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Index of Cleared Science Reviews for DCNA (Pc Code 031301)
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Undated. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Acute Oral Toxicity - Rat MRID 0086879 from TXR No. 014663;
file R031844 page 120.
Document (PDF) (75 KB PDF).
Undated. DER. 22 Pages.
Paul Chin. Reregistration Branch 1 HED.
CHRONIC TOXICITY/CARCINOGENICITY FEEDING - RAT [OPPTS 870.4300 (OECD 453)]
MRID 46360701 (main study) & 46360702 (range-finding).
TXR#: 0053066. DP BARCODE: D294474.
Document (PDF) (1160 KB PDF).
Undated. Profile. 9 Page(s).
Ecological Effects Branch.
Disciplinary Review: Ecological Effects Profile. Technical DCNA.
Document (PDF) (374 KB PDF).
May 19, 1965. Review. 59 Page(s).
Gerald Boyack. The Upjohn Company.
To: William Stokes, Food and Drug Administration BOTRAN Tolerance Petition
5F0434 (Compilation - multiple documents re PP5F0434 from 1960's) HED file R103264.
Document (PDF) (1795 KB PDF).
June 11, 1965. Review. 7 Page(s).
George Whitmore. Petitions Review Branch.
Botran, tolerance request changes: apricots-10 ppm increased to 20 ppm; leaf
lettuce-5ppm increased to 10 ppm. Pesticide Petition No. 5F0434 Upjohn Chemical Company
Manufacturing process information on page 2 not included.
Document (PDF) (260 KB PDF).
May 12, 1966. Memorandum. 48 Page(s).
J. Wolff. Petitions Control Branch.
Memorandum of telephone conversation Between: Dr. A.J. Lemin, The Upjohn
Company, and J. Wolff Subject: PP #6F0474. Botran on various crops. (Compilation -
multiple documents re PP5F0474 from 1960's) HED file R103181.
Document (PDF) (1265 KB PDF).
January 08, 1967. Review. 26 Page(s).
Toxicology Branch HED.
Subacute human oral toxicity study; other tox studies. Manufacturing process
information on page 1 not included. Inert ingredient information on page 16 not included.
Document (PDF) (715 KB PDF).
February 21, 1967. Review. 39 Page(s).
William Stokes. Petitions Control Branch.
Botran 0.05 ppm in or on almond meats. 0.5 ppm in or on almond husks Pesticide
Petition No. 7F-0558 (Compilation - multiple documents re PP7F0558 from 1960's).
Document (PDF) (1408 KB PDF).
March 12, 1976. Review. 2 Page(s).
Scott Fredericks. Efficacy & Ecological Effects Branch.
RTF Review - Environmental Safety. Botran. 2,6-Dichloro-4-nitroaniline.
Inert ingredient information on page 1 is not included.
Document (PDF) (72 KB PDF).
June 26, 1978. Review. 5 Page(s).
John Doherty. Toxicology Branch.
EPA Reg. No. 1023-36 - Amended Registration The Upjohn Company; Botran 75W
Fungicide; eye irritation.
Document (PDF) (203 KB PDF).
August 08, 1979. Memorandum. 4 Page(s).
T. McLaughlin. Residue Chemistry Branch.
Memorandum of Conference (with Upjohn Co. Regarding Botran Metabolism).
Document (PDF) (197 KB PDF).
September 24, 1979. Review. 3 Page(s).
Robert Hitch. Efficacy & Ecological Effects Branch.
EUP - Kiwi Lustr and Botran. EUP and Temporary Tolerance for the Use of
DCNA and OPP on Kiwi Fruit.
Document (PDF) (111 KB PDF).
October 01, 1979. Memorandum. 4 Page(s).
E. Zager. Residue Chemistry Branch.
PP #9G2255 and 9G2256. 2,6-Dichloro-4-nitroaniline and O-phenylphenol in or on
Kiwi Fruit. Evaluation of Analytical Method and Residue Data. Inert ingredient and
manufacturing process information on pages 1-2 are not included.
Document (PDF) (256 KB PDF).
November 26, 1979. Memorandum. 5 Page(s).
L. Bradley. Residue Chemistry Branch.
PP #9E2268 and 9E2269. 2,6-Dichloro-4-nitroaniline and O-phenylphenol on Kiwi
Fruit. Evalution of Analytical Method and Residue Data. Inert ingredient and
manufacturing process information on pages 1-2 are not included.
Document (PDF) (470 KB PDF).
July 21, 1980. Memorandum. 3 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 4581-GUR. Decco Salt No. 22. Caswell Nos. 311, 375A.
Tox Review 000038.
Document (PDF) (233 KB PDF).
November 21, 1980. Memorandum. 4 Page(s).
Elizabeth Loevey. Residue Chemistry Branch.
PP #0F2368 and PP #0F2369. 2,6-Dichloro-4-nitroaniline and Analytical
Method and Residue Data. Inert ingredient and manufacturing process information
on page 2 are not included.
Document (PDF) (209 KB PDF).
December 22, 1980. Memorandum. 4 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA Registration No. 4581-341. Decco Salt #22. Caswell Nos. 311, 375A.
Tox Review 000471. Page 4 is not included - draft label.
Document (PDF) (387 KB PDF).
February 10, 1981. Memorandum. 6 Page(s).
Elizabeth Loevey. Residue Chemistry Branch.
PP #0E2419. Botran in or on Tomatoes. Evaluation of Residue Data and
Analytical Method. Inert ingredient and manufacturing processs information
on page 2 are not included.
Document (PDF) (335 KB PDF).
May 05, 1981. Review. 3 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. Nos. 81-NC-05, 81-VA-02. Botran. Use on Peanuts.
Document (PDF) (90 KB PDF).
January 19, 1982. Review. 4 Page(s).
Ann Stavola. Ecological Effects Branch.
Reg. No. 1023-36. Botran 95W Fungicide. Proposed Conditional Registration of Peanut Use.
Document (PDF) (184 KB PDF).
January 28, 1982. Review. 11 Page(s).
Willa Garner. Environmental Fate Branch.
Reg. No. 1023-36. Botran. Use on Peanuts. Pages 5-11 are not included - draft label.
Document (PDF) (141 KB PDF).
November 24, 1982. Review. 35 Page(s).
Toxicology Branch.
Review of Submitted Data. PP #2F2607, Registration No. 1023-36.
Accession Nos. 070501, 070502, 070503. MRIDs 29038, 29056, 82719, 82721, 82722.
Tox Review 002624.
Document (PDF) (4458 KB PDF).
April 20, 1983. Review. 14 Page(s).
Ecological Effects Branch.
DCNA Registration Standard - Nontarget Insects.
Document (PDF) (552 KB PDF).
July 05, 1983. Review. 4 Page(s).
Richard Moraski. Exposure Assessment Branch.
Petition #2F2607. Botran 75W. Amendment with Data.
Document (PDF) (180 KB PDF).
April 05, 1984. Memorandum. 4 Page(s).
Alex Arce. Toxicology Branch.
Botran 75W. Environmental Protection Agency Registration No. 1023-36.
Caswell #311. Tox Review 003765.
Document (PDF) (369 KB PDF).
October 22, 1984. Review. 7 Page(s).
Lionel Richardson. Exposure Assessment Branch.
Reg. No. 1023-57. Botran. Registration Standard.
Document (PDF) (215 KB PDF).
February 05, 1987. Review. 5 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 45639-128. Botran. Review of Protocol for Confined Rotational Crop Study.
Document (PDF) (210 KB PDF).
April 13, 1987. Memorandum. 6 Page(s).
Deloris Graham. Fungicide Herbicide Branch.
EPA File Symbol 2792-LL. Peach, Nectarine, Plum Lustr 274. Pages 5-6 are
removed, draft label. Acc 264871. Acute oral, acute dermal... Tox review 006247.
Document (PDF) (233 KB PDF).
April 17, 1987. Review. 4 Page(s).
Allen Vaughan. Ecological Effects Branch.
Reg. No. 87-OK-01. Botran 75W. Proposed Section 18 for Use on Peanuts in Oklahoma.
Document (PDF) (174 KB PDF).
September 30, 1987. Review. 7 Page(s).
Curtis Laird. Ecological Effects Branch.
Reg. No. 87-TX-11. DCNA (Botran). Proposed Section 18 for Control of Sclerotinia
Blight in Peanuts.
Document (PDF) (310 KB PDF).
January 28, 1988. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 45639-128. Botran. Review Request for Time Extensions for Submitting
Certain Studies Required under the DCNA Registration Standard.
Document (PDF) (109 KB PDF).
March 17, 1988. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 45639-110. Botran. Review of a Waiver Request for the Laboratory
Volatility Study Requirement.
Document (PDF) (81 KB PDF).
March 17, 1988. Review. 5 Page(s).
Emil Regelman. Exposure Assessment Branch.
Botran 75W. Request for Waiver of Volatility Data.
Document (PDF) (235 KB PDF).
April 06, 1988. Memorandum. 3 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 45639-110. Botran (DCNA). Time Extension Requests for Certain
Studies Required by the DCNA Registration Standard. RCB Nos. 3609, 3613.
No MRID Number.
Document (PDF) (323 KB PDF).
Attachment(s) Following:
March 09, 1988. Memorandum. 4 Page(s).
Maxie Jo Nelson. Residue Chemistry Branch.
EPA Reg. No. 45639-110. Botran (DCNA). Time Extension Requests for
Certain Studies. RCB No. 3176. No MRID Number.
*End of Attachments*
April 08, 1988. Review. 2 Page(s).
Norman Cook. Ecological Effects Branch.
Reg. No. 45639-110. DCNA Products. Time Extension Request for Submission
of Data as Requested Under 3(c)(2)(B).
Document (PDF) (66 KB PDF).
April 26, 1988. Memorandum. 4 Page(s).
Margaret Jones. Toxicology Branch.
DCNA; Review of Ames Assay. Tox Review 006698.
Document (PDF) (185 KB PDF).
April 28, 1988. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 45639-110. Botran. Review Request for Time Extensions for Submitting
Studies required under the Registration Standard.
Document (PDF) (103 KB PDF).
April 28, 1988. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
Reg. No. 45639-110. Botran. Review Waiver Request for the Laboratory Volatility
Study Requirement.
Document (PDF) (113 KB PDF).
April 29, 1988. Review. 5 Page(s).
Robert Pilsucki. Ecological Effects Branch.
Reg. No. 88-OK-01. Botran 75W (DCNA). Proposed Section 18 for Use on Peanuts.
Document (PDF) (265 KB PDF).
June 13, 1988. Memorandum. 21 Page(s).
Robert Jones. Toxicology Branch.
Section 18 Emergency Exemption for the Use of DCNA on Peanuts in Oklahoma.
Reconsideration of Earlier Request (Tox Ref. 8-0657, Record No. 220100).
Tox Review 006845. Pages 9-12 and 17-21 are not included - registrant data.
Document (PDF) (899 KB PDF).
June 13, 1988. Review. 7 Page(s).
Robert Pilsucki. Ecological Effects Branch.
Reg. No. 88-TX-04. Botran 75W (DCNA). Proposed Section 18 for Use on Peanuts.
Document (PDF) (384 KB PDF).
December 07, 1988. Memorandum. 3 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
EPA Reg. No. 45639-128. DCNA. Request for Time Extensions for the Submission
of Certain Studies Required by the DCNA Registration Standard. DEB #4450.
HED #8-1293. No MRID Number.
Document (PDF) (154 KB PDF).
April 21, 1989. Inventory. 12 Page(s).
Ecological Effects Branch.
List A Project. Inventory Summary Sheet - DCNA.
Document (PDF) (336 KB PDF).
May 31, 1989. Memorandum. 18 Page(s).
Clark Swentzel. Toxicology Branch.
Dicloran: Oncogenicity Study in Mice. Tox Review 007223.
Document (PDF) (469 KB PDF).
July 19, 1989. Memorandum. 1 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
EPA Reg. No. 45639-110. DCNA (Botran). Response to EFGWB Deferral re Vapor
Pressure. DEB #5416. HED #9-1563. MRID # n/a.
Document (PDF) (66 KB PDF).
August 10, 1989. Review. 14 Page(s).
Allen Vaughan. Ecological Effects Branch.
Reg. No. 89-OK-04. Botran. Proposed Section 18 for Use on Peanuts.
Document (PDF) (739 KB PDF).
September 29, 1989. Review. 8 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Reg. No. 89-TX-13. Botran 75W. Review Fish Accumulation Study Submitted in
Response to the 1983 Registration Standard.
Document (PDF) (252 KB PDF).
October 12, 1989. Memorandum. 2 Page(s).
Maxie Jo Nelson. Dietary Exposure Branch.
EPA Reg. No. 45639-128. DCNA. Transmittal of 8/10/89: 165-1 Study Submitted in
Response to the Registration Standard. DEB #5861. HED #9-2221. MRID #412038-00, -01.
Document (PDF) (71 KB PDF).
October 13, 1989. Memorandum. 9 Page(s).
Linda Taylor. Toxicology Branch.
Technical Dicloran - 21-Day Dermal Study in Rabbits. Tox Review 007547.
Document (PDF) (777 KB PDF).
December 21, 1989. Review. 3 Page(s).
Emil Regelman. Environmental Fate & Ground Water Branch.
Reg. No. 45639-128. Botran. Review Accumulation in Confined Rotational Crops Study.
Document (PDF) (107 KB PDF).
January 11, 1990. Review. 11 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No. 45639-128. Dicloran. Submission of Avian Acute Oral LD50 (Mallard)
in Response to RS.
Document (PDF) (677 KB PDF).
January 17, 1990. Review. 12 Page(s).
James Akerman. Ecological Effects Branch.
Reg. No. 45639-128. DCNA (Dicloran) Technical. Submitted in Response to RS.
Document (PDF) (667 KB PDF).
October 01, 1991. Memorandum. 9 Page(s).
Lucy D. Markarian. Precautionary Review Section.
EPA Reg. No. 2792-AU Dermal, inhalation, dermal sensitization. MRID 417757-01, 02.
Tox review 009276.
Document (PDF) (556 KB PDF).
March 15, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Somers test in Rabbits (A Special Study) MRID 00080869 from
TXR No 014663; file R031844 page 53.
Document (PDF) (105 KB PDF).
March 20, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Acute Dermal Toxicity - Rat MRID 0086894 from TXR No 014663;
file R031844 page 116.
Document (PDF) (74 KB PDF).
March 20, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Dermal Sensitization - Guinea pig MRID 0082721 from TXR No 014663;
file R031844 page 130.
Document (PDF) (71 KB PDF).
March 20, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Primary Dermal Irritation - Rabbit MRID 0086893 from TXR No 014663;
file R031844 page 108.
Document (PDF) (75 KB PDF).
March 20, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Primary Eye Irritation - Rabbit MRID 0086892 from TXR No 014663;
file R031844 page 112.
Document (PDF) (82 KB PDF).
March 20, 2001. DER. 8 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Developmental Toxicity in Rats Pages 6-8 removed, registrant data.
MRID No: 00127890 from TXR No 014663; file R031844 page 122.
Document (PDF) (212 KB PDF).
March 22, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Multigeneration Reproduction Study - Rat MRID 00102514, 0082269,
00082660, 00082673. from TXR No 014663; file R031844 page 73.
Document (PDF) (103 KB PDF).
March 27, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Subchronic (21-day) inhalation toxicity - rats, rabbits and dogs
(non-guideline). MRID 0086896 from TXR No 014663; file R031844 page 75.
Document (PDF) (104 KB PDF).
April 17, 2001. DER. 2 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Carcinogenicity Study - Feeding Rat MRID 00868903 from TXR No 014663;
file R031844 page 101.
Document (PDF) (110 KB PDF).
April 18, 2001. DER. 5 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Subchronic oral toxicity feeding - rats MRID 00029056 and 00082718.
from TXR No 014663; file R031844 page 103.
Document (PDF) (221 KB PDF).
April 24, 2001. DER. 7 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Two Year Chronic Toxicity - dog MRID 00029056 and 00082718 and 00026810.
from TXR No 014663; file R031844 page 77.
Document (PDF) (319 KB PDF).
April 26, 2001. DER. 13 Page(s).
P. V. Shah. Registration Action Branch HED.
STUDY TYPE: Combined chronic toxicity/carcinogenicity Page 13 removed,
registrant data. MRID No: 00029056 from TXR No 014663; file R031844 page 55.
Document (PDF) (446 KB PDF).
September 05, 2006. Memorandum. 26 Pages.
Jessica Kidwell. Cancer Assessment Review Committee.
DICLORAN: Report of the Cancer Assessment Review Committee.TXR No. 0054321.
Document (PDF) (902 KB PDF).