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Index of Cleared Science Reviews for Fonofos (Pc Code 041701)

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Undated. Memorandum. 2 Page(s).
Richard Balcomb. Ecological Effects Branch.
Estimated Aquatic Residues of Fonofos.
Document (PDF) (94 KB PDF).

Undated. Memorandum. 4 Page(s).
Richard Balcomb. Ecological Effects Branch.
Fonofos Standard - Branch Chief Review.
Document (PDF) (272 KB PDF).

Undated. Notes. 8 Page(s).
OPP. EPA.
Environmental Data Scientific Sheet No. 2.
Document (PDF) (2882 KB PDF).

Undated. Review. 2 Page(s).
Charles Bowen. Ecological Effects Branch.
Sport Fishery Investigations.
Document (PDF) (98 KB PDF).

April 27, 1970. Memorandum. 6 Page(s).
G. E. Whitmore. Petitions Review Branch.
Dyfonate residue tolerance request PP# 0F0960 Two year rat feeding study.
Two year dog feeding study. Three generation rat reproduction study.
Tox review 000631.
Document (PDF) (307 KB PDF).

April 09, 1976. Report. 21 Page(s).
William Burnam. Toxicology Branch.
Position Paper on Dyfonate. Manufacturing process information on page 3 is
not included. Commercial/financial information on pages 10-11 is not included.
Document (PDF) (1638 KB PDF).

February 27, 1979. Memorandum. 1 Page(s).
John Doherty. Toxicology Branch.
Registration No. 476-1995. Meeting with Stauffer Chemical Company Concerning
Acute Oral LD50 of Dyfonate 10G. Caswell No. 454B.
Document (PDF) (50 KB PDF).

February 28, 1979. Memorandum. 2 Page(s).
Edward Brittin. Residue Chemistry Branch.
Registration Nos. 476-2056 (-2134) [Stauffer/Dyfonate Formulations].
An Amendment to Reduce the Pre-Harvest Interval on Sorghum.
Document (PDF) (160 KB PDF).

March 13, 1979. Review. 2 Page(s).
Richard Balcomb. Ecological Effects Branch.
Review Large Pen Avian Field Study.
Document (PDF) (59 KB PDF).

December 04, 1980. Memorandum. 4 Page(s).
Edward Zager. Residue Chemistry Branch.
EPA Reg. No. 476-2028. Dyfonate on Cole Crops, Sugarcane.
Document (PDF) (237 KB PDF).

December 04, 1980. Memorandum. 4 Page(s).
Edward Zager. Residue Chemistry Branch.
EPA Reg. No. 476-2056. Dyfonate on Cole Crops, Sugarcane and Onions.
Document (PDF) (225 KB PDF).

December 04, 1980. Memorandum. 4 Page(s).
Edward Zager. Residue Chemistry Branch.
EPA Reg. No. 476-2134. Dyfonate on Cole Crops, Sugarcane and Onions.
Document (PDF) (243 KB PDF).

December 29, 1980. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
Remove Rotational Restriction - Onions.
Document (PDF) (114 KB PDF).

December 30, 1980. Review. 2 Page(s).
Willa Garner. Environmental Fate Branch.
Remove Rotational Restriction - Onions.
Document (PDF) (44 KB PDF).

January 14, 1981. Review. 4 Page(s).
Willa Garner. Environmental Fate Branch.
Removal of Rotational Crop Restriction - Onions.
Document (PDF) (148 KB PDF).

February 26, 1981. Memorandum. 4 Page(s).
Richard Balcomb. Ecological Effects Branch.
Classification of Dyfonate Granular Insecticide.
Document (PDF) (134 KB PDF).

April 06, 1981. Memorandum. 10 Page(s).
Ray Landolt. Toxicology Branch.
Pesticide Use Classification of Fonofos (Dyfonate) 20%G Pesticide
Use Restriction 44 FR 45218; ID Notification OPP-30029.
Document (PDF) (646 KB PDF).

July 15, 1981. Review. 8 Page(s).
Richard Balcomb. Ecological Effects Branch.
Proposed Label Amendments Adding Lesser Cornstalk Borer to the Corn
(Field, Sweet, and Popcorn) Use.
Document (PDF) (317 KB PDF).

July 21, 1981. Memorandum. 30 Page(s).
Ray Landolt. Toxicology Branch.
Pesticide Use Classification of Fonofos (Dyfonate) 20G Pesticide Use
Restrictions 44FR 45218 ID Notification OPP 30029 February 17, 1981
Addendum to October 26, 1979 and October 23, 1980 Comments Accession No. 244376.
Document (PDF) (1168 KB PDF).

September 25, 1981. Memorandum. 9 Page(s).
Ray Landolt. Toxicology Branch.
Pesticide Use Classification of Fonofos (Dyfonate) 20G Pesticide Use
Restrictions 44FR 45218 ID Notification OPP-30029-Letter of May 4, 1981
Addendum to October 26, 1979, October 23, 1980 and February 17, 1981 Acute
Toxicity Data Submitted by Stauffer.
Document (PDF) (358 KB PDF).

June 01, 1982. Report. 7 Page(s).
Robert O'Brien. Economic Analysis Branch.
Preliminary Quantitative Usage Analysis of Fonofos.
Commercial/financial information on pages 3-4 is not included.
Document (PDF) (187 KB PDF).

July 15, 1982. Data Eval. Rec. 71 Page(s).
Richard Balcomb. Ecological Effects Branch.
Fonofos.
Document (PDF) (2831 KB PDF).

July 28, 1982. Report. 22 Page(s).
David Thomas. Animal Sciences & Index Branch.
Registration Standard's Phase I Qualitative Use Assessment for Fonofos (041701).
Document (PDF) (1335 KB PDF).

September 15, 1982. Memorandum. 10 Page(s).
M. Nelson. Residue Chemistry Branch.
PP #2F2716/FAP #2H5359. Dyfonate in or on Potatoes.
Evaluation of Analytical Methodology and Residue Data.
Document (PDF) (581 KB PDF).

December 14, 1982. Review. 4 Page(s).
Edwin Budd. Health Effects Division.
Pesticide Petition No(s): 2F2716 / 2H5359 Increase existing tolerance
for whole potatoes from 0.1 ppm to 0.2 ppm. Establish food additive
regulation for potato waste (peels) at 3.0 ppm.
Document (PDF) (143 KB PDF).

February 16, 1983. Memorandum. 16 Page(s).
Allen Vaughan. Ecological Effects Branch.
Registration Standard for Fonofos - Nontarget Insect Studies.
Document (PDF) (786 KB PDF).

February 24, 1983. Final Report. 10 Page(s).
Dynamac Corporation.
Fonofos - Task 2: Environmental Fate and Exposure Assessment.
Document (PDF) (441 KB PDF).

February 24, 1983. Final Report. 53 Page(s).
Dynamac Corporation.
Fonofos - Task 1: Review and Evaluation of Individual Studies.
Document (PDF) (2091 KB PDF).

June 01, 1983. Summary. 1 Page(s).
Chris Chasson. Toxicology Branch.
Summary of Toxicology Branch Opinion of Stauffer Chemical Co Proposal
for Evaluating the Hazards of Granular Formulations.
Document (PDF) (47 KB PDF).

June 23, 1983. Memorandum. 7 Page(s).
Edwin Budd. Toxicology Branch.
#476-1994 Dyfonate - Mouse Teratology Study; EPA Accession No. 248893.
Document (PDF) (833 KB PDF).

July 22, 1983. Memorandum. 25 Page(s).
P. R. Datta. Exposure Assessment Branch.
Estimated Environmental Concentrations (EEC) for Dyfonate (Fonofos)
by the SWRRB, EXAM 50, and EXAM Pulse Models.
Document (PDF) (1169 KB PDF).

June 13, 1984. Memorandum. 7 Page(s).
Martha Bradley. Residue Chemistry Branch.
Accession No. 072376 PP#2F2716/2H5329. Dyfonate in or on potatoes.
Amendment of 2/21/84.
Document (PDF) (444 KB PDF).

December 18, 1984. Review. 5 Page(s).
Lionel Richardson. Exposure Assessment Branch.
Reg./File No.: 476-2134 (Page 2) Response to Stauffer's fonofos Re-entry
Labeling Requirement (132-1) (9/17/84 letter) and Registration Standard
Re-entry Letter of October 8, 1984.
Document (PDF) (275 KB PDF).

January 16, 1985. Review. 4 Page(s).
Lionel Richardson. Exposure Assessment Branch.
Response to Stauffer's Fonofos Reentry Labeling Requirement (132-1)
(9/17/84 Letter) and Registration Standard Reentry Letter of October 8, 1984.
Document (PDF) (192 KB PDF).

February 19, 1985. Memorandum. 2 Page(s).
Edwin Budd. Toxicology Branch.
EPA Reg. No. 476-2134. Dyfonate (Fonofos).
Registrant's Response to Registration Standard. Tox Review No. 004302.
Document (PDF) (203 KB PDF).

April 12, 1985. Review. 4 Page(s).
Carolyn Offutt. Exposure Assessment Branch.
Review of Protocol for Gathering Data to Assess Human Exposure and Reentry
Interval for Fonofos after its Application to Turf or Corn.
Document (PDF) (191 KB PDF).

June 04, 1985. Memorandum. 8 Page(s).
W. T. Chin. Residue Chemistry Branch.
PP #2F2716 (RCB #758) (Acc. #072376, 2/22/84). Re-Evaluation of the 14C-Fonofos
Goat Metabolism Study.
Document (PDF) (395 KB PDF).

October 31, 1985. Memorandum. 2 Page(s).
M. Sochard. Toxicology Branch.
EPA No. 476-2134. Dyfonate (Fonofos). Registrant's Response to Registration
Standard (RS) [teratology data gap].
Document (PDF) (80 KB PDF).

April 29, 1986. Review. 3 Page(s).
Reto Engler. Health Effects Division.
Reference Doses (RFDs) for Oral Exposure.
Document (PDF) (223 KB PDF).

January 06, 1987. Memorandum. 3 Page(s).
Michael Metzger. Residue Chemistry Branch.
Fonofos (Dyfonate 20-G, EPA Reg. No. 476-2028) on Sugar Beets and Corn.
No Acc. Number. RCB #1691.
Document (PDF) (176 KB PDF).

January 20, 1987. Memorandum. 3 Page(s).
Linda Propst. Residue Chemistry Branch.
Fonofos (Dyfonate 10-G, EPA Reg. No. 476-1995) on Sorghum (Milo).
Amended Registration. Accession No. 400035-01. RCB No. 1694.
Document (PDF) (169 KB PDF).

January 20, 1987. Memorandum. 3 Page(s).
Linda Propst. Residue Chemistry Branch.
Fonofos (Dyfonate 20-G, EPA Reg. No. 476-2028) on Sorghum (Milo).
Amended Registration. Accession No. 400036-01. RCB No. 1692.
Document (PDF) (159 KB PDF).

April 08, 1987. Memorandum. 2 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 476-2134. Fonofos (Dyfonate). Request for Time Extension
for Submission of the Report of Studies Required under FIFRA 3(c)(2)(B).
RCB No. 2117. MRID/Acces. No.: None.
Document (PDF) (127 KB PDF).

May 26, 1987. Review. 2 Page(s).
John Noles. Ecological Effects Branch.
Time Extension Request Relative to Submission of Data for Registration Standard.
Document (PDF) (84 KB PDF).

December 06, 1988. Review. 3 Page(s).
James Akerman. Ecological Effects Branch.
File No. 34704-EUP-RR. UAP 307 (Dyfonate and Phorate). Proposed EUP for Use
of New Granular Formulation Containing Dyfonate and Phorate on Potatoes.
Document (PDF) (133 KB PDF).

August 21, 1989. Memorandum. 5 Page(s).
Freshteh Toghrol. Dietary Exposure Branch.
Fonofos (Dyfonate 20-G and Dyfonate 10-G) on Sugar Beets.
Amendment of 5/26/89 (Removal of Geographical Restriction, Evaluation of Residue Data).
EPA Reg. No. 10182-180 and EPA Reg. No. 10182-135.
MRID #40150106. DEB #s 5420 and 5421.
Document (PDF) (259 KB PDF).

August 26, 1989. Memorandum. 9 Page(s).
William Smith. Dietary Exposure Branch.
Fonofos Registration Standard. Response by ICI Americas, Inc. Qualitative Nature
of the Residue in Ruminants and Poultry. MRIDs 40657501 and 40749501. DEB No. 5401.
Document (PDF) (447 KB PDF).

December 05, 1989. Memorandum. 5 Page(s).
Freshteh Toghrol. Dietary Exposure Branch.
Fonofos (Dyfonate) on Processed Sugar Beet Products. Amendment to Remove
Geographical Restriction. EPA Reg. No. 10182-180 and EPA Reg. No. 10182-135.
MRID #406204-03. DEB #s 5845 and 5846.
Document (PDF) (284 KB PDF).

July 12, 1990. DER. 8 Pages.
Mark Roberts. Ecological Effects Branch.
Early Life Stage Test with Freshwater Fish Species Tested: Salmo gairdneri
(rainbow trout). Accession Number 403750-01.
Document (PDF) (543 KB PDF).

June 05, 1991. Memorandum. 10 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos. Review of Submitted In Vitro Cytogenics Assay for Reregistration
(84-2) Accession Number 418371-01 Pages 7-10 removed, registrant data.
Tox review 008395.
Document (PDF) (358 KB PDF).

November 05, 1991. Memorandum. 18 Page(s).
Pamela Hurley. Toxicology Branch.
1E04021. Dyfonate 4-EC and Dyfonate 10G Granular (Fonofos) Insecticide.
Interregional Research Project No. 4 (IR-4) Petition For Tolerance In or On Muskmelon.
Document (PDF) (1196 KB PDF).

November 07, 1991. Memorandum. 14 Page(s).
Pamela Hurley. Toxicology Branch.
1E04022. Dyfonate 4-EC (Fonofos) Insecticide. Interregional Research
Project No. 4 (IR-4) Petition For Tolerance In or On Squash.
Document (PDF) (809 KB PDF).

November 07, 1991. Memorandum. 18 Page(s).
Pamela Hurley. Toxicology Branch.
Dyfonate. Review of Oncogenicity Study in Mice. MRID 401501-21
Tox review 008784.
Document (PDF) (974 KB PDF).

November 07, 1991. Memorandum. 19 Page(s).
Pamela Hurley. Toxicology Branch.
Dyfonate. Review of Chronic/Oncogenicity Feeding Study in Rats.
MRID 406179-01. Tox review 008785.
Document (PDF) (1110 KB PDF).

November 12, 1991. Memorandum. 17 Page(s).
Pamela Hurley. Toxicology Branch.
627. Dyfonate. Review of Rabbit Developmental Toxicity Study.
MRID 401501-22. Tox review 008801.
Document (PDF) (876 KB PDF).

November 12, 1991. Memorandum. 17 Page(s).
Pamela Hurley. Toxicology Branch.
Dyfonate. Review of Chronic Feeding Studies in Dogs.
MRID 00822-33. Tox review 008806.
Document (PDF) (888 KB PDF).

November 12, 1991. Memorandum. 38 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos. Data Call-In. Review of Submitted Mutagenicity Studies.
Pages 8-14, 19-37 removed, registrant data.
MRID 418133-01, 417962-01 Tox review 008808.
Document (PDF) (784 KB PDF).

November 12, 1991. Memorandum. 8 Page(s).
Pamela Hurley. Toxicology Branch.
627. Dyfonate. Review of Acute Inhalation Study.
MRID 419359-01. Tox review 008799.
Document (PDF) (536 KB PDF).

November 26, 1991. Memorandum. 10 Page(s).
Pamela Hurley. Toxicology Branch.
627. 041701. Fonofos. Review of Submitted Amendment to Mouse
Developmental Toxicity Study Accession No. 248893 Tox review 008851.
Document (PDF) (657 KB PDF).

April 15, 1992. Memorandum. 19 Page(s).
Pamela Hurley. Toxicology Branch.
627. Dyfonate. Review of 90-Day Delayed Neurotoxicity Study in Hens.
Pages 18-19 removed, registrant data. MRID 401501-20 Tox review 009430.
Document (PDF) (935 KB PDF).

April 16, 1992. Memorandum. 3 Page(s).
Pamela Hurley. Toxicology Branch.
635. Fonofos. Review of Acute and Subchronic Neurotoxicity Testing Protocols.
Document (PDF) (145 KB PDF).

May 06, 1992. Memorandum. 3 Page(s).
Pamela Hurley. Toxicology Branch.
635. Fonofos. Additional Correspondence on Acute and Subchronic Neurotoxicity
Testing Protocols and Request for Deferral on Occular Effects Testing.
Document (PDF) (176 KB PDF).

August 13, 1992. Memorandum. 2 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos. Response to Registrant Comments on Review of Acute and
Subchhronic Neurotoxicity Testing Protocols.
Document (PDF) (92 KB PDF).

August 27, 1992. Memorandum. 8 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Dyfonate. Review of Supplemental Data on Rabbit Developmental
Toxicity Study Tox review 009706.
Document (PDF) (576 KB PDF).

March 30, 1993. Memorandum. 2 Page(s).
Pamela Hurley. Toxicology Branch.
627. Fonofos. Request for Preliminary Toxicology Review of Significant
Metabolites from Confined Accumulation Study on Rotation Crops.
Document (PDF) (76 KB PDF).

April 01, 1993. Memorandum. 40 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos. Comments on the Hazard Associated With Exposure to Fonofos
or Its Degradates in Groundwater.
Document (PDF) (1838 KB PDF).
Attachment(s) Following:

March 27, 1991. Memorandum.
Peg Perreault. Occupational and Residential Exposure Br.
In-Depth Review of Postapplication/Reentry and Applicator Exposure Monitoring
Data Submitted to Support the Reregistration of Fonofos (HED Project #0-0978).

August 13, 1991. Memorandum.
Bruce Kitchens. Occupational and Residential Exposure Br.
Check Requested Label Revision for Dyfonate Granular turf
Insecticide (HED Project # 1-1428).

September 28, 1992. Memorandum.
Bruce Kitchens. Occupational and Residential Exposure Br.
Evaluate request to remove the 24-Hour Restricted Reentry Interval Statement
from the Label of Dyfonate-Tillam 1-4E for the Active Ingredient Fonofos
EPA Reg. No. 010182-00195.

October 29, 1992. Memorandum.
Linda Fisher. Office of Pesticide Programs.
Decisions on the Ecological, Fate and Effects Task Force.

*End of Attachments*

April 30, 1993. DER. 27 Pages.
Rosemary Graham Mora. KBN Engineering & Applied Sciences Inc.
72-4. Daphnia magna Life-Cycle (21-Day Renewal) Chronic Toxicity Test.
Species Tested: Daphnia magna. MRID No. 426873-01.
Document (PDF) (1054 KB PDF).

August 10, 1993. Memorandum. 6 Page(s).
Pamela Hurley. Toxicology Branch.
627. Fonofos (Dyfonate). Review of Dermal Sensitization Study.
MRID 428426-01. Tox review 010480.
Document (PDF) (324 KB PDF).

August 17, 1993. Memorandum. 14 Page(s).
Pamela Hurley. Toxicology Branch.
107201. Fonofos (Dyfonate). Corn Cluster Project.
Draft Toxicology Chapter in the Form of a RED.
Document (PDF) (764 KB PDF).

August 17, 1993. Memorandum. 22 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos (Dyfonate). Rereview of Multigeneration Reproduction Study
MRID 00082234. Tox review 010498.
Document (PDF) (1231 KB PDF).

August 19, 1993. Memorandum. 15 Page(s).
Pamela Hurley. Toxicology Branch.
627. Fonofos (Dyfonate). Review of Submitted Acute and Subchronic Mammalian
Neurotoxicity Studies. MRID 427778-01, 427926-01. Tox review 010502.
Document (PDF) (1596 KB PDF).

November 10, 1993. Memorandum. 8 Page(s).
George Ghali. Health Effects Division.
Fonofos : RfD/Peer Review Report.
Document (PDF) (756 KB PDF).

June 02, 1994. Memorandum. 51 Page(s).
Pamela Hurley. Toxicology Branch.
Fonofos (Dyfonate). Review of Supplemental Data Submitted
on Acute and Subchronic Mammalian Neurotoxicity Studies
MRID 430133-01 thru 05. Tox review 011013.
Document (PDF) (2455 KB PDF).

October 05, 1995. Memorandum. 16 Page(s).
Pamela Hurley. Toxicology Branch.
2F02716. Fonofos. Request for Tolerance Increase for Fonofos on Potatoes.
Document (PDF) (659 KB PDF).

November 03, 1995. DER. 12 Pages.
William Erickson. Ecological Effects Branch.
FISH EARLY LIFE-STAGE TEST GUIDELINE 72 - 4 (A). Fonofos: chronic toxicity
to sheepshead minnow (Cyprinodon variegatus) embryos and larvae.
MRID No. 436323-01.
Document (PDF) (902 KB PDF).

November 07, 1995. DER. 13 Pages.
William Erickson. Ecological Effects Branch.
ACUTE INVERTEBRATE LIFE-CYCLE TEST GUIDELINE 72-4B. Chronic toxicity
of fonofos to the mysid, Mysidopsis bahia. MRID No.: 436876-01.
Document (PDF) (994 KB PDF).

January 31, 1996. Memorandum. 2 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos (Dyfonate). Re-evaluation of the Eye Irritation Study.
Accession 245491, 0007877 Tox review 011774.
Document (PDF) (112 KB PDF).

April 10, 1996. Memorandum. 22 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos. Review of Chronic Dog Study (83-1(b)) for Reregistration.
MRID No. 43914601. Tox review 011881.
Document (PDF) (1309 KB PDF).

May 28, 1996. Memorandum. 7 Page(s).
Brian Steinwand. Science Analysis Branch.
Dietary Exposure Analysis for Fonofos in/on Potataoes (PP# 2F2716).
Document (PDF) (410 KB PDF).

July 08, 1996. Memorandum. 4 Page(s).
George Ghali. Health Effects Division.
Fonofos: Reconsideration of the Reference Dose.
Document (PDF) (180 KB PDF).

August 12, 1996. Review. 10 Page(s).
Pamela Hurley. Health Effects Division.
Toxicology Endpoint Selection Document Fonofos.
Document (PDF) (487 KB PDF).

September 03, 1996. Memorandum. 20 Page(s).
Pamela Hurley. Toxicology Branch.
041701. Fonofos (Dyfonate). Draft Toxicology Chapter
For Reregistartion Eligibility (Page 3 Hazard Assessment).
Document (PDF) (877 KB PDF).

October 27, 1997. DER. 73 Pages.
Rosemary Graham Mora. KBN Engineering & Applied Sciences Inc.
FISH LIFE-CYCLE TOXICITY TEST GUIDELINE 72-5. FONOFOS: Determination of
Chronic Toxicity to Fathead Minnow (Pimephales promelas) Full Lifecycle.
MRID No.: 442032-01. DP Barcode: D233223.
Document (PDF) (3335 KB PDF).

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