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Pirimiphos-Methyl IRED Facts

EPA has assessed the risks of pirimiphos-methyl and reached an Interim Reregistration Eligibility Decision (IRED) for this organophosphate (OP) pesticide. Provided that risk mitigation measures are adopted, pirimiphos-methyl fits into its own "risk cup"-- its individual, aggregate risks are within acceptable levels. Pirimiphos-methyl also is eligible for reregistration, pending a full reassessment of the cumulative risk from all OPs.

Used primarily on stored corn and sorghum grain and seed, in cattle ear tags and for the fogging treatment of iris bulbs, pirimiphos-methyl residues in food alone do not pose risk concerns. With mitigation reducinposure to pirimiphos-methyl by requiring closed system mixing and loading systems for admixg worker exture grain and seed treatment, and requiring additional personal protective equipment for workers, risk will not be of concern. Pirimiphos-methyl ecological risks are also below the Agency's level of concern.

EPA's next step under the Food Quality Protection Act (FQPA) is to complete a cumulative risk assessment and risk management decision encompassing all the OP pesticides, which share a common mechanism of toxicity. The interim decision on pirimiphos-methyl cannot be considered final until this cumulative assessment is complete. Further risk mitigation may be warranted at that time.

EPA is reviewing the OP pesticides to determine whether they meet current health and safety standards. Older OPs need decisions about their eligibility for reregistration under FIFRA. OPs with residues in food, drinking water, and other non-occupational exposures also must be reassessed to make sure they meet the new FQPA safety standard.

The pirimiphos-methyl interim decision was made through the OP pilot public participation process, which increases transparency and maximizes stakeholder involvement in EPA's development of risk assessments and risk management decisions. EPA worked extensively with affected parties to reach the decisions presented in this interim decision document, which concludes the OP pilot process for pirimiphos-methyl.


Health Effects


Risk Mitigation

In order to support a reregistration eligibility decision for pirimiphos-methyl, the following risk mitigation measures listed below are necessary:

The OP Pilot Public Participation Process

The organophosphates are a group of related pesticides that affect the functioning of the nervous system. They are among EPA's highest priority for review under the Food Quality Protection Act.

EPA is encouraging the public to participate in the review of the OP pesticides. Through a six-phased pilot public participation process, the Agency is releasing for review and comment its preliminary and revised scientific risk assessments for individual OPs. (Please contact the OP Docket, telephone 703-305-5805, or see EPA's web site, Pesticide Reregistration Status.)

EPA is exchanging information with stakeholders and the public about the OPs, their uses, and risks through Technical Briefings, stakeholder meetings, and other fora. USDA is coordinating input from growers and other OP pesticide users.

Based on current information from interested stakeholders and the public, EPA is making interim risk management decisions for individual OP pesticides, and will make final decisions through a cumulative OP assessment.

Next Steps

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