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Index of Cleared Science Reviews for Tetramethrin (Pc Code 069003)
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February 06, 1981. Memorandum. 10 Page(s).
Cheryl A. Peterson. Insecticide Rodenticide Branch.
EPA File Symbol: 39398-RH Pesguard NS 4/1 WB. Pages 8-10 removed, draft label.
Tox review 000290.
Document (PDF) (464 KB PDF).
February 13, 1981. Memorandum. 3 Page(s).
B. T. Backus. Insecticide Rodenticide Branch.
EPA File Symbol 4822-RIN. Raid Indoor Fogger II. Caswell #s 844, 652B, 715, 670, 613.
Document (PDF) (166 KB PDF).
March 12, 1981. Efficacy Review. 6 Page(s).
R. S. Van Denburgh. Insecticide Rodenticide Branch.
File No. 4822-RIN. Raid Indoor Fogger II. Registration. Inert ingredient and product
ingredient source information on pages 1-2 are not included.
Document (PDF) (255 KB PDF).
January 25, 1982. Memorandum. 8 Page(s).
B. T. Backus. Insecticide Rodenticide Branch.
EPA File Symbol 1021-RUOE. Evercide Intermediate 2244. Caswell Nos. 844,
77A. Inert ingredient information on pages 1, 2, 4 not included. Pages 5-8 removed, draft label.
Tox review 001413.
Document (PDF) (328 KB PDF).
March 19, 1982. Review. 2 Page(s).
R. S. Van Denburgh. Insecticide Rodenticide Branch.
Raid Indoor Fogger II. Registration. Product ingredient source information on page 1 not included.
Document (PDF) (78 KB PDF).
June 28, 1982. Memorandum. 2 Pages.
B. T. Backus. Insecticide Rodenticide Branch.
EPA Reg. No. 10308-1 NEOPYNAMIN TECHNICAL GRADE Caswell #844.
Document (PDF) (94 KB PDF).
April 11, 1983. Memorandum. 19 Page(s).
John Doherty. Toxicology Branch.
EPA Reg.No. 10308-1. Tetramehtrin Review of rat chronic feeding/oncogenesis
studies (2 studies), mouse range-finding study (13 weeks) and dog subchronic feeding
study (26 weeks) with... Neopynamin. ID of testes as oncogenic target... Tox review 002657.
Document (PDF) (1111 KB PDF).
February 25, 1984. Memorandum. 27 Page(s).
John Doherty. Toxicology Branch.
EPA Reg.No. 10308-1. Review of rat fertility study and rat and rabbit teratology
studies with tetramethrin (neopynamin) and of additional pathology information regarding...
testicular ademonas in the rat... and cancer risk assessment Tox review 003660.
Document (PDF) (1347 KB PDF).
August 12, 1985. Memorandum. 9 Page(s).
Reto Engler. Toxicology Branch.
Preliminary Risk Assessment of Tetramethrin - Based on Sprague-Dawley (1974-1981)
and Long Evans Rat (1981) Studies Registration No. 10308-1.
Document (PDF) (346 KB PDF).
October 31, 1985. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch.
Tetramethrin-Addendums to Pathology of the rat testis report exposure assessment,
risk assessment and current status summary of studies with technical grade tetramethrin.
Document (PDF) (384 KB PDF).
July 15, 1986. Memorandum. 18 Pages.
John Doherty. Toxicology Branch.
EPA Reg. No. 10308-1 - Tetramethrin: Review of mouse oncogenicity study. Return
of study and request for additional information to complete review. TOX CHEM No. 844.
TOX Project No. 1753. Record No. 173893. Accession Nos. 262778 thru 262788.
Document (PDF) (775 KB PDF).
September 30, 1986. Memorandum. 11 Page(s).
John Doherty. Toxicology Branch, Hazard Evaluation Div.
EPA Reg. No. 10308-1. Tetramethrin Partial Company Response to Toxiciology
Branch Request for Revised Histopathology Tables and Individual Animal Pathology
Data Sheets. Assignment of Core... for the 1981 Rat Special Oncogenicity Study.
Tox review 005533.
Document (PDF) (746 KB PDF).
March 20, 1987. Memorandum. 5 Pages.
William Dykstra. Toxicology Branch.
Tetramethrin - EPA Registration No. 10308-1 - Mouse Oncogenicity Study Issues
Relating to Reformatted Pathology Tables. Caswell No. 844. Record No. 187797.
Project No. 7-0360. Accession Nos. 262776 to 262788.
Document (PDF) (332 KB PDF).
April 30, 1987. Memorandum. 23 Page(s).
William Dykstra. Toxicology Branch, Hazard Evaluation Div.
Tetramethrin; EPA Reg. No. 10308-1; Addendum to Pathology Report.
Pages 4-23 removed, registration data. MRID 143555. Tox review 005899.
Document (PDF) (163 KB PDF).
October 20, 1987. Memorandum. 8 Page(s).
William Dykstra. Toxicology Branch.
Tetramethrin (Neopynamin) - EPA Registration No. 10308-1 Mutagenicity Studies and
Acute Dermal Toxicity Study. MRID Nos 402757-01 402758-01, 402759-01, 402760-01,
402861-01, 402862-01, 402804-01. Tox review 006386.
Document (PDF) (439 KB PDF).
October 20, 1987. Memorandum. 9 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin (Neopynamin) - EPA Registration No. 10308-1 - Mutagenicity Stidies
and Acute Dermal Toxicity Study. MRID Nos. 402757-01, 402758-01, 402759-01,
402760-01, 402861-01, 402862-01, 402804-01. Tox Review No. 006386.
Document (PDF) (471 KB PDF).
May 24, 1988. Data Eval. Rec. 20 Page(s).
Edwin Budd. Toxicology Branch.
Chronic Toxicity/Oncogenicity Feeding Study--Mice Accession 262778-262788 and 402763-01.
Document (PDF) (761 KB PDF).
June 17, 1988. Memorandum. 22 Page(s).
William Dykstra. Toxicology Branch.
EPA Registration No. 10308-1 - Tetramethrin (Neopynamin) - Combined Chronic
Toxicity and Oncogenicity Study in Mice Acc. 262778, -88, 402763-01, 402804-00, -01.
Tox review 006755.
Document (PDF) (959 KB PDF).
July 11, 1988. Memorandum. 13 Page(s).
William Dykstra. Toxicology Branch, Hazard Evaluation Div.
Tetramethrin, EPA Reg. No. 10308-1; Addendum To: Cancer risk Assessment for
Neopynamin (Dated September 8, 1982 and signed July 21, 1984) Acc. 248341 Tox review 007655.
Document (PDF) (400 KB PDF).
July 22, 1988. Memorandum. 23 Page(s).
William Dykstra. Toxicology Branch, Hazard Evaluation Div.
Neopynamin (Tetramethrin). Submission of Toxicity Data to Address Data Gaps
Identified in Memorandum of 10/31/85 by J. Doherty. Acc. Nos. 262776 thru 262788
(except 262779) Tox review 006786.
Document (PDF) (1230 KB PDF).
October 20, 1988. Memorandum. 9 Page(s).
Bernice Fisher. Science Analysis & Coordination Branch.
Tetramethrin (Neopynamin) - Qualitative Risk Assessment, Two Year Dietary Rat
Studies - Charles River CD (1974 and 1981) and Long Evans (1981) Tox review 006950.
Document (PDF) (338 KB PDF).
November 03, 1988. Memorandum. 26 Page(s).
William Dykstra. Toxicology Branch.
Peer Review of Tetramethrin.
Document (PDF) (1094 KB PDF).
June 30, 1989. Memorandum. 10 Page(s).
William Dykstra. Review Section I Health Effects Division.
Tetramethrin (Neopynamin). EPA Reg. No. 10308-1. Two-Generation Rat
Reproduction Study with Neopynamin Forte and UDS Mutagenicity Assay with Neopynamin.
MRID 407778-01, 407784-01. Tox review 007306.
Document (PDF) (497 KB PDF).
July 31, 1989. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
Tetramethrin - Composition of Technical Tetramethrin Used in Toxicology Studies.
Document (PDF) (163 KB PDF).
September 20, 1989. Memorandum. 9 Page(s).
Edwin Budd. Toxicology Branch I.
Addendum to Peer Review Document for Tetramethrin. Pages 3-9 removed, registrant data.
Tox review 007656.
Document (PDF) (116 KB PDF).
November 02, 1989. Memorandum. 3 Pages.
William Dykstra. Toxicology Branch I.
Tetramethrin (Neo-Pynamin) - EPA Registration No. 10308-1 - Waiver Request for
Oncogenicity and Reproduction for Reregistration. Project No.: 9-2137. Caswell No.: 844.
Record No.: 251, 523. MRID Nos.: 114366, 143556.
Document (PDF) (123 KB PDF).
December 11, 1989. Memorandum. 14 Page(s).
George Ghali. Science Analysis & Coordination Branch.
Peer Review of Tetramethrin.
Document (PDF) (719 KB PDF).
May 25, 1990. Response. 28 Page(s).
Reregistration Branch..
Volume 1: Phase 3 Chemical Response Worksheet MRID No. 921810-00.
Product impurities information removed from page 4.
Document (PDF) (3408 KB PDF).
February 06, 1991. DER. 4 Page(s).
Allen Vaughan. Ecological Effects Branch.
Honey bee acute contact LD50. MRID No. 416096-13.
Document (PDF) (188 KB PDF).
February 20, 1991. DER. 11 Page(s).
Michael Whitten. Ecological Effects Branch.
Avian Dietary LC50 Test. Species Tested: Bobwhite quail (Colinus virginianus).
MRID No. 416096-05. Registration Data information removed from pages 6-11.
Document (PDF) (321 KB PDF).
February 20, 1991. DER. 5 Page(s).
Michael Whitten. Ecological Effects Branch.
Avian Single Dose Oral LD50 Test. Species Tested: Bobwhite quail (Colinus
virginianus). MRID No. 416096-04. Registration Data information removed from page 5.
Document (PDF) (266 KB PDF).
February 22, 1991. DER. 8 Page(s).
Louis Rifici. Ecological Effects Branch.
Freshwater Fish Acute Flow-Through Toxicity Test. Species Tested: Oncorhynchus
mykiss. MRID No. 416096-08. Registration Data information removed from pages 6-8.
Document (PDF) (316 KB PDF).
February 22, 1991. DER. 9 Page(s).
Louis Rifici. Ecological Effects Branch.
Freshwater Fish Acute Flow-Through Toxicitiy Test. Species Tested: Lepomis
macrochirus. MRID No. 416096-07. Registration Data information removed from pages 7-9.
Document (PDF) (358 KB PDF).
February 22, 1991. DER. 9 Page(s).
Louis Rifici. Ecological Effects Branch.
Freshwater Invertebrate Acte Flow-Through Toxicity Test. Species Tested: Dahnia
magna. MRID No. 416096-09. Registration Data information removed from pages 7-9.
Document (PDF) (403 KB PDF).
November 07, 1991. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Additional Supplementary Data on Purity of Technical Tetramethrin
Used in Rat Teratology Study (#IT-01-0076; June 14, 1980). MRID No. 420144-02.
Tox Review No. 008795.
Document (PDF) (54 KB PDF).
January 22, 1992. DER. 16 Page(s).
Pia Lindstrom. Toxicology Branch I.
Developmental Toxicity in Rabbits. (An Oral Teratology Stud of Neo-Pynamin in the Rabbit).
MRID No. 419950-05. Tox Review No. 010285.
Document (PDF) (659 KB PDF).
January 23, 1992. DER. 20 Page(s).
John Liccione. Toxicology Branch I.
Three-Month Inhalation Toxicity Study of Tetramethrin in Rats. Registration data removed
from page 5. MRID No. 420121-01. Tox Review 010285.
Document (PDF) (938 KB PDF).
January 29, 1992. DER. 17 Page(s).
Carrie Rabe. Toxicology Branch I.
Subchronic Inhalation Toxicity in Rats. - Three-month Inhalation Toxicity Study of
Neo-Pynamin in Rats (Determination of the No Observed Effect Level). MRID No. 419950-03.
Document (PDF) (902 KB PDF).
January 30, 1992. DER. 14 Page(s).
Regina Mastrangelo. Toxicology Branch I.
21-Day Dermal Toxicity Study in Rats with Neo-Pynamin. MRID No. 419950-04.
Document (PDF) (650 KB PDF).
March 25, 1992. Memorandum. 1 Page(s).
Doug Urban. Ecological Effects Branch.
Tetramethrin List B Reregistration; Ecological Effects Requirements.
MRID Nos. 416096-04, 05, 06, 07, 08, 09, 13.
Document (PDF) (72 KB PDF).
May 04, 1992. DER. 5 Page(s).
Michael Whitten. Ecological Effects Branch.
Avian Dietary LC50 Test. Species Tested: Mallard (Anas platyrhynchos).
MRID No. 416096-06.
Document (PDF) (283 KB PDF).
July 21, 1992. DER. 5 Page(s).
William Dykstra. Toxicology Branch I.
Additional Six-Month Subchronic Toxicity Study of Neopynamin Forte in Rats.
MRID No. 421464-02. End of Sept. 1999.
Document (PDF) (257 KB PDF).
July 22, 1992. DER. 6 Page(s).
William Dykstra. Toxicology Branch I.
Acute and Subacute Inhalation Toxicity Studies of Neo-Pynamin Forte in Rats.
MRID No. 421464-01. Registration Data information removed from page 6.
Document (PDF) (319 KB PDF).
July 22, 1992. DER. 6 Page(s).
William Dykstra. Toxicology Branch I.
Six-Month Subchronic Toxicity Study of Neopynamin Forte in Rats.
MRID No. 421464-03.
Document (PDF) (365 KB PDF).
August 01, 1992. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Bridging Data with Neo-Pynamin Forte Submitted in Support of Neo-
Pynamin (Tetramethrin) Guideline Study 83-4 for Reregistraion. MRID Nos. 421464-01,
-06; & 421615-01, -02. Tox Review No. 009640.
Document (PDF) (168 KB PDF).
November 24, 1992. Memorandum. 13 Pages.
William Dykstra. Review Section I Health Effects Division.
Tetramethrin; One Year Chronic Toxicity Dog Study; ID# 069003-010308;
Miscellaneous Data Reregistration Submitted for Reregistration.
DP Barcode No.: D174421. Caswell No.: 844. Project No.: 2-1371.
Submission No.: S411530. MRID No.: 421893-01. TXR 009836.
Document (PDF) (335 KB PDF).
November 25, 1992. Memorandum. 10 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Oral Teratology Study in RAts with Technical Tetramethrin; Guideline
Study 83-1; ID # 069003-010308. MRID No. 421892-01, -02. Tox Review No. 009842.
Document (PDF) (507 KB PDF).
May 05, 1993. Memorandum. 37 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Rat General Metabolism Studies with c14-Cis- Tetramethrin and C14-
Trans-Tetramethrin; ID #069003-010308; Guideline Requirement 85-1.
MRID No. 424489-01 & 02. Tox Review No. 010235.
Document (PDF) (942 KB PDF).
May 27, 1993. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Miscellaneous Data; ID # 069003-010308; Reregistration Action.
MRID Nos. 419950-03, 04, 05; 420121-01. Tox Review No. 010285.
Document (PDF) (168 KB PDF).
September 13, 1993. Memorandum. 8 Page(s).
Pamela Hurley. Toxicology Branch I.
069003. Tetramethrin Developmental Toxicity Study in Rabbits -Review of Historical
Control Data and Range-Finding Study. MRID Nos. 428789-01 & 02. Tox Review No. 016557.
Document (PDF) (410 KB PDF).
March 08, 1994. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch I.
Tetramethrin; Supplemental Data to Subchronic Inhalation Studies
(Guideline Requirement 82-4); ID # 069003-010308; Reregistration Case #: 2660.
MRID Nos. 429177-01, -02.
Document (PDF) (96 KB PDF).
September 19, 2002. Efficacy Review. 2 Page(s).
Kevin Sweeney. Insecticides Branch.
EPA Reg. No: 1021-1667 and 7056-185 DP #: D283211 Sites indoor and outdoor
residential Pests: many residential pests MRID 45666601.
Document (PDF) (75 KB PDF).
June 16, 2003. Efficacy Review. 2 Page(s).
Kevin Sweeney. Insecticides Branch.
EPA Reg. No: 1021-1667 DP #: D287637 Sites: outdoor residential Pests: many
residential pests this is for adult mosquitoes MRID 45831901.
Document (PDF) (144 KB PDF).
June 27, 2004. Efficacy Review. 2 Page(s).
Kevin Sweeney. Insecticides Branch.
EPA Reg. No: 1021-1667 DP D298912 Sites: outdoor residential Pests: many
residential pests this is for adult mosquitoes MRID 46079801.
Document (PDF) (93 KB PDF).
June 28, 2004. Efficacy Review. 2 Page(s).
Kevin Sweeney. Insecticides Branch.
EPA Reg. No: 1021-1667 and 1021-1588 DP: 299482 and 304660 Sites: outdoor
residential Pests: many residential pests this is for adult mosquitoes MRID 46183201.
Document (PDF) (60 KB PDF).
March 03, 2009. Memorandum. 105 Pages.
Jessica Ryman. Risk Assessment Branch IV.
Tetramethrin/Neo-pynamin; Updated Tox DERs. DP Barcodes: D292301, D234962, D229247,
D229511. Decision Nos.: 329938, 315642. Case No.: 2660. CAS No.: 7696-12-0.
TXR No: 0054713. MRIDs 44222801, 44083501, and 44096001.
Document (PDF) (5150 KB PDF).