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Index of Cleared Science Reviews for Thidiazuron (Pc Code 120301)

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August 09, 1976. Review. 9 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
Reg. No. 2139-EUP-22 EUP on cotton.
Document (PDF) (522 KB PDF).

June 05, 1978. Review. 4 Page(s).
Ronald Ney. Efficacy & Ecological Effects Branch.
Reg. No. 2139-EUP-23. Dropp Cotton Defoliant. Use on Cotton.
Document (PDF) (164 KB PDF).

October 31, 1978. Review. 3 Page(s).
Charles Bowen. Ecological Effects Branch.
SN 49537 or Dropp Technical. 96-Hour Static Bioassay on Warm
and Cold Water Fishes.
Document (PDF) (112 KB PDF).

November 14, 1978. Review. 9 Page(s).
Gunter Zweig. Environmantal Fate Branch.
Reg. No.: 2139-EUP-23, 6G1807. Use on cotton.
Document (PDF) (378 KB PDF).

January 30, 1980. Review. 2 Page(s).
R. W. Cook. Environmental Fate Branch.
Reg. No. 2139-EUP-23. Dropp Cotton Defoliant. Extension and Expansion of EUP.
Document (PDF) (76 KB PDF).

February 12, 1980. Article. 14 Page(s).
Charles Knowles, et. Al. University of Missouri.
Thidiazuron Uptake, Distribution and Metabolism in Bluegills and Channel Catfish.
Journal of Environmental Science and Health, B15(4), Pages 351-364 (1980).
Document (PDF) (6207 KB PDF).

September 13, 1980. Review. 6 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 2139-EUP-23. Dropp 50 WP. New Rotational Crop Data to Support
Removal of the Restriction.
Document (PDF) (285 KB PDF).

December 15, 1980. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 2139-EUP-23. Dropp. Cotton Defoliant.
Document (PDF) (88 KB PDF).

October 09, 1981. Review. 48 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 2139-REE. Dropp. Use as Defoliant on Cotton.
Document (PDF) (1731 KB PDF).

October 29, 1981. Memorandum. 7 Page(s).
William Dykstra. Toxicology Branch.
Thidiazuron (SN 49538); Review of Validated Final Report of IBT No. 8533-09630;
Three-Generation Reproduction Study in Albino Rats. Caswell #659A.
Document (PDF) (352 KB PDF).

November 25, 1981. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 2139-REE. Dropp. Response to Questions Raised in Previous Submission.
Document (PDF) (92 KB PDF).

February 18, 1982. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 2139-REE. Dropp. Rotational Crop Data to Support
Change in Rotational Crop Restriction.
Document (PDF) (84 KB PDF).

March 26, 1982. Review. 2 Page(s).
Laurence Chitlik. Toxicology Branch.
Two Year Chronic Oral Toxicity Study with SN 49 537 in Albino Rats.
Tox Review 002569.
Document (PDF) (104 KB PDF).

April 05, 1982. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 2139-EUP-23. Dropp. Review Merit of ULV Treatment
with Dropp in an Oil Carrier.
Document (PDF) (131 KB PDF).

April 30, 1982. Memorandum. 21 Page(s).
Gary Burin. Toxicology Branch.
PP #1F2527, 1H5308 and 2139-REE; Request for Tolerances of Thidiazuron on Cotton
(0.4 ppm); Milk (0.05 ppm); Eggs (0.1 ppm); Meat, Fat and Byproducts of Cattle,...
Acc. Nos. 070127,099842, 070128, 070129, Tox. Chem. No. 659A
Tox review 001839, 002308.
Document (PDF) (1316 KB PDF).
Attachment(s) Following:

April 23, 1982. Letter. 2 Page(s).
Margareta Lambert. Nor-Am Agricultural Products, Inc.
Re: Examination of Skulls in Rabbit Teratology Study.

*End of Attachments*

May 02, 1982. Review. 2 Page(s).
Laurence Chitlik. Toxicology Branch.
24-Month Chronic Oral Carcinogenicity Study with SN 49 537 in Swiss White Mice.
Tox Review 002567.
Document (PDF) (110 KB PDF).

May 05, 1982. Memorandum. 4 Page(s).
Gary Burin. Toxicology Branch.
Review of Validated Thidiazuron Mouse Oncogenicity Study Conducted at IBT
(No. 8580-10725). Tox Chem 659A. Tox review 002303.
Document (PDF) (225 KB PDF).

May 06, 1982. Memorandum. 4 Page(s).
Gary Burin. Toxicology Branch.
Review of Validated Thidiazuron Chronic Rat Sutdy Conducted at IBT
(No. 8560-09631). Caswell #659A. Tox review 002304.
Document (PDF) (221 KB PDF).

May 11, 1982. Memorandum. 2 Page(s).
Gary Burin. Toxicology Branch.
PP #1F2527, 1H5308 and 2139-REE; Addendum to Review of April 30, 1982
(Request for Tolerances of Thidiazuron on Cotton, Milk, Eggs, Meat; Fat and
Byproducts of Cattle, Goats, Hogs, Horses, Poultry and Sheep; and Cottonseed Hulls).
Caswell #659A.
Document (PDF) (89 KB PDF).

May 24, 1982. Memorandum. 1 Page(s).
R. S. Quick. Residue Chemistry Branch.
PP #1F2527/FAP #1H5308. Thidiazuron. Results of the Method Tryout.
Document (PDF) (54 KB PDF).

August 02, 1982. Memorandum. 3 Page(s).
Gary Burin. Toxicology Branch.
Review of Thidiazuron Mutagenicity Studies; Reg. #2139-122.
Document (PDF) (156 KB PDF).

September 29, 1982. Memorandum. 1 Page(s).
Gary Burin. Toxicology Branch.
Additional Comments on Thidiazuron Rat Teratology Studies. Acc. No. 070129.
Document (PDF) (55 KB PDF).

October 21, 1982. Memorandum. 1 Page(s).
Gary Burin. Toxicology Branch.
Review of Protocol for Rat Chronic/Oncogenicity Study of Thidiazuron.
Document (PDF) (49 KB PDF).

November 24, 1982. Memorandum. 1 Page(s).
Gary Burin. Toxicology Branch.
Review of Revised Protocol for 2-Year Rat Chronic and Oncogenicity Study
of Thidiazuron. Caswell #659A.
Document (PDF) (50 KB PDF).

December 15, 1982. Memorandum. 1 Page(s).
Gary Burin. Toxicology Branch.
Review of Protocol for One-Year Chronic Dog Study of Thidiazuron.
Tox. Chem. 659A. Reg. No. 2139-122.
Document (PDF) (49 KB PDF).

December 31, 1982. Report. 11 Page(s).
John Strange. Dynamac Corporation.
IBT Validation Report - Thidiazuron. 90-Day Subacute Oral toxicity Study
with SN 49537 Technical in Beagle Dogs (IBT No. 8531-08338).
Document (PDF) (574 KB PDF).

December 31, 1982. Report. 7 Page(s).
John Strange. Dynamac Corporation.
IBT Validation Report - Thidiazuron. 90-Day Subacute Oral Toxicity Study
with SN 49537 in Albino Rats (IBT No. 8560-08337).
Document (PDF) (342 KB PDF).

January 07, 1983. Memorandum. 2 Page(s).
Gary Burin. Toxicology Branch.
Evaluation of Validated IBT Study No. 8531-08338: Ninety-Day Oral Feeding
Study of SN 49537 (Thidiazuron) in Beagle Dogs. Tox. Chem. No. 659A.
Document (PDF) (103 KB PDF).

January 07, 1983. Memorandum. 2 Page(s).
Gary Burin. Toxicology Branch.
Evaluation of Validated IBT Study No. 8560-08337: Ninety-Day Oral Feeding
Study of SN 49537 (Thidiazuron) in Rats. Tox. Chem. No. 659A.
Document (PDF) (109 KB PDF).

January 31, 1983. Memorandum. 2 Page(s).
Gary Burin. Toxicology Branch.
Review of Comments on Thidiazuron Mouse Dominant Lethal Study;
Reg. No. 2139-122; Acc. No. 248401; Caswell #659A.
Document (PDF) (96 KB PDF).

March 16, 1983. Memorandum. 2 Page(s).
Gary Burin. Toxicology Branch.
Expansion of Statistical Comparison Presented in Memo of 8/2/82:
Review of Dominant Lethal Test of Thidiazuron. Caswell #659A.
Document (PDF) (75 KB PDF).

April 21, 1983. Memorandum. 2 Page(s).
John Chen. Toxicology Branch.
Thidiazuron (Dropp) 2139-122: Review of Protocol for the Human Lymphocytes
Cytogenetics (Litton Bionetics Protocol No. 449.1). Caswell #659A.
Document (PDF) (100 KB PDF).

July 13, 1983. Memorandum. 1 Page(s).
John Chen. Toxicology Branch.
Thidiazuron (Dropp) 2139-122: Review and Evaluation of the Revised Protocol for
the Chromosome Aberrations in Human Lymphocytes with and without in-vitro Metabolic
Activation (Litton Bionetics Protocol No. 449.1 - Edition 6). Caswell #659A.
Document (PDF) (58 KB PDF).

December 05, 1986. Review. 23 Page(s).
Herbert Manning. Exposura Assessment Branch.
Thidiazuron. Ground Water Data Call-In.
Document (PDF) (1144 KB PDF).

July 17, 1987. Memorandum. 5 Page(s).
Linda Propst. Residue Chemistry Branch.
45639-EUP-36. EUP Request to use Thidiazuron and Diuron on cotton as a defoliant.
MRID Nos. 401783-02, 401783-03, 401783-04, 401703-05, and 402033-03. RCB No. 2396.
Page 5 removed-manufacturing process and confidential statement of formula.
Document (PDF) (313 KB PDF).

September 28, 1987. Memorandum. 92 Page(s).
Stephen Dapson. Toxicology Branch.
Review of a 1-Year Dog Study, an in-vitro Cytogenetic Assay in Human Lymphocytes
and a 104-Week Chronic Toxicity/ Oncogenicity in Rats...Tox Review 006330.
Manufacturing process info on page 7 is removed.
Pages 26-34, 46-55, 77-92 removed, registrant data.
Document (PDF) (2371 KB PDF).

April 05, 1988. Review. 6 Page(s).
Patrick Holden. Exposure Assessment Branch.
Thidiazuron. Ground Water Data Call-In Response.
Document (PDF) (432 KB PDF).
Attachment(s) Following:

November 04, 1987. Letter. 3 Page(s).
Cindy Keller. Nor-Am Chemical Company.
Data Call-In Notice for Ground Water Data - Thidiazuron.
James Ackerman's September 1, 1987 Letter to Nor-Am.

*End of Attachments*

February 22, 1989. Review. 2 Page(s).
Henry Jacoby. Environmental Fate & Ground Water Branch.
Dropp. Request extension for Aqueous Photolysis Study.
Document (PDF) (58 KB PDF).

August 10, 1989. One-Liner. 4 Page(s).
J. Hannan. Environmental Fate & Ground Water Branch.
Thidiazuron.
Document (PDF) (115 KB PDF).

December 06, 1989. Review. 19 Page(s).
Paul Mastradone. Environmental Fate & Ground Water Branch.
Review of data submitted in response to registration standard and response to initial
registration standards. MRID 411882-01. Pages 11-19 removed, registrant data.
Document (PDF) (564 KB PDF).

December 06, 1989. Review. 5 Page(s).
James A. Hetrick. Environmental Fate & Ground Water Branch.
Data Evaluation Review; Aqueous photolysis MRID No. 411882-1.
Document (PDF) (293 KB PDF).

May 31, 1990. Review. 19 Page(s).
Stephen Dapson. Toxicology Branch.
Review additional data submitted in support of a chronic toxicity study in dogs,
a chronic in rats, and an in vitro cytogenetic assay in human lymphocytes with
thidiazuron. MRIDs 40798300 thru 40798304, 40908501, 41191701. Tox review 007950.
Document (PDF) (859 KB PDF).

August 13, 1992. Memorandum. 13 Page(s).
Walter Kozumbo. Toxicology Branch II.
(Thidiazuron Technical): Review of 2 studies submitted by the registrant on the primary
dermal irritation (81-5) and the primary eye irritation (81-4) of Thidiazuron Technical
in rabbits. MRID 420996-01, 02. Pages 6-8, 12-13 removed-RD. Tox review 009670.
Document (PDF) (431 KB PDF).

December 22, 1992. Review. 7 Page(s).
Deborah McCall. Health Effects Division.
PHASE FOUR REVIEW H. E. D. Thidiazuron (Dropp 50WP).
Document (PDF) (432 KB PDF).

January 12, 1993. Memorandum. 152 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Phase IV Response for Reregistration D184069, D166717, D172925, and D170796.
Thidiazuron. MRID 421320-02. Pages 16-18, 45-46, 53-55, 61-63, 70-71, 79-81,
94-99, 121-128, 134, 142-144, 150-151 removed-registrant data.
Document (PDF) (5698 KB PDF).

January 12, 1993. Review. 3 Page(s).
Judy Smith. Occupational & Residential Exposure Br.
OREB Transmittal Sheet for Phase 4 Reviews
Data Submitter(s): 045639 Nor-Am Chemical Company.
Document (PDF) (191 KB PDF).

February 02, 1993. Review. 12 Page(s).
Felecia Fort. Chemistry Branch.
CBRS Transmittal Sheet for Phase 4 Reviews
Data Submitter(s): NOR-AM Chemical Company.
Document (PDF) (910 KB PDF).

April 28, 1993. Memorandum. 11 Page(s).
Arnet Jones. Environmental Fate & Ground Water Branch.
Thidiazuron - List D Phase 4 Review.
Document (PDF) (656 KB PDF).

April 30, 1993. Review. 195 Page(s).
Paul J. Mastradone. Environmental Fate & Ground Water Branch.
Phase IV review of environmental fate data.
MRID 42069203, 41188201, 41364910, 41364902, 00156241, 41950101, 41945201,
41364909, 41761105, 00030793, 41364907, 41364908.
Pages 27-30, 46-50, 56-72, 75-92, 98-118, 124-149, 158-176, 189-195 removed, RD.
Document (PDF) (4552 KB PDF).

June 10, 1993. Memorandum. 38 Page(s).
Stephen Dapson. Toxicology Branch II.
Thidiazuron: Review of a general metabolism study in rats and two mutagenicity studies.
MRID 417611-02, -03, 425290-01. Pages 8-24, 35-38 removed, registrant data.
Page 30 removed, detailed methodology. Tox review 010318.
Document (PDF) (1094 KB PDF).

July 12, 1993. Memorandum. 14 Page(s).
Evert Byington. Science Analysis Branch.
Transmittal of EFED List D Review for Thidiazuron (120301).
Document (PDF) (728 KB PDF).

July 20, 1993. Review. 5 Page(s).
Stephen Funk. Chemistry Branch II.
Thidiazuron (Dropp 50WP; List D, Case 4092, PC 120301): 6(a) (2) Data from
Rotational Crop Study. DP Barcode No. D188667. CBRS No. 11481. MRID No. 42660901.
Document (PDF) (257 KB PDF).

August 06, 1993. Memorandum. 5 Page(s).
Felicia Fort. Chemistry Branch II.
Thidiazuron. Additional Study Into the Nature of the Residue in Animals.
MRID Nos. 427787001 and 42778002. Case No. 4092. CBRS No. 12009.
DP Barcode D192068.
Document (PDF) (353 KB PDF).

October 07, 1993. Memorandum. 5 Page(s).
R. W. Cook. Chemistry Branch Tolerance Section.
Thidiazuron and Diuron on Cottonseed. EPA Reg. No. 45639-RAR.
DP Barcode D189453. CBTS No. 11638. MRID 42668311, 42668312.
Document (PDF) (313 KB PDF).

November 02, 1993. Memorandum. 3 Page(s).
Stephen Funk. Chemistry Branch II.
Thidiazuron (Dropp 50WP; List D, Case 4092, Chemical 120301): Additional
Rotational Crop Data for Lettuce and Label Amendment. DP Barcode No. D195583.
CBRS No. 12640. MRID No. none.
Document (PDF) (172 KB PDF).

March 04, 1994. Memorandum. 3 Page(s).
Felicia Fort. Chemistry Branch II.
Thidiazuron. Storage Stability in Cottonseed. List D Chemical No. 120301.
Case No. 4092. MRID No. 42847601. CBRS No. 12921. DPBarcode D195636.
Document (PDF) (192 KB PDF).

April 08, 1994. Memorandum. 6 Page(s).
Steven Knizner. Chemistry Branch II.
Thidiazuron. Protocol for Confined Rotational Crop Study. Reregistration.
Case No. 4092. Chemical No. 120301. No MRID #. DPBarcode D201247. CBRS #13,481.
Document (PDF) (354 KB PDF).

May 17, 1994. Memorandum. 3 Page(s).
Joel Garbus. Chemistry Branch Tolerance Support.
45639-EUP-049: Diuron/Thidiazuron (GINSTAR EC). Amended Label to Reduce
Plant-Back Intervals for Rotational Crops. DP Barcode D197251 CBTS No. 12901.
Document (PDF) (160 KB PDF).

July 19, 1994. Memorandum. 2 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
The Ecological Effect Branch's (EEB) review of registrant's request for reevaluation
and possible upgrade of guideline 72-4(b), Daphnia magna study with Thidiazuron,
(old MRID 421320-02; new MRID 430752-01). DP Barcode 201400 - (Chemical Code 120301).
Document (PDF) (96 KB PDF).

July 22, 1994. Review. 6 Page(s).
Silvia C. Termes. Environmental Fate & Ground Water Branch.
Waiver Request for Aerobic Soil Metabolism (162-1) with Thiadiazol-labelled
Thidiazuron. DP Barcode D202913; PC No. 120301. Reregistration Case No. 4092.
Document (PDF) (360 KB PDF).

September 07, 1995. Memorandum. 5 Page(s).
Felicia Fort. Chemistry Branch II.
Thidiazuron Metabolism. Issues to be Presented to the Metabolism Committee
on September 18, 1995.
Document (PDF) (220 KB PDF).

December 04, 2003. DER. 29 Pages.
William Evans. Environmental Risk Branch I.
SEEDLING EMERGENCE EC25 TEST 122-1 (TIER I) an d 123-1 (TIER II).
Thidiazuron SC42-Determination of Effects on Seedling Emergence and Seedling
Growth of Ten Plant Species. MRID No.: 45908501. DP Barcode: D289980.
Document (PDF) (1348 KB PDF).

December 04, 2003. DER. 32 Pages.
William Evans. Environmental Risk Branch I.
VEGETATIVE VIGOR EC25 TEST 122-1 (TIER I) and 123-1 (TIER II).
Thidiazuron SC42-Determination of Effects on Vegetative Vigor of Ten Plant Species.
MRID No.: 45921501. DP Barcode: D291684.
Document (PDF) (9047 KB PDF).

May 17, 2004. DER. 16 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of Thidiazuron on the Marine Diatom,
Skeletonema costatum. MRID No. 46203505. DP Barcode: D294536.
Document (PDF) (3719 KB PDF).

May 26, 2004. DER. 11 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the Acute Toxicity of Thidiazuron Technical to Freshwater
Invertebrates - Daphnia magna. MRID No. 46203503. DP Barcode: D294536.
Document (PDF) (3118 KB PDF).

November 08, 2004. Memorandum. 39 Pages.
Toiya Jimerson. Reregistration Branch 1.
Thidiazuron Residue Chemistry Studies (4). MRID No.: 46298401, 46298402,
46298403, 46298404. DP Barcode No.: D294543. Reregistration Case No.: 4092.
Document (PDF) (1200 KB PDF).

November 16, 2004. DER. 10 Pages.
William Evans. Environmental Risk Branch.
Data Evaluation Report on the Acute Dietary Toxicity of Technical Thidiazuron to
Northern Bobwhite Quail (Colinus virginianus). MRID No. 46203502. DP Barcode: D294536.
Document (PDF) (2141 KB PDF).

November 16, 2004. DER. 10 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of AE C421200 (Metabolite of Thidiazuron)
to Rainbow Trout (Oncorhynchus mykiss). MRID No. 46203511. DP Barcode: D294536.
Document (PDF) (2091 KB PDF).

November 16, 2004. DER. 10 pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of AE F132345 (Metabolite of Thidiazuron)
to Rainbow Trout (Oncorhynchus mykiss). MRID No. 46203515. DP Barcode: D294536.
Document (PDF) (2104 KB PDF).

November 16, 2004. DER. 12 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of Thidiazuron Technical to aquatic
vascular plants Lemna gibba. MRID No. 46203506. DP Barcode: D294536.
Document (PDF) (2769 KB PDF).

November 16, 2004. DER. 13 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of AE F132347 (Metabolite of Thidiazuron)
to Rainbow Trout (Oncorhynchus mykiss). MRlD No. 46203508. DP Barcode: D294536.
Document (PDF) (2730 KB PDF).

November 16, 2004. DER. 16 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of AE C421200 (Thidiazuron Metabolite)
on the Algae, Scenedesmus subspicatus. MRID #: 46203513. DP Barcode: D294536.
Document (PDF) (5691 KB PDF).

November 16, 2004. DER. 18 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of Thidiazuron on the Algae, Anabaena
flos-aquae. MRlD No. 46203504. DP Barcode: D294536.
Document (PDF) (5565 KB PDF).

November 16, 2004. DER. 18 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluatioo Report on tbe acute toxicity of AE F132345 (Thidiazuron Metabolite)
on the Algae, Scenedesmus subspicatus. MRID No. 46203517. DP Barcode: D294536.
Document (PDF) (4307 KB PDF).

November 16, 2004. DER. 6 Pages.
William Evans. Environmental Risk Branch I.
HONEY BEE - ACUTE CONTACT LC50 TEST 141-1. Contact toxicity (LD50) to
the honey bees (Apis mellifera L.), Thidiazuron, Water miscible suspension
concentrate 500 g/L. DP Barcode: D294536. MRID No.: 46203518.
Document (PDF) (1444 KB PDF).

November 16, 2004. DER. 6 Pages.
William Evans. Environmental Risk Branch I.
HONEY BEE - ACUTE ORAL LC50 TEST Non-guideline. Oral toxicity (LD50) to
the honey bees (Apis mellifera L.), Thidiazuron, Water miscible suspension
concentrate 500 g/L. DP Barcode: D294536. MRID No.: 46203519.
Document (PDF) (1432 KB PDF).

November 16, 2004. DER. 6 Pages.
William Evans. Environmental Risk Branch I.
Predatory Mite - Acute Contact and Reproduction Tests No OPP Guideline
Applicable. Toxicity to the predatory mite Typhlodromus pyri Scheuten
(Acari. Phytoseiidae) in the laboratory, Thidiazuron,...DP Barcode: D294536.
MRID No.: 46203521.
Document (PDF) (1545 KB PDF).

November 16, 2004. DER. 8 Pages.
William Evans. Environmental Risk Branch I.
EARTHWORM SUBCHRONIC TOXICITY TEST OPPTS 850.6200. Thidiazuron, SC 500 G/L:
A 14-Day Acute Toxicity Test with the Earthworm Eisenia fetida.
MRID No.: 46203522. DP Barcode: D294536.
Document (PDF) (2614 KB PDF).

November 16, 2004. DER. 9 Pages.
William Evans. Environmental Risk Branch I.
EARTHWORM SUBCHRONIC TOXICITY TEST OPPTS 850.6200. AE F132345:
An Acute Toxicity Study with the Earthworm (Eisenia Fetida) in an Artificial
Soil Substrate. MRID No.: 46203514. DP Barcode: D294536.
Document (PDF) (2188 KB PDF).

November 16, 2004. DER. 9 Pages.
William Evans. Environmental Risk Branch I.
EARTHWORM SUBCHRONIC TOXICITY TEST OPPTS 850.6200. AE F132347:
An Acute Toxicity Study with the Earthworm (Eisenia fetida) in an Artificial
Soil Substrate. MRID No.: 46203507. DP Barcode: D294536.
Document (PDF) (2210 KB PDF).

November 16, 2004. DER. 9 Pages.
William Evans. Environmental Risk Branch I.
Parasitic Wasp - Acute Contact and Reproduction Tests No OPP Guideline Applicable.
Toxicity to the parasitoid wasp Aphidius rhopalosiphi (DeStephani-Perez)
(Hymenoptera: Braconidae) in the laboratory, Thidiazuron,...DP Barcode: D294536.
MRID No.: 46203520.
Document (PDF) (1982 KB PDF).

November 17, 2004. DER. 10 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the Acute Toxicity of AE F132347 (Metabolite of Thidiazuron)
to Freshwater Invertebrates- Daphnia magna. MRID No. 46203509. DP Barcode: D294536.
Document (PDF) (2166 KB PDF).

November 17, 2004. DER. 10 pages.
William Evans. Environmental Risk Branch I.
HONEY BEE - ACUTE CONTACT & ORAL LC50 TEST 141-1 and Non-
guideline. Assessment of Side Effects of AE B 049537 00 1D99 0003 (Thiadiazuron, Techn,)
to the Honey Bee, Apis mellifera L. in the Laboratory. DP Barcode: D294536.
MRID No.: 46203501.
Document (PDF) (2765 KB PDF).

November 17, 2004. DER. 12 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the Acute Toxicity of AE F132345 (Metabolite of Thidiazuron)
to Freshwater Invertebrates - Daphnia magna. MRlD No. 46203516. DP Barcode: D294536.
Document (PDF) (2836 KB PDF).

November 17, 2004. DER. 17 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the acute toxicity of AE F132347 (Thidiazuron Metabolite)
on the Algae. Scenedesmus subspicatus. MRID #: 46203510. DP Barcode: D294536.
Document (PDF) (4135 KB PDF).

November 18, 2004. DER. 10 Pages.
William Evans. Environmental Risk Branch I.
Data Evaluation Report on the Acute Toxicity of AE C421200 (Metabolite of
Thidiazuron) to Freshwater Invertebrates - Daphnia magna. MRID No. 46203512.
DP Barcode: D294536.
Document (PDF) (2025 KB PDF).

December 06, 2004. Review. 22 Pages.
Felecia Fort. Reregistration Branch 1.
DACO 7.4.1/OPPTS 860.1500/OECD lIA 6.3.1, 6.3.2, 6.3.3 and IlIA 8.3.1, 8.3.2,
8.3.3 Crop Field Trial- Cottonseed and Gin Trash. DP Barcode D294542.
MRID No. 46341001.
Document (PDF) (672 KB PDF).

December 07, 2004. DER. 18 Pages.
Alex Clem. Ecological Effects Branch.
Data Evaluation Report on the anaerobic biotransformation ofthidiazuron in a water
-sediment system. MRID No. 46119602. DP Barcode: D298740. EPA Guideline: 162-3.
Document (PDF) (893 KB PDF).

December 07, 2004. DER. 29 Pages.
Alex Clem. EPA.
Data Evaluation Report on the aerobic biotransformation of thidiazuron in soil.
EPA Guideline: 162-1. DP Barcode: D298740. MRID No. 46119601.
Document (PDF) (1773 KB PDF).

December 08, 2004. DER. 2 Page(s).
Paul Chin. Reregistration Branch 1 HED.
Supplement to TXR No. 002308-DER for MRID No. 00077127. Developmental Toxicity
Study in Rats... provides a revised Executive Summary to upgrade the original DER.
Developmental Toxicity Study in Rats OPPTS 870.3700a [83-3a].
Document (PDF) (72 KB PDF).

December 09, 2004. DER. 133 Pages.
Paul Chin. Reregistration Branch I.
Thidiazuron - Reviews of Five Toxicity Studies, Updating Executive
Summaries for Four Studies and Toxicology Chapter for RED.
DP BARCODE: D294540, D294560, D307336, D300853. TXR#: 0052174.
MRID Nos. 46261502, 46261501, 46345201, 46346001, 46209601.
Document (PDF) (4219 KB PDF).

December 09, 2004. Memorandum. 100 Pages.
Paul Chin. Reregistration Branch I.
Thidiazuron - Reviews of Nine Toxicity Studies: DP BARCODE: D294559, D305092.
TXR#: 0052299. MRID 46121501, 46121502, 46121503, 46121504, 46121505, 46121506,
46121508, 46121507, 46121509, 46121510, 46241001, 46252001.
Document (PDF) (3204 KB PDF).

December 16, 2004. DER. 30 Page(s).
Paul Chin. Reregistration Branch 1 HED.
Study Type: 83-2b; Carcinogenicity Study in Mice.
Pages 21-30 removed, registrant data. MRID 46346001.
Document (PDF) (698 KB PDF).

December 16, 2004. DER. 49 Page(s).
Paul Chin. Reregistration Branch 1 HED.
Study Type: 83-5; Combined Chronic Toxicity /Carcinogenicity Study in Rats.
Pages 28-49 removed, registrant data. MRID 46345201.
Document (PDF) (929 KB PDF).

February 14, 2005. Memorandum. 15 pages.
Breann Hanson. Technical Review Branch.
Name of Pesticide Product: Thidiazuron Technical Cotton Defoliant.
EPA File Symbol: 264-IEE. DP Barcode: D312650. MRID Nos. 41426901, 42099601,
42099602, 46121501, 46121502, 46121503, 94246007, 94246009, 94246010.
Document (PDF) (472 KB PDF).

October 19, 2005. Memorandum. 32 Page(s).
Stephen Dapson. Toxicology Branch.
THIDIAZURON: Review of several developmental toxicity (teratology) study
in rats and rabbits. EPA DP Barcode: D230151; EPA Submission# S511959;
EPA MRID No.s 43853001, 00077126, 94246035 (reformat of 00077127),
0007128, 94246036 (reformat of 00077129).
Document (PDF) (943 KB PDF).

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