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Index of Cleared Science Reviews

Index for Myclobutanil (Pc Code 128857)

January 2, 1985. DER. 6 Pages.
Robert Pilsucki. Ecological Effects Branch.
Acute 48-hour LC50 for Daphnia magna.
Pages 5-6 removed, registrant data.
Acc. No 072894.

January 2, 1985. DER. 7 Pages.
Robert Pilsucki. Ecological Effects Branch.
Acute 96-hour LC50 for bluegill sunfish
Pages 6-7 removed, registrant data.
Acc. No 072894.

January 2, 1985. DER. 7 Pages.
Robert Pilsucki. Ecological Effects Branch.
Acute 96-hour LC50 for rainbow trout.
Pages 6-7 removed, registrant data.
Acc. No. 072894.

January 2, 1985. DER. 8 Pages.
Robert Pilsucki. Ecological Effects Branch.
Dietary LC50 for mallard ducks.
Pages 6-8 removed, registrant data.
Acc. No. 072894.

January 2, 1985. DER. 8 Pages.
Robert Pilsucki. Ecological Effects Branch.
Dietary LC50 in bobwhite quail.
Pages 6-8 removed, registrant data.
Acc. No. 072894.

January 4, 1985. Review. 2 Pages.
Samuel Creeger. Exposure Assessment Branch.
File Nos. 707-EUP-RNL and -RNU. RH-3866 Fungicide.
EUP: Use on Apples, Wheat and Grapes.

March 26, 1985. Review. 5 Pages.
Samuel Creeger. Exposure Assessment Branch.
File Nos. 707-EUP-RNL and -RNU. RH-3866 40W. EUP: New
Chemical Use on Apples, Wheat and Grapes.
Attachment(s) following:

March 19, 1985. Final Report. 21 Pages.
Dynamac Corporation. Dynamac Corporation.
RH-3866.
Task 1: Review and Evaluation of Individual Studies.
Task 2: Environmental Fate and Exposure Assessment.

*End of attachments*

September 11, 1985. Review. 4 Pages.
Emil Regelman. Exposure Assessment Branch.
File No. 707-EUP-RNL. RH-3866.
EUP for Use on Grapes, Apples and Turf Grain.

September 18, 1985. Final Report. 13 Pages.
Dynamac Corporation. Dynamac Corporation.
RH-3866.
Task 1: Review and Evaluation of Individual Studies.
Task 2: Environmental Fate and Exposure Assessment.

February 10, 1986. Memorandum. 29 Pages.
Jane Harris. Toxicology Branch.
Systhane or Myclobutanil (RH-53,866 or RH-3866)
Acc. Nos 073522, 073805, 073806, 073807
Pages 10-29 removed, registrant data.
Tox review 004936.

February 11, 1986. Memorandum. 252 Pages.
Jane Harris. Toxicology Branch.
RH-3866 2E Fungicide (EPA #707-EUP-RNU)...
Pages 8, 23-58, 68-83, 91-96, 107-133, 169-195, 219-220 and
235-236 removed, registrant data. Inert ingredient info
on page 224 is not included.
Tox review 004937.

March 5, 1986. Review. 12 Pages.
Emil Regelman. Exposure Assessment Branch.
File Nos. 707-EUP-RNL. RH-3866.
Clarification of Several Issues, and New Information to
Satisfy EUP Requirements for Apples, Grapes and Perennial
Grasses for Seed.
Pages 5-12 removed, registrant data.

December 17, 1986. Review. 3 Pages.
Emil Regelman. Exposure Assessment Branch.
File Nos. 707-ERE, -ERN, -ERR. Rally. New Chemical
Screen - Submission of Data in Support of Registration on
Apples and Grapes.

January 6, 1987. Memorandum. 11 Pages.
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 707-ERE (1)
Rally 40W Fungicide
Pages 7-11 removed, draft label.
Tox review 006370.

January 13, 1987. Memorandum. 4 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
Rally 60DF Fungicide
EPA File Symbol 707-EUP-RRG
Page 4 removed, draft label.
Tox review 006371.

January 13, 1987. Memorandum. 3 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
Rally 60DF Fungicide
EPA File Symbol 707-EUP-RRG
Tox review 005846.

April 22, 1987. Memorandum. 17 Pages.
Pamela Hurley. Toxicology Branch.
707-EUP-RRG/7G3479/7H5523. RH-3866 (Rally)
Fungicide. Petition for Temporary Tolerances...
Pages 8-9 removed, draft label. Pages 15-17 removed,
registrant data.
Tox review 005845.

May 15, 1987. Data Eval. Rec. 3 Pages.
J. Jordan. Exposure Assessment Branch.
Myclobutanil. Laboratory leaching study of 1,2,4-triazole
aged residues through soil columns. Acc. No. 265748.

May 15, 1987. Data Eval. Rec. 3 Pages.
J. Jordan. Exposure Assessment Branch.
Myclobutanil. RH-3866 soil residue decline study.
Acc. No. 265749.

May 15, 1987. Data Eval. Rec. 1 Page.
J. Jordan. Exposure Assessment Branch.
Myclobutanil. Addendum to RH-3866 soil metabolism study.
Acc. No. 265747.

May 15, 1987. Data Eval. Rec. 4 Pages.
J. Jordan. Exposure Assessment Branch.
Myclobutanil. Aqueous photolysis of RH-3866.
Acc. No. 265746.

May 22, 1987. Review. 5 Pages.
Emil Regelman. Exposure Assessment Branch.
Submission of environmental fate data in support of registra
tion. Page 5 removed-registrant data.
Attachment(s) following:

May 28, 1985. Note. 8 Pages.
Norman Cook. Ecological Effects Branch.
Review and upgrading of study
Data Evaluation Record is attached.
Acute oral LD50 in bobwhite quail.
Acc. No 072894
Pages 6-8 removed-registrant data.

*End of attachments*

June 16, 1987. Memorandum. 28 Pages.
Richard Loranger. Residue Chemistry Branch.
PP #7G3479/FAP #7H5523 - Myclobutanil on Apples and Grapes -
Evaluation of Analytical Method and Residue Data (Accession
Numbers 266026 through 266032). RCB Nos. 1954 through 1956.
Inert ingredient information on page 7 is not included.

July 1, 1987. Memorandum. 6 Pages.
Richard Loranger. Residue Chemistry Branch.
PP #7G3479. Myclobutanil (RH-3866) on Apples and Grapes.
Method Trial Request.

July 1, 1987. Memorandum. 2 Pages.
Richard Loranger. Residue Chemistry Branch.
PP #7G3479. Myclobutanil (RH-3866) on Apples and Grapes.
Request for Analytical Standards.

July 28, 1987. Data Eval. Rec. 18 Pages.
Daniel Reider. Ecological Effects Branch.
One-generation reproductive test, bobwhite quail
Acc. No 265744
Pages 4-18 removed, registrant data.

July 28, 1987. Data Eval. Rec. 19 Pages.
Daniel Reider. Ecological Effects Branch.
One-generation reproductive test, mallard ducks
Acc. No 265744
Pages 4-19 removed, registrant data.

July 31, 1987. Review. 11 Pages.
Daniel Reider. Ecological Effects Branch.
Proposed Registration of Technical and
Two End-use Products for Use on Apples and Grapes
DER attached: Early Life Stage Toxicity Test with Fathead
Minnow
Acc. No 266119.

August 6, 1987. Memorandum. 1 Page.
Edwin Tinsworth. Registration Division.
Expedited Review Request. Myclobutanil - Revised Sections
B and F for PP #7G3479/7H5523.

August 13, 1987. Memorandum. 9 Pages.
Richard Loranger. Residue Chemistry Branch.
PP #7G3479/7H5523. Myclobutanil on Apples and Grapes.
Amendment of 7/28/87. (RCB Nos. 2606, 2607, 2608).

September 1, 1987. Memorandum. 13 Pages.
Charles Frick. Residue Chemistry Branch.
Myclobutanil (Rally) Tolerance Assessment System Tolerance
Assessment. ID Numbers 7G3479 and 7H5523. Action Codes
244 and 264.

September 10, 1987. Memorandum. 17 Pages.
Charles Frick. Residue Chemistry Branch.
Myclobutanil (Rally) Tolerance Assessment System Tolerance
Assessment. ID Numbers 7G3479 and 7H5523. Action Codes
244 and 264.

September 29, 1987. Memorandum. 3 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 707-EUP-RRG
Rally 60 DF Fungicide
Tox review 006650.

October 5, 1987. Memorandum. 5 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 707-EUP-RRG
Rally 60 DF Fungicide
MRID 403432-01, -02.
Tox review 006403.

December 9, 1987. Review. 9 Pages.
Douglas Urban. Ecological Effects Branch.
Proposed EUP on Apples.

December 11, 1987. Memorandum. 2 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil).
The Regulable Residue in Animal Commodities.
RCB No.: N/A. MRID No.: N/A.
Attachment(s) following:

December 9, 1987. Memorandum. 2 Pages.
Allen Jennings. Benefits and Use Division.
Rally, Tolerance Method.

*End of attachments*

December 21, 1987. Review. 8 Pages.
Emil Regelman. Exposure Assessment Branch.
File Nos. 707-ERE, -ERN, -ERR. Rally. Request for
Acceptance of Study Previously Deemed Unacceptable.

December 29, 1987. Memorandum. 2 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Residue
Analytical Methods. RCB No.: N/A. MRID No.: N/A.
Attachment(s) following:

February 13, 1987. Letter. 2 Pages.
Michael Morelli. Rohm and Haas Company.
Rally Fungicide. Pesticide Petition Nos. 7G3479 and 7F3476.
Food Additive Petition Nos. 7H5523 and 7H5524.

*End of attachments*

December 31, 1987. Review. 8 Pages.
Daniel Rieder. Ecological Effects Branch.
Registrant response to previous review
of early life-stage study with fathead
minnow. Pages 4-8 removed, registrant data.

December 31, 1987. Review. 3 Pages.
Daniel Rieder. Ecological Effects Branch.
Registrant response to previous review
of early life-stage study with fathead
minnow.

January 11, 1988. Memorandum. 11 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Request for
Additional Method Trials. RCB No: N/A. MRID No: N/A.

February 3, 1988. Review. 5 Pages.
Emil Regelman. Exposure Assessment Branch.
File No. 707-EUP-RRA.
Myclobutanil aka Systhane and Mancozeb aka Dithane.

February 5, 1988. Memorandum. 137 Pages.
Pamela Hurley. Fungicide-Herbicide Branch.
707-ERE; ERN; ERR/7F3476; 7H5524. RH-3866 (Rally).
Pages 13-23 removed, draft label. Pages 43-50, 84-85, 93-97,
102-106, 127-129 removed, registrant data.
Page 137 removed, inert ingredient information.
Tox review 006580.

February 8, 1988. Memorandum. 145 Pages.
Charles Trichilo. Residue Chemistry Branch.
New Chemical Review of Myclobutanil (RH-3866).
Inert ingredient info on pages 24 and 27 not included.
Pages 95-105 and 139-140 removed, confidential statement
of formula. Pages 122-132 removed, manufacturing process.
Attachment(s) following:

February 8, 1988. Memorandum.
Charles Trichilo. Residue Chemistry Branch.
(cont.)
Pages 129-132 removed, identity of product impurities.
Pages 133-138 and 141-145 removed, quality control
procedures.

*End of attachments*

February 10, 1988. Memorandum. 2 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 707-ERE
Rally 40W Fungicide
MRID 403571-03.
Tox review 006649.

February 10, 1988. Memorandum. 3 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 707-ERN
RH-3866 Technical
MRID 403571-03, -02.
Tox review 006648.

February 23, 1988. Memorandum. 2 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Revised
Analytical Method. RCB No.: None. MRID No. 404980-01.

April 12, 1988. Review. 19 Pages.
Emil Regelman. Exposure Assessment Branch.
File Nos. 707-ERN, -ERR, -ERE, -ROG. RH-0611 WP Fungicide.
Review of Registrant's Response to Previous EAB Reviews.
Pages 5-19 removed, registrant data.

April 12, 1988. Memorandum. 6 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil).
Evaluation of the COB Report on the Petition Method
Validation of Procedure TR 310-84-13, as Amended by Addendum
TR 310-86-09, for Determining Residues of Myclobutanil Per
Se in Beef Liver and Milk. RCB No.: None. MRID No.: N/A.

April 14, 1988. Memorandum. 3 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Defining the
Regulable Residue. RCB No.: None. MRID No.: None.

April 14, 1988. Memorandum. 5 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Evaluation
of the COB Report on the Petition Method Validation of
Procedure TR 310-84-27, as Amended by Addendums TR 31H-86-15
and 31S-87-46, for Determining Residues of Myclobutanil
(RH-3866) and its Alcohol Metabolite, RH-9090, in Apples.

April 15, 1988. Memorandum. 1 Page.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Confirmation
of PMV Request. RCB No.: N/A. MRID No.: N/A.

April 19, 1988. Memorandum. 9 Pages.
Lois Rossi. Fungicide-Herbicide Branch.
707-ERE;ERN;ERR/7F3476;7H5524. RH-3866 (Rally)
Fungicide. Response to Additional Data Submitted on
Dermal Penetration Study
Pages 6-8 removed, registrant data.
Tox review 006727.

April 22, 1988. Review. 14 Pages.
Michael Firestone. Exposure Assessment Branch.
File No. 214, 087. Myclobutanil Exposure Assessment.

April 26, 1988. Memorandum. 22 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Myclobutanil in or on Apples,
Grapes, their Byproducts, Meat, Milk, and Eggs. Follow-up
to the RCB New Chemical Residue Chemistry Review... RCB #s
3431-3435, 3560-3573. MRID #s 404975-00, 01; 405481-00, 01.
Manufacturing process information on page 21 not included.

April 29, 1988. Memorandum. 4 Pages.
Lois Rossi. Fungicide-Herbicide Branch.
707-ERE;ERN;ERR/7F3476;7H5524. RH-3866 (RallyTM)
Fungicide. Response to Comments Submitted by
Registrant on Dominant Lethal Study
Tox review 006684.

May 3, 1988. Review. 3 Pages.
Robert Pilsucki. Ecological Effects Branch.
Submission of raw data in response to
previous EEB review
Acc. No 40480401.

June 1, 1988. Review. 10 Pages.
Frank Davido. Exposure Assessment Branch.
File No. 707-ERL. Systhane, Rally, RH-3866.
Review Dislodgeale Residue Data on Grapes Submitted in
Support of New Chemical Registration.

June 22, 1988. Memorandum. 5 Pages.
Maxie Jo Nelson. Residue Chemistry Branch.
PP #7F3476/FAP #7H5524. Rally (Myclobutanil). Request for
Petition Method Validation of Bound RH-9090 Residues in
Milk. RCB No.: N/A. MRID No.: 406458-01.

August 24, 1988. Review. 8 Pages.
Emil Regelman. Exposure Assessment Branch.
File Nos. 707-ROG, 707-ERN, 707-ERR, 707-ERE. Myclobutanil.
To Submit Additional Information on Aqueous Photolysis of
Myclobutanil, and Adsorption/Desorption of its Triazole
Degradate.

September 12, 1988. Memorandum. 3 Pages.
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3476/FAP #7H5524. Myclobutanil in or on Apples,
Grapes, their Byproducts, Meat, Milk, and Eggs. Amendment of
June 3, 1988. DEB Nos. 3955-3959. MRID Nos. 406458-00, -01.

September 27, 1988. Review. 6 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
File Nos. 707-ERN, -ERR, -ERE, -EER, -ROG, -ERG.
Myclobutanil. Response to EFGWB Comments on Terrestrial
Field Dissipation on Parent and 1,2,4-triazole Metabolite.
Attachment(s) following:

August 15, 1988. Letter. 1 Page.
Michael Morelli. Rohm and Haas Company.
Rally Fungicide. EPA File Symbols 707-EER, -ERE, -ERL,-ERN,
-ERR, -ROG. Reponse to EAB Review of April 12, 1988.

*End of attachments*

September 27, 1988. Review. 3 Pages.
Emil Regelman. Environmental Fate Branch.
response to EFGWB comments on terrestrial field dissipation
on parent and 1,2,4-triazole metabolite.

October 13, 1988. Memorandum. 9 Pages.
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3476/FAP #7H5524. Myclobutanil (Rally) in or on
Apples, Grapes, their Byproducts, Meat, Milk, and Eggs.
Amendments of 8/12/88 and 9/16/88. DEB Nos. 4378-4384,
4412-4413. MRID Nos. 408033-01 thru -04; 408253-01.
HED Project No. 8-1205, 8-1248.

October 25, 1988. Memorandum. 5 Pages.
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3476/FAP #7H5524. Myclobutanil (Rally) in or on
Apples, Grapes, their Byproducts, Meat, Milk, and Eggs.
Amendment of 10/7/88. DEB Nos. 4508-4509. MRID No.: N/A.
HED Project No. 9-0172.

November 3, 1988. Memorandum. 8 Pages.
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3476/FAP #7H5524 and EPA File Symbol 707-ERN, -ERR,
-ERE, -ERL, -EER.
Pending registration information on page 1 is not included.

November 10, 1988. Review. 5 Pages.
Emil Regelman. Environmental Fate Branch.
EUP on stone fruit.

December 7, 1988. Memorandum. 5 Pages.
Catherine Eiden. Environmental Fate & Ground Water Branch.
Leaching Assessment for Myclobutanil (Rally).

February 6, 1989. Review. 4 Pages.
Henry Craven. Ecological Effects Branch.
Experimental Use Permit for stone fruit
EUP issued 3/89.

March 20, 1989. Review. 23 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
File No. 707-EER. Myclobutanil.
Submission of Adsorption/Desorption Study on 1,2,4-triazole.
Pages 7-23 are not included - registrant data.

January 2, 1990. Review. 3 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
petition for permanent tolerance on stone fruits.

January 30, 1990. Review. 3 Pages.
Emil Regelman. Environmental Fate & Ground Water Branch.
petition for permanent tolerance on pome fruits.

February 23, 1990. One-Liner. 6 Pages.
Unknown. Environmental Fate & Ground Water Branch.
Myclobutanil EFGWB One-Liner.

July 25, 1990. Review. 7 Pages.
James Ackerman. Ecological Effects Branch.
Proposed registration of use on Pome
fruits: apples, crabapples, loquats, pears
and quinces.

July 26, 1990. Review. 10 Pages.
James Ackerman. Ecological Effects Branch.
Proposed registration of use on stone
fruits: apricots, cherries, nectarines,
peaches, plums and prunes.

September 26, 1990. Review. 152 Pages.
Hurley. Toxicology Branch.
PEER REVIEW FILES
Systhane (Myclobutanil/Rally)
Pages 62-69, 124-144, 148-152 removed-registrant data. Pend-
ing registration action info on 116, 120, 121 not included.
Tox review 008080.

January 28, 1991. Memorandum. 2 Pages.
Douglas Urban. Ecological Effects Branch.
Review of Myclobutanil (NOVA/RALLY) (DP BARCODE
D160628) amended labeling.

November 19, 1991. DER. 12 Pages.
Daniel Rieder. Ecological Effects Branch.
123-2. Non-Target Plants: Growth and
Reproduction of Aqautic Plants - Tier II. Species Tested:
Selenastrum capricornutum. Pgs 5-9 removed-registrant data.
MRID 41984801.

March 26, 1992. Review. 2 Pages.
Douglas Urban. Ecological Effects Branch.
Response to EEB review of proposed
use on pome fruits and almonds.

May 4, 1992. Review. 15 Pages.
Douglas Urban. Ecological Effects Branch.
Review amendment to remove aerial
application restriction from label
to use myclobutanil on pome fruits
MRID 41984801.

August 20, 1992. Memorandum. 7 Pages.
Douglas Urban. Ecological Effects Branch.
Myclobutanil-- Response to Rebuttals on Turf Review/
Necessity of Further Avian Reproduction Studies.

August 31, 1992. Memorandum. 18 Pages.
Douglas Urban. Ecological Effects Branch.
Proposed Section 18 for use on
strawberries.

September 11, 1992. Review. 4 Pages.
Akiva Abramovitch. Environmental Fate & Groundwater Branch.
Reg./File # 707-225, -221.
Submission of residue accumulation/dissipation data on turf.

September 15, 1992. Memorandum. 3 Pages.
David Jones. Environmental Fate & Ground Water Branch.
Review of "Simulation of Runoff of Myclobutanil and Its
1,2,4-Triazole Metabolite Under Conditions Of Use in
New York Orchards And Vineyards.

November 2, 1992. Review. 2 Pages.
Douglas Urban. Ecological Effects Branch.
Amend Sec. 18 on strawberries to
add San Bernadino County
Sec 18 issued 10/92.

January 25, 1993. Review. 3 Pages.
Akiva Abramovitch. Environmental FAte & Ground Water Branch.
experimental use permit on tomatoes.

January 25, 1993. Review. 4 Pages.
Akiva Abramovitch. Environmental FAte & Ground Water Branch.
emergency exemption on strawberries.

April 5, 1993. Memorandum. 8 Pages.
Anthony Marciorowski. Ecological Effects Branch.
Myclobutanil Avian Reproduction Studies.

May 13, 1993. Review. 7 Pages.
Anthony Marciorowski. Ecological Effects Branch.
Proposed Section 18 for use on tomatoes
Section 18 issued 6/93.

June 16, 1994. Memorandum. 5 Pages.
George Ghali. Health Effects Division.
RfD/Peer Review Report for Myclobutanil (Rally) [Alpha -
butyl-alpha-(4-chlorophenyl)-1H-1,2,4-triazole-1-
propanenitrile].
Tox review 011074.

July 25, 1994. Memorandum. 174 Pages.
Pamela M. Hurley. Toxicology Branch I.
707-210 through 212, 707-215, 707-221, 707-EEE, 707-EGE.
Myclobutanil (Rally, Nova, Eagle). Conditional registration
Follow-up data requirements: Review of Carcinogenicity
studies in rats and mice. Pages 42, 68-75, 124-128, removed,
registration data. MRID No. 428091-01, -02 Tox review 011124.

February 14, 1996. Memorandum. 39 Pages.
Alex Clem. Environmental Fate & Groundwater Branch.
Myclobutanil (RH-3866) formulation Nova 40W/Systhane 2E:
Review of Turf Dissipation Study (MRID 430879-04,
Guideline 164-1)
Pages 10-39 removed, registrant data.

March 30, 2004. Memorandum. 10 Pages.
Sid Abel. Environmental Fate & Effects Division 1.
Section 18 Ecological Risk & Drinking Water Exposure
Assessment for the Control of Soybean Rust using: Boscolid..
...Myclobutanil DP Barcode 296319.

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