Note: This information is provided for reference purposes only. Although the information provided here was accurate and current when first created, it is now outdated.

UPDATE BRIEFING PAPER #2

SCIENCE POLICY GUIDANCE DOCUMENTS

The following list includes the science policy documents that EPA is releasing for public comment. It lists the publication date for those that have already been published in draft and the month EPA expects to publish the others. It also includes several related documents that will be released for public comment but that are not part of the nine science policies. See UPDATE BRIEFING PAPER #1 for a copy of the October 29 Federal Register notice.

Applying the FQPA 10-Fold Safety Factor

• Standard Operating Procedure for the Use of the FQPA Factor (Publication planned for April 1999)
• 10X Task Force and OPP Guidance Documents (Publication planned for April 1999)

Dietary Exposure Assessment - Whether and How to Use Monte Carlo Analyses and the 99.9 Percentile Issue

• Guidance for Submission of Probabilistic Human Health Exposure Assessments to the Office of Pesticide Programs (Notice of Availability published in the Federal Register November 5, 1998)
• Choosing a Percentile of Acute Dietary Exposure as a Threshold of Regulatory Concern (Publication planned for March 1999)
• Use of the Pesticide Data Program in Acute Dietary Exposure Assessment (Publication planned for May 1999)

Exposure Assessment - Interpreting "No Residues Detected"

• A Statistical Method for Incorporating Nondetected Pesticide Residues into Human Health Dietary Exposure Assessments (Notice of Availability published in the Federal Register December 4, 1998)
• Assigning Values to Nondetected/Nonquantified Pesticide Residues in Human Health Dietary Exposure Assessments (Notice of Availability published in the Federal Register December 4, 1998)
• Proposed Threshold of Regulation Policy When a Food Use Does Not Require a Tolerance (Notice of Availability published in the Federal Register December 4, 1998)

Dietary Exposure Estimates

• User's Guide to Available EPA Information on Assessing Dietary (Food) Exposure to Pesticides (Notice of Availability published in the Federal Register January 4, 1999)

Drinking Water Exposures

• Dietary (Drinking Water) Exposure Assessments (Notice of Availability published in the Federal Register January 4, 1999)
• Drinking Water Screening-Level Assessments (includes "cropped areas") (Publication planned for August 1999)
• Revised SOP for Drinking Water Assessments (includes reservoir model) (Publication planned for August 1999)

Assessing Residential Exposure

• Standard Operating Procedures (SOPs) for Residential Exposure Assessment (Notice of Availability published in the Federal Register January 4, 1999)
• Framework for Assessing Non-occupational, Non-dietary (Residential) Exposure (Notice of Availability published in the Federal Register January 4, 1999)
• Working Draft-Appendix A-Summary of Assumptions for the Residential SOPs (Notice of Availability published in the Federal Register January 4, 1999)
• Working Draft-Appendix B-Surrogate Phed VI.I Unit Exposure Values (Notice of Availability published in the Federal Register January 4, 1999)

Aggregating Exposures from all Non-Occupational Sources

• Guidance for Performing Aggregate Exposure and Risk Assessment (Publication planned for May 1999)

• SOP for Performing Aggregate Exposure and Risk Assessment (Publication planned for May 1999)

How to Conduct a Cumulative Risk Assessment for Organophosphate or Other Pesticides with a Common Mechanism of Toxicity

• Guidance for Identifying Pesticide Chemicals and Other Substances That Have a Common Mechanism of Toxicity (Notice of Availability published in the Federal Register August 6, 1998)

• Cumulative Risk Assessment Guidance (Publication planned for July 1999)

Selection of Appropriate Toxicity Endpoints (or Critical Effects) for Risk Assessments of Organophosphates

• OPP's Science Policy on the Use of Cholinesterase Inhibition for Risk Assessments of Organophosphate and Carbamate Pesticides (Notice of Availability published in the Federal Register November 5, 1998)

Other Policies

• Interim Early Assessment Policy for Organophosphate Pesticides (Publication planned for March 1999)

• The Role of Use-Related Information in Pesticide Risk Assessment and Risk Management (Publication planned for March 1999)
• Data for Refining Anticipated Residue Estimates Used in Dietary Risk Assessments for Organophosphate Pesticides (Publication planned for March 1999)

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updated February 25, 1999