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Index of Cleared Science Reviews for Kathon 287T (Pc Code 128101)
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August 02, 1983. Review. 8 Page(s).
Clayton Bushong. Ecological Effects Branch.
707-RTL Proposed full registartion of manufacturing use of new antifoulant compound.
Inert ingredient information on page 2 is not included.
Document (PDF) (366 KB PDF).
August 11, 1983. Review. 17 Page(s).
Richard Moraski. Exposure Assessment Branch.
Reg./File No.: 707-RTL. Manufacturing use product for marine coatings.
Pages 8-10 not included, draft label. Pages 11-17 not included, registration data.
Acc. No. 249934.
Document (PDF) (340 KB PDF).
September 09, 1983. Memorandum. 13 Page(s).
Carlos A. Rodriguez. Toxicology Branch.
Anti-foulant C-9211-M EPA Reg. No. 707-RTL Acute oral LD-50;
Dermal LD-50 Mutagenic Evaluations. Acc 237355 Tox review 003239.
Document (PDF) (913 KB PDF).
June 08, 1984. Memorandum. 8 Page(s).
Carlos A. Rodriguez. Toxicology Branch.
Anti-foulant C-9211 M. EPA Symbol 707-RTL Review of teratology
study to support the registration of Antifoulant C-9211M products.
Manufacturing process information on pages 2, 4 not included. Tox Review 003876.
Document (PDF) (448 KB PDF).
December 10, 1985. Review. 16 Page(s).
Samuel Creeger. Environmental Assessment Branch.
707-RTL Aqueous Photolysis Protocol. Pages 5-16 removed, registration data.
Document (PDF) (173 KB PDF).
July 30, 1987. Memorandum. 118 Page(s).
Carlos A. Rodriguez. Toxicology Branch.
Antifoulant C-9211M EPA File Symbol 707-RTL Review and evaluate the data
submitted on CHO/HGPRT, Gene Mutation Assay, In Vitro Cytogenetic Assay in
Chinese Hamster Ovary (CHO) Cells, Teratology Study in Rabbits....
Document (PDF) (2684 KB PDF).
Attachment(s) Following:
July 30, 1987. Memorandum.
Carlos Rodriguez. Toxicology Branch.
(continued) Manufacturing process information on pages 4, 5, 11, 23, 24, 53,
54, 86, 87, 88, 95 not included. Pages 13-21,32-51, 64-85, 97-118 removed,
registration data. Tox Review 006342.
*End of Attachments*
December 03, 1987. Review. 61 Page(s).
Therese Dougherty. Exposure Assessment Branch.
707-RTL. Application for full registration for use in antifouling marine coatings.
Inert ingredient information on page 3 not included. Pages 45, 51 removed, registration data.
Acc. No. 265902-265904, 265906, 265911-265913, 265908.
Document (PDF) (2637 KB PDF).
November 21, 1988. Review. 33 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Review of data submissions (707-RTL) Page 7, 12-17 removed, registration data.
MRID 407413-01, 02,03, 04.
Document (PDF) (1454 KB PDF).
February 06, 1989. Memorandum. 1 Page(s).
S. C. Termes. Environmental Fate & Ground Water Branch.
Telephone Conversation with Ms. Wendy Bingeman, Rohm and Haas Company,
concerning metabolite identification in bluegill fish.
Document (PDF) (59 KB PDF).
August 28, 1989. Review. 12 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Review of confirmation of radiopurity. Review of supplemental report to fish
accumulation studies. Review of protocols (photolysis in water/sea; Aerobic/
Anaerobic aquatic metabolism; Adsorption/desorption; Column leaching.
Pages 11-12 removed, RD.
Document (PDF) (603 KB PDF).
January 02, 1990. Review. 23 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Review of protocol for aquatic field dissipation studies.
Pages 7-23 removed, registration data.
Document (PDF) (357 KB PDF).
May 03, 1990. Review. 5 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Determine if previously submitted data support these uses and, if not, indicate
additional data requirements. Inert ingredient information on page 5 not included.
707-EET, 707-EEU, 707-EEL.
Document (PDF) (233 KB PDF).
May 15, 1990. Memorandum. 24 Page(s).
Linda Taylor. Toxicology Branch.
Kathon 287T- Technical Grade of Active Ingredient.
Inert ingredient information on pages 1, 2 not included.
Tox Review 007925.
Document (PDF) (1676 KB PDF).
May 15, 1990. Review. 4 Page(s).
James Akerman. Ecological Effects Branch.
Which studies are needed to evaluate Kathon and its formulated
products for use as mildewcides.
Document (PDF) (291 KB PDF).
July 05, 1990. Review. 5 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
707-RTL Review cover letter and comment Submission 625912. [related to fish
bioaccumulation data previously reviewed] Inert ingredient information on
page 4 is not included. Page 5 removed, registrant data.
Document (PDF) (221 KB PDF).
February 28, 1992. Review. 65 Page(s).
Douglas Urban. Ecological Effects Branch.
Studies Submitted for Review: Sheepshead Minnow Early Lifestage Study 417415-04
MRIDs 417415-02, 417415-03, 417568-01, 417415-01, 417415-05, 417568-02, 417415-06.
Document (PDF) (2973 KB PDF).
July 29, 1992. Memorandum. 24 Page(s).
Linda Taylor. Toxicology Branch.
Kathon 287T Industrial Mildewcide (707-EEU) Submission of 28-Day Oral/2-Week
Recovery Study in Support of the Registration. MRID 422149-03. Manufacturing
process information on pages 4, 5 not included. Tox review 009636.
Document (PDF) (1265 KB PDF).
October 01, 1992. Memorandum. 20 Page(s).
Doug Urban. Ecological Effects Branch.
Kathon 886 Biocide Data Review. Avian Dietary LC50 Test using Bobwhite Quail.
Avian Dietary LC50 Test using Mallard Duck.
Pages 8-10, 17-19 removed, registration data. MRID 422149-01, -02.
Document (PDF) (723 KB PDF).
February 05, 1993. DER. 17 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 6. Metabolism of RH-5287 in bluegill sunfish. 165-4 MRID 41845006.
Pages 4-17 removed, registration data.
Document (PDF) (218 KB PDF).
February 05, 1993. DER. 18 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 5. Leaching. 163-1 MRID 41845005. Pages 6-18 removed, registration data.
Document (PDF) (333 KB PDF).
February 05, 1993. DER. 24 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 4. Soil adsorption/desorption. 163-1 MRID 41845004.
Pages 4-24 removed, registration data.
Document (PDF) (220 KB PDF).
February 05, 1993. DER. 29 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 1. Aqueous photolysis. 161-2 MRID 41845001
Pages 6-29 removed, registration data.
Document (PDF) (366 KB PDF).
February 05, 1993. DER. 37 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 3. Aerobic aquatic metabolism. 162-4 MRID 41845003.
Pages 7-37 removed, registration data.
Document (PDF) (401 KB PDF).
February 05, 1993. DER. 42 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
Study 2. Anaerobic aquatic metabolism. 162-3 MRID 41845002.
Pages 6-42 removed, registration data.
Document (PDF) (382 KB PDF).
February 11, 1993. Review. 15 Page(s).
Akiva Abramovitch. Environmental Fate & Ground Water Branch.
Review of studies submitted for registration of the manufacturing product C-9211M
(RH-5287 active ingredient), marine antifoulant. MRID's 41845001 thru 41845006,
42341101 and 02. Pages 12-15 removed, registration data.
Document (PDF) (688 KB PDF).
February 24, 1993. Review. 3 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
000707-RTL Review rebuttals to EEB study reviews of data submitted previously.
MRID 417415-01, -04, -05.
Document (PDF) (131 KB PDF).
October 07, 1993. Memorandum. 7 Page(s).
Irving Mauer. Toxicology Branch.
Kathon.... Tox Data submitted under MRID 42619501 ID Nos. 00707-EEG, EET
& RTL Acute inhalation study in Rats. Tox review 010621.
Document (PDF) (211 KB PDF).
March 30, 1994. Memorandum. 6 Page(s).
Linda Taylor. Toxicology Branch.
Kathon 287T Industrial Microbicide (707-EEU) Response to Agency Letters dated
5/1/91 and 12/2/92 Re: Data Requirements. MRID 429777-01. Tox review 010852.
Document (PDF) (395 KB PDF).
February 17, 1995. Memorandum. 6 Page(s).
Siroos Mostaghimi. Environmental Fate & Ground Water Branch.
A study by Rohm & Haas conducted to evaluate the environmental dissipation of the
compound RH-5287 (active ingredient of the marine antifoulant formulation C-9211)
....DP Barcode: D163686. Pages 3-6 removed, Registration Data.
Document (PDF) (171 KB PDF).
June 16, 1995. Memorandum. 87 Page(s).
Linda Taylor. Toxicology Branch.
Kathon 287T Industrial Microbicide (707-EEU) Study Reviews and Data
Requirements. Pages 16-17, 58-59 removed, registration data.
MRID 434716-01 thru 434716-10. Tox review 011587.
Document (PDF) (1179 KB PDF).
October 13, 1995. Memorandum. 2 Page(s).
Yung Yang. Toxicology Branch.
Inhalation study on formulated Kathon products. MRID 438475-01.
Document (PDF) (81 KB PDF).
September 13, 1996. Memorandum. 4 Page(s).
Silvia Termes. Environmental Fate & Ground Water Branch.
4,5 - Dichloro.... New Uses ID 707-EEU, Kathon 287T. DP Barcode D212647.
Document (PDF) (170 KB PDF).
September 23, 1996. Review. 3 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Proposed registration of industrial aquatic outdoor use patterns for Kathon 287T.
Request by RD to Determine if Adequate Database Exists to Support Uses.
DP Barcode: D212646.
Document (PDF) (159 KB PDF).
December 08, 1999. Memorandum. 13 Page(s).
Timothy McMahon. Risk Assessment & Science Support Branch.
4,5-Dichloro-2-n-octyl-3(2H)-isothiazolone [C9211; RH-287] Report of the Hazard
Identification Assessment Review Committee. Tox review 013888.
Document (PDF) (795 KB PDF).
October 19, 2000. Memorandum. 35 Page(s).
Srinivas Gowda. Regulatory Management Branch AD.
Review of data on the chronic toxicity of RH-287 to Mysid (Americamysis bahia).
MRID 45153101..
Document (PDF) (603 KB PDF).
September 25, 2007. DER. 14 Pages.
Steven Malish. Risk Assessment & Science Support Branch.
Metabolism - Rat; OPPTS 870.7485; OECD 417. DP Barcode: 341456.
MRID 47154008.
Document (PDF) (289 KB PDF).
October 17, 2007. DER. 16 Pages.
S. L. Malish. Risk Assessment & Science Support Branch.
Toxicology Study Reviews of Kathon ™ (Kathon 886 composed of Kathon 651
and Kathon 573) and their Kathon Metabolite; Othilinone (Kathon RH-893)
and a Metabolite of Kathon 287. EPA Reg. No.: 707-GNT-Kathon 287 WT...
DP Barcode: D341456. MRID 47154016.
Document (PDF) (351 KB PDF).