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Index of Cleared Science Reviews for Acephate (Pc Code 103301)
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Undated. Review. 62 Page(s).
Krystyna Locke. Toxicology Branch.
Topical Discussions - Acephate; (O,S-Dimethyl Acetylphos phoramidothioate).
Tox Review No. 003122.
Document (PDF) (2,767 KB PDF).
Undated. Study. 3 Page(s).
Chevron Chemical Company.
S-416: Acute Inhalation Toxicity of Orthene 75S. MRID No. 00014683.
Document (PDF) (1,823 KB PDF).
April 10, 1975. Letter. 2 Page(s).
Charles Smith. Registration Division.
Pesticide Petition No. 5G1604 & Food Additive Petition No. 5H5081. Temporary
Permit No. 239-EXP-71G. Inert ingredient information on page 1 is not included.
Document (PDF) (1,714 KB PDF).
April 17, 1975. Letter. 2 Page(s).
J. N. Ospenson. Chevron Chemical Company.
PP No. 5G1604 and FAP 5H5081. Temporary Permit No. 239-EXP-71G. Orthene 75S
Soluble Powder - Grapes. Inert ingredient information on page 2 is not included.
Document (PDF) (388 KB PDF).
June 13, 1975. Letter. 1 Page(s).
J. N. Ospenson. Chevron Chemical Company.
PP No. 5G1604 and FAP 5H5081. Temporary Permit No. 239-EXP-71G.
Orthene 75S Soluble Powder - Grapes.
Document (PDF) (187 KB PDF).
July 22, 1975. Letter. 1 Page(s).
Charles Smith. Registration Division.
Orthene 75S (Grapes). EPA Temporary Permit No. 239-EXP-71G.
Pesticide Petition No. 5G1604 and Food Additive Petition No. 5H5081.
Document (PDF) (133 KB PDF).
August 13, 1975. Letter. 1 Page(s).
J. N. Ospenson. Chevron Chemical Company.
Orthene 75S (Grapes). EPA Temporary Permit 239-EXP-71G. PP 5G1604 and FAP 5H5081.
Document (PDF) (75 KB PDF).
September 08, 1975. Letter. 1 Page(s).
Charles Smith. Registration Division.
Orthene 75S Soluble Powder (Grapes). EPA Temporary Permit No. 239-EXP-71G
Extension. Pesticide Petition No. 5G1604 and Food Additive Petition No. 5H5081.
Document (PDF) (160 KB PDF).
February 17, 1976. Memorandum. 1 Page(s).
D. Stubbs. Special Registration Section.
Labeling & Petition Review. Product Name: Orthene 75S. File Symbol: 239-EUP.
Petition No: 5G1604 & 5H5081.
Document (PDF) (128 KB PDF).
February 27, 1976. Memorandum. 1 Page(s).
David Ritter. Toxicology Branch.
PP #5G1604/FAP #5H5081. Proposal for Temporary Tolerances of Orthene in or on:
Grapes - 5 ppm. . . ; Raisins - 12 ppm. . . ; Raisin Wastes - 6 ppm. . . ; Grape Pomace
(Wet or Dry) - 10 ppm. . . ; Temporary Permit, Orthene 75S Soluble Powder, #239-EXP-71G.
Document (PDF) (177 K PDF).
May 26, 1976. Letter. 1 Page(s).
J. N. Ospenson. Chevron Chemical Company.
PP 5G1604 and FAP 5H5081. Orthene Insecticide (Acephate). Amendment of Section F.
Document (PDF) (184 KB PDF).
June 08, 1976. Letter. 2 Page(s).
Charles Smith. Registration Division.
EPA Experimental Use Permit No. 239-EUP-71. Orthene 75S (Grapes). Effective Dates:
July 6, 1976 to July 6, 1977. Quantity Authorized: 7,500 Pounds of Active Ingredient.
Document (PDF) (291 KB PDF).
June 10, 1976. Memorandum. 1 Page(s).
David Ritter. Toxicology Branch.
PP #5G1604/5H5081 - Orthene in Grapes, Raisins, Waste and Grape Pomace;
Amendment of 5/26/76.
Document (PDF) (78 KB PDF).
July 06, 1976. Letter. 2 Page(s).
John Ritch. Registration Division.
Pesticide Petition No. 5G1604. Food Additive Petition No. 5H5081.
Document (PDF) (300 K PDF)
October 17, 1980. Memorandum. 2 Page(s).
Richard Loranger. Residue Chemistry Branch.
EPA Reg. No. 239-2418 Acephate (ORTHENE) on lettuce. PP# 3F1375.
MRID 00015293.
Document (PDF) (361 KB PDF).
February 19, 1982. Profile. 25 Page(s).
R. Balcomb. Ecological Effects Branch.
ECOLOGICAL EFFECTS PROFILE.
Document (PDF) (251 KB PDF).
December 15, 1982. Memorandum. 3 Page(s).
William Schneider. Toxicology Branch.
Mutagenicity Test Requirements for Acephate.
Document (PDF) (103 KB PDF).
March 18, 1983. Memorandum. 51 Page(s).
Krystyna Locke. Toxicology Branch I.
Orthene Technical (RE-12420): Lifetime Oral Carcinogenicity Study in Mice.
No. 415-006; 2/24/82. Accn. No. 247717-247719. Tox Review 002602.
Document (PDF) (2,537 KB PDF).
April 27, 1983. Review. 7 Page(s).
Krystyna Locke. Toxicology Branch.
Section 18 Exemption for the Use of Acephate on Grapes in Arizona.
Document (PDF) (549 KB PDF).
April 28, 1983. Memorandum. 4 Page(s).
Edward Zager. Residue Chemistry Branch.
83-AZ-06. Proposed Section 18 Exemption for the Use of Acephate on Grapes in Arizona.
Document (PDF) (194 KB PDF).
February 05, 1984. Memorandum. 2 Page(s).
Krystyna Locke. Toxicology Branch II.
Addendum to Dominant Lethal Study of Acephate Technical (SX-1102). SOCAL
Project No. 1718: Diet Analyses. MRID No. 00119081. Tox Review No. 003615.
Document (PDF) (108 KB PDF).
April 17, 1984. Memorandum. 27 Page(s).
William Schneider. Toxicology Branch.
Review of Mutagenicity Studies on Acephate. Accn Nos. 251894 & 251895.
Tox Review 003756.
Document (PDF) (1,249 KB PDF).
May 14, 1985. Memorandum. 7 Page(s).
W. T. Chin. Residue Chemistry Branch.
PP #4E3091, (RCB #836) (Acc. #073430) Acephate in or on Blueberries.
Comments on the Amendment of 3/28/85.
Document (PDF) (295 KB PDF).
May 16, 1985. Memorandum. 7 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #4E3106 [RCB #961]. Acephate on Sugarcane Grown in Puerto Rico Only.
Evaluation of Amendment Dated April 19, 1985 (No Accession Number).
Document (PDF) (379 KB PDF).
June 27, 1985. Memorandum. 5 Page(s).
W. T. Chin. Residue Chemistry Branch.
PP #4F3101 (RCB #1071). Acephate in or on Leaf Lettuce. Amendment of 4/17/85.
Document (PDF) (324 KB PDF).
July 02, 1985. Memorandum. 4 Page(s).
W. T. Chin. Residue Chemistry Branch.
PP #4E3091, (RCB #1148) (Acc. #073430) Acephate in or on Blueberries.
Amendment of 6/3/85.
Document (PDF) (182 KB PDF).
August 29, 1985. Memorandum. 7 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #4E3043 [RCB #1247]. Acephate on Almonds. Evaluation of Amendment Dated June 24, 1985.
Document (PDF) (369 KB PDF).
September 10, 1985. Memorandum. 3 Page(s).
William Anthony. Residue Chemistry Branch.
EPA #239-2418. Acephate: Amended Use for Non-Bell Type Peppers in Puerto Rico.
[RCB #1299] [Acc. #258786].
Document (PDF) (162 KB PDF).
November 29, 1985. Memorandum. 8 Page(s).
Linda Kutney. Residue Chemistry Branch.
PP #4E3029. Acephate on Avocados. Amendment of 7/16/85. RCB #1435. (No Accession Number).
Document (PDF) (415 KB PDF).
May 06, 1986. Memorandum. 3 Page(s).
Michael Metzger. Residue Chemistry Branch.
86-WV-02. Proposed Section 18 Exemption for Acephate (Orthene 75S,
EPA reg. No. 239-2418) on Apples. RCB #880.
Document (PDF) (316 KB PDF).
May 20, 1986. Memorandum. 5 Page(s).
William Hazel. Residue Chemistry Branch.
Chevron Chemical Company's Comments on the Draft Registration Standard for
Acephate Dated September 1985 (Record No. 171863; RCB No. 822).
Document (PDF) (288 KB PDF).
June 20, 1986. Memorandum. 5 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #4E3043 [RCB #949]. Acephate on Almonds - Evaluation of Amendment Dated May 1, 1986.
Document (PDF) (274 KB PDF).
June 23, 1986. Memorandum. 4 Page(s).
W. T. Chin. Residue Chemistry Branch.
PP #4E3029 (No Acc. Number). Acephate and Methamidophos in or on Avocados.
Amendment of 4/14/86 (RCB #942).
Document (PDF) (212 KB PDF).
April 15, 1987. Memorandum. 3 Page(s).
William Anthony. Residue Chemistry Branch.
ID #NM-870001 [RCB #2040] [Acc. #: None]. Acephate (Orthene 75S): 24(c) on
Cottonseed in New Mexico.
Document (PDF) (163 KB PDF).
June 25, 1987. Memorandum. 4 Page(s).
Michael Metzger. Residue Chemistry Branch.
LA-860003. 24(c) Special Local Needs Registration for Acephate (Orthene 75S,
EPA Reg. No. 239-2418) Hopper-Box Cottonseed Treatment. No Accession Number/
No MRID Number. RCB #2255.
Document (PDF) (247 KB PDF).
July 08, 1987. Memorandum. 3 Page(s).
Francis Suhre. Residue Chemistry Branch.
SD-870003. Section 24(c) Registration of Orthene 75S Soluble Powder (Acephate)
to Control Grasshoppers on Range and Pasture Grass. MRID No. 197274; RCB No. 2463.
Document (PDF) (178 KB PDF).
July 13, 1987. Memorandum. 3 Page(s).
Francis Suhre. Residue Chemistry Branch.
SD-870002. Section 24(c) Registration of Orthene 75S Soluble Powder (Acephate)
to Control Grasshoppers on Field Borders, Fence Rows, Roadsides, Ditchbanks, and
Borrow Pits. No MRID or Accession No. , RCB No. 2462.
Document (PDF) (157 KB PDF).
December 16, 1987. Memorandum. 26 Page(s).
Krystyna Locke. Toxicology Branch.
Acephate Technical - Mouse Somatic Cell Mutation Assay and Range-Finding Study
Accession No. 40209101. Pages 10-15, 18-19 and page 24 removed, registrant data.
Tox review 006523.
Document (PDF) (939 KB PDF).
December 30, 1987. Memorandum. 2 Page(s).
Leung Cheng. Residue Chemistry Branch.
CA-870074. Section 24(c) Registration. Acephate on Greenhouse Lettuce Grown for Seed.
No MRID #. RCB #3119.
Document (PDF) (93 KB PDF).
February 18, 1988. Review. 8 Page(s).
Thomas Dixon. Exposure Assessment Branch.
Reg. No. : 239-2471 Review Droplet Size Spectrum and Drift Field Evaluation as
Registration Standard Followup.
Document (PDF) (427 KB PDF).
March 11, 1988. Memorandum. 2 Page(s).
William Anthony. Residue Chemistry Branch.
TN-870014 [RCB #3347][Acc. : None]. Acephate 24(c) on Tobacco (Burley) in the
State of Tennessee.
Document (PDF) (132 KB PDF).
March 23, 1988. Memorandum. 7 Page(s).
Krystyna Locke. Toxicology Branch.
Methylthioacetate - In Vitro Metabolism Study With rat and Rabbit MRID No. 403225-01.
Pages 6-7 removed, registrant data. Tox review 006632.
Document (PDF) (284 KB PDF).
April 27, 1988. Memorandum. 18 Page(s).
John Doherty. Toxicology Branch I.
EPA Registration No. 239-2471 - Acephate - Review of Rat 90-Day Feeding and
Single Dose Dermal Studies Designed to Assess for Anticholinesterase Activity
Acc. 405048-19, -20. Pages 17-18 removed, registrant data. Tox review 006680.
Document (PDF) (931 KB PDF).
May 05, 1988. Review. 9 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. # 215-345. Orthene PCO Spray Concentrate. Exposure Study for Registration Standard.
MRID 40504823.
Document (PDF) (595 KB PDF).
May 16, 1988. Review. 9 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. # 239-2471 Homeowner Exposure Study. MRID 40504827.
Document (PDF) (497 KB PDF).
May 23, 1988. Review. 30 Page(s).
Michael Firestone. Exposure Assessment Branch.
Mixer/loader and applicator exposure assessment for golf course use.
Pages 8-19 removed, registration data.
Document (PDF) (772 KB PDF).
May 26, 1988. Review. 7 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. # 239-2471. Green House Exposure Study. MRID 40504825.
Document (PDF) (512 KB PDF).
June 07, 1988. Review. 4 Page(s).
Frank Davido. Exposure Assessment Branch.
Reg. # 239-2471. Glove Permeability Study Protocol.
Document (PDF) (507 KB PDF).
June 14, 1988. Review. 14 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. # 239-2471 ORTHENE Tobacco Insect Spray Worker Exposure Assessment.
Document (PDF) (1,128 KB PDF).
June 15, 1988. Memorandum. 17 Page(s).
Krystyna Locke. Toxicology Branch.
Acute Dermal and Intravenous Studies with Methylthioacetate (MTA), a Manufacturing
Impurity in ORTHENE Technical (Acephate; EPA ID No. 239-2471).
MRID Nos 261971, 40322601. Tox review 006667 (and Tox review 006747).
Document (PDF) (868 KB PDF).
June 23, 1988. Review. 103 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Reg. # 239-2471 Addendum to Standard Pages 13-30, 34-54, 59-80 and 86-103
removed-registrant data.
Document (PDF) (1,138 KB PDF).
Attachment(s) Following:
May 20, 1988. Draft Report.
Dynamac Corporation. Exposure Assessment Branch.
Acephate Addendum Initial Draft Report Task 1: Review and Evaluation of
Individual Studies MRIDs 40504812 thru 40504815.
*End of Attachments*
June 23, 1988. Review. 13 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. # 223-409 Exposure Study.
Document (PDF) (858 KB PDF).
June 24, 1988. Memorandum. 13 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. : 239-2471. Acephate: Review of a multi- generation reproduction study
with rats conducted by the Argus Research Laboratories and dated April 3, 1987.
MRID 403234-01, 406057-01 Tox review 006759.
Document (PDF) (821 KB PDF).
June 24, 1988. Memorandum. 4 Page(s).
C. J. Nelson. Toxicology Branch.
ACEPHATE - Statistical Review of Cholinesterase Activity in Humans, Monkey
and Rat Page 4 removed-registrant data. Acc. No. 249639. Tox review 006960.
Document (PDF) (358 KB PDF).
June 27, 1988. Memorandum. 6 Page(s).
Francis Suhre. Residue Chemistry Branch.
Acephate; Residue Data in Support of a Dietary Exposure Assessment;
Record No. 223409; RCB No. 3944.
Document (PDF) (879 KB PDF).
Attachment(s) Following:
January 28, 1982. Report. 3 Page(s).
Dynamac Corporation.
Acephate Residue Chemistry. Task 4: Exposure Profile.
May 14, 1985. Memorandum. 5 Page(s).
William Hazel. Residue Chemistry Branch.
Feasibility of Reducing the Dietary Exposure to Acephate and its
Metabolite Methamidophos.
May 21, 1987. Memorandum. 3 Page(s).
Kyle Barbehenn. Science Integration Staff.
Acephate - Status of the ADI and the TMRC.
*End of Attachments*
July 28, 1988. Review. 12 Page(s).
Frank Davido. Exposure Assessment Branch.
Reg. # 239-2471 Submission of soil and foliar dislodgeable residue data in response
to data required under 40 CFR 158.390 and by the the Registration Standard for Acephate
and to fulfill Guidelines Requirement 132-1.MRIDs 405048-21, -22.
Document (PDF) (965 KB PDF).
August 04, 1988. Memorandum. 2 Page(s).
C. J. Nelson. Toxicology Branch.
ACEPHATE - Statistical Review of Cholinesterase Activity in Humans, Monkey and Rat.
Document (PDF) (76 KB PDF).
August 23, 1988. Memorandum. 6 Page(s).
Krystyna Locke. Toxicology Branch.
Request to Convene Toxicology Branch RfD/ADI Workgroup to Consider Re-evaluation
of the RfD/ADI for Acephate Pages 5-6 removed, registrant data.
MRID 00015160. Tox review 006861.
Document (PDF) (289 KB PDF).
October 31, 1988. Memorandum. 2 Page(s).
Arthur Schlosser. Non-Dietary Exposure Branch.
Assessment of Human Exposure to Acephate Resulting from Indoor Spot Treatment
Using Pressurized Spray Product.
Document (PDF) (108 KB PDF).
January 12, 1989. Memorandum. 26 Page(s).
Francis Suhre. Dietary Exposure Branch.
Acephate Dietary Exposure Assessment; MRID No. 405048-01 and 405048-03 thru 405048-09;
DEB No. 4419.
Document (PDF) (1,296 KB PDF).
January 24, 1989. Memorandum. 22 Page(s).
Krystyna Locke. Toxicology Branch I.
California Department of Food and Agriculture - EPA Toxicology Review for
Acephate (Tox. Chem. No. 2A) Chronic feeding/dog; IBT; No. C-8732; 12/28/72.
Manufacturing process info on page 22 is not included.
Document (PDF) (1,505 KB PDF).
Attachment(s) Following:
January 24, 1989. Memorandum.
Krystyna Locke. Toxicology Branch I.
California Department of Food and Agriculture - EPA Toxicology Review for
Acephate (Tox. Chem. No. 2A) Teratogenicity/rat; IBT; No. B-190; 9/17/71.
*End of Attachments*
January 30, 1989. Memorandum. 23 Page(s).
Susan Stanton. Science Analysis & Coordination Branch.
Acephate: TAS Dietary Exposure Analysis.
Document (PDF) (1,888 KB PDF).
February 28, 1989. Memorandum. 2 Page(s).
Arthur Schlosser. Non-Dietary Exposure Branch.
Request for a waiver of acephate handler exposure data for use on tobacco
(HED Project# 9-0922).
Document (PDF) (82 KB PDF).
June 19, 1989. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch I.
EPA Registration No. 239-2471 - Acephate: Acute Dermal Toxicity Study with
Methylthioacetate, a Contaminant of Technical Grade Acephate MRID 401459-02.
Tox review 007261.
Document (PDF) (321 KB PDF).
June 20, 1989. Memorandum. 66 Page(s).
John Doherty. Toxicology Branch I.
EPA Registration No. 239-2471 - Methylthioacetate (Contaminant of Acephate):
Review of Acute Oral and Dermal Toxicity Studies in Rats and Rabbits, Acute
Inhalation Toxicity in Rats, Subchronic Dermal Toxicity Studies in Rats (21 days) and ( cont. ).
Document (PDF) (3, 329 KB PDF).
Attachment(s) Following:
June 20, 1989. Memorandum.
John Doherty. Toxicology Branch I.
Rabbits (21- and 90-day studies); Studies to Assess Optic Nerve and/or Optic
Chiasma and Ocular Function; Review of Mutagenicity/Genetic Toxicity Studies
Tox review 007262(cont. ).
June 20, 1989. Memorandum.
John Doherty. Toxicology Branch I.
Tox review 007262 (continued) Quality control procedure information on page 3
not included Pages 53-54, 59-60 and 65-66 removed, registrant data.
MRID No. 405048-33, -34, -36, -35,-37,-38,-39,-40,-41,-42,43 Tox review 007262.
*End of Attachments*
June 22, 1989. EFGWB One Liner. 3 Page(s).
Environmental Fate and Ground Water Branch.
Pesticide Environmental Fate One Line Summary.
Document (PDF) (137 KB PDF).
December 06, 1989. Memorandum. 4 Page(s).
Stephen Funk. Dietary Exposure Branch.
Request for Experimental Use Permit for Field Testing of Orthene 75 (Acephate) on
Feral Honey Bees. I. D. No. 62549-EUP-R. Record No. 253271.
MRID No. 41250901. DEB No. 5893.
Document (PDF) (286 KB PDF).
December 27, 1989. Memorandum. 3 Page(s).
Jane Smith. Dietary Exposure Branch.
Acephate/Methamidophos. Separation of Tolerances in Acephate Registration Standard. DEB #5839.
Document (PDF) (150 KB PDF).
February 23, 1990. Memorandum. 6 Page(s).
Krystyna Locke. Toxicology Branch I.
EPA ID No. : 16-788. Tolerances for Acephate and Methamidophos Arising from Acephate.
Document (PDF) (347 KB PDF).
April 11, 1990. Memorandum. 3 Page(s).
Freshteh Toghrol. Dietary Exposure Branch.
AR-900002. 24(c) Acephate (Orthene 90S) for Use on Cotton to Control (Thrips and Aphids).
In-Furrow Application No MRID #, DEB #6544).
Document (PDF) (186 KB PDF).
May 08, 1990. Memorandum. 4 Page(s).
Freshteh Toghrol. Dietary Exposure Branch.
90-MD-05. Section 18 Specific Exemption for the Use of Acephate (Orthene 75S) on
Infested Feral Honey Bess with Varroa Mites, to Avoid Infesting the Domestic Bee
Colonies. EPA Reg. No. 59639-26. (No MRID #, DEB #6574).
Document (PDF) (201 KB PDF).
May 31, 1990. Memorandum. 4 Page(s).
Freshteh Toghrol. Dietary Exposure Branch.
Amended Registration for Orthene 90 S (Acephate) on Cotton In-Furrow Application.
EPA Reg. No. 59639-33. (No MRID #, DEB # 6350).
Document (PDF) (241 KB PDF).
July 16, 1990. Review. 5 Page(s).
Allen Vaughan. Ecological Effects Branch.
Reg. No. 239-2418 Proposed label amendment adding use on macadamia nuts.
Document (PDF) (316 KB PDF).
July 26, 1990. Memorandum. 16 Page(s).
Peg Perreault. Non-Dietary Exposure Branch.
Review of label protective clothing statements submitted in response to requirements
of the Reregistration Guidance Document for Acephate (HED Project #s 9-0849 and 48118).
Document (PDF) (976 KB PDF).
July 26, 1990. Memorandum. 20 Page(s).
Peg Perreault. Non-Dietary Exposure Branch.
Review of addenda to reentry studies submitted in response to the requirements of the
Reregistration Guidance Document for Acephate (HED Project # 9-1353).
Document (PDF) (1,431 KB PDF).
August 08, 1991. Final Report. 62 Page(s).
Dynamac Corporation. Residue Chemistry Branch.
ACEPHATE Shaugnessy No. 103301 Task 4: Residue Chemistry Reregistration Standard Update.
Document (PDF) (4,063 KB PDF).
August 30, 1991. Memorandum. 5 Page(s).
Krystyna Locke. Toxicology Branch I.
One-year dog feeding study with acephate technical: 6(a)(2) notice. Reg. No. 062499-00023.
Document (PDF) (214 KB PDF).
January 29, 1992. Memorandum. 28 Page(s).
Edward Zager. Chemistry Branch II.
Acephate Product and Residue Chemistry Reregistration Standard Updates;...
DP Barcode No. : D171638 Manufacturing process info on page 1 not included. Quality
control procedure info on pages 10, 11 not included. See 8/8/91 cleared acephate review...
Document (PDF) (1,556 KB PDF).
February 10, 1992. Review. 8 Page(s).
Henry Nelson. Envirnomental Fate & Ground Water Branch.
239-2471 Review additional spray drift information. MRID 410235-03, -04.
Document (PDF) (576 KB PDF).
April 20, 1992. Memorandum. 26 Page(s).
Krystyna Locke. Toxicology Branch I.
EPA ID No. : 062499-00023 Orthene Technical (Acephate): One-Year Dog Feeding
Study. EPA Guideline No. : 83-1 MRID No. 418120-01. Pages 17-26 removed,
registrant data. Tox review 009453.
Document (PDF) (860 KB PDF).
August 12, 1992. Memorandum. 3 Page(s).
W. T. Chin. Chemistry Branch.
ID #059639-TL: Registration for Orthene 15 Granular (Acephate) on Cotton In-Furrow
Application (CBTS #9490, D #175178).
Document (PDF) (210 KB PDF).
September 17, 1992. Memorandum. 4 Page(s).
Radames Lozada. Occupational & Residential Exposure Br.
Review of the reentry statement for a new registration of a granular Acephate product.
Document (PDF) (184 KB PDF).
December 28, 1992. Memorandum. 4 Page(s).
Robert Lascola. Chemistry Branch I.
ID# 059639-TL: Registration for Orthene 15G (Granular) (Acephate) on Cotton: I-Furrow
Application. CBTS# 10512. MRID# 424505-01.
Document (PDF) (257 KB PDF).
February 03, 1993. Review. 7 Page(s).
Richard Felthousen. Ecological Effects Branch.
review attached application for new registration of a granular acephate product for
in-furrow application to cotton.
Document (PDF) (419 KB PDF).
February 04, 1993. Review. 35 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Reg. No. 239-2471 Registrant response to upgrade residue monitoring study
previously reviewed by EEB for tobacco. MRID 405048-29.
Document (PDF) (2,386 KB PDF).
April 12, 1993. Review. 4 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Reg. No. 239-2471 Submission of terrestrial residue monitoring data for tobacco
and cotton in response to Registration Standard. MRID 408741-04, 408741-05.
Document (PDF) (247 KB PDF).
May 25, 1993. Review. 2 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
SRRD request for review of 72-hour DCI for this chemical (Case No. 0042).
Document (PDF) (121 KB PDF).
January 21, 1994. Memorandum. 2 Page(s).
Penelope Fenner-Crisp. Health Effects Division.
Acephate - Carcinogenicity in Animals.
Document (PDF) (163 KB PDF).
April 22, 1994. Memorandum. 2 Page(s).
Jeff Evans. Occupational & Residential Exposure Br.
Justification and cost estimates for the mixer/loader/applicator exposure monitoring
data required to support the reregistration of Acephate.
Document (PDF) (104 KB PDF).
May 12, 1994. Memorandum. 2 Page(s).
R. B. Perfetti. Chemistry Branch II.
Response to the Acephate Reregistration Standard: Memo of Meeting Held on 5/11/94
(no MRID, No CBRS No. , No Barcode No. ).
Document (PDF) (122 KB PDF).
December 22, 1994. Memorandum. 6 Page(s).
Paula Deschamp. Chemistry Branch II.
Reregistration of Acephate. 90-Day Response to Reregistra- tion DCI issued 3/1/94.
Document (PDF) (426 KB PDF).
October 31, 1995. Memorandum. 3 Page(s).
David Hrdy. Chemistry Branch II.
ACEPHATE. List A. Valent. CBRS Comments on Proposed Protocol for Pyrolysis
Study. Shaughnessy No. 103301; DP Barcode: D210615; CBRS No. 16078;
MRID No. : NO MRID...
Document (PDF) (220 KB PDF).
November 28, 1995. Memorandum. 2 Page(s).
Krystyna Locke. Toxicology Branch I.
Acephate Technical: Request For "Me-Too" Registration EPA ID No. 051036-EUA.
Document (PDF) (142 KB PDF).
January 22, 1997. Memorandum. 95 Pages.
Felecia A. Fort. Chemistry Branch II.
Acephate. List A Case No. 0042. Chemical No. 103301. Registant's Response to
Residue Chemistry Data Requirements. CBRS Nos. 17188, 17189, 17190, 17191,
17427, 17429. DP Barcodes D225794, D225795, D225796, D225786, D228007, D227969…
Document (PDF) (667 KB PDF).
Attachment(s) Following:
January 22, 1997. Memorandum. 95 Pages.
Felecia A. Fort. Chemistry Branch II.
(Continued)…MRID Nos. 43971602 thru -04 -06 thru -08 -10 -11, 44037801 thru -04.
*End of Attachments*
September 05, 1997. DER. 64 Pages.
Krystyna Locke. Toxicology Branch II.
Acephate: 3-Generation Reproduction Study in Rats Chevron Chemical Company.
1987. MRID No. 40323401. HED Doc. No. 006759. ACEPHATE 83-4 Three-Generation
Reproduction Study with Rats. MRID No. 40323401 (main study) and MRID No. 40605701.
Document (PDF) (838 KB PDF).
September 18, 1997. DER. 20 Pages.
Stephen Dapson. Toxicology Branch II.
Teratology - Developmental Toxicity Species: Rat Guidline: 83-3 a.
MRID No. 41081602.
Document (PDF) (721 KB PDF).
December 01, 1997. DER. 32 Pages.
Stephanie Syslo. Environmental Risk Branch II.
Data Evaluation Record. Study 1. CAS No. 30560-19-1. Study ID 43971601.
Pages 7-32, registrant data.
Document (PDF) (795 KB PDF).
December 03, 1997. Memorandum. 50 Page(s).
Krystyna Locke. Toxicology Branch II.
Orthene Technical (Acephate): Review of the Neurotoxicity Studies with Rats:
Acute Neurotoxicity Screening Battery (81-8), Two Acute Range-Finding Studies
& a Subchronic (13 Weeks) Study (82-7). MRID 44203301 thru -04. Tox review 012416.
Document (PDF) (3,270 KB PDF).
January 07, 1998. DER. 16 Page(s).
Stephanie Syslo. Environmental Risk Branch.
Photolysis studies of C14-acephate in water. 161-2. Photodegradation in water.
Pages 6-16 removed, registrant data. MRID 41081603.
Document (PDF) (420 KB PDF).
January 15, 1998. Memorandum. 10 Page(s).
George Ghali. Health Effects Division.
Acephate: Hazard Identification Committee Report. Tox review 012453.
Document (PDF) (683 KB PDF).
March 24, 1998. Memorandum. 23 Page(s).
Krystyna Locke. Toxicology Branch II.
Acephate - Updating the Oneliner by Inclusion of the Recently Prepared Executive
Summaries & New DERs. Tox Review No. 012544.
Document (PDF) (1,898 KB PDF).
April 07, 1998. Memorandum. 8 Pages.
Felecia A. Fort. Chemistry Branch II.
Acephate. Review of Storage Stability Data and Storage Intervals and Conditions.
Case No. 0042. Chemical No. 103301. DP BARCODE D235332.
MRID No. 44251701 and 44251702.
Document (PDF) (87 KB PDF).
August 11, 1998. One Liner. 23 Page(s).
Ecological Effects Branch.
Pesticide toxicity database report. EEB Oneliner Toxdata file (1991-97) (for Acephate).
Document (PDF) (1,964 KB PDF).
October 30, 1998. Memorandum. 80 Page(s).
Felecia Fort. Reregistration Branch 1.
ACEPATE HED Risk Assessment and Disciplinary Chapters for the Reregistration
Eligibility Decision (RED) Document.
Document (PDF) (10,150 KB PDF).
December 21, 1998. Memorandum. 2 Page(s).
Felicia Fort. Health Effects Division.
ACEPHATE. Revision of HED Risk Assessment for the Reregistration Eligibility
Decision (RED) Document to Include Registrant's Comments.
Document (PDF) (80 KB PDF).
December 23, 1998. Memorandum. 126 Page(s).
Stephanie Syslo. Environmental Risk Branch.
ACEPHATE: Revision of EFED Risk Assessment for the Reregistration Eligibility
Decision (RED) Document to Include Registrant's Comments.
Document (PDF) (8,872 KB PDF).
April 23, 1999. Memorandum. 24 Pages.
Hai-Ming Chou. Versar Inc. for EPA/OREB.
Review of Determination of Dislodgeable Foliar Residues in Succulent Beans
Treated with Acephate (MRID No. 447639-02).
Document (PDF) (567 KB PDF).
April 26, 1999. Memorandum. 21 Pages.
Hai-Ming Chou. Versar Inc. for EPA/OREB.
Review of Determination of Dislodgeable Foliar Residues in Tobacco Treated with
ORTHENE® 75 WSP (MRlD #447639-01).
Document (PDF) (522 KB PDF).
April 27, 1999. Memorandum. 25 Pages.
Hai-Ming Chou. Versar Inc. for EPA/OREB.
Review of Determination of Dislodgeable Foliar Residues in Cauliflower Treated with
Acephate (MRID No. 447639-04).
Document (PDF) (557 KB PDF).
April 29, 1999. Memorandum. 26 Pages.
Hai-Ming Chou. Versar Inc. for EPA/OREB.
Review of Determination of Dislodgeable Foliar Residues in Roses Treated with
ORTHENE® Turf, Tree & Ornamental Spray (OTTO) - MRID No. 447639-03.
Document (PDF) (702 KB PDF).
May 26, 1999. Memorandum. 14 Page(s).
Nancy McCarroll. Toxicology Branch I.
Acuphate: Review of 21-Day Dermal Toxicity in Rats - Main Study (
MRID No. 44541101) & 5-Day Pilot Study/Short & Intermediate -Term Dermal risk
Assessments. MRID No. 44541101. Tox Review 013396.
Document (PDF) (894 KB PDF).
August 09, 1999. Memorandum. 15 Pages.
Felecia Fort. Reregistration Branch 1.
Acephate. List A Case No. 0042. Chemical No. 103301. Magnitude of the Residue
in/on Cotton treated at Different Growth Stages. DP Barcodes D255614, D254635,
and D254638. MRID Nos. 44777001 -03 -04, 44791202.
Document (PDF) (113 KB PDF).
July 27, 2000. Memorandum. 24 Page(s).
Nancy McCarroll. Toxicology Branch I.
Acephate: Revised Review of 21-Da Dermal Toxicity in Rats (MRID No. 45134301)
& Revised Review of the Subchronic Inhalation (Nose Only) Toxicity Study in the Rat.
MRID Nos. 45134301 & 45134302. Tox Review No. 014258.
Document (PDF) (1,381 KB PDF).
April 12, 2002. Memorandum. 5 Page(s).
Susan Makris. Toxicology Branch.
D281187: Acephate (PC Code 103301) Comparative Cholinesterase Study Protocols. TXR 0050514.
Document (PDF) (209 KB PDF).
January 18, 2006. Memorandum. 6 Pages.
Mark Dow. Registration Action Branch I.
ACEPHATE - Review of "PRECISE"TM Granular Formulation Designed to Reduce Dustiness.
DP Code: 318423. MRID 46484301, 46484302.
Document (PDF) (190 KB PDF).
January 24, 2006. Memorandum. 30 Pages.
Nancy McCarroll. Toxicology Branch.
Acephate: Review of Developmental Neurotoxicity Study in Rats (MRlD 46151802).
TXR No. 0052318.
Document (PDF) (1635 KB PDF).
March 31, 2006. Memorandum. 33 Page(s).
Matthew Lloyd. Reregistration Branch HED.
HED's Review of Exposure of Workers During the Mixing and Loading of Orthene 97
- a Pelletized Formulation of Acephate. MRID 45597001. DP Barcode D281186.
Document (PDF) (1,332 KB PDF).
September 09, 2010. Memorandum. 132 Page(s).
John Liccione. RAB V.
Acephate and Methamidophos: Benchmark Dose Analysis of Acute Oral Studies
and derivation of a Point of Departure and Relative Potency Factor.
DP Barcode: D383706. TXR No.: 0055521. MRID No.: NA.
Document (PDF) (2,958 KB PDF).