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Advancing the Ecological Assessment Process for Pesticides

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Why Revise the Assessment Process?

Provide Agency regulators with:

  1. Answers to risk management questions which could not be quantitatively addressed in the past, and

  2. Improved risk characterizations, focusing on magnitude, probability, and certainty of predictions.

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What Are The Risk Management Questions?

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How Did We Go About It?

Formed ECOFRAM (Ecological Committee on FIFRA Risk Assessment Methods), a stakeholder workgroup, in 1997.

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What Happened Next?

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What Does This Assessment Scheme Look Like?

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What About Moving Between the Levels?

Guidance will be developed to move to higher levels

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Where Are We Now?

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What Does The Aquatic Model Look Like?

Aquatic Organisms and Endpoints

Spatial Scale

Acute Risk

Chronic Risk

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What About the Aquatic Results for Acute Risk?

On average, 11% mortality is estimated, confidence limits of 2 - 27%. Infrequently (5% of time), Daphnia would be expected to incur ∼ 41% mortality (5 - 89%).

Aquatic Results for Acute Risk
5th percentile2 (<1-7)94 (86-99)
Median7 (1-22)98 (92-100)
Mean11 (2-27)96 (89-98)
95th percentile41 (5-89)100 (99-100)

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What Does the Terrestrial Model Look Like?

Effects Model

Uses distributions based on the dose/response curve to estimate and address


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What About the Terrestrial Results?

graphic of red-winged blackbird mortality curve - plotting y axis of cumulative probability vs. x-axis of minimum number of dead from 20-bird  groups

What About the Terrestrial Results?
95% probability that red-wing mortality will be greater than 9 out of 20 individuals (45% mortality)
There is a 5% probability that mortality will be greater than 80%.

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What Do the Regulators Say About the Models and Results?

To ensure assessment results can be used in regulatory decision-making, an ongoing dialogue is needed:

General Comments

Comments Related to Decision-making

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What Else Have We Been Doing?

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What Are the Next Steps?

Finish Level II modelsSpring
Develop training materials Summer
Hold trainingFall
Participate in peer review Winter

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OPP EFED Implementation Team

Position TitleName
ChairIngrid Sunzenauer, M.S.
Aquatic Team Donna Randall, M.S. (Lead)
Tim Bargar, Ph.D.
James Lin, Ph.D.
Terrestrial Team Ed Fite, M.S. (Lead)
Ed Odenkirchen, Ph.D.
Other Team Members Tim Barry, Sc.D. (Office of the Administrator)
David Farrar, M.S.
Stephanie Irene, Ph.D.
Douglas Urban, M.S.
EFED Technology Teams 
Former Team Members Kathryn Gallagher, Ph.D.
Les Touart, Ph.D.

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