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Index of Cleared Science Reviews for Piperonyl butoxide (Pc Code 067501)
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August 14, 1975. Memorandum. 2 Page(s).
Diana Reisa. Toxicology Branch.
Dog Guard Flea and Tick Insecticide and Mosquito Repellant.
Document (PDF) (136 KB PDF).
August 27, 1978. Memorandum. 5 Page(s).
Larry Anderson. Toxicology Branch.
Ortho Hi-Power Indoor Insect Fogger (Active Ingredients: Pyrethrins, Piperonyl
Butoxide, N-Octyl bicycloheptene dicarboximide, Petroleum Distillate) - Amendment
(Label Revision) with Data, EPA Reg. No. 239-2429...Inert ingredient info on page 1
is deleted.
Document (PDF) (283 KB PDF).
August 26, 1980. Memorandum. 4 Page(s).
Cheryl Peterson. Insecticide Rodenticide Branch.
EPA Registration No. 39159-2. A-200 Pyrinate Liquid. Caswell Nos. 715, 670.
Document (PDF) (249 KB PDF).
December 05, 1980. Memorandum. 4 Page(s).
Cheryl Peterson. Insecticide Rodenticide Branch.
EPA Registration No. 4816-482. Pyrenone Garden Spray Concentrate.
Tox review
000295.
Document (PDF) (253 KB PDF).
February 13, 1981. Memorandum. 3 Page(s).
B. T. Backus. Insecticide Rodenticide Branch.
EPA File Symbol 4822-RIN. Raid Indoor Fogger II. Caswell #s 844, 652B,
715, 670, 613.
Document (PDF) (167 KB PDF).
March 12, 1981. Efficacy Review. 6 Page(s).
R. S. Van Denburgh. Insecticide Rodenticide Branch.
File No. 4822-RIN. Raid Indoor Fogger II. Registration. Inert ingredient and product
ingredient source information on pages 1-2 are not included.
Document (PDF) (257 KB PDF).
June 05, 1981. Memorandum. 5 Page(s).
Cheryl Peterson. Insecticide Rodenticide Branch.
EPA Reg. No. 4822-141. Johnson Wax Raid Formula III Flying Insect Killer.
Acc.
No. 244998. Tox review 000620.
Document (PDF) (283 KB PDF).
August 28, 1981. Memorandum. 2 Page(s).
D. Ritter. Toxicology Branch.
FAP #IH5303 - Pyrethrins, Piperonyl Butoxide and Diatomaceous Earth in Food and
Feed Handling Establishments. Amended Registration (#6300-1AA; Perma-Guard
Household Insecticide D-20). Inert ingredient information on page 2 is not included.
Document (PDF) (90 KB PDF).
March 19, 1982. Review. 2 Page(s).
R. S. Van Denburgh. Insecticide Rodenticide Branch.
Raid Indoor Fogger II. Registration. Product ingredient source information on page 1 is
not included.
Document (PDF) (80 KB PDF).
September 08, 1983. Memorandum. 3 Page(s).
B. T. Backus. Insecticide Rodenticide Branch.
EPA Reg. No. 432-686. SBP-1382/Allethrin/Piperonyl Butoxide Insecticide.
Caswell Nos. 83E, 25A, 670 Accession 252259. MRID 003222.
Document (PDF) (162 KB PDF).
October 04, 1983. Memorandum. 4 Page(s).
Phil Hutton. Insecticide Rodenticide Branch.
432-667; Scourge Insecticide; Acc No.: 250875. Acute oral LD50.
Document (PDF) (118 KB PDF).
November 01, 1983. Memorandum. 2 Page(s).
B. T. Backus. Insecticide Rodenticide Branch.
EPA Reg. No. 1021-340 Pyrocide Intermediate No. 5192 Inhalation LC50 - Rat
Acc.
251314.
Document (PDF) (76 KB PDF).
November 01, 1983. Memorandum. 3 Page(s).
William Dykstra. Toxicology Branch.
Pyrocide Intermediate 5192 EPA Registration # 1021-340 Resubmission with DATA
[Acute] Toxicity Studies (Biosearch Inc., July 1, 1975).
Document (PDF) (168 KB PDF).
March 22, 1984. Memorandum. 6 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration Number 2724-298. Zoecon RF-200 Pressurized Spray.
Document (PDF) (398 KB PDF).
July 11, 1984. Review. 2 Page(s).
Rita Kumar. Insecticide Rodenticide Branch.
IRB/TSS Precautionary Labeling Review [Reg. No.] 1021-340 Pyrocide Intermediate
5192 Inhalation, dermal sensitization Acc. 252717, 252716, 252314.
Document (PDF) (480 KB PDF).
October 11, 1984. Memorandum. 2 Page(s).
Phil Hutton. Insecticide Rodenticide Branch.
432-667; Scourge Insecticide with SBP-1382/Piperonyl Butoxide 18% + 54% Mf
Formula II. Accension No. 252817.
Document (PDF) (76 KB PDF).
June 05, 1985. Memorandum. 4 Page(s).
D. Ritter. Toxicology Branch.
EPA Reg. No. 4758-RLG. Holiday Non-Aerosol Flea Spray (d-Limonene and
Linalool as Active Ingredients and Piperonyl butoxide as Synergist).
Document (PDF) (148 KB PDF).
June 18, 1985. Efficacy Review. 7 Page(s).
R. S. Van Denburgh.
Registration (4758-RLR). Inert ingredient information on pages 3 and 6 is not included.
Document (PDF) (337 KB PDF).
June 27, 1985. Memorandum. 6 Page(s).
Irving Mauer. Toxicology Branch.
Piperonyl Butoxide - Mutagenicity Study Submitted in Response to Special Review
DCI. Accession No. 257430. Registration No. 1021-974. Caswell No. 670
Tox review 004508.
Document (PDF) (318 KB PDF).
August 23, 1985. Efficacy Review. 5 Page(s).
R. S. Van Denburgh.
Registration (4758-RLR). Inert ingredient information on pages 3-4 is not included.
Document (PDF) (204 KB PDF).
September 24, 1985. Efficacy Review. 5 Page(s).
R. S. Van Denburgh.
Flea Spray for Pets and Pet Bedding (4758-RLR, -RLG). Inert ingredient information
on pages 3-4 is not included.
Document (PDF) (227 KB PDF).
October 30, 1987. Memorandum. 6 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 4816-72 - Piperonyl Butoxide. Review of a Rat Multigeneration
Reproduction Study (1986). Accession 263635 thru 263640. Tox review 006414.
Document (PDF) (285 KB PDF).
February 25, 1988. Memorandum. 8 Page(s).
John Doherty. Toxicology Branch.
EPA File No. 067501. Piperonyl Butoxide: Review of Metabolism and
Pharmacokinetic Studies in Rats. Pages 7 and 8 removed, registrant data.
Tox review
006609.
Document (PDF) (396 KB PDF).
April 28, 1988. Memorandum. 24 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 4816-72 - Piperonyl Butoxide: Review of a Chronic
Feeding/Oncogenicity Study Submitted by the Piperonyl Butoxide Task Force.
Document (PDF) (1408 KB PDF).
Attachment(s) Following:
August 28, 1987. Study. Page(s).
Gerald Schoenig. Piperonyl Butoxide Task Force.
Discussion of Findings in a 24-Month Dietary Toxicity and Carcinogenicity Study
of Piperonyl Butoxide in the Albino Rat. MRID No. 403237-01
Tox review 006668.
*End of Attachments*
July 29, 1988. Memorandum. 2 Page(s).
Leung Cheng. Residue Chemistry Branch.
NV-880006. Section 24 (c) Registration. Diazinon and Piperonyl Butoxide in Ear
Tags. No MRID #. RCB #4080. Inert ingredient information on page 2 is not included.
Document (PDF) (144 KB PDF).
June 21, 1989. Memorandum. 12 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg. No./File Symbol 8329-GL; 8329-GU Strike 4-12 ULV; Magnum 44 ULV
Acute toxicity studies MRID 408805-02 through -07.
Document (PDF) (705 KB PDF).
December 01, 1989. Memorandum. 8 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No.: 432-667. SCOURGE Insecticide with SBP-1382
(resmethrin)/piperonyl butoxide MF Formula II and PP#9F2209, Resmethrin: ex-
emption from a tolerance... MRIDs 406958-03, -05. Tox review 007633.
Document (PDF) (511 KB PDF).
July 30, 1990. Memorandum. 8 Page(s).
Olga Odiott. Registration Support Branch, RD.
EPA Reg. No./EPA File Symbol 8329-GI ULV Mosquito Devastator 420 Acute
toxicity MRID 41493302 through -06, 41512801.
Document (PDF) (439 KB PDF).
November 14, 1991. Memorandum. 3 Page(s).
Mark Perry. Registartion Support Branch RD.
EPA File Symbol/EPA Reg. No.: 8329-UN Biomist 1.5 + 7.5 ULV...the acute
studies under EPA Reg. No 8329-38 support the registration of 8329-UN. Inert
ingredient info on page 2 not included. MRIDs 414933-02 thru -06. Inhalation study:
No MRID.
Document (PDF) (121 KB PDF).
March 23, 1993. Memorandum. 15 Page(s).
Geruva Reddy. Toxicology Branch.
Subject: EPA ID # 067501: Piperonyl butoxide. Review of Developmental Toxicity
Study in the Rat (MRID # 423808-01) Pages 13-15 removed, registrant data.
Tox review 010108.
Document (PDF) (685 KB PDF).
March 30, 1993. Memorandum. 17 Page(s).
William Woodrow. Registration Support Branch.
EPA Reg./File Symbol No.: 499-GIL. PT 230 [239] Tri Die. Six acute toxicity studies.
MRID 42613702 thru 42613707.
Document (PDF) (1053 KB PDF).
April 06, 1994. Memorandum. 13 Page(s).
John Doherty. Toxicology Branch.
EPA ID # 067501. Piperonyl butoxide: Review of a series 83-1(b) chronic feeding
study in dogs. MRID 429260-02, -01. Tox review 010885.
Document (PDF) (787 KB PDF).
May 23, 1994. Memorandum. 4 Page(s).
G. F. Kramer. Chemistry Branch I.
ID# 039039-00004. Registration of Python Insecticide Cattle Ear Tag (Cyprmethrin,
Piperonyl butoxide). MRID#s 425511-08 & -09. Barcode D185396. Case 015542.
CBTS# 11035.
Document (PDF) (215 KB PDF).
June 22, 1994. Memorandum. 32 Page(s).
John Doherty. Toxicology Branch.
EPA Id # 067501. Piperonyl butoxide. Review of a Series 82-4 subchronic
inhalation toxicity study in rats. 6(a)2 MRID 424771-01. Tox review 011066.
Document (PDF) (1326 KB PDF).
July 19, 1994. Memorandum. 6 Page(s).
Ian Blackwell. Registration Support Branch.
EPA Reg. No./File Symbol: 11540-1/ULD BP-300 Insecticide; Acute Tox One-Liner.
MRID No. 430940--1.
Document (PDF) (273 KB PDF).
January 04, 1995. Memorandum. 12 Page(s).
Lori Brunsman. Science Analysis Branch HED.
Piperonyl butoxide qualitatiove risk assessment based on Charles River Sprague-
Dawley Crl-CDR rat and Charles River CD-1 mouse dietary studies.
MRIDs 40323701, 42903701. Tox review 012767.
Document (PDF) (576 KB PDF).
January 26, 1995. Memorandum. 140 Page(s).
Esther Rinde. Health Effects Division.
Carcinogenicity Peer Review Meeting on PIPERONYL BUTOXIDE This is a Draft
Document. Information supporting an unregistered product on pages 125 and 126
is not included.
Document (PDF) (10258 KB PDF).
Attachment(s) Following:
April 28, 1988. Memorandum. Page(s).
John Doherty. Toxicology Branch I.
EPA Reg. No.: 4816-72 - Piperonyl Butoxide: Review of a chronic
feeding/oncogenicity study submitted by the Piperonyl Butoxide Task Force
MRID 403237-01. Tox review 006668.
October 29, 1993. Memorandum. Page(s).
John Doherty. Toxicology Branch I.
EPA Id# 067501. Piperonyl butoxide. Review of a series 83-2 mouse
carcinogenicity study. Evidence for liver carcinogenicity.
MRID 429037-01, 429780-01. Tox review 010647.
November 15, 1993. Memorandum. Page(s).
John Doherty. Toxicology Branch I.
EPA ID #067501. Piperonyl butoxide. 6(a)2 submission concerning a literature
report of induction of liver tumors in Fischer 344 strain rats Tox review 010658.
*End of Attachments*
June 07, 1995. Memorandum. 29 Page(s).
John Doherty. Toxicology Branch I.
Carcinogenicity Peer Review of Piperonyl Butoxide.
Document (PDF) (1960 KB PDF).
August 07, 1995. Memorandum. 16 Page(s).
Lucy Markarian. Registration Support Branch.
EPA File Symbol/EPA Reg. No.: 432-TOA Aqua-Permanone.
MRID Nos. 432237-04, -05, -06, -07, -08, -09.
Document (PDF) (982 KB PDF).
August 12, 1996. Memorandum. 21 Page(s).
Carol Glascow. Registration Support Branch.
EPA File Symbol/EPA Reg. No.: 499-450/ULD BP-300 Insecticide
(Acute Toxicity Studies).
Document (PDF) (1014 KB PDF).
September 20, 1996. Memorandum. 2 Page(s).
Carol Glascow. Registration Support Branch.
EPA File Symbol/EPA Reg. No.: 432-TOA Aqua-Permanone; Supplementary
Information for Registration.
Document (PDF) (90 KB PDF).
October 03, 1996. Memorandum. 5 Page(s).
Carol Glascow. Registration Support Branch.
EPA File Symbol/EPA Reg. No.: 432-TOA Aqua-Permanone; Submission of
Supplementary Information for Registration -- Missing Items from Earlier Review.
MRID Nos.: 440644-01 & -02.
Document (PDF) (298 KB PDF).
July 17, 1997. Review. 5 Page(s).
Alfred Smith. Technical Review Branch.
Product Chemistry Review. REG./File Symbol No.: 499-GIL. Whitmire PT 239 Tri
Die Insecticide MRID 42613701.
Document (PDF) (214 KB PDF).
March 31, 1998. Memorandum. 13 Page(s).
Masih Hashim. Technical Review Branch.
EPA Reg. No.: 4-389; Acute Toxicity One-Liners (81-1 through 81-6).
MRID Nos. 444304-01, -02, -03, -04, -05, -06. Inert Ingredient info removed from page 13.
Document (PDF) (436 KB PDF).
May 20, 1998. Memorandum. 23 Page(s).
Jane Smith. Technical Review Branch, RD.
Acute Toxicity Reviews for EPA Reg. No.: 432-667 Scourge Insecticide with
SBP-1382/PBO 18+54% MF Formula II MRIDs 431994-01 through -03.
Document (PDF) (1372 KB PDF).
December 03, 2001. Memorandum. 14 Page(s).
Eugenia McAndrew. Technical Review Branch.
Name of Pesticide Product: Evercide Synergized Permethrin Pour-On 2783.
EPA Reg. No. /File Symbol: 1021-1739. DP Barcode: D278754. Case No: 066277.
PC Code: 209500, 067501. MRID Nos. 455009-01 to -05 and 455163-01.
Document (PDF) (363 KB PDF).
May 10, 2004. Memorandum. 11 Page(s).
Jerome Blondell. Chemistry & Exposure Branch HED.
Review of Piperonyl butoxide incident Reports DP Barcode D303303,
Chemical #067501.
Document (PDF) (419 KB PDF).
January 27, 2009. Memorandum. 13 Pages.
Thurston G. Morton. Risk Assessment Branch IV.
Abamectin. Revised Review of the Section 3 Registration Request for Ear Tag Use
on Beef Cattle and Non-Lactating Dairy Cattle. EPA File Symbol: 39039-RT.
MRID Nos. 471640-11,-12,-16, 471855-02, -03, 476239-01 thru -06.
DP Barcode: 357192, 360418 & 360699
Document (PDF) (659 KB PDF).
February 04, 2009. Memorandum. 15 Page(s).
Eugenia McAndrew. Technical Review Branch.
Name of Pesticide Product: RF2042[CDSO]. EPA Reg. No./File Symbol: 2724-TOA.
DP Barcode: D357271. Decision No.: 399095.
MRID Nos.: 475185-04 to -08. (MRID 47518509).
Document (PDF) (333 KB PDF).
February 05, 2009. Memorandum. 34 Page(s).
Byron Backus. Technical Review Branch.
Name of Pesticide Product: RF 2042 [CDSO]. EPA Reg. No. /File Symbol: 2724-TOA.
DP Barcodes 357272, 359984. Decision No.: 399095. Action Code: R310.
MRID Nos. 47518510, 47578401.
Document (PDF) (1219 KB PDF).