (New Use).
Document (PDF) (357 KB PDF).
June 29, 1987. Review. 2 Page(s).
Michael Slimak. Ecological Effects Branch.
File or Reg. No 241-273.
Arsenal Herbicide Registrant response concerning endangered species labeling.
Document (PDF) (72 KB PDF).
July 02, 1987. Memorandum. 6 Page(s).
Mary Waller. Fungicide Herbicide Branch.
EPA Registration No. 241-295 Arsenal Herbicide 0.5G.
MRID 400703-01. Tox review 005993.
Document (PDF) (286 KB PDF).
September 25, 1987. Review. 17 Page(s).
Therese Dougherty. Exposure Assessment Branch.
Reg./File #: 241-EOO. Arsenal. Registration for Forestry (New Use).
MRID 40003714.
Document (PDF) (599 KB PDF).
April 14, 1988. Review. 3 Page(s).
Charles Lewis. Ecological Effects Branch.
Reg./File #: 241-EOO. Request to Waive Non-target Plant Data Requirements.
Document (PDF) (58 KB PDF).
September 15, 1988. Review. 9 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
EPA Reg. No. 241-296 Request for addition of forestry use to CHOPPER label.
Document (PDF) (448 KB PDF).
April 11, 1989. Memorandum. 26 Page(s).
Pamela Hurley. Toxicology Branch I.
241-GRT. Event™ Grass Growth Regulator. Registration Application for a Terrestrial
Non-crop Use Pattern. Pages 3-7 removed, draft label. Tox review 007121.
Document (PDF) (901 KB PDF).
July 07, 1989. Review. 4 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg. # 241-286. Arsenal. Expedite Review of Protocol for Aquatic Field Dissipation Study.
Review Protocol for Field Dissipation Study.
Document (PDF) (146 KB PDF).
July 11, 1989. Review. 13 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
EPA Reg. No. 241-286, 241-299 Review studies submitted in support of registration
MRID 41002301, 41023201. Pages 10-13 removed, registrant data.
Document (PDF) (494 KB PDF).
September 28, 1989. Memorandum. 3 Page(s).
Pamela Hurley. Toxicology Branch.
Event Herbicide. Comments on Company Response to Toxicology Branch Review of Registration
Application for a Terrestrial Non-crop Use Pattern. Tox Review 007506. Manufacturing process
information on page 1 & inert ingredient information on page 2 deleted.
Document (PDF) (166 KB PDF).
November 22, 1989. Memorandum. 54 Page(s).
Irving Mauer. Toxicology Branch I.
Imazapyr (Arsenal) - Mutagenicity Data Submitted under Accession No. 260,000;
EPA ID No. 241-273. Pages 10-24, 29-32, 37-41, 47-54 removed, registration data.
Tox review 007626.
Document (PDF) (1044 KB PDF).
December 27, 1989. Review. 7 Page(s).
Charles Lewis. Ecological Effects Branch.
File or Reg. No.: 100-617. Arsenal Herbicide. Registrant Response to Previous
EEB Review Plus Submission of Phytotoxicity Data to Support Forestry Use.
MRID 408118-02, 01.
Document (PDF) (108 KB PDF).
September 17, 1990. Memorandum. 6 Page(s).
Lucy Markarian. Registration Support Branch.
EPA Reg. No. 241-286 Arsenal Herbicide Technical (Imazapyr). Tox review 008837.
Document (PDF) (376 KB PDF).
June 24, 1991. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch I.
Arsenal (Imazapyr) - PP#8H5547 and PP#8H5548 Response to Deferral from DEB
Regarding Exemption from Tolerance for Arsenal.
Document (PDF) (116 KB PDF).
July 02, 1991. Memorandum. 81 Page(s).
William Dykstra. Toxicology Branch I.
Arsenal (Imazapyr) FAP#8H5547/8H5548 - Imazapyr in/on Palm Oil and Refined Sugar
- Submission of Chronic Toxicity Studies: A 2-Generation Rat Reproduction Study...
MRID 410395-01, -02, -03, -04, -05. Tox review 008426.
Document (PDF) (3705 KB PDF).
September 05, 1991. Memorandum. 1 Page(s).
Doug Urban. Ecological Effects Branch.
Arsenal Herbicide; Request for Approval of Nonfood Aquatic Uses.
Document (PDF) (43 KB PDF).
October 02, 1991. Memorandum. 135 Page(s).
Esther Rinde. Carcinogenicity Peer Review, HED.
Carcinogenicity Peer Review Meeting on IMAZAPYR. Tox review 008729.
Pages 21-29, 74-78, 82-87, 107-122 not included, registrant data.
Document (PDF) (1339 KB PDF).
December 05, 1991. DER. 10 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Growth and Reproduction of Aquatic Plants.
Species Tested: Navicula pelliculosa.
Pages 6-8 removed, registrant data. MRID 40811802.
Document (PDF) (281 KB PDF).
December 05, 1991. DER. 10 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Growth and Reproduction of Aquatic Plants.
Species Tested: Selenastrum capricornutum.
Pages 6-8 removed, registrant data. MRID 40811802.
Document (PDF) (315 KB PDF).
December 05, 1991. DER. 11 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Growth and Reproduction of Aquatic Plants.
Species Tested: Anabaena flos-aquae.
Pages 9-11 removed, registrant data. MRID 40811802.
Document (PDF) (315 KB PDF).
December 05, 1991. DER. 11 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Growth and Reproduction of Aquatic Plants.
Species Tested: Skeletonema costatum.
Pages 6-8 removed, registrant data. MRID 40811802.
Document (PDF) (336 KB PDF).
December 05, 1991. DER. 13 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Growth and Reproduction of Aquatic Plants.
Species Tested: Lemna gibba.
Pages 6-9 removed, registrant data. MRID 40811802.
Document (PDF) (352 KB PDF).
December 05, 1991. DER. 16 Page(s).
Prapimpan Kosawalt. KBN Engineering for EFED.
STUDY TYPE: Non-target plants: Germination- Tier I and II Species Tested:
Cucumber, Pea, Sunflower, Soybean, Sugarbeet, Tomato, Oat, Onion, Corn, and Wheat.
MRID 40811801.
Document (PDF) (282 KB PDF).
December 05, 1991. DER. 8 Page(s).
Robin Hart. KBN Engineering for EFED.
STUDY TYPE: Non-target plants: Seedling Emergence Tier I and II. Species Tested:
Cucumber, Pea, Soybean, Sunflower, Sugarbeet, Tomato, Oat, Onion, Corn and Wheat.
MRID 40811801.
Document (PDF) (367 KB PDF).
March 26, 1992. Memorandum. 9 Page(s).
Douglas Urban. Ecological Effects Branch.
Registrant Request to waive Tier III Terrestrial Plant Growth Test Requirement for
Arsenal Herbicide Concentrate (isopropanolamine salt of imazapyr). DP Barcode D153348.
To support the waiver, American Cyanamid has provided... reports on [spray] drift.
Document (PDF) (625 KB PDF).
March 26, 1992. Memorandum. 9 Page(s).
Douglas Urban. Ecological Effects Branch.
Registrant Request to Waive Tier III Terrestrial Plant Growth Test Requirement for
Arsenal Herbicide Concentrate (Isopropylamine salt of Imazapyr). DP Barcode D153348.
Document (PDF) (2000 KB PDF).
May 26, 1992. DER. 26 Pages.
Brian Montague. Ecological Effects Branch.
28-Day Early Life Stage Test with rainbow trout, Oncorhyncus mykiss.
MRID 413158-04.
Document (PDF) (866 KB PDF).
June 02, 1992. DER. 12 Pages.
Brian Montague. Ecological Effects Branch.
Twenty One Day Flow through Study with Daphnia magna. MRID 413158-05.
Document (PDF) (428 KB PDF).
July 17, 1992. Memorandum. 9 Page(s).
William Dykstra. Toxicology Branch.
FIFRA 88 Phase 4 Toxicology Review; Imazapyr; Arsenal; ID #: 128829-000214;
Reregistration Action. "... identify all applicable data requirements...".
DP Barcode: D177506.
Document (PDF) (501 KB PDF).
September 22, 1992. Review. 6 Page(s).
Doug Urban. Ecological Effects Branch.
DP Barcode D169018 ID#: 000241-00299 Amended label. Proposed uses on the
supplemental label are aquatic use sites in and around wetland areas...
Document (PDF) (263 KB PDF).
May 25, 1993. Memorandum. 15 Page(s).
Patricia Ott. Environmental Fate & Ground Water Branch.
Imazapyr (List C) - Phase 4 Review. Review data in support of proposed new aquatic uses.
DP Barcode Nos.: D177575 D176494, D174258, D165024.
Document (PDF) (905 KB PDF).
June 25, 1993. DER. 20 Page(s).
William Dykstra. Toxicology Branch I.
82-1; 90-Day Rat Feeding Study with Imazapyr Technical. MRID No. 42774401.
Document (PDF) (790 KB PDF).
September 15, 1994. Memorandum. 11 Page(s).
William Dykstra. Toxicology Branch I.
Imazapyr (Arsenal) American Cyanamid's Response to Review of Chronic Rat
& Mouse Studies & Requests of HED Peer Review Committee; ID #: 000241-00273.
DP Barcode No.: D191606. MRID 42774401.
Document (PDF) (758 KB PDF).
October 14, 1994. Memorandum. 16 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
EUP for ARSENAL on Aquatic Sites DP D205457 American Cyanaamid Corporation proposes
an experimental use for the isopropanolamine salt of imazapyr...including use on
ditch banks and "where impounded water is present in and around noncrop areas.".
Document (PDF) (528 KB PDF).
April 23, 1996. Memorandum. 3 Page(s).
Carol Glasgow. Registration Support Branch, RD.
EPA File Symbol/ EPA Reg. No: 241-GTT/FOR USE IN IMI-CORN™ ONLY; AC 513,996.
Eye irritation. DP Barcodes: D221657, D222036 and D224393.
MRID 43861513.
Document (PDF) (170 KB PDF).
June 24, 1996. Memorandum. 4 Page(s).
Carol Glasgow. Registration Support Branch, RD.
EPA File Symbol/ EPA Reg. No: 241-GTT/FOR USE IN IMI-CORN™ ONLY; AC 513,996
Resubmission. Acclimation period for eye irritation study. DP Barcode: D227235.
MRID 43861513.
Document (PDF) (204 KB PDF).
June 26, 1996. Memorandum. 41 Page(s).
Nancy Dodd. Chemistry Branch.
PP#6F04641 - Imazapyr on Field Corn. Review of Analytical Methods and Residue Data.
First Food Use Review. MRIDs 43861502; 43861503; 43861504; 43861505; 43861506;
43861516; 43861517; 43861518.
Document (PDF) (1877 KB PDF).
March 18, 1997. Memorandum. 2 Page(s).
Laura Parsons. Environmental Fate & Ground Water Branch.
EFED's Review of a new chemical registration of Lightning.
Document (PDF) (149 KB PDF).
March 18, 1997. Memorandum. 4 Page(s).
Laura Parsons. Environmental Fate & Ground Water Branch.
New chemical registration: Lightning. DP Barcode # : D233915.
Document (PDF) (294 KB PDF).
April 05, 1999. Memorandum. 5 Page(s).
Byron Backus. Technical Review Branch RD.
Subject: EPA Reg. No. 241-286: Arsenal Technical Herbicide. "Third acute oral study.
Can 'Harmful if swallowed' be removed from the label?". DP Barcode: D252516.
MRID 41551002, 44735301.
Document (PDF) (240 KB PDF).
March 10, 2003. DER. 15 Pages.
Stephen Carey. EPA.
Data Evaluation Report on the Chronic Toxicity of CL 243997 to the Early Life Stage
of Fathead Minnow. DP Barcode: D275562. MRID No. 45119711.
Document (PDF) (484 KB PDF).
March 10, 2003. DER. 31 Pages.
Stephen Carey. EFED, OPP.
FISH LIFE-CYCLE TOXICITY TEST. §72-5. Toxicity of AC 243997 (Imazapyr) Technical
During the Full Life-Cycle of the Fathead Minnow (Pimephales promelas) Under
Flow-Through Test Conditions. MRID No.: 45119712. DP Barcode: D275562.
Document (PDF) (1188 KB PDF).
March 12, 2003. DER. 12 Pages.
Stephen Carey. EPA.
Data Evaluation Report on the Acute Toxicity of ARSENAL® Herbicide
(21.5 % Imazapyr) to Rainbow Trout Oncorhynchus mykiss). DP Barcode: D275562.
MRID No. 45119713.
Document (PDF) (396 KB PDF).
March 26, 2003. Memorandum. 7 Pages.
William H. Donovan. Reregistration Branch 3 (RRB3).
Imazapyr. Chronic Dietary Exposure Assessment for the Section 3 Registration
Action on Grasses and Aquatic Sites. DP Barcode: D288806.
Document (PDF) (215 KB PDF).
March 29, 2003. DER. 15 Page(s).
Stephen Carey. EPA.
Data Evaluation Report on the Reproductive Effects of AC 243997 on Avian
Species Anas platyrhychos. EPA DP Barcode D275562. EPA MRID No. 45119714b.
Document (PDF) (602 KB PDF).
March 29, 2003. DER. 39 Page(s).
Stephen Carey. EPA.
Data Evaluation Report on the Reproductive Effects of AC 243997 on Avian
Species Colinus virginianus. EPA DP Barcode D275562. EPA MRID No. 45119714a.
Document (PDF) (1340 KB PDF).
April 15, 2003. Memorandum. 22 Pages.
J. Troy Swackhammer. Registration Action Branch 1.
Occupational, Residential and Recreational Exposure Characterization/Risk
Assessment for Imazapyr for Use at Aquatic Sites and on Pasture/Rangeland.
PC Code: 128821; DP Barcode: D289502.
Document (PDF) (1224 KB PDF).
July 17, 2003. Memorandum. 57 Pages.
Dana Vogel. Registration Action Branch 1.
PP#: PP 0F6166. Imazapyr in/on Rangeland and Aquatic Sites.
Health Effects Division (HED) Risk Assessment. PC Code: 128821.
DP Barcode: D291393. Case Nos: 293089. Submissions: S598694.
Document (PDF) (2824 KB PDF).
August 28, 2003. DER. 14 Page(s).
Alex Clem. Environmental Fate & Ground Water Branch.
164-2 and §165-5. Residues of CL 243997, CL 9140, and CL 119060 in aquatic field aquatic
dissipation and aquatic non-target organisms for Arsenal® herbicide applied to freshwater ponds.
MRID No. 45119707.
Document (PDF) (908 KB PDF).
September 02, 2003. DER. 22 Page(s).
Stephen Carey. Environmental Risk Branch III.
Data Evaluation Record Seedling Emergence EC25 Test 123-1(A) (Tier II).
The Effect of ARSENAL on Non-Target Terrestrial Plants Tier II. DP Barcode: D275562
MRID: 40811801.
Document (PDF) (833 KB PDF).
December 08, 2006. DER. 12 Pages.
Stephen Carey. Environmental Risk Branch III.
Data Evaluation Report on the Acute Toxicity of Arsenal® Herbicide (Salt of Imazapyr)
to Freshwater Invertebrates - Daphnia magna. DP Barcode D315644.
MRID No. 001537-79.
Document (PDF) (372 KB PDF).
December 08, 2006. DER. 13 Pages.
Stephen Carey. Environmental Risk Branch III.
Data Evaluation Report on the acute toxicity of Arsenal® Herbicide (Salt of Imazapyr)
to Rainbow Trout (Salmo gairdneri). DP Barcode D315644. MRID No. 001537-78.
Document (PDF) (432 KB PDF).
September 01, 2010. Memorandum. 5 Pages.
James Hetrick et. al. Environmental Risk Branch 3.
Ecological Risk Assessment and Drinking Water Exposure Assessment for Label
Amendment to Allow Use of... in aquatic environments. DP Barcode: D379032.
MRID 131629 thru -633, -635, 132030, 40811801, 41039505,41315801, -03, -04,-05,
43889102, 45119710, 45119714.
Document (PDF) (157 KB PDF).