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Index of Cleared Science Reviews for Abamectin (PC Code 122804)
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December 05, 1981. Data Eval. Rec. 2 Page(s).
Stephen Hopkins. Ecological Effects Branch.
The Effect of Avermectin B1 to Freshwater Alga Selanastrum capricornutum.
Accession No. 246358.
Document (PDF) (77 KB PDF).
December 15, 1981. Data Eval. Rec. 2 Page(s).
Stephen Hopkins. Ecological Effects Branch.
The Effect of Avermectin B1 to Duckweed. Accession No. 246358.
Document (PDF) (75 KB PDF).
December 15, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-00V50 to Rainbow Trout (Salmo gaidneri).
Accession No. 246358.
Document (PDF) (120 KB PDF).
December 16, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-35UO1 to Rainbow Trout (Salmo gairdneri).
Accession No. 246358. Inert ingredient information on page 1 is not included.
Document (PDF) (143 KB PDF).
December 17, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-OOV50 Technical to Bluegill (Lepomis macrochirus).
Accession No. 246358.
Document (PDF) (112 KB PDF).
December 17, 1981. Data Eval. Rec. 4 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-35UO1 to Bluegill (Lepomis macrochirus).
Accession No. 246358. Inert ingredient information on page 1 is not included.
Document (PDF) (146 KB PDF).
December 18, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-00V50 to the Water Flea (Daphnia magna).
Report #BW-81-6-938. Accession No. 246358.
Document (PDF) (124 KB PDF).
December 18, 1981. DER. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Technical Avermectin B1 (91.43% purity); 48-hour acute toxicity
to aquatic invertegrates; Test Species: Daphia Magna.
Document (PDF) (126 KB PDF).
December 21, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Toxicity of L-676, 863-35UO1 to the Water Flea (Daphnia Magna).
Accession No. 246358. Inert ingredient information on page 1 is not included.
Document (PDF) (146 KB PDF).
December 21, 1981. Data Eval. Rec. 4 Page(s).
Mary Gessner. Ecological Effects Branch.
Acute Oral LD50 of L-676, 836-OOV50 to Mallard Duck. Accession No. 246358.
Document (PDF) (192 KB PDF).
December 22, 1981. Data Eval. Rec. 4 Page(s).
Mary Gessner. Ecological Effects Branch.
Eight-Day Dietary LC50 of L-676, 863-OOV50 to Mallard Duck (Anas platyrhynchos).
Accession No. 246358.
Document (PDF) (179 KB PDF).
December 23, 1981. Data Eval. Rec. 3 Page(s).
Mary Gessner. Ecological Effects Branch.
Eight-Day Dietary LC50 of L-676, 863-OOV50 to Bobwhite Quail (Colinus virginianus).
Accession No. 246358.
Document (PDF) (162 KB PDF).
January 19, 1982. Review. 9 Page(s).
Mary Gessner. Ecological Effects Branch.
Exp. Permit No. 618-EUP-RN. MK-936 0.0055%, 0.0011%. Proposed EUP for Use on Fire Ants.
Inert ingredient information on pages 1, 2, and 6 is not included.
Document (PDF) (310 KB PDF).
February 05, 1982. Review. 8 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 618-EUP-RN. MK-936. Fire Ant Control.
Pages 5-8 are not included - draft label.
Document (PDF) (164 KB PDF).
March 10, 1982. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 618-EUP-RN. Avermectin B1. Use on Fire Ants.
Comments on Review.
Document (PDF) (90 KB PDF).
March 19, 1982. Memorandum. 18 Page(s).
William Dykstra. Toxicology Branch.
618-EUP-RN; MK-936; Avermectin B1 for control of fire ants.
Acc. #246894-895. Tox Review No. 001535.
Document (PDF) (910 KB PDF).
September 07, 1982. Review. 3 Page(s).
Samuel Creeger. Environmental Fate Branch.
File No. 618-EUP-10. Avermectin MK-936. Human Exposure.
Document (PDF) (97 KB PDF).
January 27, 1983. Memorandum. 3 Page(s).
Thomas Mao. Toxicology Branch.
Comments on the Draft Protocol of the Metabolism, Distribution & Excretion of
Tritium & Carbon-14 Labeled Avermectin Bla in Rats. EPA I.D. No. 618-EUP-10.
MRID No. 00131080.
Document (PDF) (147 KB PDF).
October 14, 1983. Review. 46 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 618-EUP-10. Avermectin B. (MK-936). Submission of Data (Avian)
to Support EUP and as Discussed in 4-28-83 Meeting with EEB Representatives.
Pages 5-15, 19-30, and 34-45 removed, registrant data.
Document (PDF) (463 KB PDF).
February 07, 1984. Data Eval. Rec. 2 Page(s).
Allen Vaughan. Ecological Effects Branch.
Bee Toxicity Dusting Test Summary. Accession No. 252115.
Document (PDF) (67 KB PDF).
February 07, 1984. Data Eval. Rec. 3 Page(s).
Allen Vaughan. Ecological Effects Branch.
Letter to Dr. John G. MacConnell and Attached Data. Accession No. 252115.
Honey Bee - Toxicity of Residues on Foliage.
Document (PDF) (137 KB PDF).
March 16, 1984. Data Eval. Rec. 14 Page(s).
John Bascietto. Ecological Effects Branch.
Acute Toxicity of MK-936 Technical to Embryo-Larvae of Eastern Oysters
(Crassostrea virginica). Accession No. 252115.
Pages 6-14 are not included - registrant data.
Document (PDF) (246 KB PDF).
March 19, 1984. Data Eval. Rec. 11 Page(s).
John Bascietto. Ecological Effects Branch.
Acute Toxicity of MK-936 Technical to Blue Crabs (Callinectes sapidus).
Accession No. 252115. Pages 5-11 are not included - registrant data.
Document (PDF) (178 KB PDF).
March 19, 1984. Data Eval. Rec. 3 Page(s).
John Bascietto. Ecological Effects Branch.
Acute Toxicity of MK-936 Technical to Pink Shrimp (Penaeus duorarum).
Accession No. 252115.
Document (PDF) (127 KB PDF).
March 20, 1984. Review. 8 Page(s).
John Bascietto. Ecological Effects Branch.
File No. 50658-EUP-R. Avid 0.15 EC (MK-936). Proposed EUP for Use on Citrus.
Document (PDF) (457 KB PDF).
March 28, 1984. Review. 10 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 122804. MK-936. Review Rotational Crop Study Protocol to Support
Use on Celery and Cotton. Pages 3-10 are not included - registrant data.
Document (PDF) (138 KB PDF).
March 28, 1984. Review. 38 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 50658-EUP-R. Avid. EUP on Citrus.
Pages 7-19, 21-24, 27-30, and 32-37 are not included - registrant data.
Document (PDF) (571 KB PDF).
April 28, 1984. Review. 4 Page(s).
Joseph Reinert. Exposure Assessment Branch.
File No. 50658-EUP-R. Avid. Exposure Assessment.
Document (PDF) (160 KB PDF).
June 22, 1984. Review. 7 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 618-OG. Affirm Fire Ant Bait.
Use on Non-Crop Land for Fire Ant Control, New Chemical Registration.
Inert ingredient information on pages 2, 5, and 7 is not included.
Document (PDF) (225 KB PDF).
June 29, 1984. Review. 10 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OG. Affirm Fire Ant Bait. Proposed Registration of Fire
Ant Bait for Agricultural Use (25# Bag) and Homeowner Use (1 lb Bag).
Uses: Pastures, Rangelands...Inert ingredient information on page 2 is not included.
Pages 8-10 are not included.
Document (PDF) (348 KB PDF).
July 11, 1984. Review. 5 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 84-FL-14. Avid 0.15 EC. Section 18 Use on Ornamentals.
Document (PDF) (718 KB PDF).
July 16, 1984. Review. 4 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 84-FL-14. Avermectin 0.15 EC.
Proposed Section 18 for Use on Ornamental Flowers and Foliage.
Document (PDF) (179 KB PDF).
September 10, 1984. Review. 3 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Applicator Exposure Assessment - Crop Destruct EUP on Citrus.
Document (PDF) (233 KB PDF).
Attachment(s) Following:
July 26, 1984. Memorandum. 1 Page(s).
David Severn. Exposure Assessment Branch.
Exposure Assessment for the Use of Avermectin on Ornamentals (Sec. 18).
*End of Attachments*
December 06, 1984. Memorandum. 10 Page(s).
William Dykstra. Toxicology Branch.
618-EUP-18, Avermectin B1; Rat & Rabbit Teratology Studies. Additional
Histopathology Data for Subchronic rat & dog studies. MRID No. 00131082.
Tox Review No. 004114.
Document (PDF) (485 KB PDF).
January 04, 1985. Review. 5 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
File 50658-EUP-R. Avermectin B1.
Worker Reentry Data in Support of EUP on Citrus.
Document (PDF) (251 KB PDF).
February 15, 1985. Review. 3 Page(s).
Joseph Reinert. Exposure Assessment Branch.
File No. 50658-EUP-R. MK-936. Exposure Assessment Protocol Review.
Document (PDF) (128 KB PDF).
March 07, 1985. Memorandum. 1 Page(s).
Daniel Rieder. Ecological Effects Branch.
Request for Environmental Fate Information on Avermectin, Reg. No. 618-OG.
Document (PDF) (51 KB PDF).
March 27, 1985. Review. 36 Page(s).
John Bascietto. Ecological Effects Branch.
File 50658-EUP-R. Avermectin B1. Request by Registrant for Determination of
Presence of Endangered Species in Areas of Proposed Treatment. Also Label Revisions.
Inert ingredient information on page 3 is not included.
Pages 17-36 deleted, registrant data.
Document (PDF) (836 KB PDF).
May 23, 1985. Review. 19 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 50658-EUP-R. Avid 0.15 EC. Review Revised Experimental Program.
Pages 4-19 are not included - registrant data.
Document (PDF) (125 KB PDF).
August 28, 1985. Review. 12 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File Nos. 618-OG and -OV. Affirm. New Chemical, Request for Product Registration
to Control Fire Ants. Inert ingredient information on pages 5-6 is not included.
Pages 8-12 are not included - registrant data.
Document (PDF) (386 KB PDF).
September 05, 1985. Review. 11 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File Nos. 618-OG and -OV. Affirm. Submission of Field Dissipation Study. Inert ingredient
information on page 3 is not included. Pages 5-8 are not included - registrant data.
Pages 9-11 are not included - draft label.
Document (PDF) (319 KB PDF).
September 10, 1985. Review. 8 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 50658-EUP-1. Avermectin. Amend Citrus EUP.
Pages 4-8 are not included - draft label.
Document (PDF) (149 KB PDF).
September 20, 1985. One-Liner. 2 Page(s).
Ecological Effects Branch.
Avermectin.
Document (PDF) (147 KB PDF).
September 26, 1985. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
50658-EUP-1; Avermectin; Avid 0.15 EC; EAB Deferral Regarding Estimation
of Reentry Exposure on Ornamentals. Caswell No. 063AB.
Document (PDF) (46 KB PDF).
October 28, 1985. Review. 12 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 50658-EUP-1. Abamectin. Proposed Revisions in EUP for Review by EEB.
Document (PDF) (482 KB PDF).
October 29, 1985. Review. 38 Page(s).
Daniel Rieder. Ecological Effects Branch.
File Nos. 618-OG; 618-OU. Affirm Fire Ant Bait and Insecticide - Avermectin.
Resubmission of Applications for Registration of Affirm (618-OG), (618-OU).
Data Reviews. Inert ingredient information on page 2 is not included.
Pages 14-30 are not included.
Document (PDF) (927 KB PDF).
October 30, 1985. Review. 4 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OL. Affirm. Proposed Full Registration of Technical
Product for Formulating Use.
Document (PDF) (137 KB PDF).
November 04, 1985. Memorandum. 2 Page(s).
Leung Cheng. Residue Chemistry Branch.
EPA File No. 618-OL. Abamectin. "Affirm Technical" Product Chemistry.
Accession Number 258707. RCB No. 1313.
Document (PDF) (114 KB PDF).
November 04, 1985. Review. 4 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File Nos. 618-OG and 618-OV. Affirm. Submission of Data in Response
to EAB Request of 9/05/85.
Document (PDF) (1283 KB PDF).
Attachment(s) Following:
September 20, 1985. Letter. 10 Page(s).
Louis Grosso. Merck Sharp & Dohme Research Labs.
Affirm Fire Ant Insecticide Bait (618-OG). Affirm Fire Ant Insecticide (618-OU).
Affirm Technical. Application for Registration - Submitted 7/12/85. (Fate of
Avermectin B1 in Soil and Plants, 1984).
*End of Attachments*
November 05, 1985. DER. 30 Page(s).
Daniel Rieder. Ecological Effects Branch.
Avermectin B1, Avermectin B1a Standard and 4 photodegradates; 48-hour LC50
with Daphnia magna. Pages 6-8 and 10-22 removed, registrant data. Acc. 258746.
Document (PDF) (553 KB PDF).
January 02, 1986. Review. 7 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 50658-EUP-E. Avermectin. EUP for Use on Cotton.
Pages 4-7 are not included - draft label.
Document (PDF) (142 KB PDF).
January 06, 1986. Review. 3 Page(s).
Daniel Rieder. Ecological Effects Branch.
File 618-OL. Abamectin MK-936. Submission of Avian Reproductive Study Protocol for Review.
Document (PDF) (115 KB PDF).
January 15, 1986. Review. 8 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg. No. 50658-EUP-1. Avermectin MK-936. Exposure Study.
Document (PDF) (378 KB PDF).
February 11, 1986. Review. 15 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 50658-EUP-E. Abamectin 0.15 EC. Proposed Experimental Use Permit
(EUP) for Use on Cotton.
Document (PDF) (703 KB PDF).
February 13, 1986. DER. 3 Page(s).
Daniel Rieder. Ecological Effects Branch.
Acute Toxicity of MK-936 Technical to Mysid Shrimp (Mysidopsis bahia).
Acc. No.: 259623.
Document (PDF) (96 KB PDF).
February 13, 1986. DER. 3 Page(s).
Daniel Rieder. Ecological Effects Branch.
Acute Toxicity of MK-936 to the Sheepshead Minnow; (Cyprinodon variegatus).
Acc. No.: 25962.
Document (PDF) (94 KB PDF).
February 13, 1986. DER. 4 Page(s).
Daniel Rieder. Ecological Effects Branch.
8 -hydroxy Avermectin B1a (Major soil metabolite of avermectin B1a.);
48-Hour LC50 with Daphnia magna.
Document (PDF) (134 KB PDF).
February 14, 1986. Review. 9 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OL. Affirm Technical. Submission of Further Data
to Support Registration.
Document (PDF) (267 KB PDF).
March 18, 1986. Review. 23 Page(s).
Samuel Creeger. Exposure Assessment Branch.
File No. 618-OA. Avid. New Application for Use in Flower Crops and Foliage
Plants for Control of Leafminers. Pages 5-19 are not included - registrant data.
Pages 20-23 are not included - draft label.
Document (PDF) (285 KB PDF).
April 10, 1986. Review. 29 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OA. Avid. Proposed Full Registration of New Chemical for Use on
Flower Crops and Foliage Plants. Pages 10-15 are not included - registrant data.
Pages 23-29 are not included - confidential statement of formula and draft labels.
Document (PDF) (695 KB PDF).
April 17, 1986. DER. 10 Page(s).
Daniel Rieder. Ecological Effects Branch.
Aquatic Invertebrate Life-Cycle; Species Tested: Daphnia Magna.
Pages 5-10 removed, registrant data. Acc. 259364.
Document (PDF) (203 KB PDF).
May 01, 1986. Memorandum. 6 Page(s).
Leung Cheng. Residue Chemistry Branch.
EPA File Symbol 618-OL Abamectin (Avermectin or AVM) AFFIRM Technical
Product Chemistry Accession No. 260785, RCB No. 388 Pages 5-6 removed,
manufacturing process, quality control procedures, inert ingredient info.
Document (PDF) (211 KB PDF).
June 06, 1986. Review. 4 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 618-96. Avid. Registration on Flower Crop.
Document (PDF) (133 KB PDF).
July 01, 1986. Memorandum. 2 Page(s).
Curt Lunchick. Exposure Assessment Branch.
Occupational Exposure Data Requirement for the Registration of Avermectin.
Document (PDF) (62 KB PDF).
September 26, 1986. Review. 2 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 618-EUP-10. Avermectin B1 (Affirm).
Registrant Response Concerning EEB Data Requirements.
Document (PDF) (108 KB PDF).
February 03, 1987. Memorandum. 3 Page(s).
Leung Cheng. Residue Chemistry Branch.
EPA File Symbol 618-OL Abamectin (Avermectin or AVM B1).
AFFIRM Technical Product Chemistry. Merck's Submission dated august 4, 1986.
No Accession Number. RCB No 1338. Acc 00145928.
Page 3 removed, manufacturing process info.
Document (PDF) (105 KB PDF).
February 19, 1987. Review. 12 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 50658-EUP-1. Abamectin. Proposed EUP for Citrus.
Document (PDF) (502 KB PDF).
March 10, 1987. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Abamectin (Avermectin) in/on Citrus; PP #7G3468/7H5518; 50658-EUP-1.
Document (PDF) (42 KB PDF).
March 10, 1987. Memorandum. 2 Page(s).
Stephen Saunders. Residue Chemistry Branch.
Amended TAS Analysis of Avermectin on Citrus. PP #7G3468/FAP #7H5518.
Document (PDF) (102 KB PDF).
March 27, 1987. Memorandum. 1 Page(s).
Robert Zendzian. Toxicology Branch.
Avermectin B1 Dermal Absorption.
Document (PDF) (39 KB PDF).
April 10, 1987. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Abamectin); PP #7G3468/7H5518; Avermectin in/on Citrus;
Risk Assessment for Harvesters Reentering Ornamental Field/Greenhouses
Treated with Avid 0.15 EC.
Document (PDF) (133 KB PDF).
Attachment(s) Following:
December 12, 1986. Memorandum. 15 Page(s).
William Dykstra. Toxicology Branch.
Plant Metabolite and Photodegradant of Abamectin;
Delta-8,9-Isomer of Abamectin Found in Citrus. Caswell No. 063AB.
Pages 2-15 are not included - registrant data.
*End of Attachments*
April 10, 1987. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Abamectin); Calculation of Margins of Safety for Use
on Citrus for Mixer/Loaders and Sprayers. Caswell No. 063AB.
Document (PDF) (577 KB PDF).
Attachment(s) Following:
January 15, 1987. Review. 8 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Exposure Study.
March 27, 1987. Memorandum. 24 Page(s).
Robert Zendzian. Toxicology Branch.
Avermectin B1, Dermal Absorption.
Pages 2-24 are not included - registrant data.
*End of Attachments*
April 16, 1987. Review. 3 Page(s).
Akiva Abramovitch. Exposure Assessment Branch.
Reg. No. 50658-EUP-1. Avid. EUP for Use on Citrus.
Document (PDF) (91 KB PDF).
April 20, 1987. Review. 10 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 50658-EUP-1. Avermectin. Revised Label and Section G in Compliance
with Endangered Species Concerns. Pages 4-10 are not included - registrant data.
Document (PDF) (200 KB PDF).
June 05, 1987. Review. 2 Page(s).
Therese Dougherty. Exposure Assessment Branch.
Reg. No. 50658-EUP-1. Avermectin. EUP for Use on Cotton.
Document (PDF) (80 KB PDF).
July 08, 1987. Review. 20 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. Nos. 618-EUP-12 and 50658-EUP-2. Avermectin. Amendment to EUPs.
Pages 7-20 are not included - registrant data.
Document (PDF) (566 KB PDF).
July 28, 1987. Review. 2 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. Nos. 50658-EUP-2 and 618-EUP-12.
Avermectin. Request Revisions to Cotton EUP.
Document (PDF) (68 KB PDF).
August 12, 1987. Letter. 43 Page(s).
W. F. Millar. California Dept. of Food & Agriculture.
Re: Abamectin Risk Characterization Document.
Inert ingredient information on pages 3, 5, 29, and 30 is not included.
Commercial/financial information on page 4 is not included.
Document (PDF) (2253 KB PDF).
September 14, 1987. Review. 81 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OT. Agrimec (Abamectin, Avermectin, MK-936).
Submission of Data to Support Proposed Registration of Cotton Use.
Pages 20-56, and 61-81 are not included - registrant data.
Document (PDF) (1028 KB PDF).
September 23, 1987. Review. 53 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OT. Agrimec 0.15 EC (Avermectin). Submission of Avian
Reproduction Study and Earthworm Toxicity Study to Support Cotton Use.
Pages 7-37, and 40-52 are not included - registrant data.
Document (PDF) (793 KB PDF).
October 19, 1987. Memorandum. 2 Page(s).
Curt Lunchick. Exposure Assessment Branch.
Qualitative Exposure Assessment for Avermectin Use on Cotton (No EAB Number).
Document (PDF) (85 KB PDF).
November 09, 1987. Memorandum. 5 Page(s).
William Dykstra. Toxicology Branch.
Avermectin - Results of Histological Analysis Eye Lesion in Rat Reproduction
Study (TT#82-9010). MRID No. 00164151. Tox Review No. 006447.
Document (PDF) (193 KB PDF).
November 24, 1987. Review. 5 Page(s).
Ecological Effects Branch.
Proposed Protocol - soil & plant residue test.
Document (PDF) (221 KB PDF).
Attachment(s) Following:
November 30, 1987. Memorandum.
Daniel Reider. Ecological Effects Branch.
Evaluation of Proposed Residue Study on Abamectin (Field Study Protocol Review).
November 30, 1987. Memorandum.
Daniel Reider. Ecological Effects Branch.
Evaluation of Proposed Residue Study on Abamectin.
*End of Attachments*
December 30, 1987. Review. 3 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OT. Agrimec (0.15 lb/gal EC).
Registrant Response Concerning Mysid Shrimp Life Cycle Studies.
Document (PDF) (104 KB PDF).
February 25, 1988. Review. 5 Page(s).
Allen Vaughan. Ecological Effects Branch.
Reg. No. 88-OR-06. Avermectin (Agrimec 0.15 EC).
Proposed Section 18 for Use on Pears in Oregon.
Document (PDF) (219 KB PDF).
March 08, 1988. Review. 10 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 88-FL-05. Agrimec 0.15 EC (Avermectin).
Proposed Section 18 for Use on Tomatoes in Florida.
Document (PDF) (479 KB PDF).
March 11, 1988. Memorandum. 7 Page(s).
Susan Stanton. Residue Chemistry Branch.
Avermectin - TAS Analysis of Proposed Section 18
Exemption for Use on Fresh Market Tomatoes (#88-FL-05).
Document (PDF) (322 KB PDF).
March 17, 1988. Review. 12 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OI. Agrimec 0.15 EC (Avermectin).
Proposed Registration of Use on Citrus.
Document (PDF) (598 KB PDF).
March 21, 1988. Memorandum. 8 Page(s).
William Dykstra. Toxicology Branch.
Avermectin - 88-FL-05 - Section 18 Request to Use Avermectin on Tomatoes for
"Fresh Market Only". Commercial/financial information on page 1 is not included.
Pages 5-8 are not included - draft label.
Document (PDF) (265 KB PDF).
March 28, 1988. Memorandum. 9 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - 88-OR-06 - Section 18 Request to Use
Avermectin on Pears in Oregon. Pages 6-9 are not included - draft label.
Document (PDF) (3372 KB PDF).
Attachment(s) Following:
April 23, 1987. Memorandum. 64 Page(s).
Willaim Dykstra. Toxicology Branch.
Abamectin (Avermectin) in/on Citrus - PP #7G3468/7H5518; 50658-EUP-1 -
Caswell No. 063AB... Inert ingredient info on pages 7-8 is not included.
Pages 60-64 removed, draft label. Accession Nos. 265563 through 265577 and 265584.
Tox review 005850.
*End of Attachments*
March 30, 1988. Review. 8 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 88-WA-10. Agrimec 0.15 EC (Avermectin).
Proposed Section 18 for Use on Pears in Washington.
Document (PDF) (376 KB PDF).
April 08, 1988. Summary. 33 Page(s).
John Bascietto. Ecological Effects Branch.
Chemical Profile - Avermectin (MK-936). Pages 7-19 are not included - registrant data.
Inert ingredient information on pages 25, 30, and 31 is not included.
Document (PDF) (854 KB PDF).
April 21, 1988. Review. 11 Page(s).
Frank Davido. Exposure Assessment Branch.
Reg./File # 50658-EUP-1 Review the attached foliar dislodgeable residue
data in support of the use of avermectin (Avid 0.15 EC) on citrus.
Document (PDF) (466 KB PDF).
April 25, 1988. Memorandum. 34 Page(s).
Martin Kovacs. Residue Chemistry Branch.
PP#8F3592/FAP#8H5550 - Avermectin B1 (Abamectin) on Citrus - Evaluation of Analytical Method
and Residue Data - Accession Nos. 404430-01 through 404430-10- RCB Nos. 3142 and 3143.
Document (PDF) (2186 KB PDF).
April 28, 1988. Memorandum. 2 Page(s).
V. F. Boyd. Residue Chemistry Branch.
Avermectin PP#8F3592 and PP#7F3500 - RCB Conference with Merck, 4/13/88,
Second Meeting Concerning Nature of Polar Degradates for Toxicological Testing.
Document (PDF) (92 KB PDF).
May 17, 1988. Review. 4 Page(s).
Richard Lee. Ecological Effects Branch.
Reg. No. 88-CA-20. Avid 0.15 EC (Avermectin). Proposed Sec. 18 for Use on Pears.
Document (PDF) (166 KB PDF).
May 19, 1988. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - EPA Experimental Use Permit No. 50658-
EUP-1. EAB Deferral Regarding Reentry in Citrus Crops. Caswell No. 063AB.
Project No. 8-0699.
Document (PDF) (566 KB PDF).
Attachment(s) Following:
April 21, 1988. Review. 11 Page(s).
Frank Davido. Exposure Assessment Branch.
Review the Attached Foliar Dislodgeable Residue Data in
Support of the Use of Avermectin (Avid 0.15 EC) on Citrus.
*End of Attachments*
May 24, 1988. Review. 3 Page(s).
Insecticide Rodenticide Branch.
EPA File Symbol 475-ETT. Black Flag Roach Control System II.
Acute Toxicity Data and Proposed Product Labeling.
Document (PDF) (132 KB PDF).
June 23, 1988. Review. 9 Page(s).
Paul Mastradone. Exposure Assessment Branch.
PP Nos. 8F3592, 8H5550. Avermectin. Registration for Use on Citrus.
Pages 4-8 are not included - registrant data.
Document (PDF) (227 KB PDF).
August 10, 1988. Review. 9 Page(s).
Frank Davido. Exposure Assessment Branch.
Reg./File # 618-02 Review the attached foliar dislodgeable residue data in support
of the use of avermectin (Avid 0.15 EC) on citrus: Addendum to previous submission.
Document (PDF) (475 KB PDF).
August 18, 1988. Review. 4 Page(s).
Paul Mastradone. Exposure Assessment Branch.
Reg. # 618-OT. Field dissipation and crop rotation data requirements.
Document (PDF) (198 KB PDF).
September 02, 1988. Memorandum. 5 Page(s).
Frank Boyd. Dietary Exposure Branch.
PP#8F3592/FAP#8H5550 - Abamectin (Avermectin B1) on Citrus - Evaluation of
"Method of Evaluation Report of June 14, 1988 on Meat and Milk Method" -
MRID Nos. 406368-01 and -02 - DEB Nos. 3929 and 3920.
Document (PDF) (192 KB PDF).
November 16, 1988. Memorandum. 19 Page(s).
Frank Boyd. Dietary Exposure Branch.
PP#8F3649 - Avermectin B1 (AVM b1) on Celery - Evaluation of Analytical Method,
Residue Data, and Metabolism - MRID Nos. 224705-223065; RCB Nos. 4094 and 4095.
Pages 8-9 removed, registrant data.
Document (PDF) (886 KB PDF).
December 01, 1988. Memorandum. 8 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - 89-FL-08 - Section 18 Request to Use
Avermectin on Celery in Florida. Pages 5-8 are not included - draft label.
Document (PDF) (210 KB PDF).
December 21, 1988. Memorandum. 6 Page(s).
Susan Stanton. Residue Chemistry Branch.
Avermectin - TAS Analysis of Proposed Section 18 Exemption for Use on Celery (#89-FL-08).
Document (PDF) (306 KB PDF).
January 01, 1989. Review. 1 Page(s).
George Ghali. Science Analysis & Coordination Branch.
Amendments to Existing RfD Values.
Document (PDF) (50 KB PDF).
January 17, 1989. Review. 18 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg. # 618-OI. Expedite review of field dissipation study to support use on cotton,
citrus, woody ornamentals, celery and tomatoes. Pages 8-16 removed, registrant data.
MRID 409271-01, -02.
Document (PDF) (373 KB PDF).
January 26, 1989. Review. 9 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-00. Agrimec 0.15 EC (Avermectin).
Proposed Registration of Use on Ornamental Plants.
Document (PDF) (444 KB PDF).
January 27, 1989. Review. 15 Page(s).
William Gill. Ecological Effects Branch.
File or Reg. No. 618-OI Proposed Registration for Use on Celery.
Document (PDF) (882 KB PDF).
February 13, 1989. Memorandum. 8 Page(s).
Frank Boyd. Dietary Exposure Branch.
PP#8F3592/FAP#8H5550 - Citrus Derived Polar Degradates of Avermectin B1a
Used for Teratology Testing - Characterization of the Degradates - Amendment
of November 8, 1988; MRID Nos. 409127-1 and 408833-1.
Document (PDF) (361 KB PDF).
February 14, 1989. Review. 4 Page(s).
Richard Lee. Ecological Effects Branch.
Reg. No. 89-CA-10. Avid 0.15 EC (Avermectin).
Proposed Sec. 18 for Use in Strawberries.
Document (PDF) (168 KB PDF).
February 17, 1989. Memorandum. 4 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - 89-CA-10 - Section 18 Request to Use
Avermectin on Strawberries in California.
Document (PDF) (197 KB PDF).
February 23, 1989. DER. 11 Page(s).
Kimberly Rhodes. Ecological Effects Branch.
Estuarine Organism 96-hour Flow-Through Toxicity Test. Species Tested:
Mysid Shrimp (Mysidopsis bahia). Pages 6-7 removed, registrant data.
Accession No. 408563-05.
Document (PDF) (556 KB PDF).
February 24, 1989. Memorandum. 7 Page(s).
Susan Stanton. Residue Chemistry Branch.
Avermectin - TAS Analysis of Proposed Section 18 Exemption
for Use on Strawberries (#89-CA-10).
Document (PDF) (345 KB PDF).
March 09, 1989. Review. 2 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg./File #: 618-OI Data requirements for use on celery.
Document (PDF) (69 KB PDF).
March 15, 1989. Memorandum. 15 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1 (Abamectin) - Additional Toxicology Studies with
Delta-8,9-Isomer and Polar Degradates - PP #8F3592 and 8H5550 (Citrus);
PP #7F3500 (Cotton). Tox Review 007080.
Inert ingredient and quality control procedure info on pages 3 and 7 removed.
Document (PDF) (748 KB PDF).
Attachment(s) Following:
September 02, 1987. Memorandum. 2 Page(s).
Willaim Dykstra. Toxicology Branch.
Avermectin - Meeting with Registrant (Merck). Tox Review 007080.
*End of Attachments*
March 15, 1989. Memorandum. 8 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1 (Abamectin) - PP #8F3592/8H5550/7F3500 - Mouse Teratology
Study with Citrus-Derived Polar Degradates of Abamectin. Tox Review 007081.
Page 8 is not included - registrant protocol.
Document (PDF) (856 KB PDF).
Attachment(s) Following:
September 02, 1987. Memorandum. 1 Page(s).
Willaim Dykstra. Toxicology Branch.
Avermectin - Meeting with Registrant (Merck). Tox Review 007081.
February 13, 1989. Memorandum. 8 Page(s).
Frank Boyd. Dietary Exposure Branch.
PP #8F3592/FAP #8H5550 - Citrus-Derived Polar Degradates of Avermectin
B1a Used for Teratology Testing - Characterization of the Degradates -
Amendment of November 8, 1988; MRID Nos. 409127-01 and 408833-01.
Tox Review 007081.
*End of Attachments*
March 15, 1989. Memorandum. 9 Page(s).
William Dykstra. Toxicology Branch.
Avermectin - Agrimec 0.15 EC - Avid 0.15 EC- EPA Registration No. 618-96 and
EPA File Symbol 618-OI -Submission of New Ocular Irritation Study in Rabbits.
Tox Review 007082. Commercial/financial info on pgs. 1, 3 not included.
Pgs 6-9 removed, draft Label.
Document (PDF) (199 KB PDF).
March 17, 1989. DER. 12 Page(s).
William Dykstra. Toxicology Branch.
One-Hundred & Five-Week Dietary Carcinogenicity & Toxicity Study in Rats.
MRID Nos. 400696-01, Vol. 1-11; 405178-01, Vol. 1 & 2; & 403755-11.
Tox Review No. 007093.
Document (PDF) (605 KB PDF).
March 22, 1989. Memorandum. 29 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1 (Also Called Abamectin) - PP #7F3500 (Avermectin B1 in/on Cotton)
- PP #7G3468, 7H5518 (Avermectin B1 in/on Citrus, Temporary Tolerances); and PP
#8F3592, 8H5550 (Avermectin B1 in/on Citrus, Permanent Tolerances)...
Tox Review 007093.
Document (PDF) (1554 KB PDF).
March 23, 1989. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
EPA File Symbol 618-OI - Avermectin B1 (Also Called Abamectin) - Deferral from
Exposure Assessment Branch Regarding Polar Degradates in Citrus and Cotton.
Document (PDF) (323 KB PDF).
Attachment(s) Following:
August 18, 1988. Review. 4 Page(s).
Paul Mastradone. Exposure Assessment Branch.
File No. 618-OI. Avermectin. Field Dissipation and Crop Rotation Data Requirements.
*End of Attachments*
March 28, 1989. Review. 3 Page(s).
James Goodyear. Ecological Effects Branch.
Reg. No. 89-FL-20.
Agri-Mek 0.15 EC, Avermectin. Section 18 for Use on Strawberries.
Document (PDF) (122 KB PDF).
March 31, 1989. Memorandum. 6 Page(s).
David Brassard. Biological Analysis Branch.
Biological Evaluation of Public Interest Documentation Submitted by Merck &
Dohme Research Laboratories in Support of Conditional Registration of Avermectin
B1 on Cotton and Citrus.
Document (PDF) (328 KB PDF).
April 05, 1989. Memorandum. 15 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1 (Also Called Abamectin) - Agrimec 0.15 EC - EPA File Symbol 618-
OI - PP #8F3592/8H5550 - Abamectin in/on Citrus - Registration and Tolerance
Request. Commercial/financial info on page 2 is not included.
Pages 12-15 deleted, draft label.
Document (PDF) (431 KB PDF).
April 06, 1989. Memorandum. 13 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1 (Also Called Abamectin) - Agrimec 0.15 EC - EPA File Symbol 618-
OI - PP #7F3500 - Abamectin in/on Cottonseed - Registration and Tolerance Request.
Commercial/financial info on page 2 is not included. Pages 10-13 deleted, draft label.
Document (PDF) (435 KB PDF).
Attachment(s) Following:
March 29, 1989. Memorandum. 1 Page(s).
Curt Lunchick. Science Analysis and Coordination Branch.
Exposure Assessment for Workers Exposed to Avermectin
B1 Applied to Cotton, Celery, and Tomatoes.
*End of Attachments*
April 06, 1989. Review. 5 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg./File #: 618-OI Review request to register product on tomatoes.
Document (PDF) (255 KB PDF).
April 11, 1989. Review. 54 Page(s).
Daniel Rieder. Ecological Effects Branch.
File No. 618-OI. Agrimec 0.15 EC (Avermectin). Submission of Laboratory
Toxicity Data and Registrant's Wild Mammalian and Aquatic Risk Assessment
for Cotton and Citrus. MRID 408563-03, -02.
Document (PDF) (4057 KB PDF).
April 14, 1989. DER. 5 Page(s).
Kimberly Rhodes. Ecological Effects Branch.
Estuarine Organism 96-hour Flow-Through Toxicity Test.
Species Tested: Mysid Shrimp (Mysidopsis bahia). Accession No. 408563-04.
Document (PDF) (365 KB PDF).
April 14, 1989. DER. 8 Page(s).
Kimberly Rhodes. Ecological Effects Branch.
28-Day Chronic Toxicity Test. Species Tested: Mysid Shrimp (Mysidopsis bahia).
Page 6 removed, registrant data. Accession No. 408563-01.
Document (PDF) (551 KB PDF).
April 26, 1989. Memorandum. 6 Page(s).
Robert Tomerlin. Tolerance Assessment System Staff.
Chronic and Acute Dietary Exposure Analyses for the Use of Avermectin on Cotton, 7E3500.
Document (PDF) (379 KB PDF).
May 17, 1989. Review. 4 Page(s).
Richard Lee. Ecological Effects Branch.
Reg. No. 89-ID-07. Avermectin. Proposed Sec. 18 for Use on Pears.
Document (PDF) (158 KB PDF).
May 31, 1989. Memorandum. 5 Page(s).
William Dykstra. Toxicology Branch.
Avermectin - Correction in Conclusion of Rabbit Teratology Study.
Tox Review 007227.
Document (PDF) (343 KB PDF).
Attachment(s) Following:
March 07, 1985. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
Avermectin B1; 618-EUP-10; PP #4F3065; 50658-EUP-R; 618-OG;
Historical Control Data for Rat and Rabbit Teratology Studies.
Caswell #063AB. Accession #073303. Tox Review 004335.
*End of Attachments*
June 21, 1989. Memorandum. 16 Page(s).
Frank Boyd. Dietary Exposure Branch.
PP#8F3592/FAP#8H5550 - Abamectin (Avermectin B1) on Citrus - Evaluation
of Petitioner Response (9/16/88) to the DEB Review of 4/25/88.
MRID No. 408315-01 and DEB Nos. 4457 and 4458.
Document (PDF) (1042 KB PDF).
June 29, 1989. Memorandum. 4 Page(s).
V. F. Boyd. Dietary Exposure Branch.
PP#8F3592/FAP#8H5550 - Avermectin B1 (Abamectin) on Citrus - Anticipated
Residues of Avermectin in Citrus Juice and Milk - Chronic Exposure.
Document (PDF) (150 KB PDF).
June 30, 1989. Efficacy Review. 1 Page(s).
Vern McFarland. Insecticide Rodenticide Branch.
EPA File No. 475-EII. Black Flag FAtal Attraction. Provide Additional Data
Required to Support Claims for Comprehensive Raoch Control for this Chemical
as Previously Requested in Connection w/ 475-ETT.
Document (PDF) (95 KB PDF).
July 07, 1989. Memorandum. 7 Page(s).
J. R. Tomerlin.
Note To: George LaRocca, PM 15 Corrections to the Avermectin TAS Analysis of 7/6/89.
Document (PDF) (467 KB PDF).
Attachment(s) Following:
July 06, 1989. Memorandum.
J. Robert Tomerlin. Science Analysis and Coordination Branch.
Chronic and Acute Dietary Exposure Analysis for the Proposed
Use of Avermectin on Citrus, PP#8F3592/FAP#8H5550.
*End of Attachments*
August 02, 1989. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - Agri-Mek 0.15 EC - PP #8F3592, FAP
#8H5550 - Avermectin in/on Citrus - Submission of Revised Section F.
Document (PDF) (120 KB PDF).
Attachment(s) Following:
July 07, 1989. Memorandum. 1 Page(s).
J. R. Tomerlin. Tolerance Assessment System Staff.
Corrections to the Avermectin TAS Analysis of 7/6/89.
*End of Attachments*
August 08, 1989. Memorandum. 3 Page(s).
Stephanie Willett. Dietary Exposure Branch.
PP#8F3592/FAP#8H5550. Abamectin (Avermectin B1) on Citrus. Revisions to
Section F and Enforcement Methodology. DEB Nos. 5509, 5510, 5629, 5630.
MRID Numbers 41165300, -01.
Document (PDF) (155 KB PDF).
August 08, 1989. Review. 4 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No. 618-97. Abamectin. Registrant Response to Previous EEB Review Relative
to Conditional Reg. (Granted by RD without EEB Concurrence) for Cotton and Citrus.
Document (PDF) (401 KB PDF).
August 10, 1989. Review. 7 Page(s).
Cynthia Moulton. Ecological Effects Branch.
Reg. No. 89-AZ-05. Agri-Mek 0.15 EC. Proposed Section 18 for Use on Head Lettuce.
Document (PDF) (352 KB PDF).
August 21, 1989. Memorandum. 16 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - 89-AZ-05 - Section 18 Request by the State
of Arizona to Use Avermectin on Head Lettuce. Pgs. 4-7 deleted, draft label.
Inert ingredient info on pgs. 8, 14, 15 not included.
Pending registration info on p. 16 removed.
Document (PDF) (940 KB PDF).
August 24, 1989. Review. 4 Page(s).
Clyde Houseknecht. Ecological Effects Branch.
Reg. No. 89-TX-22. Abamectin (Avid 0.15 EC). Proposed Section 18 for Use on Celery.
Document (PDF) (169 KB PDF).
September 07, 1989. Note. 1 Page(s).
J. R. Tomerlin. Tolerance Assessment System Staff.
Avermectin Exposure Analysis.
Document (PDF) (21 KB PDF).
September 08, 1989. Review. 3 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No. 62476-EUP-12. Avid. Does Proposed Use Warrant an EUP.
Document (PDF) (131 KB PDF).
September 11, 1989. Memorandum. 2 Page(s).
Stephanie Willett. Dietary Exposure Branch.
PP# 8F3592. Method Validation Evaluation of Avermectin in Citrus.
No MRID Number. No DEB Number.
Document (PDF) (83 KB PDF).
September 11, 1989. Review. 4 Page(s).
Clyde Houseknecht. Ecological Effects Branch.
Reg. No. 89-FL-20. Abamectin (Agri-Mek 0.15 EC).
Proposed Section 18 for Use on Strawberries.
Document (PDF) (212 KB PDF).
September 26, 1989. Memorandum. 19 Page(s).
William Dykstra. Toxicology Branch.
Avermectin (Also Called Abamectin) - 89-FL-20 - Section 18 Request by the State
of Florida to Use Avermectin on Straw-berries. Pgs. 4-10 deleted, draft label.
Inert ingredient info on pgs. 11, 17, 18 deleted.
Pending registration info on p. 19 deleted.
Document (PDF) (920 KB PDF).
September 27, 1989. Memorandum. 4 Page(s).
James Akerman. Ecological Effects Branch.
Avermectin Section 18's.
Document (PDF) (214 KB PDF).
September 28, 1989. Note to File. 3 Page(s).
Dan Rieder. Ecological Effects Branch.
Meeting with Merck and PM on Field Testing Requirements for Abamectin.
Pending registration information on pages 1 and 2 is not included.
Document (PDF) (152 KB PDF).
November 03, 1989. Memorandum. 2 Page(s).
James Akerman. Ecological Effects Branch.
Request for EEC Calculation from Environmental Fate and Ground Water Branch.
Reg. Nos. 618-97 and -98.
Document (PDF) (85 KB PDF).
December 15, 1989. Memorandum. 17 Page(s).
Stephanie Willett. Dietary Exposure Branch.
PP# 9F3703/9H5570. Abamenctin (Avermectin B1) on Tomatoes. Evaluation of
Analytical Methodology and Residue Data. MRID Nos. 408709-00 thru-20.
DEB Nos. 4627, 4628, 4629.
Document (PDF) (1097 KB PDF).
December 27, 1989. Review. 4 Page(s).
Daniel Rieder. Ecological Effects Branch.
Reg. No. 90-FL-03. Agri-Mek 0.15 EC. Section 18 Use on Celery in Florida
to Control Two-Spotted Spider Mite.
Document (PDF) (178 KB PDF).
January 08, 1990. Review. 1 Page(s).
Michael Clifford. Registration Support Branch.
EPA File Synbol 475-EII. Black Flag Fatal Attraction. Registration of the End-Use
Product for Killing Roachs. Product ingredient source information is not included.
Document (PDF) (77 KB PDF).
January 18, 1990. Review. 12 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg. # 618-OT. Review adsorption/desorption study (needed to register
product on tomatoes) MRID# 40856301. Pages 7-12 removed, registrant data.
Document (PDF) (239 KB PDF).
January 19, 1990. Memorandum. 5 Page(s).
Richard Griffin. Science Analysis & Coordination Branch.
Revised Chronic Exposure Analysis for the Use of Avermectin on Citrus (DRES).
Document (PDF) (321 KB PDF).
January 23, 1990. Review. 2 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No. 62476-EUP-1. Avid 0.15 EC Miticide.
Review of EUP to Control Feral Honey Bee Colonies.
Document (PDF) (90 KB PDF).
February 23, 1990. Review. 8 Page(s).
Harry Winnik. Ecological Effects Branch.
Reg. No. 90-OR-04. Agri-Mek (Avermectin B1, 0.15 EC). Section 18 for Pears.
Document (PDF) (418 KB PDF).
March 29, 1990. Memorandum. 1 Page(s).
Curt Lunchick. Science Analysis & Coordination Branch.
Exposure Assessment for Workers Exposed to Avermenctin B1 Applied to Cotton,
Celery, and Tomatoes.
Document (PDF) (48 KB PDF).
April 03, 1990. Review. 7 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg. # 618-97, 618-98 Review field dissipation studies to support conditional
registration of product for use on cotton and citrus MRID 411915-01.
Document (PDF) (354 KB PDF).
April 04, 1990. Review. 2 Page(s).
James Akerman. Ecological Effects Branch.
File or Reg. No. 618-98; 618-97 Review progress report and request for extension.
Document (PDF) (81 KB PDF).
April 16, 1990. Review. 3 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg./File #: 618-98 Review attached labeling and data on file for avermectin B1
to support the proposed use on pears.
Document (PDF) (128 KB PDF).
May 04, 1990. Memorandum. 6 Page(s).
Stephanie Willett. Dietary Exposure Branch.
PP Nos. 8F3649 and 9F3703/9H5570. Abamectin (Avermectin B1) on Celery
and Tomatoes. Evaluation of Amendments dated 12/15/89 and 1/31/90.
MRID No. 413284-01. DEB Nos. 6198, 6199, 6334, 6336.
HED Project Numbers 0-0457, 0-0669A.
Document (PDF) (339 KB PDF).
May 29, 1990. Review. 2 Page(s).
William Woodrow. Registration Support Branch.
Data Review for Skin Sensitization Testing (81-6). Accession No. 252113.
Document (PDF) (112 KB PDF).
May 30, 1990. Memorandum. 1 Page(s).
Jerry Stokes. Chemistry Branch.
PP#9F3787. Abamectin in/on pears. Request for Additional Information for the
Submitted Analytical Methodology, Method No. 8000 from Merck. MRID No. 411885-13.
Document (PDF) (57 KB PDF).
June 04, 1990. Memorandum. 3 Page(s).
William Woodrow. Registration Support Branch.
EPA File Symbol 475-EII. Black Flag Fatal Attraction.
Document (PDF) (126 KB PDF).
July 06, 1990. Memorandum. 2 Page(s).
James Akerman. Ecological Effects Branch.
Request for Environmental Fate & Groundwater Branch to Review a Drift
Study with Avermectin.
Document (PDF) (63 KB PDF).
July 17, 1990. Review. 72 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Aquatic EEC [Estimated Environmental Concentration] Avermectin.
Document (PDF) (3966 KB PDF).
August 01, 1990. Memorandum. 1 Page(s).
Curt Lunchick. Non-Dietary Exposure Branch.
Occupational Exposure Resulting From Proposed Application of Avermectin
to Pears (INTRA-0055).
Document (PDF) (60 KB PDF).
September 12, 1990. Memorandum. 4 Page(s).
Jerry Stokes. Chemistry Branch.
PP#9F3787. Abamectin in/on pears. Petition Method Validation Request.
MRID Nos. 412064-01 & 411885-01 thru -16.
Document (PDF) (138 KB PDF).
January 15, 1991. Memorandum. 2 Page(s).
Lucy Markarian. Registration Support Branch.
EEPA Reg. No./File Symbol 618-96 Zephyr 0.15 EC acute toxicity.
Inert ingredient info on page 2 not included.
Document (PDF) (207 KB PDF).
February 19, 1991. Memorandum. 15 Page(s).
Lucy Markarian. Registration Support Branch.
EPA Reg. No./File Symbol 618-97 MK-0936 Citrus Spray Formulation
Inert ingredient info on pages 2, 4-15 is not included. Acute toxicity.
MRID: none. Report No. 90-147-0, TT#90-2740 TT#90-2741, TT#90-2797.
Document (PDF) (1293 KB PDF).
March 22, 1991. Memorandum. 11 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#1G3930. Temporary Tolerance and Experimental Use Permit for Use
of Avermenctin B1 on Apples. EUP-618. (No MRID #. DEB#7427).
Document (PDF) (863 KB PDF).
April 18, 1991. Review. 3 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Reg./File #: 618-97, 618-98 Request meeting with EFGWB to discuss results of field
dissipation study, and review letter of proposed soil sample analyses to satisfy
requirements of field dissipation study.
Document (PDF) (179 KB PDF).
June 07, 1991. Analysis. 9 Page(s).
Stephen Schaible. Science Analysis & Coordination Branch.
Dietary Exposure Analysis for the Section 18 Proposed Use of Avermectin B1 on
Hops (91-WA-0016).
Document (PDF) (748 KB PDF).
June 17, 1991. Review. 11 Page(s).
James Akerman. Ecological Effects Branch.
File or Reg. No. 618-98, 618-97 Proposed label restriction to citrus and cotton
uses to reduce aquatic organism exposure.
Document (PDF) (809 KB PDF).
July 09, 1991. Memorandum. 1 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#1G3930. Addendum for Temporary Tolerance for Avermenctin B1 on Apples.
(No MRID # or DEB#).
Document (PDF) (67 KB PDF).
July 09, 1991. Memorandum. 12 Page(s).
Jerry Stokes. Chemistry Branch.
PP#9F3787. Avermectin B1 in/on pears. Evaluation of Analytical
Method and Residue Data. MRID Nos. 412064-01 & 411885-01 thru -16.
Document (PDF) (907 KB PDF).
November 05, 1991. Memorandum. 14 Page(s).
Jerry Stokes. Chemistry Branch.
PP#0F3880. Avermectin B1 in/on strawberries.
Evaluation of Analytical Method & Residue Data.
MRID Nos. 415405-00, thru -019.
Document (PDF) (1106 KB PDF).
November 26, 1991. Memorandum. 24 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F03973 & 1H05611. Abamectin (Avermectin B1) for Use in/on Almonds, Walnuts,
& Head Lettuce. Evaluation of Analytical Methodology & Residue Data.
MRID Nos. 418225-00 & -01 (21 Volumes) & 418225-02 (11 Volumes).
Document (PDF) (2123 KB PDF).
February 19, 1992. Review. 6 Page(s).
Ecological Effects Branch..
Amend Label, Consider Proposed Use on Strawberries, Head Lettuce, Almonds,
Walnuts, Pears, Tomatoes, Celery.
Document (PDF) (377 KB PDF).
Attachment(s) Following:
February 19, 1992. Memorandum.
Douglas Urban. Ecological Effects Branch.
Adverse Effects from Use of Avermectin.
*End of Attachments*
February 29, 1992. Memorandum. 33 Page(s).
Mark Law. Analytical Chemistry Section.
PP#9F3787. Abamectin in/on Pears. (MRID#'s 412064-01, 411885-01 to -16, DEB #5700).
Petition Method Validation Report.
Document (PDF) (1378 KB PDF).
March 03, 1992. Memorandum. 21 Page(s).
William Woodrow. Registration Support Branch, RD.
EPA Reg. No. 618-96, 618-97 Avid 0.15 EC, Zephyr 0.15 EC [acute toxicity]
Inert ingredient info on pages 3-4 not included.
MRID 420203-01, -02, -04, 420798-01, 420800-01, 409125-01.
Document (PDF) (1466 KB PDF).
March 26, 1992. Memorandum. 2 Page(s).
Douglas Urban. Ecological Effects Branch.
Review Environmental Chemistry Method.
Document (PDF) (114 KB PDF).
Attachment(s) Following:
March 26, 1992. Memorandum.
Douglas Urban. Ecological Effects Branch.
Review of Environmental Chemistry Method for Avermectin Record # 264087.
*End of Attachments*
April 16, 1992. Memorandum. 2 Page(s).
Jerry Stokes. Chemistry Branch.
PP#9F3787. Abamectin in/on pears. Results of Petition Method Validation.
MRID No. 411885-15.
Document (PDF) (139 KB PDF).
July 08, 1992. Review. 3 Page(s).
Henry Nelson. Envirnomental Fate & Ground Water Branch.
Two products: Agrimek and Zephyr Request that
spray drift loading assumption be lowered.
Document (PDF) (470 KB PDF).
August 18, 1992. Memorandum. 1 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#1G3930. Request for Extension of Temporary Tolerance and Experimental
Use Permit for Use of Avermectin B1 on Apples. EUP-618.
(No MRID #. CBTS#10149. Barcode D179725).
Document (PDF) (67 KB PDF).
September 09, 1992. Efficacy Review. 1 Page(s).
Vern McFarland. Insecticide Rodenticide Branch.
File or Reg. No. 499-322. Product Name(s): Whitmire Avert® PT 300 Pressurized Bait.
Provide performance data in form of reprint article supporting effectiveness of
abamectin bait against pyrethroid-resistant cockroaches.
MRID No.: 423999-01; D180823.
Document (PDF) (34 KB PDF).
September 23, 1992. Memorandum. 3 Page(s).
Debra Edwards. Chemistry Branch.
Anticipated Residues of Avermectin in/on Orange Juice, Orange Pulp and Milk
(Section 3 Use); and Fresh Market Apples (EUP) to be Used in Acute Dietary
Risk Assessment.
Document (PDF) (217 KB PDF).
September 24, 1992. Memorandum. 2 Page(s).
Debra Edwards. Chemistry Branch.
Amendment of 9/23/92 Memo re. Anticipated Residues of Avermectin For Use
in Acute Dietary Risk Assessment.
Document (PDF) (69 KB PDF).
September 28, 1992. Memorandum. 22 Page(s).
Doug Urban. Ecological Effects Branch.
Aquatic Mesocosm Protocol Review.
Document (PDF) (1474 KB PDF).
Attachment(s) Following:
September 16, 1992. Review.
Douglas Urban. Ecological Effects Branch.
Review of Aquatic Mesocosm Protocol Control of Mites
& Leafminers on Tree, Vegetable & Field Crops.
*End of Attachments*
September 30, 1992. Memorandum. 36 Page(s).
Han Tai. Ecological Effects Branch.
Avermectin Method Validation - Report No. ECM-0001.
Page 34 removed, registrant data.
Document (PDF) (1521 KB PDF).
October 26, 1992. Memorandum. 4 Page(s).
Joel Garbus. Chemistry Branch Tolerance Support.
PP#2H5642: Abamectin (EPA Reg No 499-294): Residue Data in Support of
Proposed New Use in Food Handling Establishments. DP Barcodes 179196
and 179198 CBTS Nos 10037 and 10038 MRID 423325-00.
Document (PDF) (251 KB PDF).
November 26, 1992. Memorandum. 2 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#1G3930. Revised Section F. Temporary Tolerance and Experimental
Use Permit for the Use of Avermectin B1 on Apples. EUP-618
(No MRID#, CB#10641, Barcode#D182970).
Document (PDF) (84 KB PDF).
November 26, 1992. Memorandum. 2 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#9F3787. Revised Section F. Avermectin B1 in/on pears.
(No MRID#, CB#10644, Barcode#D182971).
Document (PDF) (84 KB PDF).
May 10, 1993. Review. 11 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
ID# 618-97. Review additional soil analyses to satisfy requirements of previous
field dissipation study. Pages 6-11 removed, registrant data. MRID 426276-01.
Document (PDF) (369 KB PDF).
May 17, 1993. Memorandum. 37 Page(s).
William Dykstra. Toxicology Branch I.
Avermectin (Also Called Abamectin); PP #1G03930;
Extension of Temporary Tolerances on Apples; Resubmission; Merck & Co.
Pages 34-36 removed, registrant data. MRID 42612302. Tox Review 010260.
Document (PDF) (1823 KB PDF).
June 14, 1993. Memorandum. 3 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#0F3880. Amendment dated April 1, 1993 for Abamectin in/on strawberries.
Evaluation of Analytical Method and Residue Data.
(MRID#'s 427255-00, -01 and -02, CB#'s 11723 and 11724, Barcode# D190265).
Document (PDF) (191 KB PDF).
July 08, 1993. Memorandum. 32 Page(s).
Roger Gardner. Toxicology Branch.
Developmental and Reproductive Toxicity Peer Review of Avermectin.
Document (PDF) (1913 KB PDF).
July 21, 1993. Memorandum. 17 Page(s).
Paul Zubkoff. Environmental Fate & Ground Water Branch.
Review of Public Materials submitted by Merck & Co. in support of their voluntary
product restrictions & assessment that aquatic exposure due to potential runoff of
Avermectin B1 is less than previously estimated.
Document (PDF) (865 KB PDF).
August 12, 1993. Memorandum. 3 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Mammal Field Study Waiver Request.
Document (PDF) (130 KB PDF).
Attachment(s) Following:
August 12, 1993. Memorandum.
Anthony Maciorowski. Ecological Effects Branch.
Review Response for Wild Mammal field Study.
*End of Attachments*
August 16, 1993. Review. 15 Page(s).
Paul Zubkoff. Environmental Fate & Ground Water Branch.
Review of public materials submitted by Merck & Co. in support of their voluntary
product restrictions and assessment that aquatic exposure due to potential runoff
of Avermectin B1 is less than previously estimated.
Document (PDF) (822 KB PDF).
September 16, 1993. Memorandum. 2 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
D192285; D192281; D194892; EEB needs a quantitative model run by EFGWB that will defend
or refute the registrant's use mitigation proposals for avermectin registration.
Document (PDF) (118 KB PDF).
October 05, 1993. Review. 6 Page(s).
Indira Gairola. Residue Chemistry Branch.
Product Chemistry Review for End-Use Products: Avert Prescription Treatment
TC 93B Bait; File Symbol 499-URN; Abamectin. MRID No. 429362-01.
Document (PDF) (244 KB PDF).
November 04, 1993. Review. 2 Page(s).
Alfred Smith. Residue Chemistry Branch.
Product Chemistry Review for End-Use Products: Avert Prescription Treatment
TC 93A Bait; File Symbol 499-URN; Abamectin. MRID No. 42905501.
Document (PDF) (94 KB PDF).
November 09, 1993. Memorandum. 2 Page(s).
Paul Zubkoff. Environmental Fate & Ground Water Branch.
Use of Avermectin B1 on Vegetable Crops (strawberries, tomatoes, celery and
head lettuce) in Western Region (California, Arizona and Texas) and Florida.
Document (PDF) (130 KB PDF).
December 09, 1993. Review. 4 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Reg./File # 000618-00097 Section 3 Registration... for use of avermectin
on strawberries, tomatoes, celery and lettuce End of Dec. 2000.
Document (PDF) (199 KB PDF).
December 16, 1993. Memorandum. 6 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F3787. Abamectin (Avermectin B1) for Use in/on Pears. Registrant's Response
of 3/10/93 to Analytical Method Deficiencies Cited in J. Stokes Memo of 4/16/92.
MRID No. 426922-01.
Document (PDF) (420 KB PDF).
February 03, 1994. Memorandum. 11 Page(s).
Jerry Stokes. Chemistry Branch -Tolerance Support.
PP#1G3930. Request to Decrease the Temporary Tolerance and to Extend the
Experimental Use Permit for the Use of Avermenctin B1 on Apples. 618-EUP-13.
(MRID# 430131-01, CBTS#12909. DP Barcode 197373).
Document (PDF) (710 KB PDF).
May 09, 1994. Memorandum. 15 Page(s).
James Kariya. Dietary Risk Evaluation Section/HED.
Avermectin on Tomatoes at 0.01 ppm (PP#9F3703):
Estimates of dietary exposure and risk. TAS.
Document (PDF) (933 KB PDF).
May 17, 1994. Memorandum. 14 Page(s).
Mary Peters. Chemistry Branch -Tolerance Support.
PP#3F04258, Abamectin (AGRI-MEK 0.15 EC, EPA Reg. No. 618-98) in or on the
fruiting vegetables crop grouping. Evaluation of analytical method and residue data.
CBTS# 12519, 13174; DP Barcode D194897, D198987; MRID 429000- 00, -01.
Document (PDF) (1048 KB PDF).
May 18, 1994. Memorandum. 7 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F03973 & 1H05611. Abamectin (Avermectin B1) for Use in/on Almonds, Walnuts,
& Head Lettuce. Registaant's Response to Conclusions/Deficiences Outlined
in Memo of G.J. Herndon Dated 11/26/91. MRID Nos. 427652-01 & -02 (12 Volumes).
Document (PDF) (298 KB PDF).
May 19, 1994. Memorandum. 15 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F03973 & 1H05611. Abamectin (Avermectin B1) for Use in/on Almonds,
Walnuts, & Head Lettuce. Registrant's Response to Conclusions/Deficiences
Outlined in Memo of G.J. Herndon...MRID Nos 42949801 & 02 (22 Volumes).
Pgs. 11-15 removed,Draft Product Label.
Document (PDF) (639 KB PDF).
June 02, 1994. Memorandum. 11 Page(s).
Michael Flood. Chemistry Branch-Tolerance Support.
PP#4G4295 -- Abamectin (AGRI-MEK/AVID 0.15 EC Miticide/Insecticide)
for Use in/on Potatoes. Merck & Co.'s Submission Dated 11/24/93.
EPA Reg. Nos. 618-98/618-96. DP Barcode: D199136. MRID 43035201.
Document (PDF) (786 KB PDF).
August 24, 1994. Review. 6 Page(s).
Shyam Mathur. Registration Support Branch.
Product Chemistry Review of Whitmire PT 320 Avert Gel A; DP Barcode D205684;
Reg. No. 499-GOU. Inert info on page 1 & 3 and manufacturing process info
on page 6 not included. MRID 42644501.
Document (PDF) (305 KB PDF).
October 21, 1994. Memorandum. 4 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#9F03787. Abamectin (Avermectin B1) for Use in/on Pears.
Initiation of Petition method Validation Request. MRID No. 426922-01.
Document (PDF) (162 KB PDF).
October 27, 1994. Memorandum. 8 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#9F03787. Abamectin (Avermectin B1) for Use in/on Pears. Review of Additional
Residue Data Submitted in Support of Reducing the Pending Tolerance from 0.05 to
0.02 ppm. MRID No. 430054-01 (6 Volumes).
Document (PDF) (470 KB PDF).
November 03, 1994. DER. 15 Page(s).
Paul Chin. Toxicology Branch.
Deoxy Avermectin Study Type: Metabolism - rats
Pages 12-15 removed, registrant data. MRID 42851523, 42851524.
Document (PDF) (404 KB PDF).
November 16, 1994. Memorandum. 2 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04373. Abamectin (Avermectin B1) for Use in/on Head Lettuce. [Previously PP#1F03973
& 1H05611. Abamectin (Avermectin B1) for Use in/on Almonds, Walnuts & Head. Lettuce].
Separation of head Lettuce...Response to Memo of Herndon dated 5/19/94.
Document (PDF) (96 KB PDF).
December 21, 1994. Memorandum. 31 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#9F03787. Abamectin (Avermectin B1) for Use in/on Pears. Anticipated Residues
of Abamectin in/on Crops With Established Tolerances (Celery, Citrus, Cotton, Lettuce,
Strawberries, & Tomatoes) & Pending Tolerances Which have Only Minor CBTS/CBRS….
Document (PDF) (1958 KB PDF).
Attachment(s) Following:
December 21, 1994. Memorandum.
G. Jeffrey Herndon. Chemistry Branch I.
Data Deficiencies (Almonds, Pears, & Walnuts) to be Used
in Both Acute and Chronic Dietary Risk Assessments.
*End of Attachments*
January 28, 1995. Memorandum. 38 Page(s).
Teung Chin. Dietary Risk Evaluation Section/HED.
Acute Dietary and Chronic Exposure Analysis for a Permanent Tolerance of
Avermectin B1 in/on Pears (PP# 9F3787).
Document (PDF) (2189 KB PDF).
February 06, 1995. Memorandum. 15 Page(s).
William Wassell. Chemistry Branch - Tolerance Support.
PP#4E04419. Abamectin (AGRI-MEK 0.15EC miticide/insecticide, EPA Reg No 618-98)
in or on Hops. Evaluation of analytical methods, magnitude of the residue and
storage stability data MRID Nos. 433791-01, 434515-01.
Document (PDF) (1034 KB PDF).
March 27, 1995. Memorandum. 4 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on Cucurbits.
Initiation of Petition Method Validation Request. MRID NOs. 432038-01 & 432286-01.
Document (PDF) (146 KB PDF).
March 29, 1995. Memorandum. 17 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on the Cucurbits Crop Group
(Cucumbers, Melons, & Squash). Evaluation of Analytical Methodology & Residue Data.
MRID Nos. 432038-01 (8 Volumes) & 432286-01 (1 Volume).
Document (PDF) (1001 KB PDF).
April 24, 1995. Memorandum. 10 Page(s).
William Cutchin. Chemistry Branch-Tolerance Support.
PP#3F4258, PP#1F3973/1H5611 Abamectin in or on bell peppers.
Registrant's response to CBTS review (6/21/94) and additional bell pepper residue data.
CBTS# 14207; DP Barcode D206550; MRID#433346-00: MRID#42949801, Fax 4/19/95.
Document (PDF) (642 KB PDF).
May 03, 1995. Memorandum. 22 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on Apples.
Evaluation of Analytical Methodology & Residue Data.
Document (PDF) (1351 KB PDF).
May 17, 1995. Memorandum. 4 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Risk Assessment for Avermectin used on vegetables & other Field Crops, Nationwide.
Document (PDF) (242 KB PDF).
May 31, 1995. Memorandum. 11 Page(s).
David Ritter. Registartion Support Branch, RD.
EPA Reg. #: 618-96/97/98 Abamectin 0.15 EC Review acute dermal toxicity and
dermal sensitization. Consider waiving requirement for dermal irritation study.
MRID 429836-01, -02.
Document (PDF) (560 KB PDF).
June 06, 1995. DER. 17 Page(s).
George Tompkins. Environmental Fate & Ground Water Branch.
Type of Study: Leaching and Adsorption/Desorption (163-1)
Pages 3-17 removed, registrant data. MRID 42851526.
Document (PDF) (151 KB PDF).
June 06, 1995. Review. 9 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
3G04239, 618-EUP-RU. Review of environmental fate studies in support
of EUP and for registration of MK-0244. Page 9 removed, registrant data.
MRIDs 42743642, 43404301 to -06, 42851526, 43393005.
Document (PDF) (484 KB PDF).
July 19, 1995. Review. 5 Page(s).
Indira Gairola. Registration Support Branch.
Product Chemistry Review of Whitmire TC-149A; DP Barcode No. D216998;
Reg/File Symbol 499-UGU; Abamectin. MRID No. 43695501.
Inert ingredient info on page 3 not included.
Document (PDF) (248 KB PDF).
September 14, 1995. Memorandum. 17 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F3787. Abamectin (Avermectin B1) for Use in/on Pears. Results of Beltsville's
Method Validation (Memo of E. Greer & D. Wright, Jr. dated 5/15/95).
Document (PDF) (1037 KB PDF).
September 18, 1995. Memorandum. 16 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on the Cucurbit Crop
Group (Cucumbers, Melons, & Squash. Results of ACL's Method Validation
(Memo of E. Greer, Jr. & D. Wright, Jr. dated 8/4/95).
Document (PDF) (919 KB PDF).
September 20, 1995. Memorandum. 1 Page(s).
Shyam Mathur. Registration Support Branch.
Product Chemistry Review of Whitmire PT 320 Avert Gel; DP Barcode D205684;
Reg. No. 499-GOU; End Use.
Document (PDF) (68 KB PDF).
September 21, 1995. Memorandum. 3 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on the Cucurbit Crop Group
(Cucumbers, Melons, & Squash). Registrant's Submission of 6/16/95 to Deficiencies
Raised in the 3/29/95 Memo of C.J. Herndon.
Document (PDF) (167 KB PDF).
September 26, 1995. Review. 7 Page(s).
Shyam Mathur. Registration Support Branch.
Product Chemistry Review of Whitmire TC-141 Avert Bait Powder;
DP Barcode No. D217890; Reg/File Symbol 499-UGG; Abamectin.
Inert info on page 6 and manufacturing process info on page 7 not included.
MRID 43694001.
Document (PDF) (280 KB PDF).
October 06, 1995. Memorandum. 15 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
Revised Labels for Addressing the Application of Concentrated Sprays of Abamectin
(Avermectin B1) to Tree Crops. Impact on Various Pending and Registered Uses:
Almonds & Walnuts (PP#1F3973/FAP#1H561) Apples…
Pages 8-15 removed, draft label information.
Document (PDF) (442 KB PDF).
October 17, 1995. Memorandum. 10 Page(s).
Brian Steinwand. Science Analysis Branch/HED.
Dietary Exposure Analysis for Avermectin B1 in/on Pears. PP# 1F3787.
Document (PDF) (633 KB PDF).
October 30, 1995. Memorandum. 4 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F03973 & 1H05611. Abamectin (Avermectin B1) for Use in/on Almonds
& Walnuts. Registrant's Response to Conclusions/Deficiences Outlined in
Memo of C.J. Herndon Dated 5/19/1994.
Document (PDF) (217 KB PDF).
November 28, 1995. Memorandum. 2 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#1F03787. Abamectin (Avermectin B1) for Use in/on Pears. Merck's Response of
10/31/95 to the Lone Remaining Deficiencyficiency as Outlined in the Memo of G.J.
Herndon Dated 9/14/95. MRID No. 438325-01.
Document (PDF) (128 KB PDF).
December 05, 1995. Memorandum. 20 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#5F04508. Abamectin (Avermectin B1) for Use in/on Pototoes. Evaluation of
Analytical Methodology & Residue Data. MRID Nos. 436233-01 (7 Volumes) & 436233-02.
Document (PDF) (1278 KB PDF).
December 11, 1995. Memorandum. 2 Page(s).
G. Jeffrey Herndon. Chemistry Branch I.
PP#4F04354. Abamectin (Avermectin B1) for Use in/on the Cucurbit Crop Group
(Cucumbers, Melons, & Squash). Merck's Response of 11/6/95 to the Lone
Remaining Deficiency as Outlined in the Memo of G.J. Herndon dated 9/19/95.
MRID No. 438383-01.
Document (PDF) (119 KB PDF).
March 05, 1996. Memorandum. 12 Page(s).
William Wassell. Chemistry Branch - Tolerance Support.
PP#5E04566. Abamectin (AGRI-MEK 0.15EC miticide/insecticide, EPA Reg. No. 618-98)
in or on Hops. Evaluation of analytical methods and magnitude of the residue data.
MRID No. 437331-01, Chemical Code: 122804.
Document (PDF) (511 KB PDF).
March 07, 1996. Memorandum. 6 Page(s).
William Wassell. Chemistry Branch - Tolerance Support.
PP#4E04419. Abamectin (AGRI-MEK 0.15EC miticide/insecticide EPA Reg. No. 618-98)
in or on Hops. Amendment of 6/8/95. MRID No. 436801-01. CBTS No. 15854;
Barcode: D217347.
Document (PDF) (296 KB PDF).
June 17, 1996. Memorandum. 6 Page(s).
William Wassell. Chemistry Branch - Tolerance Support.
PP#5E4566. Abamectin (AGRI-MEK 0.15EC Miticide/Insecticide, EPA Reg No 618-98)
in or on Hops. Amendment of 2/22/96. MRID Nos. 439709-01, 440076-01.
Document (PDF) (260 KB PDF).
June 19, 1996. Review. 2 Page(s).
Sami Malak. Registration Support Branch.
Product Chemistry Review of Whitmire TC-181; DP Barcode No. D226908;
Reg/File Symbol 499-UAT; Abamectin. MRID No. 44021001.
Document (PDF) (128 KB PDF).
January 10, 1997. Memorandum. 17 Page(s).
G. Jeffrey Herndon. Risk Characterization & Analysis Branch.
PP#7F3500, #8F3592, and #5E4566. Use of Avermectin B1 on Cotton, Citrus and Hops.
Extension of Time-Limited Tolerances.
Document (PDF) (1152 KB PDF).
September 16, 1998. Memorandum. 19 Page(s).
William Cutchin. Registration Action Branch HED.
PP# 7F4844 AVERMECTIN. Request for Tolerances on Grapes, Raisins and Peppers.
Evaluation of Analytical Method and Magnitude of the Residue Data.
Document (PDF) (1061 KB PDF).
February 08, 1999. Memorandum. 16 Page(s).
William Cutchin. Registration Action Branch HED.
Avermectin. Anticipated Residues for the Human Health Risk Assessment for the
Request for Tolerances on Grapes, Raisins, and Peppers. DP Barcode: D252609.
Document (PDF) (844 KB PDF).
February 23, 1999. Memorandum. 35 Page(s).
William Cutchin. Registration Action Branch HED.
Avermectin. Acute and Chronic Dietary Analysis for the Request for Tolerances
on Grapes and Peppers and Section 18 on Avocados. DP Barcode: D252974.
Document (PDF) (1425 KB PDF).
July 01, 1999. Memorandum. 2 Page(s).
Douglas Dotson. Residue Analysis Branch 2/HED.
ID#s: 0F3380 and 4E4419 Review of Storage Stability Studies of
Avermectin in Strawberries and Dried Hops MRID 447085-02, -01.
Document (PDF) (102 KB PDF).
July 21, 1999. Memorandum. 12 Page(s).
Douglas Dotson. Residue Analysis Branch 2/HED.
PP#: 7F3500 Tolerance Petition for the Residues of Avermectin in or on Cotton Gin
Byproducts Evaluation of Analytical Methodology and Residue Data MRID 447085-05.
Document (PDF) (704 KB PDF).
April 20, 2000. Memorandum. 23 Pages.
Stephanie Syslo & James Carleton. Environmental Risk Branch II.
Tier I Drinking Water EECs for Abamectin on Leafy and Fruiting Vegetables and
Plums; Recalculated Tier II Drinking Water EECs for Abamectin on Strawberries
in Florida Incorporating the Index Reservoir and the Percent Cropped Area.
DP Barcode: D265145.
Document (PDF) (911 KB PDF).
June 15, 2000. Memorandum. 29 Pages.
Stephanie Syslo et al. Environmental Risk Branch II.
Review of Proposed amendment to Abamectin label to add uses on plums/prunes,
leafy vegetables, and fruiting vegetables. DP Barcode: D262129.
Document (PDF) (966 KB PDF).
May 04, 2001. Review. 4 Page(s).
Sami Malak. Technical Review Branch.
Product Chemistry Review of Whitmire Micro Gen TC-234.0.011% Abamectin;
Reg/File Symbol 499-UOA; MRID No. 45378401. Source of product ingredient on
pages 1, 2 & 3; manufacturing process information on page 4 not included.
Document (PDF) (250 KB PDF).
November 07, 2001. Review. 2 Page(s).
Indira Gairola. Technical Review Branch.
Product Chemistry Review of EP [X] DP Barcode No.: D278196
Reg/File Symbol No.:100-895 Updated Basic CSF for Abamectin
Technical with greater purity.
Document (PDF) (67 KB PDF).
November 29, 2001. Memorandum. 2 Page(s).
Michele Mahoney. Environmental Risk Branch.
Decision to disregard the study entitled, "Adsorption/ desorption of C14-avermectin
B1a on agricultural plastic mulch" (MRID 45500501) due to deviation in the protocol.
Attached: November 15th, 2001 Memorandum; Subject: Errors in MRID 45505501...
Document (PDF) (72 KB PDF).
September 19, 2002. Review. 1 Page(s).
Sami Malak. Technical Review Branch.
Product Chemistry Review of: Technical Grade Active Ingredient. DP Barcode No.:283804.
Reg/File Symbol 100-895. Product Name: Affirm Technical, 70% Abamectin water solubility
MRIDs: 45096701.
Document (PDF) (51 KB PDF).
December 10, 2002. Memorandum. 17 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: Abamectin Technical; EPA Reg No. 72167-EN;
DP Barcode: D285183; PC Code 122804. MRID 45544005.
Document (PDF) (919 KB PDF).
December 30, 2002. Memorandum. 16 Pages.
Byron Backus. Technical Review Branch.
Product Name: NATIONS AG II ABAMECTIN 0.15 EC EPA File Symbol: 72167-EE
DP Barcode: D285189 Case No: 072417 Submission: S621027.
MRIDs 45708003, 45708004, 45708005, 45708006, 45712807, 45708007….
Document (PDF) (786 KB PDF).
November 20, 2003. DER. 9 Page(s).
Jose Morales. Reregistration Branch HED.
Abamectin/PP#2H5642/PC Code 122804/DP Barcode D283818 DACO 7.8/OPPTS 860.1460
Food Handling Establishments MRIDs 44878101, 44933401, -02, -03.
Document (PDF) (367 KB PDF).
January 13, 2004. Memorandum. 5 Page(s).
Shyam Mathur. Technical Review Branch.
Revised Product Chemistry Review of Nations AG II Abamectin Technical.
Product ingredient source information on page 1 not included.
Page 3 removed, registrant data. MRID 45544001, 02.
Document (PDF) (235 KB PDF).
February 09, 2004. Review. 4 Pages.
Rosalind Gross. Technical Review Branch.
EPA Reg. No. or File Symbol 4822-LGI. Product Name(s): Raid CWR.
Examine test data to ascertain if CRP is acceptable (Force Testing, Weather
Testing, 3 Month Analytical Summary with % Abamectin loss & bait loss).
DP Barcode: D296828. MRID No.: 461142-04.
Document (PDF) (81 KB PDF).
March 22, 2004. Memorandum. 4 Pages.
Jim Carleton. Environmental Resources Branch II.
Drinking water assessment for abamectin. PC Code: 122804.
DP Barcode: D297214, D297226.
Document (PDF) (186 KB PDF).
April 14, 2004. DER. 6 Page(s).
Jim Carleton. Environmental Risk Branch.
Data evaluation record (DER) for a plasticulture
runoff study on abamectin (MRID 45906202).
Document (PDF) (348 KB PDF).
June 07, 2004. Memorandum. 8 Page(s).
Breann Hanson. Technical Review Branch.
Name of Pesticide Product: Abamectin Technical;
EPA Reg No. 72167-EN; DP Barcode: D300167; PC Code 122804.
Document (PDF) (287 KB PDF).
September 20, 2004. Memorandum. 5 Pages.
Ibrahim Abdel-Saheb. Environmental Resources Branch II.
Revised Drinking water assessment for Avermectin. PC Code: 122804.
DP Barcode: D307962.
Document (PDF) (226 KB PDF).
October 13, 2004. Memorandum. 7 Pages.
Ibrahim Abdel-Saheb. Environmental Resources Branch II.
Revised Drinking water assessment for Abamectin. DP Barcode: D309020.
Document (PDF) (320 KB PDF).
October 18, 2004. Memorandum. 4 Page(s).
Richard Loranger. Health Effects Division.
Abamectin: Potential Impact of Proposed New Technical Grade
Active Ingredient from Nations ag II on Human Exposure & Risk.
Tox Review No. 0051899. Manufacturing Process info removed from pages 2, 3 & 4.
Document (PDF) (246 KB PDF).
November 15, 2004. Memorandum. 109 Pages.
Richard Lee & Ibrahim Abdel-Saheb. Environmental Risk Branch II.
EFED Ecological Risk Assessment for the Section 3 Registration of Abamectin
for foliar uses on Plums/Prunes, Leafy Vegetables, Fruiting Vegetables,
Avocado, Mint, and Basil and seed treatment for Cotton,...
DP Barcodes: D306358, D306359, D306360, D306362.
Document (PDF) (1788 KB PDF).
December 01, 2004. Memorandum. 16 Page(s).
Nancy Dodd. Registration Action Branch.
Abamectin. PP#2H5642. Petition for the Establishment of Permanent Tolerances
for Section 3 Registration for Use in Food Handling Establishments.
Summary of Analytical Chemistry and Residue Data. DP Barcode: D310414
MRIDs: 44878101, 44933401 thru 44933403.
Document (PDF) (610 KB PDF).
December 17, 2004. Memorandum. 15 Page(s).
Breann Hanson. Technical Review Branch.
Name of Pesticide Product: Abamectin Technical EPA File Symbol: 81598-R
DP Barcode: D310857 Review acute toxicology studies.
MRID 46385006 to -10, 45623501.
Document (PDF) (715 KB PDF).
May 16, 2005. Memorandum. 11 Page(s).
Debra Rate. Technical Review Branch.
FEE: Product Chemistry Review of Abamectin Technical. DP Barcode: D310856.
EPA Reg. No: 81598-R MRID Nos. 46385001, -02, -03, -05, -11, 46396701,
46542501. Pages 7-11 removed, manufacturing process and inert info.
Document (PDF) (249 KB PDF).
September 14, 2005. Review. 4 Page(s).
Bruce Kitchens. Technical Review Branch.
EP Product Chemistry Review DP Barcode No.: D318499. REG./File Symbol: 81598-R.
Registrant responding to previous product chemistry review.
MRIDs 46555701, 46563401 (replacing 46550301).
Page 4 removed, manufacturing process information.
Document (PDF) (169 KB PDF).
December 16, 2005. Memorandum. 4 Page(s).
Eugenia McAndrew. Technical Review Branch.
Name of Pesticide Product: Rotam Abamectin Technical EPA File Symbol: 81598-R
DP Barcode: 324491 Address whether acute tox studies for original CSF can be
used with the new CSF. MRID 463850-06 to -10.
Document (PDF) (142 KB PDF).
February 21, 2008. Memorandum. 42 Pages.
Ibrahim Abdel-Saheb. Environmental Risk Branch II.
Drinking water for Abamectin granular product to control fire ants, EC formulation
applied aerially to citrus, and cattle ear tag. DP Barcodes: 346196, 347961, 343413.
Document (PDF) (411 KB PDF).
December 11, 2008. Efficacy Review. 5 Pages.
Kable Bo Davis. EPA/OPP.
PRODUCT: Y-TEX BOVAMECTM Cattle Ear Tags. FILE SYMBOL: 39039-RT.
BARCODE: D359458. PURPOSE: Review data to determine if it supports product registration.
MRIDS: 47600401, 47600402.
Document (PDF) (267 KB PDF).
January 21, 2009. Efficacy Review. 2 Pages.
Kable Bo Davis. EPA/OPP.
PRODUCT: Y-TEX BOVAMECTM Cattle Ear Tags. FILE SYMBOL: 39039-RT.
BARCODE: D360876. PURPOSE: Review rebuttal to Agency efficacy review
dated December 11, 2008 (D359458). MRIDS: N/A.
Document (PDF) (83 KB PDF).
January 27, 2009. Memorandum. 13 Pages.
Thurston G. Morton. Risk Assessment Branch IV.
Abamectin. Revised Review of the Section 3 Registration Request for Ear Tag
Use on Beef Cattle and Non-Lactating Dairy Cattle. EPA File Symbol: 39039-RT.
MRID Nos. 471640-11,-12,-16, 471855-02, -03, 476239-01 thru -06.
DP Barcode: 357192, 360418 & 360699.
Document (PDF) (659 KB PDF).
February 24, 2010. Memorandum. 188 Pages.
Ibrahim Abdel-Saheb. Environmental Risk Branch II.
Ecological risk assessment evaluating Abamectin for the registration of a new
end-use product (Agri-Mek®SC Miticide/Insecticide) for use on almonds, walnuts,
apples, avocados, celeriac, citrus, cotton, cucurbit,...DP Barcode: 365085.
Document (PDF) (2842 KB PDF).