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Index of Cleared Science Reviews for Disulfoton (Pc Code 032501)
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Undated. DER. 13 Pages.
Louis Scarano. Toxicology Branch.
Non-guideline; Time of Peak Cholinesterase Inhibition and Comparative Cholinesterase
Studies in Preweaning and Young-adult Rats. Work Assigmnent No. 3-01-80; formerly
2-01-80 (MRIDs 46589701 through 46589704). DP BARCODE: DP319813.
Document (PDF) (461 KB PDF).
March 29, 1982. Memorandum. 2 Page(s).
Roger Gardner. Toxicology Branch.
Review of a Mutagenicity Study on Di-Syston. EPA Reg. No. 3125-183.
Acc. No. 246161. Tox Chemical No. 341.
Document (PDF) (122 KB PDF).
December 20, 1983. Final Report. 57 Page(s).
Dynamac Corporation for EFED.
Disulfoton. Task 1: Review and Evaluation of Individual Studies (studies 1 thru 14)
MRIDs 95651, 92972, 95664, 65859, 94227, 52094, 52092, 73113, 68214, 79801, 68096,
95652, 36250, 103661.
Document (PDF) (2401 KB PDF).
January 11, 1984. Final Report. 10 Page(s).
Dynamac Corporation.
Disulfoton. Task 2: Environmental Fate and Exposure Assessment.
Document (PDF) (513 KB PDF).
March 13, 1984. Memorandum. 3 Page(s).
George Ghali. Toxicology Branch.
EPA Reg. No. 3125-183; Di-Syston; Micronucleus test in the mouse (IBT replacement).
Caswell No. 341; Access. No.: 250895.
Document (PDF) (144 KB PDF).
April 01, 1984. Memorandum. 239 Page(s).
George Ghali. Toxicology Branch.
Transmittal of Disulfoton (Di-Syston) Registration Standard
Inert ingredient information on pages 24 and 67 not included. Tox review 003958.
Document (PDF) (11174 KB PDF).
April 05, 1984. Science Chapter. 20 Page(s).
Ed Fite. Ecological Effects Branch.
Disulfoton Registration Standard.
Document (PDF) (873 KB PDF).
October 30, 1984. Memorandum. 9 Page(s).
Christine Chaisson. Toxicology Branch.
EPA Reg. No. 3125-58; Disulfoton (Di-Syston) Embryotoxic and Teratogenic Effects in Rats.
Accession No. 250786 Caswell No. 341 Tox review 004067.
Document (PDF) (538 KB PDF).
November 08, 1984. Memorandum. 2 Page(s).
Christine Chaisson. Toxicology Branch.
EPA Reg. No. 3125-183; Disulfoton (Di-Syston) Dominant Lethal Test in Mice;
Additional Information Caswell No. 341 Acc. 250895 Tox review 004053.
Document (PDF) (67 KB PDF).
November 08, 1984. Memorandum. 8 Page(s).
Christine Chaisson. Toxicology Branch.
EPA Reg. No. 3125-58; Disulfoton: Subacute Inhalation Study in the Rat
Caswell No. 341 Acc. 072293 Tox review 004087.
Document (PDF) (477 KB PDF).
December 05, 1984. Memorandum. 3 Page(s).
Ed Fite. Ecological Effects Branch.
Revision of Fish and Wildlife Support Chapter for the Disulfoton Registration Standard.
Document (PDF) (187 KB PDF).
February 08, 1985. Memorandum. 2 Page(s).
Christine Chaisson. Toxicology Branch.
EPA Reg. No. 3125-183; Disulfoton (Di-Syston) Evaluation of an interim report on chronic
feeding/oncogenicity of technical disulfoton in rats.
Document (PDF) (76 KB PDF).
February 18, 1988. Review. 20 Page(s).
John Noles. Ecological Effects Branch.
Reg. Nos. 3125-183 (3 Actions). Disulfoton (Di-Syston). Submission of Data in
Response to Registration Standard Attached:... Estuarine Organism Acute Toxicity
Studies. MRIDs 400716-01, -02, -03.
Document (PDF) (1022 KB PDF).
October 13, 1988. Summary. 9 Page(s).
Ecological Effects Branch.
EEB Chemical Profile - Disulfoton.
Document (PDF) (354 KB PDF).
December 04, 1991. DER. 4 Pages.
Kathryn Valente. Ecological Effects Branch.
Fish Early Life Stage (72-4). Test species: Rainbow Trout (Onchorhynchus mykiss).
MRID No. 419358-01.
Document (PDF) (451 KB PDF).
December 04, 1991. DER. 5 Pages.
Kathryn Valente. Ecological Effects Branch.
Aquatic Invertebrate Life Cycle (72-4). Test species: Daphnia magna.
MRID No. 419358-02.
Document (PDF) (484 KB PDF).
October 27, 1993. DER. 11 Pages.
J. Goodyear. EEB.
72-4. Estuarine Fish Early Life-Stage Toxicity Test. Species Tested: Sheepshead Minnow
(cyprinodon variegatus). MRID No. 426290-01.
Document (PDF) (1149 KB PDF).
February 06, 1997. DER. 18 Pages.
Kathryn V. Montague. EEB.
Aquatic Invertebrate Life Cycle Test Guideline 72-4 (B). Chronic Toxicity of
DISYSTON to the Mysid Shrimp (Mysidopsis bahia) Under Flow-Through Conditions.
MRID No.: 436109-01. DP Barcode: D215801.
Document (PDF) (2485 KB PDF).
April 21, 1997. Memorandum. 13 Page(s).
George Ghali. Health Effects Division.
RfD/ Peer Review report of Disulfoton (Disyston)...
Document (PDF) (1057 KB PDF).
June 18, 1997. DER. 29 Pages.
Kathryn Montague. Environmental Risk Branch III.
FISH LIFE-CYCLE TOXICITY TEST GUIDELINE 72-5. Di-Syston - The chronic toxicity
to the Sheepshead minnow. (Cyprinodon variegatus) during a full-life cycle exposure.
MRID No.: 439605-01.
Document (PDF) (1950 KB PDF).
April 23, 1998. Memorandum. 21 Page(s).
David Anderson. Reregistration Branch.
Disulfoton: Report of the Hazard Identification Assessment Review Committee
Tox review 012593.
Document (PDF) (1738 KB PDF).
July 08, 1998. Memorandum. 85 Page(s).
Kathryn Montague. Environmental Risk Branch III.
Reregistration Eligibility Document for Disulfoton (D237134) 'Attached to this
memorandum is the EFED RED chapter...'.
Document (PDF) (5565 KB PDF).
October 29, 1998. Memorandum. 267 Page(s).
David Anderson. Reregistration Branch 2.
Health Effects Division Reregistration Eligibility Decision Chapter for Disulfoton.
DP Barcode: D237133.
Document (PDF) (14475 KB PDF).
June 17, 1999. Memorandum. 61 Page(s).
Jonathan Becker. Reregistration Branch HED.
REVISED OCCUPATIONAL AND RESIDENTIAL EXPOSURE ASSESSMENT AND RECOMMENDATIONS FOR
THE REREGISTRATION ELIGIBILITY DECISION DOCUMENT FOR DISULFOTON. DP Barcode: D257368.
MRIDs 40469001, 40504105, and 42229401.
Document (PDF) (1887 KB PDF).
July 09, 1999. DER. 17 Pages.
Henry T. Craven. Ecological Effects Branch.
72-4 - Aquatic Invertebrate Life Cycle Test. Chronic Toxicity of 14C-Di-Syston
Sulfone to the Waterflea (Daphnia magna) Under Flow-Through Conditions.
MRID No.: 437380-01.
Document (PDF) (1734 KB PDF).
July 12, 1999. DER. 16 Pages.
Henry T. Craven. Ecological Effects Branch.
72-4 - Aquatic Invertebrate Life Cycle Test. Chronic Toxicity of 14C-Di-Syston
Sulfoxide to the Waterflea (Daphnia magna) Under Flow-Through Conditions.
MRID No.: 437380-02.
Document (PDF) (1655 KB PDF).
February 07, 2000. Memorandum. 31 Page(s).
David Anderson. Health Effects Division.
Risk Assessment and Reregistration Eligibility Decision (RED) Documents for
Disulfoton (Revised Risk Assessment, Phase 4). Chem. No. 032501, Rereg. Case No. 0102
DP Barcode: D262883. Sub DP Barcode of 237133. Tox review 014000.
Document (PDF) (1507 KB PDF).
June 15, 2000. Memorandum. 5 Page(s).
David Anderson. Reregistration Branch HED.
Disulfoton (PC Code 032501): HED's Response to Comments Submitted During
Phase 5 (Risk Management). DP Barcode D266111.
Document (PDF) (174 KB PDF).
August 24, 2000. Memorandum. 7 Page(s).
Jonathan Becker. Reregistration Branch HED.
Amendment to the the Disulfoton Occupational and Residential Exposure and Risk Assessment
(DP Barcode D268430).
Document (PDF) (261 KB PDF).
December 21, 2000. Memorandum. 13 Page(s).
David Anderson. Reregistration Branch 4 HED.
032501: 21-day dermal toxicity study in rabbits with disulfoton (MRID# 45239601).
[see OPP #34165B for copy of document.] Tox review 014448.
Document (PDF) (479 KB PDF).
December 21, 2000. Memorandum. 7 Page(s).
David Anderson. Reregistration Branch 4 HED.
032501: 1- and 3-day dermal toxicity study in rats 1% granular disulfoton (MRID# 45239602)
(Non-Guideline study) [see OPP #34165B for copy of document.] Tox review 014447.
Document (PDF) (13627 KB PDF).
May 31, 2001. Memorandum. 27 Page(s).
Shanna Recore. Reregistration Branch HED.
Revised Residential Exposure Assessment and Recommendation for the Reregistration
Eligibility Decision Document for Disulfoton. DP Barcode: D275170. MRID 45333401.
Document (PDF) (854 KB PDF).
June 27, 2001. Memorandum. 12 Page(s).
Christina Jarvis. Reregistration Branch HED.
DISULFOTON: Aggregate Risk Assessment (Revised) DP Barcode: D275171
Tox review 014610.
Document (PDF) (480 KB PDF).
August 18, 2005. Memorandum. 34 Pages.
Jess Rowland. Science Information Management Branch.
DISULFOTON: Data Evaluation Record of a Developmental Neurotoxicity Study.
DP Barcode: D288336. Reregistration Case #: 0102. MRID No. 45827601.
TXR#: 0051561.
Document (PDF) (1513 KB PDF).
June 02, 2006. Memorandum. 41 Pages.
David Anderson. Reregistration Branch 2.
6(a)(2) Data on disulfoton cholinesterase activity after acute dosing in young adults
and 11-day old pups at peak time [MRlD# 46589701-46589704], in maternal & fetal rats
[MRlD# 46635901, and in young adults dose 11 days [MRID# 46637101]…
Document (PDF) (1403 KB PDF).
Attachment(s) Following:
June 02, 2006. Memorandum.
David Anderson. Reregistration Branch 2.
(continued)...and 11 day old pups dosed for 11 days [MRlD# 46637101].
DP Barcode: D319813 and D321704. TXR# 0053636.
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