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Index of Cleared Science Reviews
Index for Procymidone (PC Code 129044)
Undated. Memorandum. 5 Pages.
Allen Jennings. Biological and Economic Analysis Div.
Procymidone-Wine Economics.
July 30, 1990. Memorandum. 32 Pages.
Stephanie Willett. Dietary Exposure Branch.
PP No. 0E3859. Procymidone (New Chemical) on Imported
Wine Grapes. Evaluation of Analytical Method and Residue
Data. MRID Nos. 414849-00, 414777-01, -11, -12, -13,
414688-18 thru -31, 414849-07. Manuf. process info page 8
removed. Pages 30-32 not included-csf and manuf process info.
August 29, 1990. Memorandum. 388 Pages.
K. Clark Swentzel. Toxicology Branch II.
Procymidone: Review of Toxicity Studies Submitted to Support
the Safety of Residue in Imported Wines
MRIDs 414688-01 to -17; 414849-01 to -06; 414777-02 to -10.
Tox review 008074 (continued).
Attachment(s) following:
August 29, 1990. Memorandum.
K. Clark Swentzel. Toxicology Branch II.
Pages 60-64, 77-84, 97-106, 114-115, 138-151, 159-168,
176-177, 198-209, 217, 232, 240-257, 264-267,
286-291, 298-302, 313-314, 319-322 removed, registrant data.
*End of attachments*
October 13, 1990. Memorandum. 7 Pages.
Allen Jennings. Biological and Economic Analysis Div.
Update on Procymidone/Wine Economics.
November 28, 1990. Data Eval. Rec. 13 Pages.
Stephen Dapson. Toxicology Branch.
Teratology - Developmental Toxicity; Rat; Guideline 83-3
MRID 416549-01. Pages 7-11 removed, registrant data.
Tox review 008180.
December 5, 1990. Memorandum. 30 Pages.
Stephen Dapson. Toxicology Branch.
Review Pilot Teratology Study in Rats with Procymidone
and additional data (substance intake data) from the
Rat Reproduction Study with Procymidone. EPA ID No.
0E03859, Caswell No. 704J, HED Project No. 1-0041A.
Tox #8180.
June 24, 1991. Memorandum. 12 Pages.
Stephen Dapson. Toxicology Branch II.
Review of Range-Finding and Primary Teratology Study
Protocols in Rats with Procymidone.
June 27, 1991. Memorandum. 44 Pages.
Stephanie Willett. Chemistry Branch.
PP No. 0E3859. Procymidone on Imported Wine Grapes.
Evaluation of Study Protocols and Response to CBTS
Deficiencies. MRID Nos. 416549-02, -03, -04, 417232-00,
-01, 417609-00, 417609-01.
July 12, 1991. Memorandum. 13 Pages.
K. Clark Swentzel. Toxicology Branch II.
Procymidone - Salmonella typhimurium/Mammalian
Microsome Mutagenicity Assay and Test Protocol for
a Chronic Toxicity Study in Dogs
MRID 418385-07
Tox review 008456.
August 5, 1991. Memorandum. 4 Pages.
Stephanie Willett. Chemistry Branch.
PP No. 0E3859. Procymidone on Imported Wine Grapes.
Evaluation on Supplemental Information on Physical and
Chemical Properties. MRID Nos. 418385-01 thru -05, -08,
419144-01.
August 9, 1991. Memorandum. 3 Pages.
Stephen Dapson. Chemistry Branch II.
Review of a Range-Finding Teratology Study Protocol in
Rats with Procymidone.
November 19, 1991. Memorandum. 22 Pages.
K. Clark Swentzel. Chemistry Branch II.
Procymidone(Sumilex)--A UDS assay in primary rat
hepatocytes and an in vitro chromosome aberrations study
in Chinese hamster ovary (CHO) cells.
Tox review 008849.
December 3, 1991. Memorandum. 8 Pages.
Stephanie Willett. Chemistry Branch I.
PP No. 0E3859. Procymidone on Imported Wine Grapes.
Partial Response to CBTS Memo dated 7/30/90. MRID Nos.
419603-00, -01.
December 18, 1991. Memorandum. 5 Pages.
Stephanie Willett. Chemistry Branch I.
PP No. 0E3859. Procymidone on Imported Wine Grapes. CBTS
Response to Petitioner's Requuest for a Waiver of Animal
Metabolism and Livestock Feeding Studies. MRID Nos.
420474-00, -01.
February 10, 1992. Memorandum. 3 Pages.
Alfred Smith. Registration Support Branch.
Results of the Method Trails for the Active Ingredient
Procymidone.
Attachment(s) following:
January 29, 1992. Memorandum.
Gregory Verdin. Analytical Chemistry BRanch.
Analytical Procedure for the Determination of Sumilex
... content in procymidone technical grade materials
and S-7131 W.P. formulations.
*End of attachments*
February 18, 1992. Memorandum. 1 Page.
Stephen Dapson. Toxicology Branch II.
Review of a Primary Teratology Study Protocol in Rats
with Procymidone.
April 7, 1992. Memorandum. 11 Pages.
Stephanie Willett. Toxicology Branch II.
PP No. 0E3859. Procymidone on Imported Wine Grapes. CBTS
Review of Grape Metabolism Studies. MRID Nos. 420420-00,
-01, -02.
June 24, 1992. Memorandum. 2 Pages.
Alan Levy. Toxicology Branch II.
PROCYMIDONE (Sumilex) - Purity and Stability in a 6-Month
dog Study (MRID No.: 414849-04)
Tox review 009550.
October 3, 1992. Memorandum. 17 Pages.
Stephen Dapson. Toxicology Branch II.
PROCYMIDONE - Review additional data for the
Multigeneration Reproduction Study in the Rat.
EPA DP Barcode D164557, Submission No. S396379, MRID No.
417779-01...
Tox review 009778.
November 4, 1992. Data Eval. Rec. 26 Pages.
Timothy McMahon. Toxicology Branch II.
Metabolism (85-1) (Metabolism in the Rat)
MRID 423856-01
Tox review 009841.
November 9, 1992. Data Eval. Rec. 9 Pages.
Kristin Jacobson. Clement International Corporation.
Procymidone
Mutagenicity: Acute Dose Range-finding Study/
Micronucleus Assay with Mice
DOC 930219.
November 9, 1992. Data Eval. Rec. 9 Pages.
Kristin Jacobson. Clement International Corporation.
Procymidone
Mutagenicity: Salmonella typhimurium/Escherichia coli/
Mammalian Microsome Preincubation Mutagenicity Assay
DOC 930218.
November 18, 1992. Memorandum. 15 Pages.
Timothy McMahon. Toxicology Branch II.
cis- 1,2-dimethylcyclopropane; CCA
Review of a rat metabolism study with CCA.
MRID 424221-01
Tox review 009827.
November 25, 1992. Memorandum. 28 Pages.
Timothy McMahon. Toxicology Branch II.
N - (3,5-dichlorophenyl) - 1,2-dimethylcyclopropane - 1,2 -
dicarboximide (Procymidone). MRID 423856-01.
Review of a rat metabolism study with procymidone
Subdivision F guideline 85-1.
Tox review 009841.
November 25, 1992. Memorandum. 2 Pages.
Timothy McMahon. Toxicology Branch II.
N - (3,5-dichlorophenyl) - 1,2 - dimethylcyclopropane - 1,2-
dicarboximide (Procymidone)
MRID 423856-01
Tox review 009841.
December 22, 1992. Memorandum. 7 Pages.
K. Clark Swentzel. Toxicology Branch II.
Procymidone Mutagenicity Studies
UDS Assay in Rat Hepatocytes
MRID 423726-01, 423726-02.
March 1, 1993. Memorandum. 25 Pages.
Stephen Dapson. Toxicology Branch II.
PROCYMIDONE - Review of a developmental toxicity study
in the rat with a post-natal segment. . .
MRID No. 423834-01, 423834-02 and 424820-02.
Tox review 010048.
March 22, 1993. Memorandum. 14 Pages.
K. Clark Swentzel. Toxicology Branch II.
Procymidone(Sumilex)--Chronic Feeding Study in Dogs
MRID Nos. 425750-01.
June 14, 1993. Memorandum. 6 Pages.
K. Clark Swentzel. Toxicology Branch II.
Procymidone(Sumilex)--Registrant's Updated Risk Assessment
MRID Nos. 426155-01.
June 16, 1993. Memorandum. 52 Pages.
Stephanie Willett. Health Effects Division.
PP No. 0E03859. Procymidone on Imported Wine Grapes.
CBTS Review of Wine, Ruminant, and Poultry Metabolism
Studies. CB Nos...
MRID 424627-01, 424820-01, 425750-02.
Attachment(s) following:
April 7, 1992. Memorandum.
Stephanie Willett. Chemistry Branch.
PP No. 0E03859. Procymidone on Imported Wine Grapes. CBTS
Review of Grape Metabolism Studies. MRID Nos. 420420-00,
-01, -02. HED Project No...
May 27, 1993. Memorandum.
Stephanie Willett. Chemistry Branch.
PP No. 0E03859. Procymidone on Imported Wine/Grapes.
Outcome of 5/19/93 HED Metabolism Committee Meeting.
*End of attachments*
October 29, 1993. Memorandum. 36 Pages.
Michael Flood. Chemistry Branch.
PP#0E3859. Procymidone on Imported Wine Grapes.
Additional Residue Data. Storage Stability Data. Inerts.
MRID #'s 424508-01, -02; 426028-01; 426096-01; 426099-01;
427400-01, -02. Commercial/financial info on pages 2 and 4
is not included. Pages 35-36 removed-inert ingredient info.
March 3, 1994. Memorandum. 122 Pages.
Stephanie Willett. Chemical Coordination Branch.
PP No. 0E3859. Procymidone in Wine Grapes. HED Assessment
of Human Risk. PC No. 129044. DP No. 190371.
Pages 64-65 removed, inert ingredient information.
Attachment(s) following:
April 5, 1991. Memorandum.
James Rowe. Toxicology Branch.
Peer review of Procymidone: consideration of Science
Advisory Panel recomendations.
July 8, 1993. Memorandum.
Stephen Dapson. Toxicology Branch.
Developmental and Reproductive Toxicity Peer Review of
Procymidone.
November 10, 1993. Memorandum.
George Ghali. Health effects Division.
Procymidone: RfD/Peer Review Report.
October 29, 1993. Memorandum.
Michael Flood. Chemistry Branch.
PP#0E3859. Procymidone on Imported Wine Grapes.
Additional Residue Data. Storage Stability Data.
Inerts.
June 1, 1993. Review.
Dynamac Corporation. Chemistry Branch.
Task 4. PP#0E3859
MRIDs 42450801, 42450802.
October 18, 1993. Review.
anonymous. Chemistry Branch.
Procymidone RAD meeting - October 18, 1993
HED Position.
Undated. Review.
anonymous. Chemistry Branch.
International Residue Limit Status.
February 14, 1991. FR Notice.
Douglas Campt. Office of Pesticide Programs.
40 CFR Part 180
[OPP-300225B; FRL-3880-6]
Pesticide Tolerances for Procymidone; Reissuance of Proposal.
October 1, 1992. Report.
Food and Drug Administration.
FDA Pesticide Program
Residue Monitoring 1991.
This is the fifth annual report summarizing the results
of pesticide residue monitoring...
February 14, 1994. Memorandum.
Reto Engler. Health Effect Division.
Risk Assessment for "Chloranalines" and Other
Carcinogenic metabolites Tox. Chem No 182.
February 24, 1994. Memorandum.
Michael Flood. Chemistry Branch.
PP#0E3859 - Procymidone in/on Wine Grapes. Sumitomo
Chemical Co., Ltd. Amendments Dated 1/3/94 and 1/24/94.
Chilean Residue Data. Use labels for South America.
*End of attachments*