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Index of Cleared Science Reviews for Dicofol (Pc Code 010501)

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March 27, 1981. Memorandum. 51 Page(s).
Tom Edwards. Toxicology Branch.
Reregistration Standard: KELTHANE Acute oral LD50 Rat; MRID 00004373,
00004365, 05002571; Rabbit; 00004374.
Document (PDF) (5042 KB PDF).

May 22, 1981. Memorandum. 35 Page(s).
Charles Bowen. Ecological Effects Branch.
Revised copy of EEB's Kelthane Disciplinary Summary and Data Gaps for fish,
aquatic invertebrates (marine and freshwater), and birds.
Document (PDF) (3881 KB PDF).

May 26, 1981. Memorandum. 2 Page(s).
Cheryl Peterson. Insecticide Rodenticide Branch.
Letter from S.S. Song Dated 5-14-81, EPA Reg. No. 239-741 Ortho Isotox
Insect Spray. Caswell Nos. 160, 93, 455.
Document (PDF) (311 KB PDF).

March 15, 1985. Memorandum. 3 Page(s).
Theodore Farber. Toxicology Branch.
Request to Review an Acute Inhalation Study Using KELTHANE.
Acc. No. 256415. Guideline 81-3.
Document (PDF) (137 KB PDF).

May 13, 1985. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol (010501) - Preliminary Report on Poultry Metabolism Study
[Accession No. 257600, RCB No. 964].
Document (PDF) (246 KB PDF).

May 29, 1985. Memorandum. 2 Page(s).
Susan Hummel. Residue Chemistry Branch.
Comment on Dicofol 3c2b Letter.
Document (PDF) (67 KB PDF).

July 15, 1985. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol Oncogenicity - SAP Meeting July 8, 1985.
Document (PDF) (217 KB PDF).

July 30, 1985. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol Confidential Statement of Formula and Revised Certified Limits.
EPA Reg. No. 707-107 Kelthane Technical [Accession No. 258054, RCB No. 1137].
Page 3 is not included - confidential statement of formula.
Document (PDF) (132 KB PDF).

November 05, 1985. Memorandum. 2 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol PD4 - Comments.
Document (PDF) (64 KB PDF).

January 21, 1986. Memorandum. 8 Page(s).
Susan Hummel. Residue Chemistry Branch.
010501 Amendment - Mitigan Technical (Dicofol) Reduction of DDTr [Accession No. 259801,
RCB No. 136]. Quality control procedure info. on pgs. 2-4 removed. Pgs. 5-8 deleted,
manufacturing process and quality control info., confidential statement of formula.
Document (PDF) (373 KB PDF).

July 17, 1986. Letter. 8 Page(s).
Robert Larkin. Rohm & Haas Company.
Amended Registrations for Kelthane Miticide. New Confidential Statements
of Formula. Commerical/financial information on page 1 is not included.
Manufacturing process info. on page 2 is not included. Pages 3-8 are
not included - manufacturing process info.
Document (PDF) (184 KB PDF).

July 31, 1986. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol - Rohm & Haas. Page 3 is not included - manufacturing process and quality
control procedure information, confidential statement of formula.
Document (PDF) (119 KB PDF).

September 19, 1986. Memorandum. 3 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol - Review of the Rohm & Haas Submission in Response to the "Dicofol
Notice of Intent to Cancel". Manufacturing process information on page 1 is
not included. Page 3 is not included - quality control procedure information.
Document (PDF) (135 KB PDF).

September 24, 1986. Letter. 9 Page(s).
John Moore. Office of Pesticides & Toxic Substances.
Cancellation of Pesticide Products Containing Dicofol for Failure to Comply with the
May 29, 1986, Notice of Intent to Cancel. Rohm and Haas confidential business
information on pages 2-5 is not included.
Document (PDF) (596 KB PDF).

October 20, 1986. Memorandum. 5 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol - Request for Analyses. Quality Assurance Plan. Manufacturing process information
on page 2, and quality control procedure information on pages 3-4 are not included.
Document (PDF) (1539 KB PDF).

November 18, 1986. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
Mitigan Technical, EPA Reg. No. 11603-26. Additional Product Chemistry Data in
Response to PD4 and EPA Letter of 3/14/86 [Accession No. 264826, RCB No. 1435].
Quality control procedure information on pages 3-4 is not included.
Document (PDF) (573 KB PDF).

November 21, 1986. Memorandum. 5 Page(s).
Susan Hummel. Residue Chemistry Branch.
Dicofol - Revised Quality Assurance Plan. Manufacturing process and quality control
procedure information on pages 2-5 are not included.
Document (PDF) (1550 KB PDF).

November 24, 1986. Memorandum. 3 Page(s).
Rita Kumar. Insecticide Rodenticide Branch.
IRB/TSS Precautionary Labeling Review. 707-ENG. Kelthane Technical.
Inert ingredient information on pages 1 and 2, and product impurity
information on pages 1 and 3 are not included.
Document (PDF) (151 KB PDF).

November 25, 1986. Memorandum. 2 Page(s).
Rita Kumar. Insecticide Rodenticide Branch.
IRB/TSS Precautionary Labeling Review. 707-ENG. Kelthane Technical.
Product impurity information on page 1 is not included.
Document (PDF) (114 KB PDF).

December 15, 1986. Memorandum. 2 Page(s).
Rita Kumar. Insecticide Rodenticide Branch.
IRB/TSS Precautionary Labeling Review. 707-ENG. Kelthane Technical.
Product impurity information on page 1 is not included.
Document (PDF) (76 KB PDF).

February 17, 1987. Memorandum. 4 Page(s).
Susan Hummel. Residue Chemistry Branch.
EPA File Symbol 707-ENG. Rohm and Haas Kelthane Technical. Additional Product
Chemistry Data Supporting New Product Application (No Accession Number; RCB No. 1878).
Document (PDF) (164 KB PDF).

May 27, 1987. Memorandum. 21 Page(s).
Theodore Farber. Toxicology Branch.
Kelthane: Evaluation of a rat metabolism study of dicofol Tox review 005915.
Acc. No. 400420. Manufacturing process information on page 6 is not included.
Document (PDF) (990 KB PDF).

May 27, 1987. Memorandum. 64 Page(s).
Susan Hummel. Residue Chemistry Branch.
010501 - Dicofol. Rohm & Haas Response to Registration Standard. Metabolism,
Methodology, and Residue Data. EPA File Symbol 707-ENE [MRID Nos. 400420-01 to -31, RCB No. 1869].
Document (PDF) (3524 KB PDF).

June 01, 1987. Review. 33 Page(s).
Michael Slimak. Ecological Effects Branch.
Submission of Avian Reproduction and Aquatic Data in Response to Registration
Standard MRID 400420-55, -61, -59, -58, -57, -56, -60.
Document (PDF) (1638 KB PDF).

September 25, 1987. Memorandum. 4 Page(s).
Leung Cheng. Residue Chemistry Branch.
EPA Reg. No. 7001-259. Dicofol Registration Standard Response. Residue Study
Protocols for Succulent Beans and Hops. No MRID #. RCB No. 2579.
Document (PDF) (209 KB PDF).

October 19, 1987. Memorandum. 46 Page(s).
Susan Hummel. Residue Chemistry Branch.
010501 - Dicofol. Rohm and Haas Response to Registration Standard Residue Data
and Feeding Studies. EPA File Symbol 707-ENE. [MRID Nos. 400420-01 to -02
and -09 to -31, RCB No. 2578].
Document (PDF) (2950 KB PDF).

December 17, 1987. Review. 2 Page(s).
Richard Stevens. Ecological Effects Branch.
Review of Fish and Avian Reproduction Protocols.
Document (PDF) (91 KB PDF).

March 03, 1988. Memorandum. 7 Page(s).
Susan Hummel. Residue Chemistry Branch.
EPA Reg. No. 707-203. Rohm and Haas Kelthane Technical. Product Chemistry
Supporting Amendment to Reduce DDTr Impurities to 0.1% (MRID No. 405045-01;
RCB No. 3388). Inert ingredient information on page 5, and product impurity
info on page 6 not included.
Document (PDF) (456 KB PDF).

May 09, 1988. Memorandum. 5 Page(s).
Susan Hummel. Residue Chemistry Branch.
May 4, 1988 Meeting Regarding Dicofol Registration Standard Deficiencies and
S. Hummel Reviews of 5/27/87 and 10/27/87.
Document (PDF) (307 KB PDF).

July 06, 1988. Review. 4 Page(s).
James Akerman. Ecological Effects Branch.
Submission of Data. Review of response to Data Call-In Notice of September 29, 1987
Freshwater fish LC50 study. Sheepshead minnow acute toxicity study.
Acc. No. 400420-56, 400420-58.
Document (PDF) (200 KB PDF).

August 10, 1988. Memorandum. 2 Page(s).
Edward Zager. Residue Chemistry Branch.
EPA Reg. No. 707-203 Rohm and Haas Kelthane Technical Additional Product
Chemistry Data supporting Amendment to reduce DDTr impurities to 0.1%
[Supplement to MRID No. 405045-01, RCB No. 4116].
Document (PDF) (73 KB PDF).

February 27, 1989. Memorandum. 2 Page(s).
Francis Suhre. Dietary Exposure Branch.
Dicofol (010501) - time Extension request for Plant Metabolism Study on Green
Beans Rohm and Haas letter of 6/23/88 [No MRID No., RCB No. 4344].
Document (PDF) (72 KB PDF).

May 18, 1989. Memorandum. 3 Page(s).
Francis Suhre. Dietary Exposure Branch.
Mitigan Technical, EPA Reg. No. 11603-26 Additional Product Chemistry Data in
response to EPA letter of 1/14/87 [MRID Nos. 402972-01, DEB No. 2881].
Document (PDF) (149 KB PDF).

August 24, 1989. Review. 12 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Addendum to a Standard (Review of aerobic soil metabolism studies)
MRID 41094201, 41050701. Guideline 162-1.
Document (PDF) (580 KB PDF).

August 24, 1989. Review. 17 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Addendum to a Standard (Review of photodegradation in water studies)
MRID 40849702, 40849701. Guideline 161-2.
Document (PDF) (908 KB PDF).

September 05, 1989. Memorandum. 28 Page(s).
Marcia Van Gemert. Toxicology Branch II.
Dicofol (Kelthane): Review of One-Year Dietary Toxicity Study in Beagle Dogs.
Tox review 007482. MRID 409971-01.
Document (PDF) (1209 KB PDF).

November 17, 1989. Memorandum. 7 Page(s).
Marcia Van Gemert. Toxicology Branch II.
Dicofol : Review of a 4-Week Dermal Toxicity Study in Rabbits Tox review 007616.
MRID 410770-01. Guideline 82-2.
Document (PDF) (887 KB PDF).

November 27, 1989. Memorandum. 3 Page(s).
Andrew Rathman. Dietary Exposure Branch.
Dicofol. Request for Residue Field Trials and Brewing Studies on Tea.
Document (PDF) (170 KB PDF).

May 07, 1990. Memorandum. 15 Page(s).
Marcia Van Gemert. Toxicology Branch II.
Dicofol: Review of a chronic feeding/oncogenicity study in rats. Tox review 007903.
MRID 411500-01. 83-1a; Chronic rodent. 83-2a; Onco-rodent.
Document (PDF) (981 KB PDF).

June 14, 1990. Review. 3 Page(s).
James Akerman. Ecological Effects Branch.
Submission of Oyster Shell Growth Study MRID 410267-01. 72-3b.
Document (PDF) (124 KB PDF).

June 15, 1990. Memorandum. 2 Page(s).
James Akerman. Ecological Effects Branch.
Review of Mallard Reproduction Study with Dicofol Reg# 000707-00107
MRID No: 412313-01. 71-4b.
Document (PDF) (91 KB PDF).

July 25, 1990. Memorandum. 99 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
1.Environmental-fate assessment for dicofol. 2.Copy of the label for Technical
Kelthane. 3.The environmental-fate data-requirements for...4.An appendix with
structures of dicofol and its degradates 5.Copies of the DERs on Dicofol
6.Summary of Literature.
Document (PDF) (4390 KB PDF).

May 27, 1991. Memorandum. 3 Page(s).
James Akerman. Ecological Effects Branch.
Review of Fish Acute Toxicity Studies Reg# 000707-00203
MRID 416954-02, 416954-01. 72-3a, 72-1.
Document (PDF) (117 KB PDF).

June 14, 1991. Review. 31 Page(s).
Acurex Corporation.
Dicofol Task 3 Reregistration Standard Update- Product Chemistry. Manufacturing
process information on pages 5 and 31 is not included.
Document (PDF) (1552 KB PDF).

July 26, 1991. Memorandum. 57 Page(s).
Marcia Van Gemert. Toxicology Branch II.
Dicofol-Evaluation of Developmental Toxicity Studies in Rat and Rabbit, and a 2-
Generation Reproduction Study in Rats Tox review 008476. MRID Nos. 400420-46,
400420-47, 418066-01 Guidelines 83-3a, 83-3b, 83-4.
Document (PDF) (2985 KB PDF).

September 17, 1991. Review. 8 Page(s).
Douglas Urban. Ecological Effects Branch.
Review rebuttal to EEB review of rainbow trout acute study MRID 419857-01,
416954-01, 419857-01 (supplemental).
Document (PDF) (431 KB PDF).

September 24, 1991. Review. 3 Page(s).
Douglas Urban. Ecological Effects Branch.
Review data submitted to upgrade earlier studies MRID 420035-01, -02, -03, 400420-55,
400420-57, 400420-60. 71-4a, 72-2a, 72-3c.
Document (PDF) (135 KB PDF).

September 24, 1991. Review. 7 Page(s).
Allen Vaughan. Ecological Effects Branch.
Review reproduction study on kestrels MRID 419340-01. 71-4b.
Document (PDF) (353 KB PDF).

October 01, 1991. Memorandum. 31 Page(s).
Marcia Van Gemert. Toxicology Branch II.
Dicofol technical. Mutagenicity data review Tox review 008622. MRID Nos. 400420-48,
400420-49, 400420-50 400420-51, 400420-52. Guidelines 84-2a, 84-2b, 84-2c; mutagenicity.
Document (PDF) (1717 KB PDF).

June 24, 1992. Memorandum. 12 Page(s).
Whang Phang. Toxicology Branch II.
Carcinogenicity Peer Review of Dicofol.
Document (PDF) (652 KB PDF).

February 03, 1993. Review. 4 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Dicofol. Rohm and Haas. Submission of Second Supplemental Report on Rainbow
Trout Early Life-Stage Study.
Document (PDF) (298 KB PDF).

February 12, 1993. Memorandum. 2 Page(s).
A. R. Rathman. Chemistry Branch II.
Reregistration of Dicofol. Rohm and Haas Product Chemistry "Final Report - Series
63 Addendum". Case 818577; Chemical 10501. MRID 425148-01. CBRS 11222.
Action: 627 Generic Data Submission.
Document (PDF) (93 KB PDF).

July 29, 1993. Memorandum. 32 Pages.
Whang Phang. Toxicology Branch II.
Dicofol: Review of an acute neurotoxicity study in rats. DP Barcode: D187705.
MRID No. 426333-03. TXR No. 010445. Pages 11-32 removed, registration data.
Document (PDF) (412 KB PDF).

August 19, 1994. Memorandum. 59 Page(s).
Stephen Funk. Chemistry Branch II.
Dicofol (List A, Case 0021, Chemical 010501). Product Chemistry Chapter and
Residue Chemistry Chapter for the Reregistration Eligibility Decision Document.
DP Barcode D100110, CBRS No. 13185.
Document (PDF) (3311 KB PDF).

October 06, 1994. Memorandum. 38 Pages.
Whang Phang. Toxicology Branch II.
Dicofol: Review of a subchronic neurotoxicity in rats. MRID No. 429714-01.
DP Barcode D196309. Tox review No. 011268. Pages 12-38 removed, registration data.
Document (PDF) (450 KB PDF).

October 25, 1995. Memorandum. 55 Page(s).
Stephen Funk. Chemistry Branch II.
Dicofol (List A, Case 0021, Chemical 010501). Product Chemistry Data Update and
Residue Chemistry Chapter Update for the Reregistration Eligibility Decision Document.
DP Barcode D218284, CBRS No. 16001.
Document (PDF) (3498 KB PDF).

December 18, 1995. Memorandum. 20 Page(s).
Whang Phang. Toxicology Branch II.
Dicofol: Toxicology chapter of the RED for Dicofol.
Document (PDF) (1103 KB PDF).

June 03, 1998. Memorandum. 5 Pages.
Tim Leighton. Chemistry and Exposure Branch 2.
REVIEW OF DICOFOL OCCUPATIONAL AND RESIDENTIAL EXPOSURE
ASSESSMENT RED REBUTTAL (MRID No. 445528-01; Reregistration Case No. 0021;
Chemical No. 010501) DP Barcode D246346.
Document (PDF) (209 KB PDF).

September 30, 1998. Memorandum. 11 Pages.
Sheila Piper. Chemistry & Exposure Branch 1.
Dicofol (010501). Reregistration Case No 0021. Revision: Acute Dietary Monte Carlo
for Dicofol Using Complete Distributions of Field Trial Residues. MRID 44636501.
DP Barcode D248601.
Document (PDF) (282 KB PDF).

June 22, 2006. Memorandum. 37 Pages.
Guruva B. Reddy. Registration Action Branch I / HED.
Dicofol: Review of Special One-generation Reproduction Study - Rat
(MRIDs 44253801, 44559901 and 44624301). DP Barcode No. D325924. TXR#: 0053453.
Document (PDF) (1235 KB PDF).

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