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Index of Cleared Science Reviews Omadine-zinc (Pc Code 088002)
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November 19, 1968. Tox Review. 14 Page(s).
Paul D. Baron. Toxicology Branch.
Chemical Name: Zinc 2-pyridine thiol 1-oxide. Use: Cosmetic
Preservation Cutting Fluid Systems- bacteriocide. Tox review 003932.
Document (PDF) (878 KB PDF).
September 13, 1978. Tox Review. 35 Page(s).
William Dykstra. Toxicology Branch.
Zinc Omadine Industrial Microbiostat EPA Registration # 1258-840
Caswell 4923 (Zinc 2-pyridinethiol-1-oxide). Tox review 003933.
Document (PDF) (3958 KB PDF).
March 12, 1985. Memorandum. 28 Page(s).
Carlos A. Rodriguez. Toxicology Branch I.
Omadine MDS (Sodium or Zinc)-18-month Skin Painting Carcinogenicity
Study in CD-1 Mice. EPA Reg. No. 1258-840; 1258-842. Pages 19-28
removed, registration data. MRID Nos. 254132-254138.
Tox review 004398.
Document (PDF) (728 KB PDF).
May 01, 1986. Memorandum. 6 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 53707-R Supercide Acute inhalation, eye irritation,
primary dermal irritation Acc 260075 Tox review 006177.
Document (PDF) (257 KB PDF).
May 09, 1991. Memorandum. 6 Page(s).
John Whalan. Toxicology Branch.
New Use Patterns for Zinc Omadine. EPA ID# 001258-00840.
Document (PDF) (293 KB PDF).
May 10, 1991. Memorandum. 5 Page(s).
John Whalan. Toxicology Branch.
New Use Pattern for Zinc Omadine. EPA ID# 001258-00840.
Document (PDF) (271 KB PDF).
September 03, 1991. Memorandum. 4 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine; Review of an Acute Inhalation Toxicity Study.
EPA ID# 1258-840 MRID 417764-01 Tox review 008536.
Document (PDF) (217 KB PDF).
February 24, 1992. Memorandum. 3 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine; Review of a Primary Eye Irritation Study in Rabbits
Submitted as Sec. 6 (a)(2) Data. MRID No. 421546-01
Tox review 009304.
Document (PDF) (176 KB PDF).
June 22, 1992. Memorandum. 6 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine; Request for Waiver of Six Toxicology Studies.
EPA ID# 088002-001258.
Document (PDF) (285 KB PDF).
April 01, 1993. Memorandum. 2 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Preliminary Reporting of Adverse Developmental Toxicity
Findings in Compliance with FIFRA Sec. 6 (a)(2).
Document (PDF) (109 KB PDF).
May 27, 1993. Memorandum. 31 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Mutagenicity Study. EPA ID# 088002-001258
MRID 419065-01, 02, 03 Tox review 010288.
Document (PDF) (1446 KB PDF).
June 22, 1993. Memorandum. 3 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Primary Dermal Irritation Study in Rabbits.
EPA ID# 088002-001258 MRID 421467-04 Tox review 010359.
Document (PDF) (125 KB PDF).
June 22, 1993. Memorandum. 3 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of an Acute Dermal Toxicity Study in Rabbits.
EPA ID# 088002-001258 MRID 421467-01 Tox review 010356.
Document (PDF) (158 KB PDF).
June 22, 1993. Memorandum. 4 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Primary Eye Irritation Study in Rabbits.
EPA ID# 088002-001258 MRID 421467-02 Tox review 010358.
Document (PDF) (218 KB PDF).
June 22, 1993. Memorandum. 4 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of an Acute Inhalation Toxicity Study in Rats.
EPA ID# 088002-001258 MRID 421467-03 Tox review 010357.
Document (PDF) (242 KB PDF).
June 22, 1993. Memorandum. 8 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Dermal Sensitization Study in Guinea Pigs.
EPA ID# 088002-001258 MRID 421467-05. Pages 6-8 removed,
registrant data. Tox review 010360.
Document (PDF) (205 KB PDF).
September 23, 1994. Memorandum. 2 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Purity Data for Three Mutagenicity Studies. EPA ID#
088002-001258 Manufacturing process info. and inert ingredient info. on
page 2 is not included.
Document (PDF) (134 KB PDF).
May 16, 1995. Memorandum. 8 Page(s).
John E. Whalan. Toxicology Branch I.
Zinc Omadine: Purity Data for Three Mutagenicity Studies. Inert ingredient
info on pages 2, 3, 7 and 8 not included. Pages 4-5 removed,
manufacturing data. Page 6 removed, inert ingredient information.
MRIDs 419065-01, 02, 03. Tox review 011549.
Document (PDF) (349 KB PDF).
August 24, 1995. Memorandum. 5 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Dermal Sensitization Study in Guinea Pigs.
EPA ID# 088002-001258. MRID No. 433720-01 Tox review 011654.
Document (PDF) (316 KB PDF).
August 29, 1996. DER. 20 Page(s).
John Whalan. Toxicology Branch.
Developmental Toxicity Study in Rats with Zinc Omadine; (83-3a).
MRID Nos. 428279-04 & 428279-08.
Document (PDF) (984 KB PDF).
August 29, 1996. DER. 6 Page(s).
John Whalan. Toxicology Branch.
Single Dose Oral Toxicity in Rats/LD 50 in Rats; Acute Oral (Gavage) -
Rat (81-1). MRID No. 428279-01.
Document (PDF) (289 KB PDF).
August 29, 1996. Memorandum. 11 Page(s).
John Whalan. Toxicology Branch.
Zinc Omadine: Review of a Dermal Sensitization Study in Guinea Pigs.
EPA ID# 088002-001258. MRID No. 43950201. Inert ingredient info on
pages 2, 4 not included. Tox review 012034.
Document (PDF) (964 KB PDF).
May 19, 1997. DER. 9 Page(s).
Regina Hirsch. Ecological Effects Branch.
Acute LC50 Test With An Estuarine/Marine Shrimp; 72-3(C).
MRID No. 438646-07.
Document (PDF) (858 KB PDF).
May 23, 1997. Memorandum. 149 Page(s).
Dan Rieder. Ecological Effects Branch.
Reg./File #: 001258-REEG Zinc Omadine Review [aquatic organism,
avian] data for antifoulant use. MRID 438646-04 thru 13, -21 thru 27.
(continued) Pages 30, 39, 59, 90 and 131-132 removed, registrant data.
Document (PDF) (11047 KB PDF).
June 26, 1998. DER. 1 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-2 - Acute EC50 Test With Freshwater Invertebrate.
MRID No. 438646-19.
Document (PDF) (55 KB PDF).
June 26, 1998. DER. 1 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-3 - Acute LC50 Test With An Estuarine/Marine Fish.
MRID No. 438646-17.
Document (PDF) (57 KB PDF).
June 26, 1998. DER. 2 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-1 - Acute LC50 Test With A Coldwater Fish. MRID No. 438646-16.
Document (PDF) (112 KB PDF).
June 26, 1998. DER. 2 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-1 - Acute LC50 Test With A Warmwater Fish. MRID No. 438646-18.
Document (PDF) (87 KB PDF).
June 26, 1998. DER. 2 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-3 - Acute LC50 Test With An Estuarine/Marine Shrimp.
MRID No. 438646-20.
Document (PDF) (97 KB PDF).
June 26, 1998. DER. 6 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-3 - Acute EC50 Test With An Estuarine/Marine Mollusk; Shell
Deposition Study. MRID No. 438646-15.
Document (PDF) (244 KB PDF).
July 08, 1998. Memorandum. 5 Page(s).
Akiva D. Abramovitch. Risk Assessment & Science Support Branch.
Zinc Omadine Environmental Fate Science Review. MRID: 438646-02,
440115-01, 440104-01, 02, 03, 43866-03.
Document (PDF) (319 KB PDF).
August 14, 1998. Review. 6 Page(s).
Anna Skapars. Efficacy & Science Support Branch.
Product Chemistry Review; Antimicrobials Div.; DP Barcode D247618;
Reg No. 2693-188. Inert Ingredient info removed from page 1.
Document (PDF) (370 KB PDF).
September 25, 1998. DER. 1 Page(s).
Mark Mossler. Risk Assessment & Science Support Branch.
72-1 - Acute LC50 Test With A Warmwater Fish. MRID No. 445912-04.
Document (PDF) (54 KB PDF).
March 02, 1999. Memorandum. 36 Page(s).
Wallace Powell. Efficacy & Science Support Branch.
Intersmooth 365 Ecoflex SPC Antifouling, Product No 2693-RII [Courtaulds
Coatings submitted studies for acute toxicity; primary eye irritation to
support waiver doesn't have MRID] Inert ingredient info on pages 2-4, 25,
29 deleted. MRIDs 44587202 thru -08.
Document (PDF) (2605 KB PDF).
March 17, 1999. DER. 8 Page(s).
Kathryn Montague. Risk Assessment & Science Support Branch.
Aquatic Invertebrate Life Cycle Test; Guideline 72-4.
MRID No. 445354-01.
Document (PDF) (624 KB PDF).
July 21, 1999. Memorandum. 2 Page(s).
Nancy Whyte. Efficacy & Science Support Branch.
Product Chemistry Review of: Intersmooth 360 Ecoflex SPC Antifouling
BEA 368 Dark Brown. Reg. No. 2693-RIT. Inert ingredient info on pages
1-2 not included.
Document (PDF) (103 KB PDF).
July 28, 1999. Memorandum. 2 Page(s).
Nancy Whyte. Efficacy & Science Support Branch.
Product Chemistry Review of: Intersmooth 360 Ecoflex SPC Antifouling
BEA 368 Dark Brown. Reg. No. 2693-RIT. Inert ingredient info on pages
1-2 not included.
Document (PDF) (99 KB PDF).
November 30, 1999. Memorandum. 5 Page(s).
Ian Blackwell. Product Science Branch AD.
Acute Toxicity Review for EPA Reg. No.: 2693-RII [eye irritation].
MRID 44877102.
Document (PDF) (191 KB PDF).
December 01, 1999. Memorandum. 20 Page(s).
Chris Jiang. Risk Assessment & Science Support Branch.
Review of the Leach Rate of Zinc Omadine from Ecoloflex Paint,
Reference Code BEA369/G044, in Synthetic Seawater (3.80%).
Pages 7-19 removed, registration data. MRID 44877103.
Document (PDF) (288 KB PDF).
December 01, 1999. Memorandum. 20 Page(s).
Chris Jiang. Risk Assessment & Science Support Branch.
Review of the Leach Rate of Zinc Omadine from Ecoloflex Paint.
Reference Code BEA468/G580, in Synthetic Seawater (3.80%).
Pages 7-19 removed, registration data. MRID 44877104.
Document (PDF) (288 KB PDF).
December 01, 1999. Memorandum. 21 Page(s).
Chris Jiang. Risk Assessment & Science Support Branch.
EPA Reg. No. 2693-RII. Review of the Leach Rate of Zinc Omadine from
Ecoloflex Paint, Reference Code BEA369/G044, in Synthetic Seawater
(3.80%). Pages 7-19 removed, registration data. MRID 44877106.
Document (PDF) (335 KB PDF).
December 01, 1999. Memorandum. 21 Page(s).
Chris Jiang. Risk Assessment & Science Support Branch.
Review of the Leach Rate of Zinc Omadine from Ecoloflex Paint.
Reference Code BEA469/G043, in Synthetic Seawater (3.80%).
Pages 7-19 removed, registration data. MRID 44877105.
Document (PDF) (358 KB PDF).
February 09, 2000. Memorandum. 2 Page(s).
Nancy Whyte. Product Science Branch AD.
Product Chemistry Review of: Intersmooth 360 Ecoflex SPC Antifouling
Paint. Reg. No. 2693-RIT.
Document (PDF) (75 KB PDF).
October 13, 2000. Memorandum. 1 Page(s).
A. Najm Shamim. Risk Assessment & Science Support Branch.
Review of Intersmooth 365 Ecoflex Spc Antifouling BEA 363 Paint. [Zinc
omadine leach rates interim report.]. MRID#: 445872-09.
Document (PDF) (51 KB PDF).
August 08, 2008. Memorandum. 23 Pages.
Nathan Mottl. Risk Assessment & Science Support Branch.
Zinc 2-pyridinethiol-1-oxide (Zinc Omadine®): Occupational and
Residential Exposure Risk Assessment for New Uses (Textiles) on EPA
Reg Numbers 1258-840 and 1258841. MRID Nos.: 47311501 and
47311502. DP Barcode: D350287.
Document (PDF) (1167 KB PDF).
May 12, 2009. Memorandum. 53 Pages.
Timothy Dole. Regulatory Management Branch II.
Review of "Assessment of Potential Inhalation and Dermal Exposure to Zinc
Pyrithione During Outdoor Painting of Ship Hulls with Commercial Antifoulant Paint
Containing Zinc Omadine". DP Barcode: D311326. MRID No. 467070-01.
Document (PDF) (1951 KB PDF).
Attachment(s) Following:
June 28, 2006. Review.
Traci Brody/Ron Lee. OPP.
Antifoulant Application Worker Exposure Monitoring Study.
December 05, 2008. Memorandum.
Kelly Sherman. Office of Pesticide Programs.
Ethics Review of Zinc Pyrithione Worker Exposure Study.
*End of Attachments*