Highlights of Changes since 1984 Draft 9/15/04 1984 - Part 158 Guidelines Promulgated 1993 - Implementation Paper for the New Paradigm for Ecological Risk Assessment 1995 - Began performing short-term and intermediate term human health risk assessments *Full Implementation of WPS *Agricultural Reentry DCI *Occupational/Residential Turf DCI 1996 - FQPA *Aggregate Risk Assessments *Cumulative Risk Assessments *Sanitizers and food contact disinfectants to EPA *Indirect food additives jointly regulated by EPA & FDA *Safety Factor for sensitivity to infants and children 1996 - Antimicrobial and Biopesticides divisions established 1998 - Began Performing Probabilistic Dietary Risk Assessments. 2004 - Joint Counterpart, Endangered Species Act, Section 7 Consultation, Regulations and Technical Overview Document 2005-2006 - *Endocrine testing program * More Probabilistic Risk Assessments *Update Biochemical and Microbial data requirements *Revise Part 158 Guidelines