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Index of Cleared Science Reviews for Avenge (PC Code 106401)

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Undated. DER. 3 Pages.
Whang Phang. Reregistration Branch 1.
Prenatal Developmental Study in Rats; OPPTS 870.3700 [83-3 (a)].
MRID No.: 41521203. This is a supplement to the original DER (Tox. Doc. No. 008798)
for the rat developmental toxicity study on difenzoquat (MRID 41521203).
Document (PDF) (250 KB PDF).

Undated. Review. 13 Page(s).
Ecological Effects Branch.
Avenge Wild Oat Herbicide: General Summary of Chemodynamic Properties
and Fate in the Environment.
Document (PDF) (878 KB PDF).

January 21, 1974. Review Summary. 5 Page(s).
J. W. Akerman. Ecological Effects Branch.
Environmental Safety Review Summary Temp Permit: 241-EXP-X. Petition: 4G1453.
Document (PDF) (220 KB PDF).

February 27, 1974. Memorandum. 12 Page(s).
Robert Coberly. Toxicology Branch.
Toxicity studies submitted to support temporary tolerances for Avenge in or on barley
straw, barley grain, in meat, fat and meat by-products of cattle, goats, hogs, horses,
and sheep. Tox review 001266. Inert ingredient info. deleted from pages 2 and 4-8.
Document (PDF) (1241 KB PDF).

March 11, 1974. Review. 8 Page(s).
Ronald Ney. Ecological Effects Branch.
Environmental Chemistry Evaluation of 1,2-dimethyl-3,5- diphenyl pyrazolium methyl
sulfate (Avenge) PP #4G1453.
Document (PDF) (454 KB PDF).

September 20, 1974. Review Summary. 2 Page(s).
J. W. Akerman. Ecological Effects Branch.
Environmental Safety Review Summary Registration: 241-EG.
Document (PDF) (67 KB PDF).

November 21, 1974. Memorandum. 2 Page(s).
Robert Jaeger. Toxicology Branch.
Toxicity studies submitted to support increase of temporary tolerances for Avenge.
Tox review 001267.
Document (PDF) (122 KB PDF).

December 30, 1974. Review Summary. 2 Page(s).
J. W. Akerman. Ecological Effects Branch.
Environmental Safety Review Summary.
Document (PDF) (111 KB PDF).

January 06, 1975. Review. 1 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
Environmental Chemistry Review for 1,2-dimethyl-3,5- diphenyl pyrazolium methyl
sulfate (Avenge Technical), Reg. No. 241-EGO. Pending registration action
information on page 1 is not included.
Document (PDF) (54 KB PDF).

January 21, 1975. Review. 23 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
Environmental Chemistry Review for Difenzoquat Methyl Sulphate (1,2-dimethyl-3,5-
diphenyl-1H-pyrazolium methyl sulphate) (Avenge). Permit No. 241-EXP, PP #5G1576,
American Cyanamid, Submitted 11/27/74.
Document (PDF) (1084 KB PDF).

January 21, 1975. Review. 5 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
Environmental Chemistry Review for Difenzoquat Methyl Sulphate (1,2-dimethyl-3,5-
diphenyl-1 H-pyrazolium methyl sulfate) (Avenge). Permit No. 241-EXP-46G, PP #4G1453
(Amendment to) American Cyanamid, 1/7/75.
Document (PDF) (218 KB PDF).

October 16, 1975. Review. 2 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
Environmental Chemistry Review of Experimental Permit Extension for Avenge.
Document (PDF) (78 KB PDF).

October 17, 1975. Review. 16 Page(s).
Scott Fredericks. Efficacy & Environmental Effects Branch.
241-EUP-64G Extension of Permit - Barley.
Document (PDF) (1193 KB PDF).

January 07, 1976. Review. 8 Page(s).
Scott Fredericks. Efficacy & Environmental Effects Branch.
241-ELN Petition 6F1703 (Esp. Section "C") Registration - Barley.
Document (PDF) (419 KB PDF).

January 19, 1976. Review. 16 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
241-ELN; 6F1703; Avenge Wild Oat Herbicide Registration.
Document (PDF) (842 KB PDF).

January 30, 1976. Memorandum. 11 Page(s).
Robert Coberly. Toxicology Branch.
Toxicity studies submitted to support establishment of tolerances for Avenge.
6F1703 also 4G1453, 5G1576. Inert ingredient information pages 2 and 6 not included.
Tox review 001268.
Document (PDF) (718 KB PDF).

September 28, 1976. Review. 2 Page(s).
Frederick Betz. Efficacy & Environmental Effects Branch.
241-ELN Resubmission for registration - Barley.
Document (PDF) (69 KB PDF).

August 14, 1978. Review. 1 Page(s).
John McLann. Animal Biology Lab/EPA.
Biological Report of Analysis Static jar test. Bluegill.
Document (PDF) (69 KB PDF).

October 25, 1978. Review. 1 Page(s).
John McLann. Animal Biology Lab/EPA.
Biological Report of Analysis Static jar test. Bluegill.
Document (PDF) (60 KB PDF).

December 15, 1980. Memorandum. 4 Page(s).
Sherell Sterling. Fungicide Herbicide Branch.
Avenge S Wild Oat Herbicide, EPA File Symbol: 241-EAE Tox review 000835.
Document (PDF) (265 KB PDF).

April 07, 1982. Review. 4 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 241-262 Avenge S Wild Oat Herbicide Dermal
Sensitization. Acc. No. 246992. Tox review 003146.
Document (PDF) (232 KB PDF).

January 07, 1988. Memorandum. 8 Page(s).
Dennis Szuhay. Science Support Branch.
Transmittal of Qualitative Use Assessment for Difenzoquat Methyl Sulfate (106401).
Document (PDF) (301 KB PDF).

May 10, 1988. DER. 11 Pages.
Krystyna K. Locke. Toxicology Branch.
Combined chronic toxicity/oncogenicity (rat). Tox. Chem. No.: 363A. Doc. No.: 006658.
MRID No.: :36710. Project No.: 8-0126. Title of Report: Chronic Oral Toxicity Study in
Rats with AC 84,777.
Document (PDF) (252 KB PDF).

May 10, 1988. DER. 11 Pages.
Krystyna K. Locke. Toxicology Branch.
Teratology - Rabbit. Doc. No.: 006658. TOX Chem No.: 363A. MRID No.: 144521.
Project No.: 8-0126. Title of Report: A Teratology Study with AC 84,777 in
Rabbits: Final Report.
Document (PDF) (246 KB PDF).

May 10, 1988. DER. 8 Pages.
Krystyna K. Locke. Toxicology Branch.
Reproduction (3-gen.) -- Rat. Tox. Chern. No.: 363A. Doc. No.: 006658. MRID No.: 37924.
Project No.: 8-0126. Title of Report: Final Report: Three-Generation
Reproduction Study in Rats.
Document (PDF) (262 KB PDF).

June 07, 1988. Memorandum. 105 Page(s).
Krystyna Locke. Toxicology Branch.
Difenzoquat, Toxicology Chapter of the Registration Standard Inert ingredient info
page 40 not included. Pages 89-93 and 99-101 removed, registration data. Tox review 006658.
Document (PDF) (3064 KB PDF).

July 12, 1988. Memorandum. 1 Page(s).
Allen Vaughan. Ecological Effects Branch.
Rergistration Standard for Difenzoquat - Nontarget Insect Studies.
Document (PDF) (40 KB PDF).

March 07, 1990. Memorandum. 7 Page(s).
Olga Odiott. Registration Support Branch.
EPA Reg. No. 241-239 Avenge Acute oral and primary eye irritation studies.
MRID No. 413005-01, -02. Pages 5-7 removed, draft label. Tox review 008769.
Document (PDF) (224 KB PDF).

October 01, 1990. Review. 6 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Review Adsorption/Desorption Study. MRID 414513-02
Document (PDF) (310 KB PDF).

November 12, 1991. Memorandum. 38 Page(s).
Krystyna Locke. Toxicology Branch.
Technical Difenzoquat (Avenge): Evaluation of a Teratology Study with Rats.
Pages 19-37 removed, registration data. MRID 41521203. Tox review 008798.
Document (PDF) (302 KB PDF).

April 20, 1992. Review. 69 Page(s).
Krystyna K. Locke. Toxicology Branch.
Difenzoquat (Avenge, AC 84,777): Evaluation of the Following Studies: Acute Oral,
Dermal & Inhalation: Dermal Sensitization, 21-Day Dermal & Three Mutagenicity
Studies. MRID 413254-06 thru 11,414153-03,04. Pgs. 37,50-55,66-74,82-85 removed, RD.
TXR 009451.
Document (PDF) (2379 KB PDF).

September 07, 1993. EFGWB One-Liner. 6 Page(s).
Environmental Fate and Ground Water Branch..
Pesticide Environmental Fate One Line Summary Difenzoquat.
Document (PDF) (299 KB PDF).

November 29, 1993. Review. 14 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Review uses of difenzoquat and indicate status of data requirements, prepare EEB
Science Chapter for Reregistration Eligibility Document.
Document (PDF) (693 KB PDF).

December 06, 1993. Review. 91 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
List A RED: Review environmental fate data MRID 413254-03, -04, -05, 419037-01,
-02, 417034-01. Pages 20-26, 30-37, 41-45, 50-54, 59-64, 69-81 and 86-88 removed,
registrant data.
Document (PDF) (2594 KB PDF).

January 19, 1994. Memorandum. 48 Pages.
Krystyna K. Locke. Toxicology Branch I.
Difenzoquat Methyl Sulfate (Technical AC 84,777): 83-1 Chronic Feeding study in the
Nonrodent and 83-2 carcinogenicity study in Mice. DP Barcode No.: D193941.
Submission No.: S445822. Tox. Chem. No.: 363 A. MRID Nos.: 42800401, 42800402.
Document (PDF) (1317 KB PDF).

February 02, 1994. Memorandum. 78 Page(s).
Krystyna Locke. Toxicology Branch I.
Difenzoquat Methyl Sulfate (Technical AC 84, 777): 83-1 Chronic Feeding Study in
the Nonrodent and 83-2 Carcinogenicity Study in Mice. MRID No.: 428004-01, -02.
Pages 26-31, 65-67 removed, RD. Tox review 010758.
Document (PDF) (3562 KB PDF).

April 05, 1994. Memorandum. 17 Page(s).
Sharlene Matten. Science Analysis & Coordination Staff.
Transmittal of EFED Cover Memorandum for the Reregistration Eligibility Document
for Difenzoquat (List A, Case #0223).
Document (PDF) (1120 KB PDF).

April 07, 1994. Memorandum. 5 Page(s).
Jeff Evans. Occupational & Residential Exposure Br.
Occupational and Residential Exposure Assessment and Recommendations for the
Difenzoquat Methyl Sulfate Reregistration Eligibility Document (RED).
Document (PDF) (304 KB PDF).

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