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Index of Cleared Science Reviews for Thiodicarb (PC Code 114501)

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Undated. Memorandum. 1 Page(s).
Thomas Edwards. Toxicology Branch.
Delayed neurotoxicity study for Larvin 500 Thiocarb
(1016-EUP-LE, 9G2152, accession no. 099223).
Document (PDF) (41 KB PDF).

Undated. Note. 8 Page(s).
Jay Ellenberger. Registration Division.
Note to Chris Chaisson. Re: Thiodicarb/Acetamide Risk Calculation for Sweet Corn.
Document (PDF) (142 KB PDF).
Attachment(s) Following:

June 06, 1983. Memorandum.
Douglas Campt. Registration Division.
Review of Thiodicarb/Acetamide Residue and Risk Data.

June 16, 1983. Letter.
J. S. Lovell. Union Carbide.
Transfer of Thiodicarb Levels in the Diet of Cows to Acetamide in Tissues and Milk.

June 16, 1983. Memorandum.
R. W. Heintzelman. Union Carbide.
Thiodicarb Meat & Milk Study - Acetamide in Liver.

June 17, 1983. Memorandum.
Alfred Smith. Residue Chemistry Branch.
PP #3F2773: Thiodicarb/Acetamide Residues and Risk Data. Submission of 5/31/83.

*End of Attachments*

Undated. Summary. 14 Page(s).
Ecological Effects Branch.
Hazard Evaluation: Wildlife and Aquatic Organisms Checklist (Thiodicarb).
Document (PDF) (336 KB PDF).

December 15, 1978. Review. 17 Page(s).
Raymond Matheny. Ecological Effects Branch.
Exp. Permit No. 1016-EUP-52 (LE) (9G2152). Larvin 500 Insecticide.
Experimental Use Permit.
Document (PDF) (133 KB PDF).

March 27, 1979. Review. 21 Page(s).
Ronald Ney. Environmental Fate Branch.
File No. 1016-EUP-LE, 962152. Larvin 50 Insecticide. Use on Cotton and Soybeans.
Document (PDF) (221 KB PDF).

May 23, 1979. Memorandum. 42 Page(s).
William Dykstra. Toxicology Branch.
Larvin 500 Insecticide; PP #9G2152; Requested Tolerances for Ethanimidothioic acid
and its Metabolites at 0.1 ppm in or on Soybean Straw and 0.4 ppm in or on Cotton.
EPA Reg. #1016-EUP-LE. Inert ingredient information on pages 1, 3 is not included.
Document (PDF) (624 KB PDF).

June 12, 1979. Memorandum. 2 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #9G2152. Larvin in Cottonseed and Soybeans. Evaluation of Analytical Method
and Residue Data. Inert ingredient information on page 1 is not included.
Document (PDF) (1609 KB PDF).

December 19, 1979. Memorandum. 22 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #9G2152. Larvin in Cottonseed and Soybeans. Evaluation of Analytical Method and
Residue Data. Inert ingredient information on pages 1, 2 and 4, and manufacturing
process information on page 3 are not included.
Document (PDF) (1609 KB PDF).

February 21, 1980. Memorandum. 21 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. #1016-EUP-LE; Larvin 500 Thiodicarb Insecticide for Cotton and
Soybeans; PP #9G2152, Application for Temporary Tolerances for Residues of
Thiodicarb and its Metabolites in or on Cottonseed at 0.4 ppm,...
Inert ingredient info on page 2 deleted.
Document (PDF) (283 KB PDF).

April 28, 1980. Memorandum. 1 Page(s).
Abraham Mittelman. Environmental Fate Branch.
Larvin EUP on Soybeans and Cottonseed.
Document (PDF) (14 KB PDF).

May 02, 1980. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. No. 1016-EUP-LE; Larvin; PP #9G2152; Caswell #900AA;
Acc. #099378, #099377.
Document (PDF) (43 KB PDF).

November 03, 1980. Memorandum. 8 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. #264-GUG; Larvin 95% Technical; for Use in Formulating Only.
Caswell #900AA. Inert ingredient information on page 1 is not included.
Document (PDF) (104 KB PDF).

November 04, 1980. Review. 16 Page(s).
J. C. Reinert. Environmental Fate Branch.
Thiodicarb. Larvin 500. Cotton/Soybeans.
Document (PDF) (355 KB PDF).
Attachment(s) Following:

October 15, 1980. Memorandum.
Clayton Bushong. Ecological Effects Branch.
Request for Estimated Environmental Concentration(s) and Fate Data for: Larvin Insecticide.

*End of Attachments*

November 05, 1980. Final Report. 65 Page(s).
Enviro Control, Inc.
Task 1R: Review of Thiodicarb.
Document (PDF) (1323 KB PDF).

November 14, 1980. Calculations. 7 Page(s).
Ecological Effects Branch.
Larvin 99% a.i. (Thiodicarb) LC50s: Fiddler Crab/Grass Shrimp/Sheepshead
Minnow/Coho Salmon/ Brook Trout/Rainbow Trout/Alga/Mysid.
Document (PDF) (84 KB PDF).

November 18, 1980. Memorandum. 6 Page(s).
Alvaro Yamhure. Ecological Effects Branch.
Request by Union Carbide for a Full Registration of their New Insecticide Product
Larvin-(Oimethyl N,N'-[thiobis [(methyl imino) carbonyloxy]] bis,-dimethylester-44%
a.i.-to be Used on Cotton and Soybeans - EPA File No. 264.
Document (PDF) (179 KB PDF).

November 21, 1980. Validation. 3 Page(s).
Alvaro Yamhure. Ecological Effects Branch.
UC 51762 - Technical Grade 99%. Thiodicarb (Larvin). Fish - Bluegill Sunfish.
96-Hour LC50.
Document (PDF) (53 KB PDF).

November 24, 1980. Review. 12 Page(s).
Alvaro Yamhure. Ecological Effects Branch.
Reg. No. 264-GUG. Larvin 500. Full Registration (FIFRA Sec. 3).
Pages 10-12 are not included - draft label.
Document (PDF) (310 KB PDF).

January 21, 1981. Memorandum. 24 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275: Thiodicarb in Cotton and Soybeans.
Evaluation of Analytical Method and Residue Data.
Inert ingredient and manufacturing process information on pages 1 and 3 are not included.
Document (PDF) (282 KB PDF).

February 17, 1981. Memorandum. 4 Page(s).
Jack Lowe. Experimental Environments Branch.
Results of Pesticide Testing by the Experimental Environments Branch, ERL, Gulf Breeze.
Document (PDF) (75 KB PDF).

February 17, 1981. Memorandum. 77 Page(s).
William Dykstra. Toxicology Branch.
EPA Reg. #264-GUE; 264-GUR; PP #0F2413, 0H5275; Larvin, Thiodicarb; Petition
Proposing Tolerances in or on Cottonseed/Hulls and Soybeans/Hulls... for Residues...
Accession #099581-96; #099598. Inert info on pages 3-4 is not included.
Tox review 00370.
Document (PDF) (1050 KB PDF).

April 30, 1981. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 264-GUG. Larvin Thiodicarb Insecticide 95% Technical.
New Chemical - Formulating Use Only, Technical Product.
Document (PDF) (48 KB PDF).

May 01, 1981. Review. 70 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. Nos. 264-341 and 264-342. Larvin 500 Thiodicarb Insecticide and Larvin 75%
WP Thiodicarb Insecticide. Use of Two Products Having AI Thiodicarb for Use on
Soybeans and Cotton. Product impurity information on pages 2-3 is not included.
Document (PDF) (719 KB PDF).

June 08, 1981. Memorandum. 1 Page(s).
William Dykstra. Toxicology Branch.
PP #0F2413/0H5275; Thiodicarb (Larvin) in/on Cotton and Soybeans. Caswell #900AA.
Document (PDF) (19 KB PDF).

June 10, 1981. Memorandum. 2 Page(s).
William Dykstra. Toxicology Branch.
PP #0F2413/0H5275; Thiodicarb (Larvin) in/on Cotton and Soybeans. Caswell #900AA.
Document (PDF) (21 KB PDF).

July 08, 1981. Memorandum. 4 Page(s).
William Dykstra. Toxicology Branch.
PP #0F2413/0H5275; Thiodicarb (Larvin) in/on Cotton and Soybeans; Addendum to Memo of 6/10/81.
Document (PDF) (39 KB PDF).

August 20, 1981. Memorandum. 5 Page(s).
William Dykstra. Toxicology Branch.
PP #0F2413; Thiodicarb (Larvin); 6-Month Dog Study. Caswell #900AA. Accession #070153.
Document (PDF) (57 KB PDF).

September 02, 1981. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
File No. 264-GUE. Thiodicarb. Protocol for Microbial Study.
Document (PDF) (32 KB PDF).

October 28, 1981. Review. 2 Page(s).
William Dykstra. Toxicology Branch.
264-EUP-AN; 264-EUP-AR; PP #2G2581, 2H5325; Larvin in/on Soybeans and Cotton.
Caswell #900AA. Accession #070397.
Document (PDF) (22 KB PDF).

December 01, 1981. Review. 8 Page(s).
Daniel Rieder. Ecological Effects Branch.
Exp. Permit Nos. 264-EUP-AN and 264-EUP-AR. Larvin 500 and Larvin 3.2.
Proposed EUP for Use on Cotton and Soybeans.
Document (PDF) (94 KB PDF).

December 02, 1981. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
File Nos. 264-EUP-AN and 264-EUP-AR. Larvin 500 and Larvin 3.2.
EUP - Use on Cotton and Soybeans.
Document (PDF) (31 KB PDF).

March 10, 1982. Memorandum. 4 Page(s).
Richard Loranger. Residue Chemistry Branch.
PP #2G2581/FAP #2H5325. Thiodicarb (Larvin) in Cottonseed and Soybeans.
Evaluation of Analytical Method, Residue Data, and Amendment of 2/26/82.
Manufacturing process and inert ingredient information on pages 2 and 3 are not included.
Document (PDF) (59 KB PDF).

March 31, 1982. Memorandum. 1 Page(s).
Sue Rathman. Toxicology Branch.
Larvin on Soybeans and Cottonseed - Resubmission - 264-EUP-AN, 264-EUP-AR, 2G2581, 2H5325.
Document (PDF) (87 KB PDF).
Attachment(s) Following:

March 09, 1982. Review. 4 Page(s).
William Dykstra. Toxicology Branch.
Larvin; 264-EUP-AR, 264-EUP-AN; PP #2G2581, 2H5325;
Larvin in/on Cotton and Soybeans. Caswell #900AA.

*End of Attachments*

April 30, 1982. Memorandum. 5 Page(s).
William Dykstra. Toxicology Branch.
Larvin; EPA Reg. No. 264-GUE, 264-GUR; PP #0F2413, 0H5275;
Larvin in/on Cotton and Soybeans. Caswell #900AA. Accession #070764.
Document (PDF) (80 KB PDF).

May 13, 1982. Memorandum. 4 Page(s).
William Dykstra. Toxicology Branch.
Larvin; EPA Reg. No. 264-GUE; 264-GUR; PP #0F2413, 0H5275;
Larvin in/on Cotton and Soybeans; Recalculation of the ADI. Caswell #900AA.
Document (PDF) (73 KB PDF).

May 14, 1982. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
File Nos. 264-GUR and 264-GUE. Larvin 500 Thiodicarb Insecticide.
Response to EFB Comments. Inert ingredient information on page 2 is not included.
Document (PDF) (79 KB PDF).
Attachment(s) Following:

June 08, 1981. Letter. 16 Page(s).
Jay Ellenberger. Insecticide-Rodenticide Branch.
Larvin 500 Thiodicarb Insecticide. Larvin Thiodicarb Insecticide 75WP.
EPA File Symbols 264-GUR and 264-GUE. Thiodicarb for Use on Cottonseed
and Soybeans... Inert ingredient information on page 1 is not included.
Pages 3-16 are not included - inerts, CFI, draft label, data.

*End of Attachments*

May 24, 1982. Memorandum. 1 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275: Thiodicarb in Soybeans and Cottonseed.
Method Trial Request.
Document (PDF) (19 KB PDF).

May 25, 1982. Memorandum. 2 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275: Thiodicarb in Soybeans and Cottonseed.
Amendment of 2/25/82.
Document (PDF) (21 KB PDF).

June 24, 1982. Review. 2 Page(s).
Willa Garner. Ecological Effects Branch.
File Nos. 264-GUE and -GUR. Larvin. Resubmission of Field Dissipation Study.
Document (PDF) (24 KB PDF).

June 29, 1982. Review. 12 Page(s).
Daniel Rieder. Ecological Effects Branch.
File Nos. 264-GUE and 264-GUR. Larvin 500: 264-GUR. Larvin 75WP: 264-GUE.
Submission of Further Data in Support of Soybeans and Cotton Uses.
Document (PDF) (140 KB PDF).

October 21, 1982. Memorandum. 11 Page(s).
Kenneth Kissler. Analytical Chemistry Section.
PP #0F2413/FAP #0H5275. Thiodicarb in Soybeans and Cottonseed.
Document (PDF) (224 KB PDF).
Attachment(s) Following:

December 01, 1979. Method.
Union Carbide Corporation.
A Method for the Determination of Thiodicarb
Residues in Soybean Seed by Gas Chromatography.

*End of Attachments*

November 04, 1982. Memorandum. 2 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275: Thiodicarb in Soybeans and Cottonseed.
Report of Method Trial.
Document (PDF) (21 KB PDF).

December 29, 1982. Memorandum. 1 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #0F2413: Thiodicarb Metabolism.
Document (PDF) (19 KB PDF).

January 14, 1983. Memorandum. 5 Page(s).
Stanley Gross. Toxicology Branch.
Review of All Data to Determine Carcinogenic Potential of Thiodicarb.
(Re: 264-GUE, 264-GUR; PP #0F2413, 0H5275; Larvin. Petition Proposing
Tolerances in or on Cottonseed/ Hulls amd Soybeans/Hulls and Straw for
Residues of Thiodicarb). Caswell #900AA.
Document (PDF) (78 KB PDF).
Attachment(s) Following:

January 12, 1983. Note to File.
Stanley Gross. Toxicology Branch.
Special Assignment on Thiodicarb.

*End of Attachments*

January 21, 1983. Review. 14 Page(s).
Ed Fite. Ecological Effects Branch.
File Nos. 264-GUE and 264-GUR. Larvin 75WP: 264-342. Larvin 500: 264-341.
Proposed Conditional Registration of Field Corn and Sweet Corn Uses.
Document (PDF) (191 KB PDF).
Attachment(s) Following:

January 19, 1983. Memorandum.
Ed Fite. Ecological Effects Branch.
Request for Estimated Environmental Concentration for Thiodicarb.

*End of Attachments*

January 24, 1983. Review. 6 Page(s).
Emil Regelman. Environmental Fate Branch.
File Nos. 264-GUR and -GUE. Larvin 500 and Larvin 75WP.
Add Use on Field Corn and Sweet Corn. Pages 3-6 are not included - draft label.
Document (PDF) (36 KB PDF).

February 04, 1983. Review. 12 Page(s).
Robert Holst. Environmental Fate Branch.
File Nos. 264-GUG & -GUE. Larvin 500 & Larvin 75 WP. New Use in Field and Sweet Corn.
Document (PDF) (108 KB PDF).

February 09, 1983. Memorandum. 9 Page(s).
Orville Paynter. Toxicology Branch.
Thiodicarb - Response to Your Memo of 1/26/83.
Document (PDF) (105 KB PDF).
Attachment(s) Following:

February 07, 1983. Memorandum.
Orville Paynter. Toxicology Branch.
Review of Acetamide Papers Regarding Oncogenic Potential.

*End of Attachments*

February 23, 1983. Memorandum. 17 Page(s).
Stanley Gross. Toxicology Branch.
Thiodicarb: Larvin 3.2 and UCLF-2. Experimental Use Application on Field and Sweet
Corn for 1983. 264-EUP-AG, 264-EUP-AU, 3G2782, 3H5375. Caswell #900AA.
Document (PDF) (262 KB PDF).
Attachment(s) Following:

March 09, 1982. Memorandum.
William Dykstra. Toxicology Branch.
Larvin; 264-EUP-AR, 264-EUP-AN; PP #2G2581, 2H5325;
Larvin in/on Cotton and Soybeans. Caswell #900AA.

*End of Attachments*

March 02, 1983. Memorandum. 13 Page(s).
Stanley Gross. Toxicology Branch.
Larvin (Thiodicarb): 3G2782. Revision of Tolerance for Corn. Caswell #900AA.
Document (PDF) (318 KB PDF).

March 07, 1983. Memorandum. 12 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP#3F2793 / FAP3H5378: Thiodicarb in Soybeans.
Evaluation of residue data and analytical method.
Document (PDF) (189 KB PDF).

May 24, 1983. Memorandum. 8 Page(s).
Bertram Litt. Toxicology Branch.
Statistical Evaluation of 1980 Acetamide Study and its Relevance to Cancer
Risks from Larvin on Cotton and Soybeans. ID #0F2413. Action Code 232.
Document (PDF) (95 KB PDF).
Attachment(s) Following:

February 08, 1983. Memorandum.
Bertram Litt. Toxicology Branch.
Low-Dose Extrapolation of Carcinogenicity of Larvin
Estimated from its Metabolite, Acetamide.

*End of Attachments*

June 07, 1983. Memorandum. 4 Page(s).
Sami Malak. Dietary Exposure Branch.
PP #3G2782/FAP 3H5375. Thiodicarb on Field and Sweet Corn.
Amendment of February 16, 1983.
Document (PDF) (44 KB PDF).

June 07, 1983. Memorandum. 4 Page(s).
Sami Malak. Residue Chemistry Branch.
PP #3G2782/FAP 3H5375. Thiodicarb on Field and Sweet Corn.
Amendment of February 16, 1983.
Document (PDF) (44 KB PDF).

June 28, 1983. Memorandum. 2 Page(s).
Christine Chaisson. Toxicology Branch.
Thiodicarb/Acetamide Residues and Corrected Risk Calculations. PP #3F2773.
Document (PDF) (45 KB PDF).

July 11, 1983. Review. 39 Page(s).
Stanley B. Gross. Toxicology Branch.
Thiodicarb--Union Carbide's Larvin. 264-GUE/264-GUR/ 3F2773/3H5372.
Registration of Larvin Technical;MRID 79474 Pages 3-4 have been deleted -inert/
impurity information Pages 25-39 have been removed - draft label information
Tox Review 003062.
Document (PDF) (1083 KB PDF).

September 02, 1983. Memorandum. 3 Page(s).
R. S. Quick. Residue Chemistry Branch.
PP #3F2773. Thiodicarb on Sweet Corn. Amendment of 5/23/83.
Document (PDF) (45 KB PDF).

December 02, 1983. Memorandum. 2 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP #3F2773: Thiodicarb in Corn. Letters of 8/4/83 and 11/1/83.
Document (PDF) (30 KB PDF).

February 23, 1984. Memorandum. 3 Page(s).
Samuel Creeger. Environmental Assessment Branch.
Thiodicarb and Use on Field and Sweet Corn.
Document (PDF) (128 KB PDF).
Attachment(s) Following:

September 02, 1981. Memo of Meeting. 1 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Thiodicarb (Larvin).

June 21, 1982. Letter. 6 Page(s).
J. S. Lovell. Union Carbide.
Larvin 500 Thiodicarb Insecticide. Larvin 75WP Thiodicarb Insecticide.
EPA File Symbols 264-GUR and 264-GUE. Pages 2-6 are not included - registrant data.

*End of Attachments*

June 12, 1984. Memorandum. 3 Page(s).
Alfred Smith. Residue Chemistry Branch.
PP#0F2413 / FAP#0H5275: PP#3F2793 / FAP#3H5378. Thiodicarb in Cotton and Soybeans.
Amendment of May 10, 1984.
Document (PDF) (41 KB PDF).

June 15, 1984. Review. 21 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 264-341. Larvin. Review Crop Rotation Data.
Pages 4-21 removed, registrant data.
Document (PDF) (43 KB PDF).

July 06, 1984. Review. 7 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. Nos. 264-378 and -379. Larvin. Response to Data Gap - Field Dissipation Study.
Document (PDF) (192 KB PDF).

July 26, 1984. Memorandum. 11 Page(s).
V. Frank Boyd. Residue Chemistry Branch.
PP#4F3013/4H5421: Thiodicarb in tomatoes. Evaluation of residue data and analytical method.
Accession #072236. Manufacturing process information on page 3 is not included.
Document (PDF) (182 KB PDF).

September 07, 1984. Memorandum. 2 Page(s).
Richard Schmitt. Residue Chemistry Branch.
PP #0F2413/0H5275: Thiodicarb in Cotton and Soybeans. Letter of 8/7/84.
Document (PDF) (26 KB PDF).

September 24, 1984. Memorandum. 13 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275 and PP #3F2793/FAP #3H5378. Thiodicarb on Cotton and Soybeans.
Amendment of August 30, 1984 (Accession No. 129074, 129075, 129077, and 129080).
Document (PDF) (134 KB PDF).

September 24, 1984. Memorandum. 2 Page(s).
Christine Chaisson. Toxicology Branch.
0F2413/0H5275/3F2793/3H5378 Thiodicarb/Larvin.
Toxicology Evaluation of "Sensitivity of Method" for Acetamide.
Document (PDF) (24 KB PDF).

October 18, 1984. Memorandum. 3 Page(s).
Michael Firestone. Residue Chemistry Branch.
Memo of Conference, 10/2/84. "Thiodicarb on Tomatoes - Discussion of Questions
Arising from RCB's 7/26/84 Review of PP#4F3013/FAP#4H5421" and "Thiodicarb on
Cotton and Soybeans - Discussion of Acetamide in Animal Commodities...
Document (PDF) (39 KB PDF).

October 26, 1984. Memorandum. 8 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275 and PP #3F2793/FAP #3H5378.
Thiodicarb on Cotton and Soybeans. Method Trial Request.
Document (PDF) (91 KB PDF).

December 06, 1984. Memorandum. 10 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275 and PP #3F2793/FAP #3H5378. Thiodicarb on Cotton and Soybeans.
Evaluation of Amendment Dated November 19, 1984 (Accession Numbers 134927, 134928,
134929, and 134930. Recorded on RD Data Review Record, Only).
Document (PDF) (101 KB PDF).

January 04, 1985. Memorandum. 3 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413 / FAP#0H5275 and PP#3F2793 / FAP#3H5378. Thiodicarb on Cotton and Soybeans.
Tolerances/ Residue Levels of Thiodicarb Plus Methomyl and Acetamide on Cotton, Soybeans,
and Animal Commodities (Accession Nos. 136929, 136930, 136931, 136933).
Document (PDF) (44 KB PDF).

January 18, 1985. Memorandum. 9 Page(s).
Ronald Thomas. Analytical Chemistry Section (RCB).
PP# 0F2413/FAP# 0H5275 PP# 3F2973/FAP# 3H5378 Thodicarb
(Acetamide/Acetonitrile) on Milk, Liver and Eggs.
Document (PDF) (81 KB PDF).

January 29, 1985. Memorandum. 3 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413 / FAP#0H5275 / PP#3F2793 / FAP#3H5378. Thiodicarb on Cotton and Soybeans.
Evaluation of Method Trial Report Dated January 18, 1985 Regarding the Analysis of
Acetamide in Liver and Acetonitrile in Milk and Eggs.
Document (PDF) (36 KB PDF).

February 04, 1985. Memorandum. 5 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413 / FAP#0H5275 and PP#3F2793 / FAP#3H5378. (RCB#s 560, 561, 562, and 563).
Thiodicarb (Larvin) on Cotton and Soybeans. Evaluation of Amendment Dated January 22, 1985
(Accession Numbers 143495, 143496, 143497 and 143498...
Document (PDF) (64 KB PDF).

February 08, 1985. Memorandum. 2 Page(s).
Michael Firestone. Residue Chemistry Branch.
January 6, 1985 Conference with Union Carbide re: RCB's 1/29/85 Review
of PP# 0F2413/FAP# 0H5275/PP# 3F2793/ FAP# 3H5378 Thiodicarb on Cotton and Soybeans.
Document (PDF) (34 KB PDF).

February 25, 1985. Memorandum. 3 Page(s).
V. Frank Boyd. Residue Chemistry Branch.
PP#4F3013/FAP#4H5421, (RCB# 390, 391) Thiodicarb on Tomatoes -A Written Rationale on
"Acetamide as a Potential Metabolite of Thiodicarb in Plants."Evaluation of Amendment dated
November 26, 1984, & a Protocol for a study of C14-acetontrile in tomato fruit.
Document (PDF) (35 KB PDF).

March 07, 1985. Memorandum. 7 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413/FAP#0H5275 and PP#3F2793/FAP#3H5378 [RCB Nos. 709, 710, 711, 712].
Thiodicarb (Larvin) on Cotton and Soybeans. Evaluation of Amendment Dated February 26, 1985
(Accession Number 146057, 146058, 146059, 146060 - Recorded...
Document (PDF) (94 KB PDF).

April 19, 1985. Memorandum. 9 Page(s).
Alan Katz. Toxicology Branch.
Larvin; Thiodicarb: Acetamide Metabolism.
Pages 7-9 removed, commercial/financial information.
Document (PDF) (90 KB PDF).

April 30, 1985. Memorandum. 3 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413/FAP#0H5275/PP#3F2793/FAP#3H5378 - Thiodicarb on Cotton and Soybeans.
Investigation of "Ubiquitous" Acetamide in Milk.
Document (PDF) (52 KB PDF).

June 21, 1985. Memorandum. 2 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP#0F2413/FAP#0H5275 and PP#3F2793/FAP#3H5378 [No RCB #].
Investigation of "Ubiquitous" Acetamide in Milk - Slippage of RD's Expedited Due Date.
Document (PDF) (26 KB PDF).

July 31, 1985. Profile. 6 Page(s).
Ecological Effects Branch.
Thiodicarb. EEB Chemical Profile.
Document (PDF) (51 KB PDF).

August 20, 1985. Memorandum. 4 Page(s).
Dallas Wright. Analytical Chemistry Laboratory (RCB).
Analysis of Milk Samples for Acetamide.
Document (PDF) (419 KB PDF).

August 30, 1985. Memorandum. 3 Page(s).
Michael Firestone. Residue Chemistry Branch.
PP #0F2413/FAP #0H5275/PP #3F2793/FAP #3H5378 [No RCB Number].
Thiodicarb on Cotton and Soybeans. Evaluation of an Analytical Chemistry Section (COB, BUD)
Report Concerning the Analysis of Milk Samples for Acetamide, a Thiodicarb Metabolite….
Document (PDF) (30 KB PDF).

May 13, 1986. Memorandum. 3 Page(s).
Joel Garbus. Residue Chemistry Branch.
EPA No. 264-343; Thiodicarb (Larvin). Revised Product Chemistry Reflecting
Altered Manufacturing Process. Accession No. 262206; RCB No. 787.
Pages 2-3 are not included - manufacturing process, inert ingredient,
and quality control procedure information.
Document (PDF) (23 KB PDF).

June 26, 1986. Review. 3 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 264-379. Larvin. Review Soil TLC Study - New Use Requested.
Document (PDF) (38 KB PDF).

January 09, 1987. Review. 22 Page(s).
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 264-379. Larvin. Union Carbide's Response to
Concerns Raised by M. Lorber on the Leaching of Thiodicarb.
Document (PDF) (187 KB PDF).
Attachment(s) Following:

September 30, 1986. Letter.
J. S. Lovell. Union Carbide.
Leaching Potential of Thiodicarb.

October 20, 1986. Note to File.
Mathew Lorber. Exposure Assessment Branch.
Leaching Potential of Thiodicarb.

*End of Attachments*

April 24, 1987. Memorandum. 4 Page(s).
V. Frank Boyd. Residue Chemistry Branch.
PP#4F3013/4H5421: Thiodicarb in tomatoes. Evaluation of a Tomato Processing Study
Submitted by Amendment of December 18, 1986. MRID #400491-01; RCB #1885.
Document (PDF) (48 KB PDF).

May 05, 1987. Review. 14 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Reg. No. 264-379. Larvin. Protocols for Field Leaching Studies.
Document (PDF) (168 KB PDF).
Attachment(s) Following:

March 06, 1987. Letter.
J. S. Lovell. Union Carbide.
Re: Agency Groundwater Policy for Thiodicarb.

*End of Attachments*

May 28, 1987. Review. 6 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
Petition No. 7F3516; EPA Reg. #264-379. RCB #2249, 2250. MRID #401704-01,
401167-05, 401167-06. Thiodicarb. Leafy Vegetables Crop Group - 30 ppm.
Document (PDF) (196 KB PDF).

June 12, 1987. Review. 37 Page(s).
Alan C. Katz. Toxicology Branch/HED (TS-769).
PP 6F3417; Thiodicarb (LARVIN) Petition for Tolerance for Almonds, Head Lettuce
and Cole Crops MRID 00159813 Pages 28-34 have been removed - registrant data
Tox Review 005934.
Document (PDF) (394 KB PDF).

June 18, 1987. Memorandum. 3 Page(s).
Joel Garbus. Residue Chemistry Branch.
EPA Reg. No. 264-379; Thiodicarb (Larvin). Amended Registration to Lower Number
of Applications and Increase PHI on Cotton in California and Arizona. No MRID Number.
RCB No. 2310. Inert ingredient information on pages 1, 2 is not included.
Document (PDF) (34 KB PDF).

August 05, 1987. Review. 4 Page(s).
Matthew Lorber. Exposure Assessment Branch.
Reg. No. 264-379. Larvin. Protocols for Field Leaching Studies.
Document (PDF) (40 KB PDF).

December 02, 1987. Memorandum. 12 Page(s).
K. Clark Swentzel. Toxicology Branch.
Thiodicarb: Two range-finding studies, in pregnant rabbits, submitted to upgrade
a previous teratogenicity study in rabbits. Pages 6-12 removed, registrant data.
Tox review 006481.
Document (PDF) (135 KB PDF).

June 24, 1988. Review. 11 Page(s).
Patrick Holden. Exposure Assessment Branch.
Reg. No. 264-379. Thiodicarb.
Review of Field Leaching Study for Thiodicarb and its Metabolite Methomyl.
Document (PDF) (286 KB PDF).

July 22, 1988. Memorandum. 13 Page(s).
Charles Trichilo. Residue Chemistry Branch.
PP#8F3578 Thiodicarb (larvin) In Or On Sweet Corn Forage and Peppers
(Acc. #403761-0, -1, -2, -3, -4; RCB #3030).
Document (PDF) (344 KB PDF).

November 02, 1988. Memorandum. 2 Page(s).
W. T. Chin. Dietary Exposure Branch.
PP#8F3578: Thiodicarb (Larvin) In Or On Sweet Corn Forage and Peppers.
Correction of Documents (Acc. #407630-00 and #407630-01; DEB #4362).
Document (PDF) (41 KB PDF).

December 19, 1988. Memorandum. 2 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3516. Thiodicarb in or on Leafy Vegetables.
Amendment of September 9, 1988. DEB #4438. HED #8-1276. MRID # 408241-00, -01.
Document (PDF) (26 KB PDF).

February 15, 1989. Memorandum. 3 Page(s).
William Anthony. Dietary Exposure Branch.
ID #264-379 [DEB #4810] [MRID #40926801]. Thiodicarb [Larvin 3.2]:
Amended Use to Permit Low Volume Spray with Vegetable Oil on Soybeans.
Document (PDF) (64 KB PDF).

April 28, 1989. Memorandum. 3 Page(s).
Kenneth Dockter. Dietary Exposure Branch.
Thiodicarb (Larvin; EPA Reg. No. 264-379) on Cotton. Amendment to Restrict
Applications and Increase PHI. MRID No. 410191-01. Branch No. 5116.
Document (PDF) (39 KB PDF).

June 12, 1989. Memorandum. 2 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
PP #7F3516. Thiodicarb in or on Leafy Vegetables. Amendment of April 6, 1989.
DEB #5237. HED #9-1310A. MRID #N/A.
Document (PDF) (36 KB PDF).

July 24, 1989. Review. 8 Page(s).
John Noles. Ecological Effects Branch.
Reg. Nos. 89-OH-04 and 89-IN-01. Larvin (Thiodicarb).
Proposed Section 18s for Slug Control in Field Corn.
Document (PDF) (59 KB PDF).

October 05, 1989. Memorandum. 6 Page(s).
W. T. Chin. Dietary Exposure Branch.
PP#8F3578: Evaluation of Acetonitrile Residues in Edible Beef Tissues and Milk
Resulting from the Use of Thiodicarb (TDC) on Sweet Corn Forage (DEB #5519).
Document (PDF) (166 KB PDF).

November 08, 1989. One-Liner. 4 Page(s).
J. Hannan. Environmental Fate & Ground Water Branch.
Thiodicarb.
Document (PDF) (53 KB PDF).

November 06, 1990. Memorandum. 8 Page(s).
Nancy Dodd. Chemistry Branch I.
PP#4F3013/FAP#4H5421 (CBTS #6971). Thiodicarb on Tomatoes.
Amendment dated 8/10/90 concerning a Tomato Processing Study. (MRID #40049101).
Document (PDF) (82 KB PDF).

December 10, 1990. CBRS Transmit. 11 Page(s).
Christine Olinger. Chemistry Branch.
Case No.: 2675 Chemical No(s).: 114501 CBRS Transmittal Sheet
for Phase 4 Reviews Data submitter(s): Rhone-Poulenc Ag Company.
Document (PDF) (153 KB PDF).

November 18, 1992. Review. 43 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: 2-Generation Reproduction Study (range- finding and definitive studies);
6(a)(2) MRID 42381301 MRID 423813-01, -02. Pages 15-17 removed, registrant data.
Tox review 009832.
Document (PDF) (707 KB PDF).

February 28, 1994. Memorandum. 34 Page(s).
David Miller. Chemistry Branch II.
Thiodicarb. Ruminant Metabolism Study (liver, kidney, muscle milk and fat)
DP Barcode: D195281; CBRS No. 12594; MRID No.: 42919601.
Document (PDF) (540 KB PDF).

June 07, 1994. Review. 78 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Mouse Carcinogenicity Study; 6(a)(2). MRID 430005-01
Tox Review 011030. Pages 34-78 removed, registration data.
Document (PDF) (525 KB PDF).

December 19, 1994. Review. 40 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Rat Combined Chronic Toxicity/Carcinogenicity Study; 6(a) (2).
MRID 43308201. Pages 22-40 have been removed - registrant data. Tox Review 011359.
Document (PDF) (354 KB PDF).

January 10, 1995. Review. 19 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: 52-week Interim Report for Rat Combined Chronic Toxicity/
Carcinogenicity Study; 6 (a) (2). MRID 434050-01. Tox Review 011378.
Document (PDF) (423 KB PDF).

March 06, 1995. Review. 47 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Metabolism Study in the Rat. MRID 41250006 and 41250007.
Pages 23-47 have been removed - registrant data. Tox Review 011436.
Document (PDF) (545 KB PDF).

May 01, 1995. Memorandum. 21 Page(s).
David Miller. Chemistry Branch II.
Thiodicarb (114501) Magnitude of the Residue and Processing Studies
in Cottonseed and Soybeans. GDLN 171-4(k) and GDLN 171-4(l).
DP Bracodes: D170048, D201191; CBRS Nos. 8761 & 13472;
MRID Nos.: 410191-01, 420437-01, 420437-02, 423309-01 & 423309-02.
Document (PDF) (350 KB PDF).

June 14, 1995. Review. 2 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Historical Control Data Supplemental Data to Rat Combined
Chronic Toxicity/Carcinogenicity Study. MRID 43596401.
Document (PDF) (50 KB PDF).

June 28, 1995. Review. 11 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Historical Control Data of Tumor Incidence in the Mouse; 4-week Oral
Toxicity Study in Mice; Additional Supplemental Data to Support Registrant's
Contention that Dose Levels in Mouse Carcinogenicity..TXR No. 011590;
MRID No. 43619301, 43611701.
Document (PDF) (208 KB PDF).

November 15, 1995. Review. 2 Page(s).
Linda L. Taylor. Toxicology Branch II.
Thiodicarb: Rat Combined Chronic Toxicity/Carcinogenicity Study; Corrigendum.
MRID 43308201.
Document (PDF) (53 KB PDF).

June 10, 1996. Memorandum. 25 Page(s).
Linda Taylor. Toxicology Branch II.
Carcinogenicity Peer Review of Thiodicarb.
Document (PDF) (349 KB PDF).

June 18, 1996. Review. 10 Page(s).
George Ghali. Health Effects Division.
RfD/Peer Review Report of Thiodicarb (Larvin) [Dimethyl N,N-(thiobis(methylimino)
carbonyloxy)bis (ethanimidothioate]. CASRN: 59669-26-0. EPA Chem. Code: 114501.
Caswell No.: 900AA.
Document (PDF) (105 KB PDF).

July 02, 1996. Review. 8 Page(s).
Linda Taylor. Health Effects Division.
Toxicology Endpoint Selection Document Thiodicarb.
Document (PDF) (59 KB PDF).

July 19, 1996. Memorandum. 16 Pages.
Linda L. Taylor. Toxicology Branch II.
THIODICARB: Review of Acute Toxicity Data. Identifying No.: 114501-000264.
DP Barcode: D226938. MRID No.: 44025501, 44025502, 44025503. Tox review No.: 011986.
Document (PDF) (381 KB PDF).

August 14, 1996. Memorandum. 11 Pages.
Linda L. Taylor. Toxicology Branch II.
Toxicology Review for the Reregistration Eligibility Document on THIODICARB.
CAS Reg No. 59669-26-0; DP Barcode D225379. MRID Nos.: 25791, 41432, 44962,
45467, 115604, 115607, 41891004, 43373201, 43784501, 44025501 to 44025503,
92185010, 92185011.
Document (PDF) (480 KB PDF).

April 10, 1997. Review. 7 Page(s).
Linda Taylor. Health Effects Division.
Toxicology Endpoint Selection Document Thiodicarb.
Document (PDF) (87 KB PDF).

April 25, 1997. Memorandum. 16 Page(s).
Brian Steinwand. Science Analysis Branch.
Dietary Exposure Analysis for Thiodicarb in Support of the
Reregistration Eligibility Decision. Attached: DRES reports.
Document (PDF) (177 KB PDF).
Attachment(s) Following:

August 01, 1997. Memorandum.
Brian Steinwand. Science Analysis Branch.
Dietary Exposure Analysis for Thiodicarb in Support of the Reregistration
Eligibility Decision Attached: DRES report of 12/18/96.

*End of Attachments*

August 14, 1997. Memorandum. 33 Page(s).
Felicia Fort. Reregistration Branch HED.
Thiodicarb - 114501: Health Effects Division Risk Characterization Document for
Extension of Time-Limited Tolerances of Thiodicarb in/on Leafy Vegetables, Cabbage,
Broccoli, and Cauliflower (PP# 7F3516). DP Barcode: D230284.
Document (PDF) (1334 KB PDF).

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