December 11 - 12, 2003 SAP meeting Agenda
FIFRA SCIENTIFIC ADVISORY PANEL (SAP)FIFRA
SCIENTIFIC ADVISORY PANEL (SAP)
OPEN MEETING
December 11 and 12, 2003
FIFRA SAP WEB SITE https://www.epa.gov/scipoly/sap/
OPP Docket Telephone: (703)305-5805
PHYSIOLOGICALLY-BASED PHARMACOKINETIC/PHARMACODYNAMIC
MODELING: PRELIMINARY EVALUATION AND CASE STUDY FOR THE
N-METHYL CARBAMATE PESTICIDES: A CONSULTATION
Thursday, December 11, 2003
Sheraton Crystal City Hotel
1800 Jefferson Davis Highway
Arlington, Virginia 22202
703-486-1111
Please note that all times are approximate.
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8:30 AM Meeting Opening - Stephen M. Roberts, Ph.D.
(Chair of the FIFRA SAP)
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8:35 AM Introduction of Panel Members - Christopher Portier, Ph.D. (FIFRA SAP Session Chair)
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8:40 AM Administrative Procedures by Designated
Federal Official - Mrs. Myrta R. Christian
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8:45 AM Opening Remarks - Mr. Jim Jones (Director,
Office of Pesticide Programs, Office of Prevention, Pesticides,
and Toxic Substances, EPA)
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8:55 AM Introduction and Background - Randolph Perfetti,
Ph.D. (Office of Pesticide Programs, EPA)
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9:00 AM Scope and purpose: Anna Lowit, Ph.D. (Office
of Pesticide Programs, EPA)
PBPK/PD models and cumulative risk assessment: Rory Connolly, Sc.D. (CIIT Centers for Health Research)
Pharmacodynamic modeling of the N-methyl carbamate pesticides: Jerry Blancato, Ph.D, Curtis Dary, Ph.D. (Office of Research and Development, National Exposure Research Lab, EPA)
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10:00 AM Break
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10:15 AM Computer implementations and simulation
examples: Jerry Blancato, Ph.D, Fred Power, M.S. (Office of Research
and Development, National Exposure Research Lab, EPA)
Model evaluation: R. Woodrow Setzer, Ph.D. (Office of Research and Development, National Health and Environmental Effects Laboratory, EPA).
Extrapolation of PBPK/PD models from laboratory animals to humans and data needs for the PBPK/PD model(s) for the N-methyl carbamate pesticides: Rory Connolly, Sc.D. (CIIT Centers for Health Research)
Conclusions and summary: Anna Lowit, Ph.D. (Office of Pesticide Programs, EPA)
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12:00 PM Lunch
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1:00 PM Public Comments
- 2:00 PM Questions to the Panel