![[logo] US EPA](../gif/logo_epaseal.gif){kind=logo}
Index of Cleared Science Reviews for Metaflumizone (Pc Code 281250)
You will need Adobe Reader to view some of the files on this page. See EPA's PDF page
Undated. DER. 5 Page(s).
Byron Backus. Technical Review Branch.
METAFLUMIZONE and AMITRAZ NONGUIDELINE
STUDY TYPE: DERMAL PENETRATION PHARMACOKINETICS.
Pharmacokinetics Following Dermal Application [Canine] Nonguideline. TXR#: 0053824.
DP BARCODE: D322975. MRID No. 46672101.
Document (105 KB PDF).
January 25, 2004. Review. 6 Page(s).
John Hebert. Registration Division.
Efficacy Review File Symbol: 80490-G DP Barcode: D314412 Efficacy [fleas]
of spot-on treatment for cats and kittens. MRIDs 46437609 thru -14.
Document (252 KB PDF).
December 29, 2004. Memorandum. 17 Page(s).
Eugenia McAndrew. Technical Review Branch.
Name of Pesticide Product: Promeris Spot On for Dogs.
EPA Reg. No. /File Symbol: 80490-E. DP Barcode: D311471.
Decision No: 351841 PC Codes: 106201, 281251/281250.
MRID Nos. 463958-05 through -10.
Document (651 KB PDF).
May 27, 2005. Memorandum. 72 Page(s).
Byron Backus. Technical Review Branch.
EPA File Symbol: 80490-E Promeris Spot-On for Dogs DP Barcode: D311482
two companion animal safety studies MRID 46401003, 46401004.
Document (4658 KB PDF).
June 10, 2005. Memorandum. 19 Page(s).
Byron Backus. Technical Review Branch.
EPA File Symbol: 80490-G Promeris Spot-On for Cats DP Barcode: D314411
Decision No.: 354816 PC Code: 281250 (Metaflumizone, R-28153, BAS 320 I)
acute tox studies. MRID 46437603 thru -08.
Document (1688 KB PDF).
September 16, 2005. Memorandum. 41 Page(s).
Byron Backus. Technical Review Branch.
EPA File Symbol: 80490-E Promeris Spot-On for Dogs DP Barcode: D319379
The registrant has responded to a previous TRB review (dated 27 May 2005, D311482).
Pages 24-27 removed, registrant data. MRID 46401003, -04.
Document (1607 KB PDF).
October 03, 2005. Memorandum. 34 Page(s).
Byron Backus. Technical Review Branch.
EPA File Symbol: 80490-G Promeris Spot On for Cats DP Barcode: D314413
animal safety data MRIDs 46437615 and 46437616.
Document (4873 KB PDF).
April 19, 2006. Efficacy Review. 10 Page(s).
John Hebert. Registration Division.
File Symbol: PROMERIS SPOT ON FOR DOGS. EPA File Symbol 80490-E.
DP BARCODE: D311483. Purpose: Provide efficacy data to support product
registration of a spot-on for control of fleas and ticks on dogs and
puppies over eight weeks of age.
Document (448 KB PDF).
Attachment(s) Following:
April 19, 2006. Efficacy Review. 10 Page(s).
John Hebert. Registration Division.
(Continued)…MRID Nos. 463965813, 46395814, 46395815,
46395816, 46395817, 46395818, 46395819, 46395820.
*End of Attachments*
August 21, 2006. Memorandum. 3 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: Promeris Spot-On for Dogs
EPA Reg. No./File Symbol: 80490-E DP Barcode: D331545 summary data;
Australia's review of Promeris (MRID 46401004).
Document (227 KB PDF).
August 21, 2006. Memorandum. 52 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: Promeris Spot-On for Dogs
EPA Reg. No./File Symbol: 80490-E DP Barcode: D327884
additional dog studies to address toxicity concerns
MRID 46672102, -03, -04.
Document (2667 KB PDF).
August 21, 2006. Memorandum. 8 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: Promeris Spot-On for Dogs
EPA Reg. No./File Symbol: 80490-E DP Barcode: D327883
pharmacokinetic study in dog.
MRID 46672101.
Document (732 KB PDF).
November 13, 2006. Memorandum. 3 Page(s).
Rosalind Gross. Technical Review Branch.
CHILD-RESISTANT PACKAGING REVIEW. EPA Reg. No. or File Symbol 80490-G.
Examine data for 2 CRP tests to ascertain if CRP is acceptable for 0,8ml
Cat Product and...Reg. No. 80490-E Dog Product for 1.6ml Cat Product.
DP Barcode 332604. MRID No. 469217-01,-02.
Document (155 KB PDF).
November 30, 2006. Memorandum. 3 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: Promeris Spot-On for Dogs
EPA Reg. No./File Symbol: 80490-E DP Barcode: D332930
Fort Dodge's response (submitted 7/6/05; reference EPA
letter dated 27 May 2005...).
Document (168 KB PDF).
February 20, 2007. Memorandum. 8 Page(s).
Rosalind Gross. Technical Review Branch.
CHILD-RESISTANT PACKAGING REVIEW. EPA Reg. No. or File Symbol 80490-E.
Examine data for 8 CRP tests (test data for 4 pipette sizes) to ascertain
if CRP is acceptable...EPA Reg. No. 80490-E...DP Barcode 332603.
MRID Nos. 469217-00,469217-03 to 09.
Document (409 KB PDF).
March 31, 2008. Memorandum. 34 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: PROMERIS SPOT ON FOR DOGS.
EPA Reg. No. /File Symbol: 80490-2. DP Barcode: D348052.
MRID Nos. 47303301-47295301.
Document (1713 KB PDF).
December 02, 2008. Efficacy Review. 10 Pages.
Kable Bo Davis. EPA/OPP.
EFFICACY REVIEW. PRODUCT: ProMeris for Dogs. REG NUMBER: 80490-2.
DB BARCODE: D357599. DECISION: 400894. Review data to determine if it
supports claims for (1) that the kill...as an alternative applications site.
MRID Nos. 475693-01 thru -05, 47557806.
Document (543 KB PDF).
December 17, 2008. Efficacy Review. 2 Pages.
Kable Bo Davis. EPA/OPP.
EFFICACY REVIEW. PRODUCT: ProMeris for Dogs. REG NUMBER: 80490-2.
DB BARCODE: D359470. DECISION: 400894. To respond to rebuttal of
Agency review dated December 2, 2008 (D357599).
MRID Nos. 475693-01 thru -05, 47557806.
Document (53 KB PDF).