Agenda

The Asbestos Mechanisms of Toxicity Workshop was held on June 12-13, 2003.

Time	Session Title	Speaker(s)
08:00 - 08:30	Introduction	Anna Treinies, EPA OSWER Dr. Lee Hofmann, EPA OSWER Science Advisor Kim Fletcher, Facilitator Dr. Kevin Driscoll, Workshop Chair
Panel 1	Exposure and Dose Response Relationship	Chair: Dr. Kevin Driscoll
08:30 - 09:15	Influence of Fiber Type, Size, and Number in Human Disease: Conclusions from Fiber Burden Analysis	Dr. Andrew Churg, University of British Columbia
09:15 - 10:00	Experience with Occupational and Environmental Asbestos Exposure	Dr. James Lockey, University of Cincinnati
10:00 - 10:15	BREAK
10:15 - 11:00	Influence of Fiber Type, Size and Exposure in the Cancer and Non-Cancer Response to Asbestos Fibers (Animal Studies)	Dr. Eugene McConnell, ToxPath, Inc.
11:00 - 12:00	Panel Discussion
12:00 - 1:00	LUNCH
Panel 2	Mechanisms of Fiber-Inducing Lung and Pleural Disease	Chair: Dr. Kevin Driscoll
1:00 - 1:45	Mechanisms of Pulmonary Fibrosis	Dr. Arnold Brody, Tulane University
1:45- 2:30	Mechanisms of Fiber-Induced Lung Disease	Dr. Vincent Castranova, NIOSH
2:30 - 2:45	BREAK
2:45 - 3:30	Molecular Pathogenesis of Malignant Mesothelioma	Dr. Agnes Kane, Brown University
3:30 - 4:15	Fiber Durability and Biopersistence - Assessment and Role in Asbestos Toxicology	Dr. Charles Hobbs, Lovelace Respiratory Research Institute (LRRI)
4:15 - 5:00	Panel Discussion
5:00	ADJOURN

Time	Session Title	Speaker(s)
Panel 3	Molecular and Biochemical Mechanisms of Asbestos Fiber Toxicity	Chair: Dr. Kevin Driscoll
08:00 - 08:45	Asbestos-Induced Cell Activation and Proliferation	Dr. Brooke Mossman, University of Vermont
08:45 - 09:30	Genetic Effects of Asbestos Fibers	Dr. Tom K. Hei, Columbia University
09:30 - 09:45	BREAK
09:45 - 10:30	Influence of Chemical/Physical Properties of Asbestos Fiber on Biological Activity	Dr. Bice Fubini, University of Torino
10:30 - 11:30	Panel Discussion
11:30 - 12:30	Plenary Panel Discussion / Closing Remarks