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Index of Cleared Science Reviews
Index for Merck 3535 (Pc Code 113509)
November 19, 1998. Memorandum. 33 Pages.
Carol Frazer. Biochemical Pesticide Branch.
EPA Registration No. 806-RE; Skin-So-Soft Bug Guard IR
SPF30 Moisturizing Sunblock Lotion (7.5% ethyl-3-(N-
butylacetomido)propionate); Product Chemistry; three primary
eye irritations, one primary dermal irritation, dermal
sensitization and efficacy studies (MRID Nos.
Attachment(s) following:
November 19, 1998. Memorandum.
Carol Frazer. Biochemical Pesticide Branch.
(continued)
444337-01 through 15, 444517-01 and 445121-01 and 02); Data
waiver request for acute toxicity studies; and Petitions for
approval of three components of Skin-So-Soft... Lotion
for use as inert ingredients... Pages 32-33 removed, MP/QCP.
*End of attachments*
November 19, 1998. Memorandum. 74 Pages.
Carol Frazer. Biochemical Pesticides Branch.
EPA Registration 07059-R; INSECT REPELLENT 3535; ...Acute &
Chronic Toxicity and Efficacy Studies....
MRID Nos. 442708-01 thru 40; 442979-01 thru 07 & 444824-01.
Pages 70-74 removed, product inert impurities and
product manufacturing process.
October 13, 1999. DER. 2 Pages.
Niketas Spero. Biopesticide & Pollution Prevention Div.
Field test of IR3535 efficacy as a mosquito repellent.
MRID No. 451059-05.
November 18, 1999. DER. 2 Pages.
Niketas Spero. Biopesticide & Pollution Prevention Div.
Field test of IR3535 efficacy as a mosquito repellent.
MRID No. 451059-08.
January 31, 2001. Memorandum. 2 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Skin-So-Soft Bug Guard Plus Insect Repellent Moisturizing
Sunscreen Spray; EPA Reg. No. 806-RT; Barcode No. D266470.
MRID Nos. 451059-04 thru -10.
September 28, 2001. Memorandum. 3 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Response to Avon's comments regarding efficacy studies
submitted to the Agency to support registration of
Skin-So-Soft Gentle Breeze Bug Guard Plus IR3535 Insect
Repellent Spray (EPA Reg,. No. 806-RT) & SPF15 Sunscreen
Spray (EPA Reg. No. 806-RI); Barcode D276445.
April 10, 2002. DER. 5 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Evaluation of the Efficacy of a Personal Repellent Against
Mosquitoes. MRID No. 45353304.
April 10, 2002. DER. 4 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Evaluation of the Efficacy of a Personal Repellent Against
Mosquitoes. MRID No. 45353305.
April 12, 2002. DER. 4 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Evaluation of the Efficacy of a Personal Repellent Against
Mosquitoes. MRID No. 45359104.
April 12, 2002. DER. 4 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Evaluation of the Efficacy of a Personal Repellent Against
Mosquitoes. MRID No. 45359105.
November 4, 2002. Memorandum. 5 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Review of efficacy data submitted by Avon Products, Inc. in
support of registering Avon Skin-So-Soft Bug Guard Plus
IR3535 Expedition Insect Repellents. EPA Reg. Nos. 806-ER,
806-RO & 806-EN. MRID Nos. 453533-04 -05, 06, 454767-01, -02
45474301, 45359104, thru -07, 45359006 thru -09, & 45476001.
November 4, 2002. DER. 5 Pages.
Robyn Rose. Biopesticide & Pollution Prevention Div.
Evaluation of the Efficacy of a Personal Repellent Against
Biting Midges. MRID No. 45359107.
September 21, 2004. Memorandum. 15 Pages.
Clara Fuentes. Biochemical Pesticides Branch.
Science Review of efficacy studies designed to determine
performance of formulation 24142-20(A) against mosquitoes,
biting midges, and black flies for registration 806-EU
Aerosol, containing 7.5% IR3535 active ingredient.
MRIDs 46116808 to 46116811.
October 1, 2004. Memorandum. 2 Pages.
Clara Fuentes. Biochemical Pesticides Branch.
Science Review of efficacy study designed to determine
performance of formulation No. 24142-20 (A) (Avon Skin-So-
Soft ...) against deer tick nymphs, Ixodes scapularis,
for registration of 806-EU Aerosol containing 7.5% IR3535
active ingredient. DP Barcode: 305154. MRID 46116807.
October 1, 2004. Memorandum. 13 Pages.
Nina Simeonova. Biochemical Pesticides Branch.
Secondary Review of the application for registration
of EPA File Symbol 806-EU, Avon Skin-So-Soft Bug Guard
IR3535 (R) Insect Repellent Unscented SPF15 Sunscreen Spray
Very Water Repellent. Active Ingredient 7.5% ...(Chemical
Code 113509, CAS RN 52304-36-6). Data Package 305154.
Attachment(s) following:
October 1, 2004. Memorandum.
Nina Simeonova. Biochemical Pesticides Branch.
continued.
Inert ingredient info on pages 2 and 9 not included.
Ingredient source info on page 6 not included. CSF info on
page 7 not included. Page 8 removed, manufacturing process.
MRIDs 46179801, -02. [Product chemistry, storage stability].
*End of attachments*
October 14, 2004. Memorandum. 25 Pages.
Roger Gardner. Biochemical Pesticides Branch.
beta-Alanine, N-acetyl-N-butyl, ethyl ester (IR 3535;
PC 113509): Review of Data Evaluation Reports (DERs)
on acute toxicity data waiver requests, human skin and
bovine corneal opacity and permeability (BCOP) studies
(D305154) submitted in support of...(EPA File Symbol 806-EU).
Attachment(s) following:
October 14, 2004. Memorandum.
Roger Gardner. Biochemical Pesticides Branch.
continued.
Inert ingredient info on pages 3, 4, 5 not included.
Product ingredient source info on page 24 not included.
Page 25 removed, inert ingredient information.
MRIDs 46116803, 46116805, 46116806, 46179701.
*End of attachments*
May 2, 2005. Memorandum. 4 Pages.
Carol Frazer. Biochemical Pesticides Branch.
Scientific Review of Real Time Storage Stability Studies on:
- Avon Skin-So-Soft SSS... Repellent, ...EPA Reg. No. 806-24
- Avon Gentle Breeze... Repellent... EPA Reg. No. 806-25
- Avon Gentle Breeze... Repellent... EPA Reg. No. 806-26.