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Index of Cleared Science Reviews for Vikane (Sulfuryl Fluoride) (Pc Code 078003)

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September 29, 1967. Review. 19 Page(s).
PD Baron. Toxicology Branch.
Trade name: Vikane Fumigant (page 2) Acute Rat Oral, Acute Guinea Pig Oral,
Acute Rat Feeding, Acute Rat Inhalation, Subacute Inhalation Tox review 002674.
Document (PDF) (523 KB PDF).

June 08, 1979. Memorandum. 7 Page(s).
Phyllis Johnson. Science Support Branch.
Transmission of RS Chemical Sulfuryl Fluoride FINAL Index Entry.
Document (PDF) (242 KB PDF).

October 16, 1979. Memorandum. 8 Page(s).
Ray Landolt. Toxicology Branch.
EPA Reg. No. 464-326 Vikane Fumigant Action requested: Add the following to the label
- 1) Fumigation for cockroaches... 2) Fumigation of dwellings Tox review 002673.
Document (PDF) (461 KB PDF).

February 05, 1982. Memorandum. 5 Page(s).
Gary Burin. Toxicology Branch.
Review of Rat and Rabbit Inhalation Teratology Studies of VIKANE
(Sulfuryl Fluoride) Acc. No. 246489 Tox review 001421.
Document (PDF) (269 KB PDF).

July 02, 1984. Memorandum. 10 Page(s).
M. I. Dow. Science Support Branch.
Sulfuryl Fluoride Qualitative Use Assessment.
Document (PDF) (639 KB PDF).

January 23, 1985. Memorandum. 3 Page(s).
Ken Clark. Ecological Effects Branch.
Registration Standard - Sulfuryl Fluoride 'Attached is a copy of EEB's Topical
Summary, Disciplinary Review and a Data Evaluation Record.'.
Document (PDF) (118 KB PDF).

February 08, 1985. Memorandum. 14 Page(s).
Ray Landolt. Toxicology Branch.
Sulfuryl Fluoride 'The Toxicology Chapter to the Registration Standard for Sulfuryl
Fluoride is enclosed.' Tox review 004281.
Document (PDF) (587 KB PDF).

January 22, 1986. Memorandum. 4 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg. No. 464-236 Protocol Review. Protocol Review.
Document (PDF) (187 KB PDF).

January 16, 1987. Review. 25 Page(s).
Joseph Reinert. Exposure Assessment Branch.
Reg. No. 464-236 Protocol Review. Pages 5-25 removed, registration data.
Document (PDF) (461 KB PDF).

November 10, 1987. Review. 2 Page(s).
Michael Firestone. Exposure Assessment Branch.
Reg. No. 464-236 Review of Exposure Studies.
Document (PDF) (200 KB PDF).

March 06, 1990. Review. 13 Page(s).
Elizabeth Haeberer. Dietary Exposure Branch.
DowElanco Response to Sulfuramyl Fluoride Reregistration Data Request
(MRID Nos. 413888-01 through -05, DEB No. 6426, HED Project No. 0-0801).
Pages 2-13 removed, draft label.
Document (PDF) (109 KB PDF).

August 24, 1990. Memorandum. 13 Page(s).
Irving Mauer. Toxicology Branch I.
Vikane Fumigant (sulfuryl fluoride) - Toxicology Data Submitted under
MRID No. 41448601 - ID No. 078003 - EPA Reg. No. 62719-4. Mouse Bone Marrow
Micronucleus Test. Pages 8-13 removed, registrant data. Tox review 008067.
Document (PDF) (381 KB PDF).

January 29, 1991. Memorandum. 10 Page(s).
Irving Mauer. Toxicology Branch.
Sulfuryl Fluoride - Toxicology Data Submitted Under MRID No. 416030-01
(Mutagenicity Study) Pages 9-10 removed, registration data. Tox review 008247.
Document (PDF) (420 KB PDF).

June 04, 1991. Memorandum. 8 Page(s).
Irving Mauer. Toxicology Branch.
VIKANE (Sulfuryl Fluoride) - Company Response Submitted Under
EPA MRID Nos. 417691-01 and 417691-02. Tox review 008392.
Document (PDF) (321 KB PDF).

November 26, 1991. Memorandum. 5 Page(s).
John Tice. Occupational & Residential Exposure Br.
Product Amendment Action for Sulfuryl Fluoride Fumigant (Vikane)
(EPA Reg. No 62719-4) MRID 418177-01, 403332-01.
Document (PDF) (305 KB PDF).

March 30, 1992. Memorandum. 14 Page(s).
Stanley Gross. Toxicology Branch.
Sulfuryl Fluoride (SF). 4 hour dermal vapor exposure study in rats.
MRID 417120-01. Tox review 009393. Pages 9-14 removed, registration data.
Document (PDF) (389 KB PDF).

April 13, 1992. Memorandum. 13 Page(s).
Kathy Monk. Environmental Fate & Effects Division.
Transmittal of EFED RED Chapters for Sulfuryl Fluoride
(Case #0176, Chemical #078003).
Document (PDF) (366 KB PDF).

April 13, 1992. Memorandum. 2 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Discussion EFGWB had concerns about two uses and their impact on the environment.
These were 1.)fumigation of large ocean-going vessels in ports and 2.)fumigation...
that involved moistening the soil with water.'.
Document (PDF) (85 KB PDF).

May 04, 1992. Memorandum. 66 Page(s).
Melba Morrow. Toxicology Branch.
ID No. 062719-00004, Two Generation Reproduction and Unscheduled DNA Synthesis
Studies with Sulfuryl Fluoride and misc. (inhalation) Data Reviews for the
RED MRID 421798-01, 408909-02, 408909-01, 408399-02. Tox Review 009479.
Pages 32-37, 49-51, & 62-66 removed, RD.
Document (PDF) (3074 KB PDF).

May 06, 1992. Memorandum. 7 Page(s).
Marion Copley. Health Effects Division.
Updated Toxicology Review for the Reregistration Eligibility Decision
Document on Sulfuryl Fluoride.
Document (PDF) (432 KB PDF).

May 18, 1992. Memorandum. 13 Page(s).
Linnea Hansen. Toxicology Branch I.
ID No. 062719-00004. Sulfuryl Fluoride, technical. Expedited review of 13-week
inhalation study in beagle dogs. MRID 422566-01. Tox review 009506.
Document (PDF) (643 KB PDF).

May 21, 1992. Memorandum. 27 Page(s).
Linnea Hansen. Toxicology Branch I.
ID No. 078003. Sulfuryl Fluoride, technical. Evaluation (Validation of Original
Review) of Rat and Rabbit Developmental Toxicity Studies Submitted to Support
Reregistration of Sulfuryl Fluoride. MRID 00090015. Tox review 009510.
Document (PDF) (1445 KB PDF).

July 28, 1992. Memorandum. 9 Page(s).
David Jaquith. Occupational & Residential Exposure Branch.
Evaluation of Preliminary Air Monitoring Data for Structural Fumigation
with Sulfuryl Fluoride.
Document (PDF) (301 KB PDF).

July 31, 1992. Memorandum. 2 Page(s).
Peg Perreault. Occupational & Residential Exposure Br.
Occupational and Residential Exposure Data Requirements for the Sulfuryl
Fluoride Data Call-In (DCI).
Document (PDF) (133 KB PDF).

September 14, 1992. Memorandum. 6 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID No. 078003. Review of Toxicology Data Base
to Determine Eligibility for Reregistration. Barcode No. : D180762.
Document (PDF) (340 KB PDF).

January 25, 1993. Memorandum. 2 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID #078003. Review of Study [protocol] for Evaluation of
Short-Term Inhalation Neurotoxicity in Rats (to Fulfill Guideline 81-8 Requirement).
DP Barcode: D186112.
Document (PDF) (177 KB PDF).

June 24, 1993. Memorandum. 16 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID# 078003. Evaluation of a Neurotoxicity Study on Short-Term
Inhalation Exposure of Rats, Performed According to a Modified Protocol for Guideline 81-8.
MRID 427720-01. Pages 12-16 removed, RD. Tox review 010363.
Document (PDF) (720 KB PDF).

August 06, 1993. Memorandum. 17 Page(s).
Nguyen Thoa. Chemical Coordination Branch.
The HED Chapter of the Reregistration Eligibility Document (RED) for Sulfuryl
Fluoride, Case # 0176 (Pesticide Chemical Code 078003). Tox review 010472.
Document (PDF) (1121 KB PDF).

January 27, 1994. Memorandum. 2 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID 078003. Review of a Protocol for a rat 2-Year Chronic
Toxicity/Oncogenicity Study, Including Neurotoxicity Testing to Satisfy Guideline
82-5 (Subchronic Neurotoxicity Testing in Rat). Barcode No.: D196192.
Document (PDF) (129 KB PDF).

February 02, 1994. Memorandum. 10 Page(s).
Linnea Hansen. Toxicology Branch I.
ID# 078003. Sulfuryl Fluoride. Evaluation of Motor Activity Validation & Functional
Observational Battery Proficiency Testing Studies Submitted by Dow Chemical Co...
MRID 428562-01, 02. TXR 010757. Pages. 7-10 removed, registrant data.
Document (PDF) (447 KB PDF).

June 08, 1994. Memorandum. 2 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID NO. 078003. Chronic Neurotoxicity Study in Rat.
[6(a)(2) data, MRID 432167-02].
Document (PDF) (90 KB PDF).

May 01, 1995. Memorandum. 2 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID 078003. Response to 6(a)(2) Submission for Chronic
Toxicity/Neurotoxicity/Carcinogenicity Data. MRID 433549-01, 02, 03, 432167-02.
DP Barcode Nos.: D204025, D210874.
Document (PDF) (154 KB PDF).

August 30, 1995. Memorandum. 14 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID 078003. Evaluation of 90-Day Mouse Inhalation Toxicity Study.
MRID 43129401. Product impurity info on page 4 not included Tox review 011648.
DP Barcode No. D199879.
Document (PDF) (282 KB PDF).

May 23, 1997. Review. 6 Page(s).
David Jaquith. Chemical Exposure Branch II.
Non-Dietary Exposure Review; Re-Validation of Air Monitoring for Sulfuryl Fluoride.
DP Barcode: D227297.
Document (PDF) (237 KB PDF).

October 29, 1997. Review. 20 Page(s).
David Jaquith. Chemical Exposure Branch II.
Non-Dietary Exposure Review; Evaluation of Miran & Interscan for Monitoring Air
Concentrations of Sulfuryl Fluoride. MRID No. 43836-01. DP Barcode: D227291.
Document (PDF) (771 KB PDF).

February 02, 1998. Memorandum. 88 Page(s).
Linnea Hansen. Toxicology Branch I.
Sulfuryl Fluoride. ID # 078003. Evaluation of Rat Chronic Toxicity/Oncogenicity,
Dog Chronic Toxicity and Mouse Oncogenicity Inhalation Studies.
MRID 43354901, 02, 03. Impurity info on page 9 deleted. TXR 012468.
DP Barcode Nos.: D210874, D226103, D227298.
Document (PDF) (4411 KB PDF).

April 09, 2001. DER. 18 Page(s).
Edwin Budd. Registration Action Branch.
STUDY TYPE: 2-Week Subchronic Inhalation Study, Rabbits.
Pages 16-18 removed, registrant data. MRID 148956.
From Tox review 014618, page 42, R028267.
Document (PDF) (636 KB PDF).

May 15, 2001. Memorandum. 2 Page(s).
Becky Daiss. Reregistration Branch 4 HED.
Sulfuryl Fluoride (078003) Residential Risk from Dissipation of Sulfuryl Fluoride
after Structural Fumigation (62719-EUP- -45) DP Barcode No. 274960 MRID No. none.
Document (PDF) (115 KB PDF).

June 11, 2002. Memorandum. 23 Page(s).
Michael Doherty. Registration Action Branch HED.
PP# 1F6312. Sulfuryl Fluoride in/on Cereal Grain Commodities Request
for Tolerance Method Validation. MRIDs 45603901, 45632901, 45632902.
Document (PDF) (696 KB PDF).

October 31, 2003. Memorandum. 32 Page(s).
Jessica Kidwell. Health Effects Division.
SULFLURYL FLUORIDE - Second Report of Hazard Identification Assessment Review Committee.
OPP-2003-0373. Tox review 0052208.
Document (PDF) (1904 KB PDF).

January 13, 2004. Memorandum. 45 Page(s).
Michael Doherty. Registration Action Branch.
Chronic Dietary Exposure Assessments for Sulfuryl Fluoride and Fluoride Anion,
Addressing the Section 3 Registration of Sulfuryl Fluoride on Stored Cereal Grains,
Grain Processing Facilities, Dried Fruits, and Tree Nuts. PP1F6312. DP Barcode: D283008.
Document (PDF) (1729 KB PDF).

January 13, 2004. Memorandum. 91 Page(s).
Michael Doherty. Registration Action Branch.
PP#1F06312 - Sulfuryl Fluoride. Section 3 Registration for the Post-harvest Fumigation of
Stored Cereal Grains, Dried Fruits, & Tree Nuts, & Fumigation of Grain Milling Establishments…
Document (PDF) (3275 KB PDF).
Attachment(s) Following:

January 13, 2004. Memorandum.
Michael Doherty. Registration Action Branch.
(Continued) DP Barcode: D283007. MRID Nos.: 45396301, 45510302,
45510303, 45510304, 45603901, 45632901, 45632902.

*End of Attachments*

April 22, 2004. Memorandum. 2 Page(s).
Vicki L. Dellarco. Health Effects Division.
Waiver Justification of Inhalation Rat Developmental Neurotoxicity Study With
Sulfuryl Fluoride. (justification submitted by Dow).
Document (PDF) (64 KB PDF).

October 12, 2004. Memorandum. 21 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
PP#1F06312 - Sulfuryl Fluoride. Section 3 Registration for the Post-harvest
Fumigation of Stored Cereal Grains, Dried Fruits, & Tree Nuts, & Fumigation of Grain
Milling Establishments. Corrected Summary of Analytical Chemistry & Residue Data.
DP # 309015.
Document (PDF) (1148 KB PDF).
Attachment(s) Following:

October 12, 2004. Memorandum.
Michael Doherty. Reregistration Action Branch 2 HED.
continued. MRID MRID Nos.: 45396301, 45510302, 45510302, 45510303, 45510304,
45603901, 45632902. NOTE: This... corrects errors in the original summary
document addressing petition 1F06312 (M. Doherty, 1/13/04).

*End of Attachments*

October 12, 2004. Memorandum. 40 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
PP#1F06312 - Sulfuryl Fluoride. Section 3 Registration for the Post-harvest
Fumigation of Stored Cereal Grains, Dried Fruits, & Tree Nuts, & Fumigation of Grain
Milling Establishments. Corrected Summary of Analytical Chemistry & Residue Data.
DP # 309015.
Document (PDF) (1664 KB PDF).
Attachment(s) Following:

October 12, 2004. Memorandum.
Michael Doherty. Reregistration Action Branch 2 HED.
(continued) MRID Nos.: 45396301, 45510302, 45510302, 45510303, 45510304,
45603901, 45632902. NOTE: corrects errors in M. Doherty, 1/13/04.

*End of Attachments*

October 12, 2004. Memorandum. 45 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
Corrected Chronic Dietary Exposure Assessments for Sulfuryl Fluoride & Fluoride Anion,
Addressing the Section 3 Registration of Sulfuryl Fluoride on Stored Cereal Grains,
Grain Processing Facilities,...PP# 1F6312. DP # 309014. (corrects D283008, 1/13/04).
Document (PDF) (2300 KB PDF).

October 12, 2004. Memorandum. 51 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
Corrected Human Health Risk Assessment for Sulfuryl Fluoride and Fluoride Anion
Addressing the Section 3 Registration of Sulfuryl Fluoride Post-Harvest Fumigation
of Stored Cereal Grains, Dried Fruits and Tree Nuts...PP# 1F6312. DP Number: 309013.
Document (PDF) (2903 KB PDF).
Attachment(s) Following:

October 12, 2004. Memorandum.
Michael Doherty. Reregistration Action Branch 2 HED.
continued. NOTE: This assessment is being issued to correct errors
in the original assessment (D275199, M. Doherty, 1/20/2004).

*End of Attachments*

July 13, 2005. Memorandum. 16 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
Sulfuryl Fluoride. Evaluation of the Proposed Fumigation of Food Processing Establishments.
Summary of Analytical Chemistry and Residue Data. Petition Number 3F6573.
DP Number 317730. MRID 45899201.
Document (PDF) (803 KB PDF).

July 13, 2005. Memorandum. 35 Page(s).
Michael Doherty. Registration Action Branch.
Sulfuryl Fluoride. Evaluation of the Proposed Fumigation of Food Processing Establishments.
Summary of Analytical Chemistry and Residue Data. Petition Number 3F6573.
DP Number 317730. MRID 45899201.
Document (PDF) (2066 KB PDF).

July 13, 2005. Memorandum. 4 Page(s).
Michael Doherty. Registration Action Branch.
HED Resonse to Comments Received Regarding the Notice of Filing for Petition 3F6573
- Use of Sulfuryl Fluoride in Food Processing Facilities. DP Number: D316783.
Document (PDF) (152 KB PDF).

January 18, 2006. Memorandum. 40 Page(s).
Michael Doherty. Registration Action Branch HED.
Human Health Risk Assessment for Sulfuryl Fluoride and Fluoride Anion Addressing
the Section 3 Registration of Sulfuryl Fluoride as a Fumigant for Foods and Food
Processing Facilities. PP# 3F6573. DP Number: D312659. OPP-2005-0174.
Document (PDF) (1676 KB PDF).

January 18, 2006. Memorandum. 43 Page(s).
Michael Doherty. Reregistration Action Branch 2 HED.
Sulfuryl Fluoride and Fluoride Chronic Dietary Exposure Assessments for the
Section 3 Registration of Sulfuryl Fluoride as a Fumigant for Various Foods
and Food Processing Facilities. DP Code: 317731.
Document (PDF) (2017 KB PDF).

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