Newsroom
All News Releases By Date
REVISED POLICY ISSUED ON USE OF CHOLINESTERASE INHIBITION DATA IN PESTICIDE RISK ASSESSMENTS
Release Date: 09/07/2000
Contact Information:
FOR RELEASE: THURSDAY, SEPTEMBER 7, 2000
REVISED POLICY ISSUED ON USE OF CHOLINESTERASE
INHIBITION DATA IN PESTICIDE RISK ASSESSMENTS
EPA this week announced the availability of the revised science policy paper, “The Use
of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorus and Carbamate Pesticides.” The policy clarifies the Agency’s position that the inhibition of acetylcholinesterase by organophosphate and carbamate pesticides is the key event in causing harmful effects on nervous system function and outlines how EPA will consider various types of data in determining safe levels of exposure. Cholinesterase is an important enzyme that regulates levels of acetylcholine in the nervous system. Inhibition of cholinesterase can cause effects that increase in severity as the dose of the cholinesterase inhibitor increases. These effects can range from muscle tremors to various neurological effects to death. The revised paper is available at: https://www.epa.gov/pesticides/trac/science/. The Federal Register notice announcing the availability of this document is expected to be published Sept. 8.
R-130 # # #
Search this collection of releases | or search all news releases
View selected historical press releases from 1970 to 1998 in the EPA History website.
