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Index of Cleared Science Reviews for Difenoconazole (Pc Code 128847)

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April 17, 1992. Memorandum. 61 Page(s).
K. E. Whitby. Toxicology Branch II.
6(a)(2) 26-Week Oral Feeding Study of CGA 169374 in Dogs 82-1. Project No.: 2-0696.
MRID No. 420900-12. Pages 22-61 not included - registration Data. 42090012-6a2-R029965.
Document (PDF) (588 KB PDF).

August 26, 1992. Memorandum. 437 Page(s).
K. E. Whitby. Toxicology Branch.
Petition for Tolerances of Difenoconazole in Imported Wheat, Barley, and Rye Grain
Raw Agricultural Commodities. MRID 420900-06, -07, -08, -09, -10, -11, -22, -21, -12,
-13,-16,-17,-18,-14,-15,-19,-25,-24,-23,-27,-26,-28,29,30,31. Tox review 009689.
Document (PDF) (9429 KB PDF).
Attachment(s) Following:

August 26, 1992. Memorandum.
K. E. Whitby. Toxicology Branch.
( continued ) Pages 61-93, 106-124, 132-163, 173-174, 176- 179, 183-190,
198-200, 203-204, 207-208, 213-224, 242-254, 270-281, 298, 302-318, 324-326,
329-330, 332-335, 341-361, 367, 369, 373-376, 386-388, 397-400, 408-411,
419-422 and 434-437 removed registration data.

*End of Attachments*

October 22, 1992. Memorandum. 43 Page(s).
Robert Lascola. Chemistry Branch.
PP#E4051. CGA-169374 (Difenoconazole, Dividend) in Imported Wheat, Barley,
and Rye Grain. First Food Use. MRID# 42090001 to -04, -32 to -59, 42303901.
DP Barcode# D172067, D178394.
Document (PDF) (2300 KB PDF).

September 15, 1993. Memorandum. 60 Page(s).
Jess Rowland. Toxicology Branch.
Difenoconazole: Registrant's Response to Deficiencies Cited in Toxicology Review.
MRID 420900-10,-11,-14,-15,-16,-17,-18,-28,-29,-30,-31,-27 and 427100-11, -12.
Pages 30-33, 46-49, 59-60 removed- registrant data. Tox review 010588.
Document (PDF) (2838 KB PDF).

February 24, 1994. Memorandum. 8 Page(s).
George Ghali. Health Effects Division.
RfD / Peer Review Report of Difenoconazole.
Document (PDF) (537 KB PDF).

March 03, 1994. Memorandum. 3 Page(s).
Jess Rowland. Toxicology Branch.
DIFENOCONAZOLE: Response to HED RfD Committee's Recommendations.
(Ref. TXR 009689 & 010588).
Document (PDF) (184 KB PDF).

April 06, 1994. Memorandum. 204 Page(s).
Esther Rinde. Health Effects Division.
Carcinogenicity Peer Review Meeting on Difenoconazole
Pages 46-53, 55-66, 88-100, 102-117, 189-204 removed, registrant data.
Document (PDF) (6375 KB PDF).

May 26, 1994. Memorandum. 3 Page(s).
Health Effects Division..
DRAFT Carcinogenicity Peer review of Difenoconazole excerpt.
Administration of difenoconazole in the diet to CD-1 mice...
Document (PDF) (218 KB PDF).

May 31, 1994. Memorandum. 25 Page(s).
Esther Rinde. Science Analysis & Coordination Branch.
Health Effects Division (HED) Carcinogenicity Peer Review Committee
Draft Document on Difenoconazole (Dividend).
Document (PDF) (1432 KB PDF).

June 16, 1994. Memorandum. 12 Page(s).
G. F. Kramer. Chemistry Branch I.
PP#2F4107. Difenoconazole (Dividend) in/on Wheat, and Animal RACs.
Amendment of 5/18/94. MRID#s 432365-01, -02, & -03. Barcodes D203644 & D203645.
CBTS# 13771 & 13772.
Document (PDF) (935 KB PDF).

July 14, 1994. Memorandum. 1 Page(s).
Reto Engler. Toxicology Branch.
Difenoconazole - Basis for Tolerance Expression.
Document (PDF) (38 KB PDF).

July 22, 1994. Memorandum. 3 Page(s).
G. F. Kramer. Chemistry Branch I.
HED Metabolism Committee Meeting of 7/14/94. PP#2F4107 & PP#2E4051.
Difenoconazole (Dividend).
Document (PDF) (163 KB PDF).

July 22, 1994. Memorandum. 8 Page(s).
Jennifer Wintersteen. Science Analysis Branch.
Difenoconazole: Dietary Exposure Analysis for the Proposed Time-Limited
Use on Wheat (PP# 2F4107) DRES.
Document (PDF) (450 KB PDF).

July 27, 1994. Memorandum. 23 Page(s).
Jess Rowland. Toxicology Branch II.
Carcinogenicity Peer Review of Difenoconazole (Dividend).
Document (PDF) (1424 KB PDF).

December 08, 1998. Memorandum. 3 Page(s).
Lori Brunsman. Science Analysis Branch.
Difenoconazole (Dividend) Quantitative Risk Assessment (Q1*) Based on the Charles
River CD-1 Mouse Chronic Dietary Study With 3/4's Interspecies Scaling Factor.
Document (PDF) (153 KB PDF).

February 09, 1999. Memorandum. 1 Page(s).
Kathleen Depukat. Biological and Economic Analysis Div.
Difenconazole Percent Wheat Treated. Commercial/financial information not included.
Document (PDF) (51 KB PDF).

February 10, 1999. Memorandum. 4 Page(s).
James Hetrick. Environmental Risk Branch.
Tier 1 Drinking Water Assessment for Difenconazole Use as a Wheat
Seed Treatment. DP Barcode 252509. MRIDs 42245128, -31, -35 & -36.
Document (PDF) (186 KB PDF).

March 11, 1999. Memorandum. 12 Page(s).
Susie Chun. Registration Action Branch HED.
Dietary Exposure Analysis for Difenoconazole in/on Wheat and Animal
Commodities (2F4107) and Import Bananas (5E4526)... Toxicological endpoints.
Document (PDF) (787 KB PDF).

March 22, 1999. Memorandum. 60 Page(s).
Dana Vogel. Health Effects Division.
PP#5E04526. Difenoconazole (CGA-169374 Sico 259EC Fungicide) in/on Imported
Bananas and PP#2F4107. Difenoconazole (Dividend) in/on Wheat and Animal RACs.
HED Risk Assessment. Tox review 013294.
Document (PDF) (4141 KB PDF).

March 15, 2000. DER. 13 Page(s).
Andrew Glucksman. Syracuse Research Corp. for ERB.
Study 2. (Interim Report) Rate of degradation... in aerobic soil. MRID 42245131.
Document (PDF) (828 KB PDF).

March 15, 2000. DER. 19 Page(s).
Traci Bludis. Syracuse Research Corp. for ERB.
Study 1. Aqueous photolysis. Pages 10-19 removed, registrant data. MRID 42245128.
Document (PDF) (675 KB PDF).

March 15, 2000. DER. 9 Page(s).
Traci Bludis. Syracuse Research Corp. for ERB.
Study 3. Soil adsorption/desorption. MRID 42245135.
Document (PDF) (599 KB PDF).

April 17, 2000. DER. 27 Page(s).
A. M. Glucksman. Syracuse Research Corp. for ERB.
Study 11. Mobility and dissipation. Pages 9-27 removed, registrant data.
MRID 42245140.
Document (PDF) (617 KB PDF).

April 17, 2000. DER. 36 Page(s).
A. M. Glucksman. Syracuse Research Corp. for ERB.
Study 9. Leaching characteristics. Pages 9-36 removed, registrant data.
MRID 42245137.
Document (PDF) (601 KB PDF).

April 18, 2000. DER. 13 Page(s).
M. K. Mahoney. Syracuse Research Corp. for ERB.
Study 10. Leaching characteristics of aged CGA-169374. Pages 6-13 removed,
registrant data. MRID 42245138.
Document (PDF) (362 KB PDF).

April 18, 2000. DER. 26 Page(s).
A. M. Glucksman. Syracuse Research Corp. for ERB.
Study 8. Aerobic and anaerobic aquatic metabolism. Pages 10-24 removed,
registrant data. MRID 42245134.
Document (PDF) (774 KB PDF).

April 25, 2000. DER. 28 Page(s).
Andrew Glucksman. Syracuse Research Corp. for ERB.
Study 4. Soil photolysis. Pages 13-28 removed, registrant data. MRID 42245129.
Document (PDF) (1040 KB PDF).

April 25, 2000. DER. 43 Page(s).
Andrew Glucksman. Syracuse Research Corp. for ERB.
Study 5. Soil photolysis. Pages 12-43 removed, registrant data. MRID 42245130.
Document (PDF) (897 KB PDF).

April 26, 2000. DER. 20 Page(s).
M. K. Mahoney. Syracuse Research Corp. for ERB.
Study 6. Soil metabolism. Pages 10-20 removed, registrant data. MRID 42245132.
Document (PDF) (708 KB PDF).

April 26, 2000. DER. 33 Page(s).
M. K. Mahoney. Syracuse Research Corp. for ERB.
Study 7. Soil metabolism. Pages 11-33 removed, registrant data. MRID 42245133.
Document (PDF) (784 KB PDF).

September 16, 2005. DER. 45 Pages.
Christopher Salice. Environmental Risk Branch IV.
Data Evaluation Report on the Reproductive Effects of JAU 6476 Technical (Prothioconazole)
on Avian Species Colinus virginianus. PMRA Submission No. 2004-0843. MRID No. 46246042.
PMRA DATA CODE 9.6.3.1. DP Barcode D303488. Guideline 71-4a.
Document (PDF) (1674 KB PDF).

August 05, 2005. Memorandum. 14 Pages.
Jenna Carter. Science Information & Analysis Branch.
Usage Report in Support of Reregistration for the Fungicides: Difenoconazole (128847),
Fenbuconazole (129011), Propiconazole (122101), Prothioconazole (113961),
Tebuconazole(128997), Tetraconazole (120603), Triadimefon (109901).
Document (PDF) (379 KB PDF).

September 26, 2005. Memorandum. 8 Pages.
Jenna Carter. Science Information & Analysis Branch.
Usage Report in Support of Reregistration for the Fungicide Triazoles: Tebuconazole
(128997), Triadimefon (109901), Propiconazole (122101), Triadimenol (127201),
Fenbuconazole (129011), Myclobutanil (128857), Prothioconazole (113961), (128847), (120603).
Document (PDF) (210 KB PDF).

May 10, 2006. Memorandum. 3 Pages.
Kit Farwell. Reregistration Branch 1, HED.
Waiver Request for Triazole Chronic/Oncogenicity Studies. DP# 321328 PC Code 600074.
Related PC codes: 109901, 113961, 120603, 122101, 123909, 125620, 127201, 128847,
128857, 128997, 129011, 600074. MRID Nos. 45575501, 46616401. TXR: 0053729.
Document (PDF) (142 KB PDF).

December 14, 2006. Memorandum. 2 Pages.
Kathleen Raffaele. Toxicology Branch.
Waiver Request for Triazole Acute Neurotoxicity Study. DP# 335069 PC Code 600074.
Related PC codes: 109901, 113961, 120603, 122101, 123909, 125620, 127201, 128847,
128857, 128997, 129011, 600074. MRlD Nos. 45575501, 4647303, 46616401. TXR: 0054490.
Document (PDF) (110 KB PDF).

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