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Index of Cleared Science Reviews
Index for Hexazinone (Pc Code 107201)
Undated. Memorandum. 13 Page(s).
Lynnard Slaughter. Toxicology Branch.
Review of Mouse Liver Slides/Hexazinone Treated and Control
Animal Slides.
May 16, 1974. Review. 18 Page(s).
Ronald Ney. Efficacy and Ecological Effects Branch.
Environmental Chemistry Review for 3-cyclohexyl-6-
(dimethylamino)-1-methyl-s-triazine-2,4(1H, 3H)-dione
(Velpar). Permit No. 352-EXP-XXX.
Quality control procedure information on page 3 not included.
June 11, 1975. Review. 6 Page(s).
Ronald Ney. Efficacy and Ecological Effects Branch.
Reg. No. 352-GTI.
November 22, 1976. Review. 6 Page(s).
Ronald Ney. Efficacy and Ecological Effects Branch.
352-EUP-94. EUP for Control of Aquatic Weeds in Ponds.
July 7, 1978. Review. 3 Page(s).
Ronald Ney. Efficacy and Ecological Effects Branch.
352-GIT. PM Request to Identify Data Gaps for Forest Use -
New Formulation.
November 8, 1978. Review. 10 Page(s).
Ronald Ney. Environmental Fate Branch.
352-378 PP8F2119 Added Use on Sugarcane.
July 23, 1979. Review. 4 Page(s).
Herbert Manning. Environmental Fate Branch.
352-387 Resubmission of Data.
November 28, 1979. Memorandum. 10 Page(s).
John Doherty. Toxicology Branch.
Request for permanent Tolerance for Hexazinone and its
Metabolite in or on Sugar Cane. PP. 8F2119 and Amended
Reg. No. 352-378 (VELPAR Weed Killer)
Impurity info on page 2 & inert info on page 3 not included.
Tox review 002321.
June 17, 1980. Memorandum. 3 Page(s).
John Doherty. Toxicology Branch.
PP 8F2119 and EPA Reg. No. 352-378, Hexazinone Tolerance
of 0.2 ppm on Sugarcane. [rabbit teratology, 6-month
subchronic feeding, dog]
Tox review 002320.
September 10, 1980. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
352-378 Added Use on Alfalfa.
November 28, 1980. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
352-378 Resubmission with Data.
December 11, 1980. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
352-378 This Review Amends the Review of November 28, 1980.
February 23, 1981. Review. 7 Page(s).
Willa Garner. Environmental Fate Branch.
352-387 Add reforestation use to the pellet formulation.
The WP already registered for this use.
Pages 3-5 removed, draft label.
April 15, 1981. Memorandum. 4 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number: 179-IO
BO-RID V-4
Acute Tox Reviews. Acc 244555 - 244559
Tox review 000802.
June 24, 1981. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
Add Use on Rangeland.
Pages 3-4 removed, draft label.
August 11, 1981. Memorandum. 4 Page(s).
Sherell Sterling. Fungicide Herbicide Branch.
Du Pont Hexazinone Technical. EPA File Symbol 352-GOO.
Acc. 234058, 140051, 223386.
Tox review 001176.
January 27, 1982. Memorandum. 6 Page(s).
Carlos Rodriguez. Toxicology Branch.
Two-Year Feeding Study in Mice with Hexazinone (Velpar
Technical). HLO-414-81, MR-2800-001 [CASWELL No. 271AA]
Tox review 001355.
February 24, 1982. Memorandum. 16 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 352-UEN (352-UER, 352-UEE)
5% Hexazinone Liquid Concentrate
Eye irritation study. Acc 246634.
Pages 3-16 removed, draft label.
Tox review 002802.
April 5, 1982. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
352-378 add aerial application in sugarcane.
August 9, 1982. Review. 5 Page(s).
Samuel Creeger. Environmental Fate Branch.
352-378 add aerial application in sugarcane - resubmission.
August 12, 1982. Memorandum. 4 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 352-UEN
5% Hexaconazole Liquid Concentrate
Eye irritation. Acc 247803
Pages 3-4 removed, draft label.
Tox review 005385.
August 13, 1982. Memorandum. 4 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 352-399
Hexaconazole Technical
Eye and skin irritation studies. Acc 247801, 247802
Pages 3-4 removed, draft label.
Tox review 005386.
August 25, 1983. Memorandum. 8 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol: 33560-ER
Acute Tox Studies. Acc 250576 - 250579
Pages 3-8 removed, draft label.
Tox review 005074.
November 4, 1983. Memorandum. 9 Page(s).
John Chen. Toxicology Branch.
Hexazinone (E.I. duPont de Nemours & Co.) 352-378:
Review and Evaluation of Three Mutagenicity Studies
for Registration.
Accession No. 251041, 251042, 251043
Tox review 003404.
November 19, 1984. Memorandum. 3 Page(s).
John Chen. Toxicology Branch.
Hexazinone 352-378: Registrant's Response to the
TB Review Comments Regarding Mutagenicity Studies.
Tox review 004092.
July 23, 1985. Review. 12 Page(s).
Samuel Creeger. Exposure Assessment Branch.
352-378 and -392 New Rotational Crop Statement
Pages 7-10 removed, draft label.
January 9, 1987. Memorandum. 9 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 352-ULN
Velpar ULW Herbicide
Acute Tox Studies. Acc 265654
Pages 6-9 removed, draft label.
Tox review 006375.
May 6, 1988. Data Eval. Rec. 3 Page(s).
William Dykstra. Toxicology Branch.
82-1, Subchronic Oral. MRID 104976
Tox review 007205 (excerpt).
May 6, 1988. Data Eval. Rec. 10 Pages(s).
William Dykstra. Toxicology Branch.
Hexazinone: Developmental toxicity study in Rabbits
Pages 5-10 removed, registrant data.
MRID No. 00028863
supplement to *** Tox review 007205 (added pages, tables).
May 31, 1989. Review. 16 Page(s).
Henry Jacoby. Environmental Fate & Groundwater Branch.
Review protocol for leaching study
Pages 4-16 removed, registrant data.
November 2, 1989. Memorandum. 4 Page(s).
William Dykstra. Toxicology Branch.
Hexazinone - Acute oral toxicity study with
INA3674-207 in male and female rats (Hexazinone
Tecnical). MRID 412350-04
Tox review 007596.
May 9, 1990. Review. 4 Page(s).
Paul Mastradone, Ph.D. Environmental Fate & Groundwater Branch.
352-392 Dupont Velpar L
Review/verify if sufficient data exists for new uses.
September 19, 1991. Memorandum. 158 Page(s).
Esther Rinde. Health Effects Division.
Carcinogenicity Peer Review Meeting on HEXAZINONE
Pages 62-158 removed, registrant data.
Tox review 008659.
September 26, 1991. Memorandum. 6 Page(s).
Esther Rinde. Health Effects Division.
Hexazinone P Values Using Original Pathology Report
Tox review 008658.
May 22, 1992. Memorandum. 1 Page(s).
John Abbotts. Chemistry Branch II.
Hexazinone. Du Pont Company Response to the
Reregistration Standard: Animal Metabolism Data for
Goat (MRID No. 42187901). CBRS No. 9418. DP Barcode
No. D174764. (attachments not included).
June 22, 1992. Memorandum. 23 Page(s).
William Dykstra. Toxicology Branch.
Hexazinone; 6(a)(2) data; Two-Generation Rat Reproduction
Study; ID No. 107201
MRID 420665-01
Tox review 009574.
June 22, 1992. Memorandum. 23 Page(s).
William Dykstra. Toxicology Branch.
Hexazinone; ID # 107201; One Year Dog Study with
Hexazinone; Guideline 83-1
MRID 421623-01
Tox review 009575.
July 10, 1992. Memorandum. 1 Page(s).
John Abbotts. Chemistry Branch II.
Hexazinone. Du Pont Company Response to the
Reregistration Standard: Storage Stability Data for
Animal Metabolism in Poultry (MRID No. 42219301). CBRS
No. 9510. DP Barcode No. D175243. (attachment not included).
August 12, 1992. Memorandum. 25 Page(s).
Esther Rinde. Science Analysis and Coordination Branch.
Peer Review of Hexazinone.
September 14, 1992. Memorandum. 7 Page(s).
John Abbotts. Chemistry Branch II.
Hexazinone. Du Pont Company Response to the
Reregistration Standard: Storage Stability Data for
Animal Metabolism in Goat (MRID No. 42248901). CBRS
No. 9697. DP Barcode No. D176715.
Attachment(s) following:
August 6, 1992. Report. Page(s).
Acurex Environmental Corp for CB II.
Hexazinone, Task 3
Registrant's Response to Residue Chemistry Data Requirements.
February 18, 1993. Review. 10 Page(s).
Paul Mastradone. Environmental Fate & Groundwater Branch.
environmental fate studies submitted to support rere-
gistration of hexazinone for the RED (Reregistration
Eligibility Document).
February 18, 1993. Data Eval. Rec. 4 Pages(s).
G. Maske. Environmental Fate & Groundwater Branch.
Study 9; Field Soil Dissipation of Hexazinone Herbicide.
MRID 42377901. Guideline 164-1.
June 24, 1993. Memorandum. 5 Page(s).
John Abbotts. Chemistry Branch II.
Hexazinone, Reregistration. Supplemental Data on
Poultry Metabolism (MRID No. 42690601) CBRS No. 11656
DP Barcode No. D189285.
February 28, 1994. Memorandum. 23 Page(s).
Charles Frick. Chemical Coordination Branch.
The HED Chapter of the Reregistration Eligibility
Decision Document (RED) for Hexazinone
Attached are the Product Chemistry and the Human Health
Assessment...
May 25, 1994. Memorandum. 16 Page(s).
Susan Hummel. Chemistry Branch II.
Hexazinone (107201), Reregistration Case No. 0266.
Livestock Metabolism - Confirmatory Analyses Hexazinone
Tolerance Expression CB No. 13076, DPBarcode D198348,
MRID 43074201.
July 19, 1994. Memorandum. 34 Page(s).
Kathy Monk. Science Analysis and Coordination Branch.
Transmittal of EFED List A Summary report for Hexazinone
Chemical #107201; Case #0266
1. EFGWB Science Chapter
2. EEB Science Chapter
3. SACS Reregistration Summary report.
July 27, 1994. Memorandum. 14 Page(s).
Esther Rinde. Science Analysis Branch.
Carcinogenicity Peer Review of Hexazinone (2nd).