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Index of Cleared Science Reviews for Diflubenzuron (Pc Code 108201)

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September 26, 1977. Memorandum. 30 Page(s).
Salvatore Biscardi. Toxicology Branch.
Application for Full Registration of Dimilin W-25... Sections 1-9.
Inert ingredient information on pages 2, 8-12, 14, and 24-25 is not included.
Quality control procedure information on page 4 is not included.
Document (PDF) (11449 KB PDF).
Attachment(s) Following:

September 26, 1977. Reviews. 39 Page(s).
Sections 10-28.

September 26, 1977. Reviews. 36 Page(s).
Sections 29-35.

Undated. Report. 22 Page(s).
U.S. Department of Agriculture.
Biological Effects of Dimilin on Vertebrates
and Other Selected Organisms.

June 10, 1977. Reviews. 39 Page(s).
Sections 5-24 (Additional Data).
Inert ingredient information on page 7 is not included.

*End of Attachments*

April 30, 1981. Memorandum. 3 Page(s).
Salvatore Biscardi. Toxicology Branch.
Review of a Study Entitled: The Effects of Dietary Administration
of Diflubenzuron to Male and Female HC/CFLP Mice for 13 Weeks.
Tox review No. 000993.
Document (PDF) (355 KB PDF).

February 18, 1982. Memorandum. 2 Page(s).
Salvatore Biscardi. Toxicology Branch.
Review of Methemoglobinemia and Sulfhemoglobinemia in Mice.
Dimilin, EPA Reg. No. 148-1268. Tox review No. 001770.
Document (PDF) (285 KB PDF).

August 15, 1983. Memorandum. 9 Page(s).
John Chen. Toxicology Branch.
Diflubenzuron 37100-8: Review of the Effect of Diflubenzuron Given by Oral
Administration with the Feed on Toxicity and Tumor Development in HC/CFLP
Mice (Interim Report 0-52 Weeks). Tox review No. 003159.
Document (PDF) (525 KB PDF).

February 13, 1984. Memorandum. 9 Page(s).
John Chen. Toxicology Branch.
Diflubenzuron 37100-8: Registrant's Request for Removing Some Precautionary
Label Statements and Review of the Lifetime Oncogenic Study of Diflubenzuron
in Rats (52-Week Interim Report). Accession Nos. 250974, 250975, 250976, 250977.
Document (PDF) (554 KB PDF).

September 07, 1984. Memorandum. 19 Page(s).
John Chen. Toxicology Branch.
Diflubenzuron 37100-8: Review of the Lifetime Oncogenic Study of
Diflubenzuron in Rats and Request for Removing Some Precautionary
Label Statements. Accession Nos. 252928, 252929, 252930, and 252931.
Tox Review 003950.
Document (PDF) (1621 KB PDF).

October 05, 1984. Memorandum. 21 Page(s).
John Chen. Toxicology Branch.
Diflubenzuron 6F1832: Review of the Lifetime Oncogenic Study of Diflubenzuron
in Mice and Request for Deleting Some Precautionary Label Statements.
Accession Nos. 253570, 253571, 253572, 253573, 253574, 253575, and 253576.
Tox Review 004075.
Document (PDF) (1356 KB PDF).

February 13, 1985. Memorandum. 6 Page(s).
Bruce Jaeger. Toxicology Branch.
Diflubenzuron (Dimilin); EPA Reg. No. 37100-8. Company Response to Rat and
Mouse Oncogenicity Data Reviews (Chen, 9/7/84 and 11/2/84). Tox review 004292.
Document (PDF) (381 KB PDF).

July 28, 1986. Memorandum. 8 Page(s).
D. Ritter. Toxicology Branch.
Dimilan - EPA Reg. #37100-8/ER/1F2507/1H5301/37100-EUP-T.
Caswell #346A. Tox Project Numbers 1493/94/95/96/97.
Tox Review #005615.
Document (PDF) (215 KB PDF).

August 13, 1986. Memorandum. 12 Page(s).
D. Ritter. Toxicology Branch.
Dimilan - EPA Reg. #37100-8/ER/1F2507/1H5301/37100-EUP-T. Dimilan 25 WP.
Caswell #346A. Tox Project Numbers 1522/23/ 24/25/26. Tox Review 005349.
Document (PDF) (404 KB PDF).

October 22, 1986. Memorandum. 7 Page(s).
D. Ritter. Toxicology Branch.
Dimilan - EPA Reg. #37100-ER/37100-EUP-T. Caswell #346A. Tox Project #2012.
Tox Review #005552. Inert ingredient information on page 4 is not included.
Document (PDF) (547 KB PDF).

March 31, 1987. Memorandum. 3 Page(s).
David Ritter. Toxicology Branch.
EPA # 37001-9; Diflubenzuron VC 90 (Dimilin). Review of Data Submitted
in Response to Registration Standard Requirements. Tox review 005798.
Document (PDF) (317 KB PDF).

December 04, 1987. Memorandum. 8 Page(s).
Bruce Jaeger. Toxicology Branch.
Dimilin 2F; Delayed Contact Hypersensitivity Study in Guinea Pigs.
Registration data is not included on pages 3-7. Tox review 006489.
Document (PDF) (417 KB PDF).

February 16, 1988. Memorandum. 7 Page(s).
C. J. Nelson. Toxicology Branch.
Dimilan (p Chloroaniline) - Interim Quantitative Risk Assessment
from an NTP Rat and Mouse Oncogenicity Study (Preliminary Data).
Document (PDF) (344 KB PDF).

November 28, 1989. Memorandum. 2 Page(s).
Henry Spencer. Toxicology Branch.
ID #37100-7: Dimilan. Registrant Request to Remove Phrase:
"Avoid Contact with Skin" on 25WP Dimilan.
Document (PDF) (75 KB PDF).

September 17, 1993. Memorandum. 3 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Issues to be Presented at the 9/20/93 Meeting of the HED
Metabolism Committee. Reregistration Case No. 0144. Chemical No. 108201.
Document (PDF) (75 KB PDF).

November 15, 1993. Memorandum. 2 Page(s).
Andrew Rathman. Chemistry Branch.
Diflubenzuron. Outcome of the HED Metabolism Committee meeting of 11/5/93.
Reregistration Case No. 0064 [sic]. Chemical No. 041401 [sic].
Document (PDF) (96 KB PDF).

February 14, 1994. Memorandum. 8 Page(s).
Reto Engler. Health Effects Division.
Risk Assessment for "Chloroanilines", and Other Carcinogenic Metabolites
Tox. Chem No 182.
Document (PDF) (594 KB PDF).

February 15, 1994. Memorandum. 6 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Issues to be Presented at the 2/22/94 Meeting of the HED Metabolism
Committee. Estimates of Residue Levels of Diflubenzuron and p-Chloroaniline to be
Used for Dietary Risk Calculations and Estimate of Dietary Risk.
Document (PDF) (438 KB PDF).

February 28, 1994. Memorandum. 2 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Outcome of the 2/22/94 Meeting of the HED Metabolism Committee.
Reregistration Case 0144. Chemical No. 108201. No MRID #. No DP Barcode. No CBRS #.
Document (PDF) (101 KB PDF).

March 21, 1994. Memorandum. 2 Page(s).
Henry Spencer. Toxicology Branch.
Estimations of metabolites of Dimilin (Diflubenzuron).
Document (PDF) (112 KB PDF).

March 22, 1994. Memorandum. 10 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Issues Presented at the 3/17/94 Meeting of the HED Metabolism
Committee. Estimates of Residue Levels of Diflubenzuron and p-Chloroaniline to
be Used for Dietary Risk Calculations and Estimate of Dietary Risk.
Document (PDF) (723 KB PDF).

March 22, 1994. Memorandum. 2 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Outcome of the 3/17/94 Meeting of the HED Metabolism Committee.
Reregistration Case No. 0144. Chemical No. 108201. No MRID #. No DP Barcode.
No CBRS #.
Document (PDF) (108 KB PDF).

May 09, 1994. Memorandum. 6 Page(s).
Steven Knizner. Chemistry Branch II.
Diflubenzuron. Response to Solvay-Duphar/Uniroyal Estimation of the Potential
Lifetime Cancer Risk to the US Population from Dietary Exposure to Diflubenzuron-
derived Para- Chloroaniline and Related Products dated April, 1994...
DP Barcode D202763
Document (PDF) (374 KB PDF).

November 28, 1994. Memorandum. 3 Page(s).
Bernice Fisher. Science Analysis Branch.
P-Chloroaniline (Dimilin Metabolite) - Quantitative Risk Q1,
(Updated) from NTP Rat Oncogenicity Study.
Document (PDF) (134 KB PDF).

November 28, 1994. Memorandum. 8 Page(s).
Lori Brunsman. Science Analysis Branch.
P-Chloroaniline Qualitative Risk Assessment Based On Charles River
Fischer 344/N Rat Oral Gavage Study.
Document (PDF) (402 KB PDF).

April 27, 1995. Memorandum. 8 Page(s).
George Ghali. RfD/QA Peer Review Committee.
RfD/Peer Reviw Report of Diflubenzuron. Tox review No. 011539.
Document (PDF) (346 KB PDF).
Attachment(s) Following:

March 08, 1995. Memorandum. 5 Page(s).
Stephanie Irene. Health Effects Division.
Diflubenzuron - Carcinogenicity in Animals.

*End of Attachments*

April 28, 1995. Memorandum. 36 Page(s).
Jeff Evans. OREB.
Occupational and Residential Exposure Assessment for the Diflubenzuron
Reregistration Eligibility Document (RED). DP Barcodes: D209025, D209030.
Document (PDF) (737 KB PDF).

May 05, 1995. Memorandum. 25 Page(s).
Edwin R. Budd. Toxicology Branch I.
Diflubenzuron, Toxicology Branch Chapter for the Reregistration
Eligibility Decision Document (RED), Reregistration Case No. 0144.
DP Barcode: D209025. Tox Review 011609.
Document (PDF) (514 KB PDF).

May 11, 1995. Memorandum. 2 Page(s).
Edwin R. Budd. Toxicology Branch I.
Diflubenzuron (Dimilin), Finalization of Dietary
Cancer Risk Assessments for RED and Registration Actions.
MRID Nos. 417209-01 and 419190-01. DP Barcode: 214662 fs.
Document (PDF) (148 KB PDF).

June 23, 1995. Memorandum. 28 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Reregistration Eligibility Document for Diflubenzuron...
(RED Chapter for diflubenzuron) (D208994).
Document (PDF) (1246 KB PDF).

June 30, 1995. Memorandum. 39 Page(s).
Linda Kutney. Environmental Fate & Effects Division.
Transmittal of EFED List A Summary Report for Diflubenzuron (Dimilin)
Chemical #108201; Case #0144. SACS Reregistration Summary Report 2.
EEB Science Chapter 3. EFGWB Science Chapter.
Document (PDF) (1506 KB PDF).

August 02, 1995. Memorandum. 3 Page(s).
Steven A. Knizer. Chemistry Branch II.
Diflubenzuron. Section 409 Tolerance for Soybean Hulls.
Document (PDF) (226 KB PDF).

February 27, 1996. Memorandum. 4 Page(s).
Jerry B. Stokes. Chemistry Branch I.
Diflubenzuron in/on Orange, Grapefruit, and Tangerine. SLN 24 (c).
Amended Use. (No MRID #'s. CBTS# 16815, DP Barcode# D222658).
Document (PDF) (323 KB PDF).

February 28, 1996. Memorandum. 12 Page(s).
Jerry B. Stokes. Chemistry Branch I.
PP#5E4499. Diflubenzuron. Geographical Expansion for use of Dimilin 25W
and Dimilin 2F Formulations in/on Rangeland Grass. Grasshopper Control.
MRID Nos. 436579-01 and -02. DP Barcode# D216357.
Document (PDF) (174 KB PDF).

April 24, 1996. Memorandum. 25 Page(s).
Anthony Maciorowski. Ecological Effects Branch.
Review of a minor use registration of Dimilin (Diflubenzuron) on rangegrass.
MRID 43665801.
Document (PDF) (599 KB PDF).

August 21, 1996. Memorandum. 5 Page(s).
Denise Keehner. Environmental Fate & Effects Division.
Division Director Concurrence for the Diflubenzuron RED (Case 0144).
Document (PDF) (229 KB PDF).

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