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Index of Cleared Science Reviews

Index for Benomyl (Pc Code 099101)

Undated. Review. 143 Pages.
Health Effects Division.
Benomyl Reference Dose for Chronic Oral Exposure (RfD).
DER #1 through DER #17 attached. MRIDs 00088333, 00097284,
00096514, 00151267, 00061618, 00081913, 0097305, 00097318,
00097326, 41887901, 00066773, 00148393, 00115674, 00126522,
43788301, 35352, 66771, 99130, 41607903, 42817003, 43277901.

Undated. Memorandum. 4 Pages.
Melba Morrow. Toxicology Branch I.
ID No. 283750, Metabolite (1-Butyl Isocyanate) from
Aqueous Benlate.

October 23, 1968. Review. 6 Pages.
L.B. Dale. Toxicology Branch.
Methyl-1-(butylcarbamoyl)-2-benzimidazole carbamate.
100-66
Acute, subacute, 90-day feeding, dermal tox, skin irritation
Tox review 004678 excerpt.

March 25, 1970. Memorandum. 13 Pages.
Mary Quaife. Division of Toxicology, FDA.
Benomyl... Requested Tolerances: At 1 ppm on Bananas,
of Which Not More Than 0.2 ppm Shall Be In Pulp After Peel
Is Removed and Discarded (PP No. OFO-906)... Inert info.
on pages 2, 3, 11 and manufacturing process info. on page 2
are not included. Tox review 004678 excerpt.

April 27, 1971. Memorandum. 2 Pages.
George Whitmore. Toxicology Branch.
Memorandum of conference between du Pont and Tox Branch.
Benomyl.
Pesticide Petitions - 906, 1000, 1010, 1045, 1145.
... effect upon the reproduction organs of the test dogs.

May 5, 1971. Memorandum. 12 Pages.
Mary Quaife. Toxicology Branch.
Benomyl... A Fungicide. Requests for Tolerances as Follows:
PP No. 0F0906, 1 ppm on Bananas, of Which No More Than 0.2
ppm Will Be in Pulp; PP No. 0F1000, 15 ppm in or on Plums,
Peaches, Nectarines, Apricots, Cherries, and Prunes...
Inert info on 5, 7 not included. Tox review 004678 excerpt.

June 18, 1971. Letter. 1 Page.
Drew Baker. Petitions Control Branch.
Letter to Mr. Taylor W. Hanavan, E.I. du Pont Company.
petitions... will require a detailed histopathology
examination and report...

July 20, 1971. Memorandum. 2 Pages.
Mary Quaife. Toxicology Branch.
Memorandum of conference between du Pont and Tox Branch.
2-year feeding study on benomyl in dogs.
Benomyl, Pesticide Petitions including No. 0F0906.

October 29, 1971. Memorandum. 4 Pages.
William Boodee. Chemistry Branch.
PP #1F1033. Benomyl on Apples, Pears. Comments on
Amendment of 7/14/71 with Changes in Sections B and F, and
Additional Residue Data.

January 17, 1973. Memorandum. 4 Pages.
Robert Coberly. Toxicology Branch.
Registration No. 352-EXP-73G.
Inert ingredient information on pages 1-3 not included.
Tox review 004678 excerpt.

February 23, 1973. Memorandum. 6 Pages.
Robert Coberly. Toxicology Branch.
Registration No. 352-354. Benlate Benomyl Fungicide.
Acute tox. Inert ingredient information on pages 2-3, and
manufacturing process information on page 2 not included.
Tox review 004678 excerpt.

April 12, 1973. Memorandum. 8 Pages.
Robert Hummel. Chemistry Branch.
PP #2F1218 (FAP #2H5004). Benomyl on Grapes.
Amendment of 1/31/73.

August 14, 1973. Memorandum. 3 Pages.
Robert Hummel. Chemistry Branch.
PP #2F1218 and FAP #2H5004. Benomyl on Grapes.
Amendment of 6/12/73.

November 27, 1973. Memorandum. 5 Pages.
E.M. Bellet. Chemistry Branch.
PP #3F1410 and FAP #3H4033. Benomyl on Citrus.
Evaluation of Analytical Method and Residue Data.

February 1, 1974. Memorandum. 3 Pages.
E.M. Bellet. Chemistry Branch.
PP #3F1410 and FAP #3H4033. Benomyl on Citrus.
Comments on Amendments of 12/7/73.

May 10, 1974. Memorandum. 5 Pages.
Richard Beyak. Chemistry Branch.
PP #4F1452. Benomyl on Tomatoes. Evaluation of the
Analytical Method and Residue Data.
Manufacturing process and inert ingredient information
on page 2 are not included.

November 6, 1974. Memorandum. 2 Pages.
Richard Beyak. Chemistry Branch.
PP #4F1452 and FAP #5H5062. Benomyl on Tomatoes.
Comments on Amendment of 8/16/74.

May 13, 1975. Memorandum. 6 Pages.
Robert Coberly. Toxicology Branch.
Registration No. 538-RGE. Acute toxicology studies.
Inert ingredient information on pages 1 and 2 not included.
Tox review 000719; Tox review 004678 excerpt.

September 9, 1975. Memorandum. 7 Pages.
M.J. Nelson. Chemistry Branch.
PP #5F1612/FAP #5H5084. Benomyl in or on Rice.
Evaluation of Analytical Methods and Residue Data.
Manufacturing process and inert ingredient information
on page 3 are not included.

May 21, 1976. Memorandum. 10 Pages.
Mary Quaife. Toxicology Branch.
Benomyl... tolerances at 0.2 ppm each on wheat, oats,
barley and rye - grain form; at 2.0 ppm each on oats, barley
and rye - straw; and at 15 ppm on wheat straw, requested,
-human safety evaluation.
PP No. 6F1748.

September 7, 1977. Memorandum. 1 Page.
Roland Gessert. Toxicology Branch.
File Symbol 35899-EUP-2. Benomyl 0.3% in 99.7%
Dimethylformamide. Texas A & M University, College Station,
Texas.

January 24, 1978. Memorandum. 7 Pages.
Robert Jaeger. Toxicology Branch.
EPA Reg. No. 192-RET, Benomyl.
Tox review 000722.
Attachment(s) following:

April 23, 1979. Report.
Robert Kavlock. Experimental Biology Division, EPA.
Report on the Status of Teratogenicity Studies with Benomyl.

*End of attachments*

January 30, 1979. Memorandum. 4 Pages.
William Dykstra. Toxicology Branch.
Benlate. Registration #352-354; Caswell #75A (Benomyl)
Acc 236766
Tox review 000723.

October 31, 1979. Memorandum. 3 Pages.
Gary Burin. Toxicology Branch.
PP #9E2259; Request for the Establishment of a Tolerance
for Benomyl at 5 ppm on Turnip Greens.
Caswell #75A; Accession #098945
Tox Review No. 000721.

November 14, 1980. Memorandum. 52 Pages.
Sherell Sterling. Toxicology Branch.
Benlate DF Fungicide.
EPA File Symbol: 352-GOA.
Acute oral, acute dermal, eye and skin irritation.
Acc. No 243043.
Tox review 004678.
Attachment(s) following:

November 14, 1980. Memorandum.
Sherell Sterling. Toxicology Branch.
(continued)
Inert information on pages 6, 7, 13, 14, 19, 20, 28, 35,
37, 43, 44 and 45 is not included. Manufacturing process
information on pages 13 and 19 not included.
Tox review 004678.

*End of attachments*

October 14, 1981. Memorandum. 13 Pages.
Minnie Sochard. Toxicology Branch.
Toxicology Review of Benomyl.
... changes in the teratogenic NOEL and
oncogenic risk from dietary exposure.
Tox review 003728.

November 18, 1981. Review. 6 Pages.
Louis Kasza. Toxicology Branch.
Evaluation of Pathologic Data from Two-Year Feeding Study
in Mice Treated with Benomyl, DuPont Haskell
Laboratory Study.
Tox Review 003726.

December 4, 1981. Memorandum. 7 Pages.
Louis Kasza. Toxicology Branch.
Evaluation of Pathologic Data from
Two-Year Feeding Study in Mice
Treated with INE-965, MBC (Benomyl Metabolite).
Tox review 003727.

May 4, 1982. Memorandum. 8 Pages.
Bertram Litt. Toxicology Branch.
Statistical Evaluation and Oncogenicity Risk
Assessment of Benomyl, Benlate and MBC 2-Year
Feeding Studies in Mice.

January 7, 1983. Memorandum. 8 Pages.
Edwin Budd. Toxicology Branch.
PP 6F1748. Benomyl on Small Grains, Liver and Milk.

March 11, 1983. Memorandum. 2 Pages.
Minnie Sochard. Toxicology Branch.
Benomyl - No. 352-354. Rat Teratology Study.
Accession No. 248563.
Tox Review 002578.

June 27, 1983. Memorandum. 4 Pages.
Roger Gardner. Toxicology Branch.
Benomyl, Additional Teratogenicity Data. Reg. No. 352-354.
Accession Nos. 249749 and 248563
Tox Review No. 003042.

April 24, 1984. Notes. 12 Pages.
John Melone. HED.
Chuck Tricholo, Bill Burnam. Immediate Action.
See Ed's note. We discussed this at staff today.
Teratogenic Effects. Calculation of ADI and TMRC.
(Allowable Daily Intake; Theoretical Maximum Residue
Contribution).

May 23, 1985. Memorandum. 3 Pages.
R.W. Cook. Residue Chemistry Branch.
No Accession No. (RCB No. 828) PP #7E2007. Benomyl in
or on Peppers and Eggplants. An Update of RCB's Evaluation
of PP #7E2007 is Requested.

June 21, 1985. Memorandum. 3 Pages.
Philip Errico. Residue Chemistry Branch.
PP #0E2409. Benomyl Use on Garden Beets. Amendment of
July 19, 1982 (RCB #829) (No Accession No.).

October 11, 1985. Review. 11 Pages.
Jane Harris. Toxicology Branch.
3-Generation Reproduction (rat). Haskel Lab Study No. 264-68
Tox review 004708.

October 18, 1985. Memorandum. 4 Pages.
Sami Malak. Residue Chemistry Branch.
Review of Protocols for Benomyl Bound Liver Residues in
Response to 3(c)(2)(B) Data Call-In. No Accession Number.
RCB No. 1407.

October 24, 1985. Science Chapter. 169 Pages.
Marion Copley. Toxicology Branch.
Toxicology Branch Chapter of the Registration Standard
for Benomyl. Inert ingredient info on pages 6, 27, 63, 83-85
not included. MRIDs 66771, 66785, 97287, 66773, 97284,
115674, 96514, 88333, 97305, 81913, 97318, 97326, 61618.
Tox review 004679.

November 14, 1985. Memorandum. 12 Pages.
Gobind Makhijani. Residue Chemistry Branch.
Response to Data Gaps in the Product Chemistry Chapter
of the Benomyl Registration Standard.
Quality control procedure information on page 6 is not
included. Pages 7-12 are not included - quality control
procedure and manufacturing process information.

November 22, 1985. Memorandum. 3 Pages.
William Anthony. Residue Chemistry Branch.
Benomyl Sec. 18 on Potatoes in Florida. ID #86-FL-01.
RCB #157. Acc. No.: None.

January 24, 1986. Memorandum. 6 Pages.
Michael Firestone. Residue Chemistry Branch.
PP #6E3325 (RCB #310). Benomyl on Watercress. Evaluation
of Analytical Methods and Residue Data (Accession No.
074014).

January 30, 1986. Memorandum. 7 Pages.
Karl Arne. Residue Chemistry Branch.
Benomyl Cow Feeding and Metabolism Studies Submitted in
Response to a 3(c)(2)(b) Letter.

February 18, 1986. Memorandum. 1 Page.
Marion Copley. Toxicology Branch.
EPA Reg. No. 352-534. Historical control data from
chronic mouse studies, liver tumors.

March 11, 1986. Memorandum. 15 Pages.
Bertram Litt. Toxicology Branch.
Benomyl Risk Assessment Assumption for Q1* = 3.9 x 10^-3
for Carcinogenicity Potential.
Attachment(s) following:

February 14, 1986. Memorandum.
Bertram Litt. Toxicology Branch.
Interim Revised Estimate of Benomyl Cancer Potency.

March 26, 1986. Memorandum.
Bruce Jaeger. Toxicology Branch.
Definition and Use of the Term "MTD"
(Maximum Tolerated Dose).

April 22, 1986. Report.
Anonymous. Toxicology Branch.
Information Concerning Thiophanate Methyl for the
Scientific Advisory Panel.

*End of attachments*

March 25, 1986. Review. 19 Pages.
George Ghali. Toxicology Branch.
Reference Doses (RFDs) for Oral Exposure.
Carcinogenicity: Evidence of oncogenicity in mice,
no evidence in rats. Classified as a Category C oncogen.
Tox review 004785.

April 22, 1986. Review. 12 Pages.
None. No Affiliation.
Information Concerning Thiophanate Methyl for the Scientific
Advisory Panel.

April 22, 1986. Memorandum. 13 Pages.
Marion Copley. Toxicology Branch.
Executive Summary Concerning Benomyl for the Science
Advisory Panel. Tox Review 005111.

June 6, 1986. Memorandum. 8 Pages.
Frank Boyd. Residue Chemistry Branch.
PP #6E3361 - Benomyl on Potatoes (for South Florida,
Only) - Evaluation of Analytical Methods and Residue
Data - Accession No. 261143. RCB No. 584.

June 20, 1986. Memorandum. 6 Pages.
Sami Malak. Residue Chemistry Branch.
EPA Reg. No. 352-354. Benomyl; Protocol for Bound Liver
Residues. Letter of February 11, 1986. No Accession
Number. RCB No. 657.

July 22, 1986. Memorandum. 3 Pages.
Kenneth Dockter. Residue Chemistry Branch.
EPA Reg. No. 352-354. Benlate (Benomyl) Label Amendments
Dated 5/6/86 and 5/9/86 to Add Uses on Brussels Sprouts
and Turnip Greens. No Accession No. RCB Nos. 1134 and 1135.

February 19, 1987. Memorandum. 8 Pages.
Karl Arne. Residue Chemistry Branch.
Benomyl Processing Studies for Several Commodities
Submitted in Response to a 3(c)(2)(B) Letter.
RCB No. 675. Accession No. 261596.

March 5, 1987. Memorandum. 6 Pages.
Jesse Mayes. Residue Chemistry Branch.
PP #7E3467. RCB #1563. Acc. No. 265509. Benomyl in or
on Pistachios. Evaluation of Analytical Method and
Residue Data.

March 11, 1987. Memorandum. 3 Pages.
Leung Cheng. Residue Chemistry Branch.
87-CA-17. Proposed Section 18 Specific Exemption for Use
of Benomyl on Parsley. No Accession No. RCB #1987.

March 31, 1987. Memorandum. 1 Page.
R.W. Cook. Residue Chemistry Branch.
No Accession No. PP #7E2007. Benomyl in or on Bell Peppers
and Eggplants. Tox Response to RCB Dated 3/10/87.

April 13, 1987. Memorandum. 6 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 2792-LL. Peach, Nectarine, Plum Lustr 274.
Pages 5-6 are not included - draft label.

April 17, 1987. Memorandum. 2 Pages.
Nancy Dodd. Residue Chemistry Branch.
PP #7E3467 (RCB #2130). Benomyl in or on Pistachios.
Amendment Dated 3/13/87.

June 24, 1987. Memorandum. 15 Pages.
Jerry Stokes. Residue Chemistry Branch.
Benomyl Registration Standard. Response by DuPont
(Letter Dated 9/10/86) to the 3(c)(2)(B) Letter of 4/7/86.
(#352-354, RCB Nos. 1594, 2159).

August 26, 1987. Memorandum. 9 Pages.
Nancy Dodd. Residue Chemistry Branch.
PP #6E3361 (RCB No. 2153) - Benomyl on Potatoes (For South
Florida Only) - Amendment Dated December 9, 1986 -
Accession Nos. 400867-00 and 400867-01.

December 15, 1987. Memorandum. 3 Pages.
Francis Suhre. Residue Chemistry Branch.
Review of Benomyl GLP/Data Audit.
Record No. 208275. RCB No. 3064.

January 22, 1988. Memorandum. 2 Pages.
Leung Cheng. Residue Chemistry Branch.
88-FL-02. Section 18 Crisis Exemption. Benomyl on Cabbage.
No MRID No. RCB #3198.

April 7, 1989. Memorandum. 8 Pages.
John Quest. Science Analysis & Coordination Branch.
Third Peer Review of Benomyl/MBC.

May 3, 1989. Memorandum. 2 Pages.
Debra Edwards. Dietary Exposure Branch.
Anticipated Residues of MBC on Food and Feed Commodities
Resulting from Registered Use of Benomyl and
Thiophanate-methyl (RD Record No. 240751, HED Project
No. 9-0954, DEB No. 4991).

October 13, 1989. Review. 3 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
EPA Reg. No. 352-377
Anaerobic aquatic metabolism (162-3) study.

February 23, 1990. Review. 2 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
Review of soil column leaching and rice paddy
infiltration rate data in support of the aquatic field
dissipation data requirement
MRID 41274801.

February 23, 1990. Review. 20 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
Review of soil column leaching and rice paddy
infiltration rate data in support of the aquatic field
dissipation data requirement. Review of soil characteristics
info. in support of the mobility in soil data requirement.
MRID 41274801. Pages 6-13, 18-20 removed-registrant data.

February 27, 1990. Review. 242 Pages.
Marion Copley. Health Effects Division.
Peer Review Files; Benomyl (MBC).
Tox review 007710.
Attachment(s) following:

April 7, 1989. Memorandum.
John Quest. Science Analysis and Coordination Branch.
Third Peer Review of Benomyl/MBC.

March 31, 1986. Memorandum.
John Quest. Toxicology Branch.
Peer Review of Benomyl and MBC.

May 28, 1986. Memorandum.
Steven Johnson. FIFRA Scientific Advisory Panel OPP.
Transmittal of the Final FIFRA Scientific Advisory
Panel Reports on the May 21-22, 1986 Meeting.

May 15, 1989. Memorandum.
Bernice Fisher. Science Analysis and Coordination Branch.
MBC (INE-965) - Qualitative and Quantitative Risk
Assessment, CD-1 Mouse Study (Re-evaluation).

January 20, 1989. Memorandum.
Marion Copley. Toxicology Branch.
Weight-of-the-evidence and oncogenic properties of
Benomyl and MBC revisited: The third peer review.

March 11, 1986. Memorandum.
Bertram Litt. Toxicology Branch.
Benomyl Risk Assessment Assumption for Q1* = 3.9x10^-3
for Carcinogenicity Potency.

December 19, 1985. Memorandum.
Marion Copley. Toxicology Branch.
Follow-up to the Data Evaluation Report submitted
to the Tox. Br. Peer Review Panel.

May 1, 1982. Memorandum.
Bertram Litt. Toxicology Branch.
Statistical Evaluation and Oncogenicity Risk
Assessment of Benomyl, Benlate and MBC 2-Year
Feeding Studies in Mice.

October 3, 1985. Memorandum.
Reto Engler. Toxicology Branch.
Peer Review of Benomyl.

December 4, 1981. Memorandum.
Louis Kasza. Toxicology Branch.
Evaluation of Pathologic Data from
Two-Year Feeding Study in Mice
Treated with INE-965, MBC (Benomyl Metabolite).

*End of attachments*

March 13, 1990. Review. 1 Page.
Anna Skapar. Registration Support Branch.
EPA Reg. No. 352-377. Benomyl Technical.

August 24, 1990. Memorandum. 3 Pages.
Henry Nelson. Environmental Fate & Ground Water Branch.
The following is EFGWB's response to L. Rossi's August
14, 1990 memorandum to Hank Jacoby concerning the status of
environmental fate data requirements for benomyl:
MRIDs 41255801, 40158401, 41137710, 41291501, 259471,
00146415, 41274801,.

May 21, 1991. Analysis. 35 Pages.
Stephen Schaible. Science Analysis and Coordination Branch.
Dietary Exposure Analyses for the Proposed Uses of Benomyl
on Fresh Mint, Permethrin and Cyromazine in/on...
Information which is not responsive is not included
on pages 1 and 2. Pages 4-9 not included - not responsive.

July 12, 1991. Note. 3 Pages.
William Burnam. Toxicology Branch.
Chlorothalonil and Nustar (Flusilazole) Contamination of
Benomyl Formulations.

August 9, 1991. Memorandum. 8 Pages.
Richard Loranger. Chemistry Branch.
6(a)(2) Data on Contamination of Benomyl
[methyl 1-(butycarbamoyl)-2-benzimidazolecarbamate]
Products. CB #s 8204, 8273. DP Barcode 165858, 166182.
(No MRID #).

February 25, 1992. Note. 5 Pages.
Susanne Cerelli. Ecological Effects Branch.
Phytotoxicity Issues that were Published in the NY Times
and the Wall Street Journal concerning Benlate.

March 5, 1992. Review. 96 Pages.
Akiva Abramovitch. Environmental Fate & Ground Water Branch.
Review of aerobic soil, and anaerobic and aerobic aquatic
metabolism studies
MRID 41255801, 40158401, 41137701, 41291501
Pages 18-27, 32-41, 47-59 removed-registrant data.

March 9, 1992. Memorandum. 2 Pages.
Douglas J. Urban. Ecological Effects Branch.
Phytotoxicity Incidents Involving Benlate DF.

March 10, 1992. Memorandum. 2 Pages.
Douglas J. Urban. Ecological Effects Branch.
Phytotoxicity Incidents Involving Benlate DF.

April 15, 1992. Review. 3 Pages.
Douglas J. Urban. Ecological Effects Branch.
EEB Review of Benomyl - Benlate DF - Provide Footnote for
Required Plant Testing That was Indicated in a March 10,
1992 Memo from EEB to SRRD.

May 14, 1992. Review. 3 Pages.
Michael J. Clifford.
Revised CSF for Basic Formulation and Application for Two
Alternate Formulations in Water-Soluble Bags.
Manufacturing process information on page 1 is not included.
Inert ingredient information on pages 2 and 3 is
not included.

June 17, 1992. Memorandum. 10 Pages.
Melba Morrow. Toxicology Branch.
ID. No. 099101, 90 Day Inhalation Study in Rats with
Benomyl. (Guideline 82-4)
MRID 403995-01
Tox review 009540.

October 6, 1992. Review. 7 Pages.
Akiva Abramovitch. Environmental Fate & Ground Water Branch.
To review supplemental data to support an aerobic soil
metabolism study.

October 14, 1992. Review. 5 Pages.
Steve Knott. Occupational,Residential Exposure Branch.
Review of Benomyl Poisoning Incidents.

November 10, 1992. Memorandum. 6 Pages.
Douglas Urban. Ecological Effects Branch.
Review of Information from DuPont Regarding Benlate DF
Testing.

November 10, 1992. Review. 7 Pages.
Douglas J. Urban. Ecological Effects Branch.
EEB Review of Benomyl - Dupont - Review Information on
Adverse Effects Related to Benomyl.

December 8, 1992. Memorandum. 5 Pages.
Anthony Maciorowski. Ecological Effects Branch.
Review of Benomyl 50W 6 (a) (2) Literature.

February 18, 1993. Memorandum. 6 Pages.
Jerome Blondell. Occupational & Residential Exposure Bran.
Review of Benomyl poisoning incidents, Cases Submitted by
Dupont & Puerto Rico law suit.
MRID Nos. 422364-01, 426327-01 & -02.

March 24, 1993. Memorandum. 2 Pages.
Melba Morrow. Toxicology Branch.
ID. No. 099101, Benomyl, Information to Upgrade
Subchronic Inhalation Study.
Tox review 010115.

May 10, 1993. Memorandum. 6 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
Screen of Benomyl Incidents.

May 17, 1993. Review. 3 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
EEB Review of Benomyl - Fungicide - Dupont - Review Plant
Study Protocols.

June 15, 1993. DER. 6 Pages.
Mark Mossler. KBN Engineering for EEB.
Study Type: 71-1A. Avian Single Dose Oral LD50 Test.
Species Tested: Bobwhite quail.
MRID 15466701.

June 17, 1993. Review. 3 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
EEB Review of Benomyl - Fungicide - Dupont - Review Residue
Chemistry Analysis Results to Determine if Contaminants
Found in Benomyl Could Have Caused the Phytotoxicity
Incidents.

July 30, 1993. Review. 4 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
EEB Review of Benomyl - Dupont - Review Mode of Action
Information from Dupont Evaluate as it Pertains to Crop
Incidents Relating to Benomyl DF.

December 14, 1993. Review. 6 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
EEB Review of Benomyl - Dupont - Review 6A2 Adverse Effects
Data on Benomyl.

January 6, 1994. Memorandum. 6 Pages.
Jerome Blondell. Occupational & Residential Exposure Bran.
Review of Benomyl Data.
MRID Nos. 426493-01, 426885-00, 426886-00, 426879-00,
427178-00, 427441-00, 427632-01, 427943-01, & 428664-00, &
428822-00. Personal Privacy information removed from pages
3-5.

March 24, 1994. Review. 2 Pages.
Anthony F. Maciorowski. Ecological Effects Branch.
EEB Review of Benomyl - Fungicide - Dupont - Review 6A2
Data Related to Crop Damage Incidents Benomyl Including
DBU and BIC.

May 9, 1994. Memorandum. 150 Pages.
Anthony Maciorowski. Ecological Effects Branch.
Data Reviews for 72-3a and 72-3b with Carbendazim; Benomyl:
Acute toxicity tests with carbendazim.
MRID Nos. 409750-01 & -02. Registration Data removed from
pages 35-39, 48-51, 59-65, 80-85 & 138-142.

May 8, 1995. Memorandum. 2 Pages.
Jerome Blondell. Occupational & Residential Exposure Bran.
Review of law suits/800 number calls on Benomyl.
MRID No. 432028-00.

August 31, 1995. DER. 8 Pages.
Melba Morrow. Toxicology Branch I.
Developmental Toxicity Study in Rabbits; Developmental
Toxicity Study DPXT1991-529.
MRID No. 43788301.

January 5, 1997. Memorandum. 154 Pages.
Norman Cook. Ecological Effects Branch.
RED Science Chapter; Ecological Effects Branch Science
Chapter for benomyl; RED Document. MRID Nos. 44103001 & -02
43872801, 42817002, 43363401, 42817802, 42854802.
Registration Data removed from pages 68-72, 86-92, 103-107,
& 154.

December 3, 1997. Memorandum. 7 Pages.
Jess Rowland. Science Analysis Branch, HED.
BENOMYL - FQPA REQUIREMENT - Report of the Hazard
Identification Assessment Review Committee.

August 2, 1999. Memorandum. 23 Pages.
Deborah Smegal. Re-Registration Branch HED.
BENOMYL AND CARBENDAZIM- RE-EVALUATION - Report of the
Hazard Identification Assessment Review Committee.
This report supercedes the previous HIARC report dated
12/3/97; HED Doc No. 012418.
Tox review 013990.

October 26, 1999. Memorandum. 7 Pages.
Jerome Blondell. Chemistry & Exposure Branch I.
Review of Benomyl Incident Reports; DP Barcode 229878.

March 30, 2000. Memorandum. 63 Pages.
Deborah Smegal. Re-Registration Branch 3 HED.
Toxicology Chapter for Benomyl and Carbendazim. DP Barcode
D264602, Case 819338... This memorandum summarizes the guide
line studies... and other studies considered by HED in
developing the acute and chronic reference doses (RfD's) and
toxicity endpoints...
Attachment(s) following:

November 18, 1999. Memorandum.
Deborah Smegal. Re-Registration Branch 3 HED.
REVISED Benomyl/MBC Quantitative Risk Assessment (Q1*)
Based on CD-1 Mouse Dietary Study Using mg/kg
b.w.^3/4's/day Cross Species Scaling Factor.
Tox review 013859 and 014123.

*End of attachments*

March 20, 2001. Memorandum. 27 Pages.
Deborah Smegal. Re-Registration Branch HED.
BENOMYL AND CARBENDAZIM- Endpoint Selection for Incidental
Oral Ingestion for Carbendazim- 3rd Report of the Hazard
Identification Assessment Review Committee.
Tox review 014506.

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