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Computational Toxicology Research

ToxCast Chemical Data Challenges and Release

EPA’s high-throughput screening data on 1,800 chemicals is accessible through the interactive Chemical Safety for Sustainability Dashboards (iCSS dashboard). The iCSS dashboard provides user-friendly and customizable access to toxicity data from ToxCast and Tox21 high-throughput chemical screening technologies.

Using the TopCoder and InnoCentive crowd-sourcing platform Exit EPA Disclaimer, EPA invited the science and technology community to work with the data and provide solutions for how the new toxicity data can be used to predict potential health effects. The ToxCast data challenges focused on using this data and other publicly available data to predict the lowest effect level from traditional toxicity studies using laboratory animals. Challenge winners received awards for solving this challenge.

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