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Index of Cleared Science Reviews for Trichlorfon (Pc Code 057901)
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Undated. Data Eval. Rec. 10 Page(s).
Susan Brett. Clement Associates.
Metabolism of 0,0-dimethyl-2,2,2-trichloro-1-hydroxyethyl phosphonate
(Dipterex) in Mammalian Nervous Tissue and Kinetics Involved in its
Reaction with Acetylcholine esterase.
Document (PDF) (405 KB PDF).
Undated. Data Eval. Rec. 12 Page(s).
Donald Hill. Southern Research Institute.
Mechanism of Inhibition In Vitro of Mammalian Acetylcholinesterase and
Cholinesterase in Solutions of.. . Trichlorfon.
Document (PDF) (461 KB PDF).
Undated. Data Eval. Rec. 13 Page(s).
Donald Hill. Southern Research Institute.
Effect of Metrifonate on Blood Cholinesterases in Children During
Treatment of Schistosomiasis.
Document (PDF) (443 KB PDF).
Undated. Data Eval. Rec. 3 Page(s).
Donald Hill. Southern Research Institute.
The Persistance in the Blood of Hens of Organophosphoric Compounds,
Applied by Different Ways.
Document (PDF) (123 KB PDF).
Undated. Data Eval. Rec. 3 Page(s).
Jack Radomski. Clement Associates.
The Possibility of Injury by Trichlorfon in the Young of Lactating Rats.
Document (PDF) (114 KB PDF).
Undated. Data Eval. Rec. 3 Page(s).
John Peckham. Southern Research Institute.
Motor Nerve Conduction Velocity and Electromyogram in Triorthocresyl-
Phosphate Poisoning.
Document (PDF) (145 KB PDF).
Undated. Data Eval. Rec. 3 Page(s).
Susan Brett. Clement Associates.
A Case of Hypocholinesterasemia Induced by Trichlorfon.
Document (PDF) (108 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
Donald Hill. Southern Research Institute.
Studies on the Percutaneous Absorption of 32p-Labeled Systemic,
Minimally Toxic Organophosphorus Compounds (OPC) in Cattle.
Document (PDF) (142 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
Duncan Turnbull. Clement Associates.
Interaction of Dichlorvos and Anticholinesterases on the In Vivo Inhibition
of Human Blood Cholinesterases.
Document (PDF) (160 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
Gregory Helms. Clement Associates.
Histophysiological Studies of Rat Organs after Exposure to Foschlor.
Document (PDF) (161 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
John Peckham. Southern Research Institute.
Acute Trichlorfon Poisoning Complicated by Polyneuritis.
Document (PDF) (170 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
William Waud. Southern Research Institute.
Studies on Organophosphorus Preparations in Cattle, Pigs, and Sheep
with Special Reference to Cholinesterase Activity.
Document (PDF) (162 KB PDF).
Undated. Data Eval. Rec. 4 Page(s).
Yvonne Presley. Clement Associates.
Dipterex: Inhalation Toxicity Data.
Document (PDF) (149 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Glynn Wheeler. Southern Research Institute.
Alkylation of Guanine in Mice In Vivo by Organophosphorus Insecticides.
Document (PDF) (184 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Gregory Helms. Clement Associates.
Experiments on the Effects of Foschlor in Drinking Water on Some of the
Histochemical Reactions of the Liver of White Rats Under Long-Term
Experimental Conditions.
Document (PDF) (214 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Jack Kalin. Southern Research Institute.
Studies on the Effect of the Phosphororganic Preparation on the Organism
of Pregnant Rats, Fetuses, and the Cells in Tissue Culture.
Document (PDF) (215 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
John Peckham. Southern Research Institute.
Household Poisoning by Trichlorfon, Complicated by Polyneuritis.
Document (PDF) (242 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Patricia Noker. Southern Research Institute.
In Vitro and In Vivo Studies on the Percutaneous Absorption of
Systemically Phosphorus-32-Labeled Insecticidal Organophosphorus
Compounds in Cattle.
Document (PDF) (172 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Susan Brett. Clement Associates.
Morphological Composition of the Blood in Persons Working with a
Complex of Organochlorine and Organophosphorus Pesticides.
Document (PDF) (194 KB PDF).
Undated. Data Eval. Rec. 5 Page(s).
Susan Brett. Clement Associates.
Neuropsychic Changes in Persons Suffering from Acute Poisoning with
Organophosphorus Insecticides.
Document (PDF) (172 KB PDF).
Undated. Data Eval. Rec. 6 Page(s).
Cecil Felkner. Dynamac Corporation.
Hematotoxic and Hepatotoxic Action of Pesticidal Organic Phosphorus
Compounds.
Document (PDF) (288 KB PDF).
Undated. Data Eval. Rec. 6 Page(s).
Jack Kalin. Southern Research Institute.
The Effect of Acute Intoxication by Dichlorvos and Trichlorfon on the
Activities of Some Rat Brain Esterases.
Document (PDF) (218 KB PDF).
Undated. Data Eval. Rec. 6 Page(s).
John Peckham. Southern Research Institute.
Neurological Disorders in Acute Chlorophos Poisoning.
Document (PDF) (247 KB PDF).
Undated. Data Eval. Rec. 6 Page(s).
Yvonne Presley. Clement Associates.
The Acute Toxicity of Pesticides to Rats.
Document (PDF) (249 KB PDF).
Undated. Data Eval. Rec. 7 Page(s).
Susan Rieth. Clement Associates.
Fate of the Methyl Groups of Dipterex in Vivo.
Document (PDF) (319 KB PDF).
Undated. Data Eval. Rec. 8 Page(s).
David Bradley. Clement Associates.
Studies on the Toxicity and Effect of Dipterex in Rabbits.
Document (PDF) (328 KB PDF).
Undated. Data Eval. Rec. 8 Page(s).
James Plautz. Clement Associates.
The Effect of Foschlor Administered in Water on the Ontogenetic
Development of White Rats and Their Progency.
Document (PDF) (334 KB PDF).
Undated. Data Eval. Rec. 8 Page(s).
James Plautz. Clement Associates.
The Effect of Foschlor in Drinking Water on the Internal Organs of Three
Successive Generations of Rats.
Document (PDF) (344 KB PDF).
Undated. Data Eval. Rec. 9 Page(s).
Donald Hill. Southern Research Institute.
Regeneration of Cholinesterase Activities in Humans and Rats after
Inhibition by 0,0-dimethyl-2,2-dichlorovinyl phosphate.
Document (PDF) (330 KB PDF).
Undated. Data Eval. Rec. 9 Page(s).
John Peckham. Southern Research Institute.
Acute Chlorofos Poisoning.
Document (PDF) (383 KB PDF).
Undated. Data Eval. Rec. 9 Page(s).
John Peckham. Southern Research Institute.
Neurological Disorders in Chlorophos Poisoning.
Document (PDF) (375 KB PDF).
Undated. Review. 7 Page(s).
Toxicology Branch.
Teratology in Rats.
Document (PDF) (458 KB PDF).
July 01, 1969. Report. 3 Page(s).
Calvin Menzie. U.S. Department of the Interior.
Metabolism of Pesticides (report excerpt pages 322-323).
Document (PDF) (299 KB PDF).
January 01, 1974. Report. 3 Page(s).
Calvin Menzie. U.S. Department of the Interior.
Metabolism of Pesticides - An Update (report excerpt pages 370-371).
Document (PDF) (267 KB PDF).
October 26, 1977. Review. 7 Page(s).
Diane Courtney. Toxicology Branch.
Validation Report. The Effect of Chlorophos on the Energy Metabolism in
the Placenta and Organs of the Intrauterine Fetus.
Document (PDF) (364 KB PDF).
January 01, 1980. Report. 2 Page(s).
Calvin Menzie. U.S. Department of the Interior.
Metabolism of Pesticides - Update III (report excerpt page 389).
Document (PDF) (178 KB PDF).
April 15, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Test on Bacterial Systems. Acc No. 249535..
Document (PDF) (130 KB PDF).
April 15, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
(Oral) Rabbit Teratology. Accession No. 244915.
Document (PDF) (261 KB PDF).
April 15, 1983. Data Eval. Rec. 7 Page(s).
Irving Mauer. Toxicology Branch.
Three-Generation Reproduction Assay - Rats (Feed). Accession No.
244915.
Document (PDF) (327 KB PDF).
June 03, 1983. Memorandum. 20 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon (EPA Reg. No. 3125-9) Studies Submitted for Registration
Standard Development. [3(c)(2)(B) Data Call-In]. Accession Nos.
244915/249535.
Document (PDF) (866 KB PDF).
July 25, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Review.
MRID No. 05015000.
Document (PDF) (36 KB PDF).
July 25, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Potentiative and Synergistic Effects.
Document (PDF) (47 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral Toxicity in Sheep and Cattle.
Document (PDF) (130 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity.
Document (PDF) (87 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism, in vitro.
Document (PDF) (140 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism. Pesticidal Chemicals Affecting Some Energy-Linked
Functions of Rat Liver Mitochondria in vitro.
Document (PDF) (100 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity.
Document (PDF) (110 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity in Drosophila melanogaster Strains D-32 and Muller-5.
Document (PDF) (113 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity: 1. Gene Mutation in Aspergillus nidulans Strain 35. 2.
Genetic Damage (Somatic Crossing-Over and Non-Disjunction) in A.
nidulans Strain P.
Document (PDF) (87 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity: 1. Gene Mutation in Drosophila melanogaster. 2.
Chromosome Aberrations in D. melanogaster.
Document (PDF) (111 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Reproduction/Teratology.
Document (PDF) (129 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subacute Oral Toxicity in Rat. Morphologic and Histochemical Changes
in the Gastric Mucosa of Rats During Subacute Poisoning with Chlorofos.
Document (PDF) (132 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Oral Toxicity in Rats. Ultrastructural Changes in the Levels
of Rats after Chronic Exposure to Dipterex.
Document (PDF) (99 KB PDF).
July 25, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Toxicity.
Document (PDF) (119 KB PDF).
July 25, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism. The Alkylating Effect of Trichlorfon in Warm-Blooded Animals.
Document (PDF) (141 KB PDF).
July 26, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Review. Mutagenic Activity of Pesticides.
MRID No. 05015000.
Document (PDF) (31 KB PDF).
July 26, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Review. Mutagenic, Teratogenic, and Carcinogenic
Properties of Pesticides.
Document (PDF) (29 KB PDF).
July 26, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Review. The Experimental Testing of Chemical Substances
for Embryotoxicity, Teratogenicity and Mutagenicity-Oncogenic
Reactions of the Laboratory Mouse to these Substances and Assignment
of these Reactions. A Critical Analysis of the Methods.
Document (PDF) (34 KB PDF).
July 26, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Studies on Organophosphorus Insecticides.
Document (PDF) (30 KB PDF).
July 26, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity: Worker Exposure.
MRID No. 05007897.
Document (PDF) (35 KB PDF).
July 27, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations in Mice (Dominant Lethal Test). Detection of
Chemical Mutagens by the Dominant Lethal Assay in the Mouse.
Document (PDF) (99 KB PDF).
July 27, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations in Mice (Dominant Lethal Test). The
Mutagenicity of Desmethyl Trichlorfon in Dominant Lethal Test on Mice.
Document (PDF) (135 KB PDF).
July 27, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Reproduction and Fetal Metabolism Evaluation of Orally Administered
Trichlorfon in the Rabbit.
Document (PDF) (165 KB PDF).
July 27, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Carcinogenicity: Oral Feeding in Rats.
Document (PDF) (165 KB PDF).
July 27, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Reproductive and Teratogenic Evaluation in the Mouse of Trichlorfon
Administered by Intraperitoneal Injection.
Document (PDF) (200 KB PDF).
July 29, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity.
Document (PDF) (64 KB PDF).
July 30, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Responses of Cell Cultures to Insecticides.
Document (PDF) (43 KB PDF).
July 30, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral Toxicity in Rats.
MRID 00005494.
Document (PDF) (63 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
90-Day Feeding Study in Rabbits.
Document (PDF) (100 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Inhalation Toxicity.
MRID 00081189.
Document (PDF) (77 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral Toxicity in Rats.
Document (PDF) (108 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral Toxicity Potentiation Study in Rats.
MRID 00062031.
Document (PDF) (102 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity in Rats by the Intraperitoneal Route.
MRID 00091100.
Document (PDF) (92 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations in Mice (Micronucleus Test)
MRID 00072192.
Document (PDF) (122 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Chronic Toxicity.
Document (PDF) (108 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Dermal Toxicity in Dogs.
MRID 00081203.
Document (PDF) (110 KB PDF).
July 30, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Toxicity (Subacute) in Rats by the Intraperitoneal Route.
MRID 00091815.
Document (PDF) (95 KB PDF).
July 30, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Acute Delayed Neurotoxicity Study in Chickens - Subcutaneous and
Oral Routes.
Document (PDF) (181 KB PDF).
July 30, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Carcinogenicity.
Document (PDF) (158 KB PDF).
July 30, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism and Toxicity in Rats.
MRID 00005296.
Document (PDF) (164 KB PDF).
July 30, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism in Rats, Certain Insect Species, and Cotton Plants.
Document (PDF) (190 KB PDF).
July 30, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations in Mice (Dominant Lethal Test).
Document (PDF) (233 KB PDF).
July 30, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Chronic Oral (Intragastric) Toxicity in Rats.
Document (PDF) (159 KB PDF).
July 30, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Reproductive Evaluation of Trichlorfon Administered to the Diet of Hens.
MRID 0062005.
Document (PDF) (195 KB PDF).
July 30, 1983. Data Eval. Rec. 6 Page(s).
Irving Mauer. Toxicology Branch.
Carcinogenicity: Feeding in Rats.
Document (PDF) (191 KB PDF).
July 30, 1983. Data Eval. Rec. 8 Page(s).
Irving Mauer. Toxicology Branch.
Carcinogenicity - Oral.. . in Mice.
MRID 0069026.
Document (PDF) (228 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Dermal Toxicity in Bulls.
Document (PDF) (39 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity Human Studies. Analysis of the Causes of Death in Acute
Poisoning in Children.
Document (PDF) (38 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity Human Studies. Hygienic Working Conditions During the
Successive Application of Kotoran and Anthio and their Effect on Workers.
MRID No. 05021423.
Document (PDF) (41 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity Human Studies. Pathogenesis of Cardiac Rhythm and
Conductivity Disorders in Cases of Acute Poisoning with the
Organophosphorus Insecticides.
Document (PDF) (41 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity Human Studies. The Effect of Organophosphorus
Compounds in Low Concentrations on the Body.
Document (PDF) (39 KB PDF).
August 05, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity Review.
Document (PDF) (40 KB PDF).
August 05, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Acute Dermal Toxicity in Cattle.
Document (PDF) (78 KB PDF).
August 05, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Teratogenic and Biochemical Evaluation of Trichlorfon in Chick Embryos
MRID 05000968.
Document (PDF) (65 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral and Dermal Toxicity in Rats.
MRID 00055139.
Document (PDF) (98 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Antidotal Study in Rats.
MRID 00081337.
Document (PDF) (102 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Embryotoxic Evaluation of Trichlorfon in Chicken Embryos.
Document (PDF) (109 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Embryotoxic Evaluation of Trichlorfon Introduced into the Chicken Egg.
Document (PDF) (130 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Gene Mutations: 1. Salmonella typhimurium LT-2 Strains. 2. Escherichia
coli WP2 Strains.
MRID 05014760.
Document (PDF) (111 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Human Effects from Oral Intake.
Document (PDF) (154 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Human Observations.
Document (PDF) (103 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
In Vitro Biochemical Toxicity.
Document (PDF) (99 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Metabolism in Cow.
MRID 00005297.
Document (PDF) (138 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity: 1. Gene Mutations in Durum Wheat. 2. Chromosomal
Aberrations in Durum Wheat.
Document (PDF) (117 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Inhalation Toxicity in Rats.
Document (PDF) (103 KB PDF).
August 05, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Teratogenic Evaluation of Trichlorfon Administered in the Feed to the Rat.
Document (PDF) (152 KB PDF).
August 05, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Acute Toxicity in Rabbits (Oral Gavage).
Document (PDF) (162 KB PDF).
August 05, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations in Humans.
Document (PDF) (152 KB PDF).
August 05, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
1. Acute Toxicity in Rats, Mice, and Guinea Pigs. 2. Subchronic Toxicity in
Rats. 3. In Vitro and In Vivo Cholinesterase Determinations in Rats. 4.
Metabolism in Rats.
MRID 00081186.
Document (PDF) (263 KB PDF).
August 05, 1983. Data Eval. Rec. 6 Page(s).
Irving Mauer. Toxicology Branch.
Acute and Subchronic Toxicity (and Antidotal Effects) in Calves.
Document (PDF) (237 KB PDF).
August 05, 1983. Data Eval. Rec. 7 Page(s).
Irving Mauer. Toxicology Branch.
Prenatal/Postnatal (Reproduction) Toxicity Evaluation in the Pig of
Trichlorfon Administered in the Feed.
Document (PDF) (325 KB PDF).
August 09, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral Toxicity of VMI Trichlorfon Pour-on Cattle Insecticide.
Document (PDF) (41 KB PDF).
August 09, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Dermal Irritation in Rabbits.
Document (PDF) (45 KB PDF).
August 09, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Effects on Lysozymal Activity.
Document (PDF) (38 KB PDF).
August 09, 1983. Data Eval. Rec. 1 Page(s).
Irving Mauer. Toxicology Branch.
Gene Mutations in Escherichia coli WP2.
MRID No. 05022240.
Document (PDF) (37 KB PDF).
August 09, 1983. Data Eval. Rec. 2 Page(s).
Irving Mauer. Toxicology Branch.
Ocular Irritation in Rabbits.
Document (PDF) (108 KB PDF).
August 09, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Effects on Enzyme Activities Following Acute and Subchronic
Administration to Rats.
Document (PDF) (115 KB PDF).
August 09, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Gene Mutations: 1. Salmonella typhimurium LT-2 Strains. 2.
Streptomyces coelicolor A3 MRID 05011869, 05020822.
Document (PDF) (162 KB PDF).
August 09, 1983. Data Eval. Rec. 3 Page(s).
Irving Mauer. Toxicology Branch.
Neurotoxicity in Chickens.
MRID 00013561.
Document (PDF) (107 KB PDF).
August 09, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Chromosomal Aberrations: 1. Mouse Bone Marrow Cells. 2. Human
Lymphocyte Cultures.
MRID 05000617, 05002806.
Document (PDF) (179 KB PDF).
August 09, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Evaluation of Trichlorfon Effects on Bitches and Nursing Pups.
MRID 00091879.
Document (PDF) (170 KB PDF).
August 09, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Gene Mutations in Salmonella typhimurium TA98 and TA100.
Document (PDF) (225 KB PDF).
August 09, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Mutagenicity: 1. Gene Mutations in Salmonella typhimurium and
Escherichia coli. 2. Chromosome Aberrations (Mitotic Recombination) in
Saccharomyces cerevisiae. 3. DNA Repair Damage in E. coli and
Bacillus subtilis. 4. Unscheduled DNA Synthesis in H.
Document (PDF) (293 KB PDF).
August 09, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Postnatal Evaluation of Orally Administered Trichlorfon in Rats Exposed In
Utero.
Document (PDF) (252 KB PDF).
August 15, 1983. Data Eval. Rec. 12 Page(s).
Irving Mauer. Toxicology Branch.
Teratogenic Evaluation of Orally Administered Trichlorfon in the Rat,
Hamster, and Mouse.
Document (PDF) (660 KB PDF).
August 15, 1983. Data Eval. Rec. 9 Page(s).
Irving Mauer. Toxicology Branch.
Reproduction and Teratogenic Evaluation in the Mouse of Two
Trichlorfon Analogs Administered by Intraperitoneal Injection.
Document (PDF) (464 KB PDF).
October 21, 1983. Data Eval. Rec. 6 Page(s).
Irving Mauer. Toxicology Branch.
Chronic Oral Toxicity - Dogs. Acc. 090786.
Document (PDF) (297 KB PDF).
October 24, 1983. Data Eval. Rec. 7 Page(s).
Irving Mauer. Toxicology Branch.
Chronic Oral Toxicity. Acc. 090786.
Document (PDF) (345 KB PDF).
November 10, 1983. Review. 2 Page(s).
Irving Mauer. Toxicology Branch.
Reproduction Study in Rats.
Document (PDF) (119 KB PDF).
November 10, 1983. Review. 2 Page(s).
Irving Mauer. Toxicology Branch.
Teratogenicity in Rats.
Document (PDF) (106 KB PDF).
November 15, 1983. Review. 2 Page(s).
Irving Mauer. Toxicology Branch.
Inhalation Teratogenicity in Rats.
Document (PDF) (128 KB PDF).
November 16, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Toxicity in Dogs. Acc. 090786.
Document (PDF) (163 KB PDF).
November 16, 1983. Data Eval. Rec. 4 Page(s).
Irving Mauer. Toxicology Branch.
Three-Month Subchronic Administration of Trichlorfon to the Dog in the
Diet. Acc. 090786.
Document (PDF) (185 KB PDF).
November 16, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Acute Oral, Acute Dermal, and Subchronic Oral Toxicity in Rats. Acc.
090786.
Document (PDF) (275 KB PDF).
November 16, 1983. Data Eval. Rec. 5 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic Feeding Study in Rats. Acc. 090786.
Document (PDF) (230 KB PDF).
November 18, 1983. Review. 2 Page(s).
Irving Mauer. Registration Action Branch 3.
Teratogenicity (Oral) in Pigs.
Document (PDF) (93 KB PDF).
November 30, 1983. Review. 2 Page(s).
Irving Mauer. Toxicology Branch.
Potentiation (rbc-AChe Activity).
Document (PDF) (88 KB PDF).
December 12, 1983. Review. 1 Page(s).
Irving Mauer. Toxicology Branch.
Reproduction/Teratology in Chickens, Rats and Rabbits.
Document (PDF) (74 KB PDF).
January 03, 1984. Review. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute (Delayed) Neurotoxicity in Hens.
Document (PDF) (56 KB PDF).
January 19, 1984. Review. 4 Page(s).
Irving Mauer. Toxicology Branch.
Oncogenicity in Rats.
Document (PDF) (332 KB PDF).
February 06, 1984. Review. 2 Page(s).
Irving Mauer. Toxicology Branch.
Acute (Delayed) Neurotoxicity in Hens.
Document (PDF) (131 KB PDF).
February 08, 1984. Memorandum. 3 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - RS. Oncogenicity study, rats..
Document (PDF) (145 KB PDF).
February 17, 1984. Review. 1 Page(s).
Irving Mauer. Toxicology Branch.
Acute (Delayed) Neurotoxicity in Hens.
Document (PDF) (81 KB PDF).
February 17, 1984. Review. 1 Page(s).
Irving Mauer. Toxicology Branch.
Neurotoxicity in Hens.
Document (PDF) (84 KB PDF).
February 17, 1984. Review. 1 Page(s).
Irving Mauer. Toxicology Branch.
Subchronic (21-Day) Neurotoxicity in Rats.
Document (PDF) (76 KB PDF).
June 27, 1985. Memorandum. 26 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon RS - Evaluation of Data Submitted under Accession Nos.
256446, 256447, and 257599. Registration No. 3125-9.
Document (PDF) (1213 KB PDF).
July 16, 1985. Memorandum. 10 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon RS - Studies Submitted to Satisfy Data Requirements.
Accession No. 257819. ID No. 3125-9.
Tox review 004561.
Document (PDF) (424 KB PDF).
September 19, 1985. Memorandum. 2 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Dylox 80% SPA, EPA Registration No. 3125-66. Acute Studies
Waiver. Inert ingredient information on page 2 is not included.
Document (PDF) (98 KB PDF).
November 26, 1985. Memorandum. 4 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Data Requirements Noted in Registration Standard.
Document (PDF) (191 KB PDF).
February 03, 1986. Memorandum. 3 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Company Response Dated October 7, 1985 to Previous
Toxicology Branch (TB) Reviews of Submitted Studies, and Additional
Data, Accession No. 259968.
Tox review 004915.
Document (PDF) (141 KB PDF).
February 06, 1986. Memorandum. 4 Page(s).
Herbert Harrison. Insecticide-Rodenticide Branch.
Mobay Requests for Data Substitutions and Time Extensions of Data
Requirements for Trichlorfon.
Document (PDF) (193 KB PDF).
March 31, 1986. Memorandum. 5 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Company Response Dated November 22, 1985 to Previous
Toxicology Branch Reviews of Submitted Studies - Dylox 80% SPA, EPA
Registration No. 3125-66, Reregistration Standard.
Document (PDF) (189 KB PDF).
July 08, 1986. Memorandum. 5 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Company Response to Mutagenicity Review. Submitted
under Accession No. 262090.
Document (PDF) (203 KB PDF).
October 27, 1986. Memorandum. 2 Page(s).
Irving Mauer. Toxicology Branch.
Trichlorfon - Request for Waiver of Acute Toxicity Data - Dylox 80
Concentrate. EPA Accession No. 262471. ID No. 3125-GTR. Inert
ingredient information on page 2 is not included.
Document (PDF) (180 KB PDF).
February 16, 1988. Memorandum. 1 Page(s).
Francis Suhre. Residue Chemistry Branch.
DDVP/Naled/Trichlorfon; Request for Updated Market Share Data; No
MRID No. ; No RCB No.
Document (PDF) (47 KB PDF).
September 22, 1988. Memorandum. 30 Page(s).
Francis Suhre. Dietary Exposure Branch.
Dietary Exposure Assessment for 2,2 dichlorovinyl dimethylphosphate
(DDVP) from Registered Uses of Naled and Trichlorfon (PHIs < 7 Days);
No MRID No. ; DEB Nos. 3727 and 4056.
Document (PDF) (1305 KB PDF).
September 06, 1989. Analysis. 7 Page(s).
Health Effects Division. Health Effects Division.
Anticipated Residue Information for Caswell Number 385, Trichlorofon.
Document (PDF) (499 KB PDF).
April 10, 1990. Memorandum. 4 Page(s).
Leung Cheng. Dietary Exposure Branch.
EPA # 239-1633. Naled & Trichlorfon. Special Review Data Call-In
Requirements. No MRID #. DEB #6254.
Document (PDF) (220 KB PDF).
May 15, 1990. Memorandum. 76 Page(s).
Richard Schmitt. Dietary Exposure Branch.
Trichlorfon Product Chemistry and Residue Chemistry Registration
Standard Update. Pages 25-32 are not included - confidential statement of
formula, quality control and manufacturing process information.
Document (PDF) (4242 KB PDF).
July 23, 1990. Memorandum. 22 Page(s).
Richard Schmitt. Dietary Exposure Branch.
Addendum to Trichlorfon Product Chemistry Registration Standard
Update. Pages 18-22 are not included - confidential statement of formula,
quality control and manufacturing process information.
Document (PDF) (891 KB PDF).
February 24, 1994. Memorandum. 10 Page(s).
George Ghali. Health Effects Division.
RfD/Peer Review Report of Trichlorfon.
Document (PDF) (945 KB PDF).
February 28, 1995. Memorandum. 26 Page(s).
Melba Morrow. Toxicology Branch.
Carcinogenicity Peer Review of Trichlorfon.
Tox review 011437.
Document (PDF) (1822 KB PDF).
January 28, 1999. Memorandum. 4 Page(s).
Lori Brunsman. Science Analysis Branch, HED.
ADDENDUM to Trichlorfon Qualitative Risk Assessment on Charles
River CD-1 Mouse Dietary Study.
MRID 407824-01, 408443-01.
Document (PDF) (185 KB PDF).
February 02, 1999. Memorandum. 4 Page(s).
Linda Taylor. Reregistration Branch, HED.
TRICHLORFON: Revised Tumor Analysis of Mouse Carcinogenicity
Study for Consideration by the HED Cancer Assessment Review
Committee.
MRID 44627701.
Document (PDF) (253 KB PDF).
July 15, 1999. Memorandum. 16 Page(s).
Sanjivani Diwan. HED.
Trichlorfon-Report of the Cancer Assessment Review Committee Tox
review 013567.
Document (PDF) (765 KB PDF).
July 26, 2005. Memorandum. 39 Page(s).
Abdallah Khasawinah. Reregistration Branch HED.
Trichlorfon-Toxicology Study Reports [developmental neurotoxicity in the
rat] DP Code: D272254 MRID 46205301.
Tox review 0052426.
Document (PDF) (1995 KB PDF).
August 22, 2006. Memorandum. 38 Page(s).
Abdallah Khasawinah. Reregistration Branch 4 HED.
Trichlorfon-Toxicology Study Reports. PC Code: 057901
Reregistration Case #: 0104. TXR: 0054212. DP Barcode: D322591 and D321550.
MRIDs: 46647401, 46647402, 46635401, 46647404, 46647403, 46635601, and 46635501.
(MRID No. 46205301).
Document (PDF) (2079 KB PDF).
December 01, 2007. DER. 13 Page(s).
Louis Scarano. Toxicology Branch.
DATA EVALUATION RECORD TRICLORFON (DYLOX TECHNICAL)
Study Type: SPECIAL STUDIES, CHOLINESTERASE INHIBITION [NON-GUIDELINE]
MRID 46647404 (peak effect - preweaning); 46647403 (acute - preweaning);
46635601 (repeated - preweaning). DP BARCODE: DP322591.
Document (PDF) (493 KB PDF).