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Index of Cleared Science Reviews for Phosmet (Pc Code 059201)

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June 06, 1979. Memorandum. 4 Page(s).
P. V. Errico. Residue Chemistry Branch.
PP #9F2188 and FAP #9H5211. Imidan in/on Cottonseed and Refined Cottonseed Oil.
Document (PDF) (281 KB PDF).

April 18, 1982. Memorandum. 6 Page(s).
Thomas Edwards. Toxicology Branch.
Request for amended pesticide product reregistration; consideration of additional data.
Inert ingredient information on page 2 not included. Tox review 001759.
Document (PDF) (240 KB PDF).

August 12, 1985. Memorandum. 3 Page(s).
Leung Cheng. Residue Chemistry Branch.
EPA Reg. No. 2724-321. Phosmet (Prolate) on Cattle. Practicality of a 21-Day PSI.
Amendment of 6/3/85. No Accession Number. RCB No. 1072.
Document (PDF) (199 KB PDF).

April 18, 1986. Memorandum. 3 Page(s).
Michael Metzger. Residue Chemistry Branch.
86-CA-16. Proposed Section 18 for the Use of Phosmet (Imidan 50 WP, EPA Reg. No. 476-1917)
on Crabapples and Ornamentals. No. 170673. RCB No. 767.
Document (PDF) (202 KB PDF).

June 20, 1986. Memorandum. 86 Page(s).
Reto Engler. Toxicology Branch.
Peer Review on Imidan (Phosmet) for Oncogenic Effects.
Document (PDF) (4180 KB PDF).

July 24, 1986. Memorandum. 11 Page(s).
Michael Metzger. Residue Chemistry Branch.
Phosmet Dietary Exposure Resulting from Residues in Apples, Citrus, Peaches and Pears.
Document (PDF) (631 KB PDF).

July 24, 1986. Memorandum. 11 Page(s).
Reto Engler. Toxicology Branch.
Toxicology Branch Peer Review Committee Draft Document on Phosmet (Imidan).
Document (PDF) (759 KB PDF).

August 28, 1986. Memorandum. 6 Page(s).
William Greear. Toxicology Branch.
Phosmet Mouse Oncogenicity Study - Response to Concerns Raised by Esther Rinde.
Document (PDF) (297 KB PDF).

September 19, 1986. Memorandum. 3 Page(s).
Leung Cheng. Residue Chemistry Branch.
2724-321. Phosmet. Residue Study Protocols. No Accession Number. RCB No. 1358.
Document (PDF) (139 KB PDF).

October 21, 1986. Memorandum. 11 Page(s).
John Quest. Toxicology Branch.
Peer Review of Phosmet (Imidan).
Document (PDF) (749 KB PDF).

November 05, 1986. Memorandum. 18 Page(s).
William Greear. Toxicology Branch.
Phosmet - Potential Oncogenicity. Tox review 005570.
Document (PDF) (1042 KB PDF).

March 19, 1987. Memorandum. 4 Page(s).
Martha Bradley. Residue Chemistry Branch.
EPA Registration Nos. 476-2217 and 476-2178 - Phosmet (Imidan) Registration
Standard - Stauffer Initiation of Data Requirements and Request for Time Extensions,
Dated December 4, 1986 and January 20, 1987 - No Accession Number - RCB Nos. 1919 and 1920.
Document (PDF) (226 KB PDF).

April 16, 1987. Memorandum. 14 Page(s).
Sami Malak. Residue Chemistry Branch.
PP #6E3425. Phosmet (Imidan) on Pistachio. Evaluation of Analytical Methods
and Residue Data. Accession No. 263587. RCB No. 1193.
Document (PDF) (851 KB PDF).

May 06, 1987. Memorandum. 4 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 476-2178. Phosmet (Imidan). Response to Registration Standard:
Submission of 3/6/87 (Re Cottonseed Processing Studies). RCB No. 2114. MRID No. 401111-01.
Document (PDF) (224 KB PDF).

May 28, 1987. Memorandum. 1 Page(s).
Martha Bradley. Residue Chemistry Branch.
Addendum to March 19, 1987 Memo. EPA Registration Nos. 476-2217 & 476-2178 -
Phosmet (Imidan) Registration Standard - Stauffer Initiation of Data Requirements and
Request for Time Extensions Dated December 4, 1986 & January 20, 1987 -...RCB Nos. 1919,1920.
Document (PDF) (56 KB PDF).

July 21, 1987. Memorandum. 4 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 476-2178. Phosmet. Corn and Potato Metabolism and Residue
Studies Required by the Registration Standard. RCB No. 2376. MRID No. None.
Document (PDF) (251 KB PDF).

August 12, 1987. Memorandum. 3 Page(s).
Sami Malak. Residue Chemistry Branch.
PP #6E3425. Phosmet (Imidan) on Pistachio. A Revised Section B. Amendments
of May 20 and July 14, 1987. No MRID Number. RCB Nos. 2505 and 2602.
Document (PDF) (121 KB PDF).

August 19, 1987. Memorandum. 3 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 476-2178. Phosmet. Protocol for a Stored Sweet Potato Residue Study.
RCB No. 2603. MRID No. None.
Document (PDF) (186 KB PDF).

September 11, 1987. Memorandum. 14 Page(s).
William Greear. Toxicology Branch.
Phosmet (Imidan) - Submission of a Mutagenicity (Micronucleus) Assay for
Evaluation - Acc. No. 401994-1. Tox Review 006465.
Document (PDF) (307 KB PDF).

September 29, 1987. Memorandum. 5 Page(s).
Gobind Makhijani. Residue Chemistry Branch.
Stauffer Chemical Company Response to the Product Chemistry Chapter of the
Phosmet Registration Standard. MRID No. 402748-01. RCB No. 2628.
Document (PDF) (180 KB PDF).

October 06, 1987. Memorandum. 3 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 476-2178. Phosmet. Protocols for Residue Monitoring Studies.
RCB No. 2798. MRID No. None.
Document (PDF) (136 KB PDF).

January 22, 1988. Memorandum. 3 Page(s).
Leung Cheng. Residue Chemistry Branch.
88-CA-11. Section 18 Specific Exemption. Phosmet on Caneberries. No MRID Number.
RCB No. 3197.
Document (PDF) (141 KB PDF).

March 02, 1988. Memorandum. 7 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. Nos. 10182-173 and 10182-224. Phosmet. Registration Standard Follow-Up:
ICI Americas Inc. Response of 1/12/88 re Plant Metabolism Studies.
RCB Nos. 3331, 3332. MRID No. None.
Document (PDF) (376 KB PDF).

July 08, 1988. Memorandum. 2 Page(s).
Stephanie Willett. Residue Chemistry Branch.
PP #8E3621. Phosmet on Crabapples. Revised Section F. No MRID Number. RCB No. 4031.
Document (PDF) (86 KB PDF).

August 08, 1988. Memorandum. 9 Page(s).
Charles Lewis. Ecological Effects Branch.
Review of Data for Phosmet Registration Standard. Daphnia magna Life Cycle (21-Day renewal)
Chronic Toxicity. MRID No. 406528-01.
Document (PDF) (553 KB PDF).

October 27, 1988. Memorandum. 3 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
EPA Reg. No. 10182-234. Phosmet. Time Extension Request for Submission of the
Nature of the Residue (Metabolism) - Livestock Studies Required by the Phosmet
Registration Standard. DEB #4487. HED #9-0150. MRID # N/A.
Document (PDF) (131 KB PDF).

February 03, 1989. Memorandum. 15 Page(s).
William Greear. Toxicology Branch.
California Department of Food and Agriculture - EPA Toxicology Review for Phosmet.
MRID Nos. 00076434, 00062649 00012555, 00063192, 00063192.
Document (PDF) (832 KB PDF).

February 14, 1989. Memorandum. 2 Page(s).
Linda Propst. Dietary Exposure Branch.
ID No. 238607. Imidan (Phosmet) Plant Metabolism Studies. Time Extension Request.
No MRID Number. DEB No. 4863.
Document (PDF) (90 KB PDF).

April 03, 1989. DER. 16 Page(s).
David Johnson. Ecological Effects Branch.
Fish early life stage-study. Early life stage toxicity of C14-Phosmet to rainbow trout (Salmo gairdneri)
in a flow through system. MRID No.: 409387-01. Pages 4-16 removed, registration data.
Document (PDF) (292 KB PDF).

May 30, 1989. Memorandum. 2 Page(s).
Linda Propst. Dietary Exposure Branch.
Proposed Metabolism Studies for Reregistration of Phosmet.
Document (PDF) (126 KB PDF).

November 18, 1992. Memorandum. 22 Page(s).
William Greear. Toxicology Branch.
Phosmet (Imidan) - Submission of a Series 83-5 Combined Chronic/
Carcinogenicity Study in Rats. MRID 419164-01. Tox review 009828.
Document (PDF) (1221 KB PDF).

December 21, 1992. Memorandum. 1 Page(s).
Lois Rossi. Reregistration Branch.
Chronic Toxicity Testing (Rodent) for Phosmet.
Document (PDF) (53 KB PDF).

January 05, 1993. Memorandum. 2 Page(s).
Marion Copley. Toxicology Branch.
Phosmet: Rat Chronic Testing Requirement.
Document (PDF) (96 KB PDF).

April 18, 1993. Memorandum. 1 Page(s).
Penelope Fenner-Crisp. Health Effects Division.
Results of the Cancer Peer Review of Phosmet.
Document (PDF) (50 KB PDF).

November 04, 1993. Memorandum. 10 Page(s).
Marion Copley. Toxicology Branch 1.
Request for a Second Peer Review of Phosmet (Imidan).
Document (PDF) (547 KB PDF).

November 16, 1993. Review Summary. 3 Page(s).
Kerry Dearfield. Health Effects Division.
Mutagenicity Review Summary.
Document (PDF) (139 KB PDF).

January 25, 1994. Memorandum. 7 Page(s).
Bernice Fisher. Science Analysis Branch.
Phosmet (Imidan Technical T-10719) B6C3F1 Mouse Oncogenicity Study,
4/81-5/83 - Qualitative Risk Assessment Revised, 1/94.
Document (PDF) (242 KB PDF).

March 07, 1994. Memorandum. 18 Page(s).
Esther Rinde. Science Analysis & Coordination Branch.
Health Effect Division Carcinogenicity Peer Review Committee
Draft Document on Phosmet (2nd).
Document (PDF) (995 KB PDF).

March 15, 1994. Tox Endpoint. 6 Page(s).
Marion Copley. Health Effects Division.
Toxicology Endpoint Selection Document MRID 40122201, 41916401, 41520001.
Document (PDF) (352 KB PDF).

March 17, 1994. Memorandum. 9 Page(s).
Yin-tak Woo. Health Effects Branch.
Carcinogenicity Peer Review Document on PHOSMET.
Document (PDF) (1158 KB PDF).

May 09, 1994. DER. 27 Page(s).
Brian Montague. Ecological Effects Branch.
29 Day Flow through Life Cycle Study with the saltwater mysid, Mysidopsis bahia.
MRID No. 42724901.
Document (PDF) (1319 KB PDF).

May 11, 1994. Memorandum. 5 Page(s).
George Ghali. Health Effects Division.
RfD/Peer Review Report of Phosmet (Imidan) [N- (mercaptomethyl) pthalimide
s-(O,O-dimethylphosphorodithioate).
Document (PDF) (404 KB PDF).

May 25, 1994. Memorandum. 20 Page(s).
Esther Rinde. Science Analysis & Coordination Branch.
Carcinogenicity Peer Review of Phosmet (2nd).
Document (PDF) (1101 KB PDF).

September 03, 1996. Memorandum. 12 Page(s).
Brian Steinwand. Science Analysis Branch.
Dietary Exposure Analysis for Synar List Chemical (Phosmet).
Document (PDF) (834 KB PDF).

April 16, 1997. Memorandum. 3 Page(s).
Virginia Dobozy. Toxicology Branch II.
Phosmet - Review of Incident Reports for Proticall Dermal-Dip.
Document (PDF) (248 KB PDF).

December 19, 1997. Memorandum. 14 Page(s).
George Ghali. Health Effects Division.
Phosmet [(mercaptomethyl)] phthalimide S-(O,O- dimethylphosphorodithioate]:
Hazard Identification Committee Report. Tox review 012449.
Document (PDF) (685 KB PDF).

December 07, 1998. Memorandum. 14 Page(s).
Jerome Blondell. Chemistry & Exposure Branch.
Review of Phosmet Incident Reports. DP Barcode D251427, Chemical #059201,
Reregistration Case #0242.
Document (PDF) (709 KB PDF).

February 03, 1999. Memorandum. 14 Page(s).
Kathleen Raffaele. Toxicology Branch.
Phosmet: Acute Neurotoxicity study [rat]. MRID No.: 44673301. Tox review 013167.
Document (PDF) (1084 KB PDF).

June 23, 1999. Memorandum. 20 Page(s).
Whang Phang. Reregistration Branch HED.
Phosmet: Review of a 90 [day] neurotoxicity study in rats. MRID 44811801.
Tox review 013522.
Document (PDF) (1311 KB PDF).

July 30, 1999. Memorandum. 8 Page(s).
Christina Swartz. Reregsitration Branch HED.
Phosmet. (Chemical ID No. 059201/List A Reregsitration Case No. 0242). HED Review of
the Gowan Probabilistic (Monte Carlo) Acute Dietary Exposure and Risk Assessment.
MRID Nos. 44771101 and 44771102. DP Barcode No. D254657.
Document (PDF) (616 KB PDF).

August 18, 1999. Memorandum. 102 Page(s).
Sanjivani Diwan. Health Effects Division.
Cancer Assessment Review Committee on Phosmet. Pages 68-75 removed, registration data.
Document (PDF) (4765 KB PDF).
Attachment(s) Following:

July 15, 1986. Memorandum.
William Greear. Toxicology Branch.
Imidan (Phosmet) Mouse Oncogenicity Study - Stauffer Report No. T-10719
EPA Registration No. 476-2178 (Accession Nos. 254608 and 254609). Tox review 005304.

February 13, 1992. DER.
Sanju Diwan. Clement International for HED.
Metabolism in Rats MRID 412960-01, 414257-01.

August 17, 1999. Memorandum.
Linda Taylor. Reregistration Branch, HED.
PHOSMET: Modified Data Package For Determining the Appropriate Means for
Quantifying Human Cancer Risk.

*End of Attachments*

October 27, 1999. Memorandum. 10 Page(s).
Sanjivani Diwan. Health Effects Division.
Phosmet - Report of the Cancer Assessment Review Committee Evaluation of the
Carcinogenic Potential of Phosmet (Third Review) Tox review 013815.
Document (PDF) (422 KB PDF).

December 09, 2008. Memorandum. 12 Pages.
Linda Taylor. Reregistration Branch I.
EPA's Response to the Questions and Issues Submitted by Gowan Regarding
MRID 47262502 (Memo: 10-14-2008 and e:mail of 11-6-2008). MRID No.: None.
DP Barcode: D296590. TXR No.: 0055037. CAS No.: 732-11-6.
Document (PDF) (952 KB PDF).

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